• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6491-6496
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• 2012

Background: The influence of parental socio-economic status on childhood cancer treatment outcome in low-income countries has not been sufficiently investigated. Our study examined this influence and explored parental experiences during cancer treatment of their children in an Indonesian academic hospital. Materials and Methods: Medical charts of 145 children diagnosed with cancer between 1999 and 2009 were reviewed retrospectively. From October 2011 until January 2012, 40 caretakers were interviewed using semi-structured questionnaires. Results: Of all patients, 48% abandoned treatment, 34% experienced death, 9% had progressive/relapsed disease, and 9% overall event-free survival. Prosperous patients had better treatment outcome than poor patients (P<0.0001). Odds-ratio for treatment abandonment was 3.3 (95%CI: 1.4-8.1, p=0.006) for poor versus prosperous patients. Parents often believed that their child's health was beyond doctor control and determined by luck, fate or God (55%). Causes of cancer were thought to be destiny (35%) or God's punishment (23%). Alternative treatment could (18%) or might (50%) cure cancer. Most parents (95%) would like more information about cancer and treatment. More contact with doctors was desired (98%). Income decreased during treatment (55%). Parents lost employment (48% fathers, 10% mothers), most of whom stated this loss was caused by their child's cancer (84% fathers, 100% mothers). Loss of income led to financial difficulties (63%) and debts (55%). Conclusions: Treatment abandonment was most important reason for treatment failure. Treatment outcome was determined by parental socio-economic status. Childhood cancer survival could improve if financial constraints and provision of information and guidance are better addressed.

• 대한치과보철학회지
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• 제45권1호
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• pp.131-143
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• 2007

Statement of the problem: In case of poor bone quality or immediately loaded implant, various strategies have been developed focusing on the surface of materials to improve direct implant fixation to the bone. The microscopic properties of implant surfaces play a major role in the osseous healing of dental implant. Purpose of study: This study was undertaken to evaluate bone response of ion beam-assisted deposition(IBAD) of hydroxyapatite(HA) on the anodized surface of subperiosteal titanium implants. Material and methods: Two half doughnut shape subperiosteal titanium implants were made. The control group was treated with Anodized surface treatment and the test group was treated with IBAD of HA on control surface. Then two implants inserted together into the subperiosteum of the skull of 30 rats and histological response around implant was observed under LM(light microscope) and TEM(transmission electron microscope) on 4th, 6th and 8th week. Results: Many subperiosteal implants were fixed with fibrous connective tissue not with bony tissue because of weak primary stability. The control group observed poor bone response and there was no significant change at any observation time. However the test group showed advanced bone formation and showed direct bone to implant contact under LM on 8th week. The test group observed much rER in the cell of osteoblast but the control group showed little rER under TEM. Conclusions: The test group showed better bone formation than the control group at the condition of weak primary stability. With these results IBAD surface treatment method on Anodized surface, may be good effect at the condition of weak primary stability.

• 한국동물위생학회지
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• 제40권3호
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• pp.201-208
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• 2017

소에 있어서 BVDV는 반추류에서 중대한 감염을 야기하여 번식장애, 설사 및 유량감소를 야기하여 농가에 막대한 피해를 야기하고 있다. 특히 지속감염우의 확인과 도태는 농가 내 감염원을 제거하는 중요한 일이나 아직까지 PI개체의 바이러스의 감염과 전파에 관한 연구는 미진한 것으로 추정된다. 본 연구에서는 도입된 수컷에서 PI를 확인하였으며 전혈 검사를 실시 하면, PI 혈액 성상에서 림프구가 낮게 관찰되며 전체 WBC의 수는 정상범위에 속하나 낮게 나타나는 것을 알 수 있었다. PI 수컷에서 생산된 정액은 정자 수가 매우 낮으며, 신선 정액의 생존성도 불량한 것으로 조사되었다. 정자 기형율 또한 증가되었으며 특히 공포와 중편부의 소적을 가진 기형정자의 비율이 높았다. PI수컷은 나이가 들수록 정액 성상이 불량하여 불임화되었고 이는 BVDV가 정소의 정자 생산능력을 낮추어 사출된 정액내 정자수 감소 현상을 야기한다는 것을 알 수 있었다. 그럼에도 불구하고 확인된 PI 개체에 의한 전체군의 감염 현상은 관찰할 수 없었는데, 이는 적절한 백신 프로그램에 의하여 PI에 의한 간접적인 전파의 위험성이 낮다고 판단된다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제14권1호
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• pp.123-127
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• 2003

Cornelia de Lange 증후군은 여러 신체 기관의 선천적 기형과 성장지연, 신경 발달학적 이상을 동반하는 질환이다. 어떠한 생화학적 혹은 염색체 표지자도 아직까지 Cornelia de Lange 증후군에 특이적인 소견은 발견되지 못하였고 진단은 임상적인 관찰에 전적으로 의존하게 되어있다. 따라서 임상가의 경험이 본 질환의 발견에 중요한 만큼 저자들은 정신지체와 자폐장애를 보이는 Cornelia de Lange 증후군 사례를 보고하는 바이다. 본 증례의 환아는 6세 4개월의 여환으로 걷기 등의 운동발달이 늦었다고 하며 현재까지도 한단어도 말하지 못하는 심각한 언어지체를 보였다. 또한 눈 맞춤이 빈약하고 타인과 정서적 교류가 되지 않는 등 사회적 상호작용의 저하와 상동행동을 보였으며 따라서 정신지체와 자폐장애로 진단 할 수 있었다. 환아는 저신장을 보였고 눈썹이 짙고 속눈썹도 길고 짙었으며 치아 간격이 넓고 코 끝이 들려 있었으며 입주위에 수염이 나 있었다. 낮은 헤어라인을 보였고 몸통과 사지에 다모증을 보였으며 손가락은 짧은 편이었다. 방광 요관 역류와 잦은 상기도 감염과 폐렴의 과거력이 있었고 4차례 열성경련이 있었다. 본 증례의 경우 특징적인 얼굴 모습과 성장발달지연, 정신지체, 행동양상, 동반된 내과적 질환의 병력 등으로 Cornelia de Lange 증후군으로 진단할 수 있었다.

• 한국학교ㆍ지역보건교육학회지
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• 제1권1호
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• pp.119-130
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• 2000

The purpose of this study was to serve as a basis for more effective sex education, by examining the influence of obscene media on elementary school student's sex consciousness. For attaining the purpose, the research questions were posed as follows: 1) What's general characteristics of elementary school students? 2) How much are elementary school students exposed to obscene media? 3) Is their sex consciousness different according to the degree of being exposed to obscene media and the appearance of secondary sex characteristic? The subject of study were the 400 male and female students who were in the sixth grade at elementary school in the city of Paju. The questionnaire survey was conducted to find out their general characteristics, sex consciousness and degree of being exposed to obscene media. The conclusions were as follows; 1) Basic Information 94% of the students investigated were living with their parents. The greatest number of their parents were in their fourties. Concerning the religion of their families, 47.5% belonged to Christianity or Catholicism. 47.3% got in touch with obscene media, which indicated that the harmful influence of that media was great. Their basic knowledge of pregnancy was very poor, as 27.2% weren't sure whether being pregnant could be caused only by shaking hands, hugging or kissing. 34.7% considered it a natural behavior to contact the other sex. Regarding their practice of sexual behavior, they'd have an experience of hugging or kissing. 2) Group Comparison The female students underwent the appearance of secondary sex characteristic faster than the male students. As a result of examining if their degree of being exposed to obscene media was affected by the presence or absence of secondary sex characteristic, no statistically significant difference existed in all the groups: the entire group, male student group and female student group. There appeared, however, statistically significant differences between male and female students, as the number of male student who hadn't yet been exposed to obscene media was less than that of female student who hadn't. And the number of male student who had been much exposed to obscene media was more than that of female student who had. 3) Sex Knowledge, Sex Attitude and Sex Practice The extent of making contact with obscene media didn't make statistically significant difference to the sex knowledge of all the groups. But more extent of getting in touch with obscene media led to more sex attitude and sex practice in the entire group. However, as a result of analyzing these things by the presence or absence of secondary sex characteristic, it's found in general that the group that had secondary sex characteristic possessed statistically better sex knowledge than the other group that hadn't. For the male students, there appeared little disparities in three subareas of sex knowledge, sex attitude and sex practice. For the female students, however, the group that had secondary sex characteristic owned better sex knowledge than the other group that hadn't, and the former group looked upon sex attitude as more natural.

• 대한치과보철학회지
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• 제28권2호
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• pp.1-28
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• 1990

The severe atrophic edentulism with poor neuromuscular control militates against successful conventional denture therapy. To such situation, a prescribing of dental implant treatment has been considered with some probability. Implant materials used as a trial for dental implants includes metals, plastic polymers and ceramics. The purpose of this study was to observe histologic response in osseointegration process at titanium implant-tissue interface based on biocompatibility at specific period of sequential natures which were divided into a half month, one, month, two months, three months and immediate as a base line. In this study, unilateral lower left premolar and molar teeth were extraced in three dogs. After allowing to heal for 6 months, three kinds of osseointegrated implant, $Br{\aa}nemark$, Corevent and kimplant(a prototype of SNU implant study)were inserted in each dog respectively according to the above sequence from front to back. The specimens were taken from those dogs at the same time since implant were inserted quite reverse order of the specified periods, and decalcified and processed for histologic examination for the light microscopy and the electron microscopy. The microscopic histologic findings at the interface between titanium implants and tissue were interpretated as follows : A. Light microscopic findings : a. Immediate : Implant were surrounded by compact bone and spongy bone. Microcrak was observed in the superficial bone tissue. Osteocytes were disappeared and bone lacunae were observed as a vacant space in some parts. In the contacting with the spongy bone, bone trabeculae and bone marrow were in contact with the implant. b. A half Month : Osteoblasts exist as a monolayer in th inner bone trabeculae and do bone additiocn. Osteoblasts&inflammatory cells were observed in some parts. c. One Month : The presence of osteoclasts decreased. Osteoblasts did active bone fromation, and bone marrow was in contact with the implant in the many places. d. Two Months : Bone formation was advanced in comparison with the b and c. The presence of osteoclsts was not observed. e. Three Months : The superficial bone tissue contacted with the implants was entirely composed by the compact bone. B. Electron microscopic findings : a. A half month and one month group : In the parts of the active bone formation, osteoblasts with the well developed endoplasmic reticulum and Golgi apparatus were arranged in the monolayer. In the parts of the bone resorption, ruffled border was well developed and many osteoclasts with the well-developed golgi apparatus, mitochondria, vacuole, vesicle and lysosome were existed. b. Three months group : No osteoblasts were observed in the superficial bone tissue. Bone matrix with collaen fiber was observed. c. No significant dirrerence in the histologic findings was observed in $Br{\aa}nemark$, Core-vent and kimplant.

• Journal of Preventive Medicine and Public Health
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• 제31권2호
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• pp.293-309
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• 1998

The purpose of this study is to compare the level of health-related quality of life and relating factor between institutional elderly and community living elderly. The subjects were 390 from Sanatorium or Nursing home and 467 from the community in Kwangju. The results are followed : 1) A comparison of ADL between two groups, institutional elderly and community living elderly, resulted in that community elderly were more significantly independent in the areas of bathing and transfer than institutional elderly. 2) A comparison of IADL between two groups resulted in that : Community elderly were more independent in the areas of using telephone and transportation, food preparation, house keeping, and doing laundry. Institutional elderly were more independent in the area of handling finances. 3) In the case of poor health-related quality of life, institutional elderly showed 2.4 times in the dimension of physical fitness, 1.8 times in daily activity, 2 times in social activity, 2 times in pain, 26.7 times in social support, and 0.4 times in subjective quality of life higher than community elderly There was no significant differences in the rest of dimensions. 4) In institutional elderly, the analysis of variables related to the health-related quality of life resulted in that; The relating factors were sex, education, and chronic illness in the dimension of physical function. Direct contact with family or significant others in the dimension of social activity. Chronic illness in the dimension of pain and perceived health status. Direct or indirect contact with family or significant others over the phone or through letters in the dimension of social support. 5) The analysis of variables related to the health-related quality of life showed that community elderly has more relating variables in each area than institutional elderly. The relating factors were age, sex, and chronic illness in the dimension of physical function. Education and chronic illness in the dimension of emotional status. Age and chronic illness in the dimension of daily activity and social activity Education and chronic illness in the dimension of pain and perceived health status. Sex, education, family size in the dimension of social support. Education and chronic illness in the dimension of subjective quality-of-life. Throughout general daily activity, community elderly showed more satisfactory results than institutional elderly, but in the subjective area of health-related quality of life, such as subjective quality of life, institutional elderly group showed more positive results. And community elderly had more relating factors than institutional elderly. For the health care of the elderly that focused on quality of life, new approaches considering the characteristics of both group, institutional and community living elderly, are needed.

• Journal of Radiation Protection and Research
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• 제23권3호
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• pp.175-184
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• 1998

1998년에 고리 1호기로부터 교체될 증기발생기의 선량율을 계산하기 위하여 Smear 오염검사 결과와 튜브 손상원인을 규명하기 위하여 인출하였던 증기발생기 튜브의 선량을 측정결과로부터 증기발생기 내부의 방사성핵종 재고량을 평가하였다. 방사성 핵종 재고량을 토대로 QAD-CG 컴퓨터 코드를 이용하여 증기발생기 표면의 접촉 선량율과 1 m 이격 선량율을 계산하였는데, 접촉 선량율은 Channel Head의 하부에서 최저인 11.5 mR/hr를 나타냈으며, Shell Barrel의 중간 지점에서 최대값인 37.7 mR/hr를 나타냈다. 한편 접촉 선량율과 1 m 이격 선량율은 증기발생기의 크기로 인해 큰 차이를 보이지 않았다 또한 증기발생기의 차폐가 필요할 경우 요구되는 기본적인 데이터를 마련하기 위하여 납과 탄소강의 차폐 특성을 비교해 보았다. 납을 차폐체로 사용할 경우 2 mm 두께만으로도 증기발생기 Shell Barrel 중간 지점에서의 표면 선량율이 37.7 mR/hr에서 15.7 mR/hr로 감소되었다. 그러나 탄소강의 경우에는 차폐체의 두께를 2 cm로 증가시킨다고 하더라도 차폐효과가 매우 낮았다. 이러한 차폐효과 차이는 저에너지 광자에 대한 납과 탄소강의 감쇄효과 차이와 축적인자 차이 때문에 발생되는 것으로 추정된다.

• The Journal of Advanced Prosthodontics
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• 제1권1호
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• pp.19-25
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• 2009

STATEMENT OF PROBLEM. Primary stability at the time of implant placement is related to the level of primary bone contact. The level of bone contact with implant is affected by thread design, surgical procedure and bone quality, etc. PURPOSE. The aim of this study was to compare the initial stability of the various taper implants according to the thread designs, half of which were engaged to inferior cortical wall of type IV bone(Group 1) and the rest of which were not engaged to inferior cortical wall(Group 2) by measuring the implant stability quotient(ISQ) and the removal torque value(RTV). MATERIAL AND METHODS. In this study, 6 different implant fixtures with 10 mm length were installed. In order to simulate the sinus inferior wall of type IV bone, one side cortical bone of swine rib was removed. 6 different implants were installed in the same bone block following manufacturer s recommended procedures. Total 10 bone blocks were made for each group. The height of Group 1 bone block was 10 mm for engagement and that of group 2 was 13 mm. The initial stability was measured with ISQ value using Osstell $mentor^{(R)}$ and with removal torque using MGT50 torque gauge. RESULTS. In this study, we found the following results. 1. In Group 1 with fixtures engaged to the inferior cortical wall, there was no significant difference in RTV and ISQ value among the 6 types of implants. 2. In Group 2 with fixtures not engaged to the inferior cortical wall, there was significant difference in RTV and ISQ value among the 6 types of implants(P < .05). 3. There was significant difference in RTV and ISQ value according to whether fixtures were engaged to the inferior cortical wall or not(P < .05). 4. Under-drilling made RTV and ISQ value increase significantly in the NT implants which had lower RTV and ISQ value in Group 2(P < .05). CONCLUSIONS. Without being engaged to the inferior cortical wall fixtures had initial stability affected by implant types. Also in poor quality bone, under-drilling improved initial stability.

• 유통과학연구
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• 제12권8호
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• pp.91-102
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• 2014

Purpose - Today, the importance of the service industry has increased. Social welfare businesses that follow the non-profit principle have neglected the distribution of the service. However, an intangible service, when produced and consumed, has a similar service delivery system to common service distribution and social welfare. Therefore, the author has assumed the efficiency of the service delivery system of social welfare to be equivalent to the service distribution industry. Hence, various kinds of social welfare services for the prevention of elderly suicide, from the perspective of distribution, are discussed. Studies on generational relations have thus far investigated depression from parent-children conflict, and satisfaction with their lives. Studies on the relationship between family solidarity and elderly suicide by analyzing existing social problems are rare. This study investigated the effects of family solidarity between old parents and adult children upon elderly suicide by analyzing serious psychological and social problems. This study revealed basic measures for elderly suicide prevention through services that could elevate family solidarity from the perspective of social welfare service distribution. Research design, data, and methodology - The subjects were 468 elderly, 65 years or older, at 18 senior welfare centers and halls for the elderly at Seoul and Gyeonggi-do. Questionnaire surveys, excluding invalid answers, were analyzed. Convenience sampling was used from February 5, 2014 to March 5, 2014. The findings were: First, women and those having spouses with advanced educational backgrounds and social activities had primary solidarity such as contact solidarity, affectionate solidarity, functional solidarity (giving help), and functional solidarity (receiving help). In addition, those who had good health, from a subjective point of view, had more solidarity. Second, the elderly who were men and single, and who had poorer educational backgrounds thought of suicide, lacked social activities, and had poor health, from a subjective point of view. Third, family solidarity between old parents and adult children had significantly negative influence on the suicidal ideation of the elderly. Results - The study revealed the following implications. First, the preparation for old age should consider not only economic welfare but also the psychological welfare due to the relationship with children. Second, the phenomenon of elderly suicide because of a lack of family solidarity could increase national loss and have great influence upon welfare in old age. Therefore, planning of welfare services for the elderly should consider the value of relationships with children to improve the psychological welfare of the elderly. Third, the social expenses of government-oriented support for parents should be discussed from the people's point of view. Conclusions - The subjects of the study comprised the elderly at Seoul and Gyenggi-do; therefore, it would be difficult to extrapolate the findings to all the elderly in the nation. The subject visited senior welfare centers as well as halls for the elderly; therefore, it would be difficult to assume that the trends were representative of the elderly in the nation.