• 제목/요약/키워드: Pooling

검색결과 316건 처리시간 0.023초

Development of Molecular Markers for Xanthomonas axonopodis Resistance in Soybean

  • Kim Ki-Seung;Van Kyujung;Kim Moon Young;Lee Suk-Ha
    • 한국작물학회지
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    • 제49권5호
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    • pp.429-433
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    • 2004
  • A single recessive gene, rxp, controls the bacterial leaf pustule (BLP) resistance in soybean and in our previous article, it has been mapped on linkage group (LG) D2 of molecular genetic map of soybean. A total of 130 recombinant inbred lines (RILs) from a cross between BLP-resistant SS2-2 and BLP-susceptible Jangyeobkong were used to identify molecular markers linked to rxp. Fifteen simple sequence repeat (SSR) markers on LG D2 were screened to construct a genetic map of rxp locus. Only four SSR markers, Satt135, Satt372, Satt448, and Satt486, showed parental polymorphisms. Using these markers, genetic scaffold map was constructed covering 26.2cM. Based on the single analysis of variance, Satt372 among these four SSR markers was the most significantly associated with the resistance to BLP. To develop new amplified fragment length polymorphism (AFLP) marker linked to the resistance gene, bulked segregant analysis (BSA) was employed. Resistance and susceptible bulks were made by pooling equal amount of genomic DNAs from ten of each in the segregating population. A total of 192 primer combinations were used to identify specific bands to the resistance, selecting three putative AFLP markers. These AFLP markers produced the fragment present in SS2-2 and the resistant bulk, and not in Jangyeobkong and the susceptible bulk. Linkage analysis revealed that McctEact97 $(P=0.0004,\;R^2=14.67\%)$ was more significant than Satt372, previously reported as the most closely linked marker.

과학 영재 관찰.추천 선발 방식에 대한 교사의 인식 조사 및 개선 방안 (The Teachers' Recognition and a Plan for the Improvement of the System on Selection of Gifted Students in Science Using Teachers' Observation and Nomination)

  • 방미선;김용권
    • 한국초등과학교육학회지:초등과학교육
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    • 제32권2호
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    • pp.169-184
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    • 2013
  • The purpose of this study is to investigate teachers' recognition and to suggest an improvement in the system of teacher's observation and nomination used to selecting gifted and talented students in Science in the Busan Metropolitan School District in 2013 by investigating teachers' recognition of the system and their expressed needs. The results are as follows. First, it was observed that teachers are of the opinion that it is difficult to determine the science gifted students by observation due to their lack of expertise in giftedness and gifted education, the lack of a check list to use, and the difficulty of ensuring the objectivity of the results of the determination. Second, the absence of objective screening tools used for the selection, the selection of gifted students based on their subjective judgment, and the possibility to select students based only on visible manifestations of ability may cause parents to mistrust the system. Thus, institutional support is required to address the concerns of teachers and parents. Third, the teachers who are in charge of observation, nomination, selection and determination need to be trained. After that, at least one of these teachers should be assigned in each school and training should operate continuously and systematically. Lastly, while these things are occurring, the process of observation and nomination of by teachers, which is the basis of pooling gifted students at the level of Busan Metropolitan School District, should be continued.

Alcohol Consumption and Breast Cancer Survival: A Metaanalysis of Cohort Studies

  • Gou, Yun-Jiu;Xie, Ding-Xiong;Yang, Ke-Hu;Liu, Ya-Li;Zhang, Jian-Hua;Li, Bin;He, Xiao-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권8호
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    • pp.4785-4790
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    • 2013
  • Background and Objectives: Evidence for associations between alcohol consumption with breast cancer survival are conflicting, so we conducted the present meta-analysis. Methods: Comprehensive searches were conducted to find cohort studies that evaluated the relationship between alcohol consumption with breast cancer survival. Data were analyzed with meta-analysis software. Results: We included 25 cohort studies. The meta-analysis results showed that alcohol consumption was not associated with increased breast cancer mortality and recurrence after pooling all data from highest versus lowest comparisons. Subgroup analyses showed that pre-diagnostic or post-diagnostic consumpotion, and ER status did not affect the relationship with breast cancer mortality and recurrence. Although the relationships of different alcohol consumption with breast cancer mortality and recurrence were not significant, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence. Only alcohol consumption of >20 g/d was associated with increased breast cancer mortality, but not with increased breast cancer recurrence. Conclusion: Although our meta-analysis showed alcohol drinking was not associated with increased breast cancer mortality and recurrence, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence and alcohol consumption of >20 g/d was associated with increased breast cancer mortality.

Die spacer의 두께에 따른 복합레진 inlay의 치은 변연부 미세누출 및 접착양태에 관한 연구 (GINGIVAL MARGIAL LEAKAGE AND BONDING PATTERN OF THE COMPOSITE RESIN INLAY ACCORDING TO VARIOUS THICKNESS OF DIE SPACER)

  • 박태일;신동훈;홍찬의
    • Restorative Dentistry and Endodontics
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    • 제20권1호
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    • pp.152-163
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    • 1995
  • This experiment was performed to observe the adhesion pattern and microleakage in the gingival margin according to variation in the resin cement thickness which results from thickness of Die spacer. which is considered to effect the adaptability of the composite resin inlays. Clearfil CR inlays were fabricated on stone models with CR Sep applicated once and Nice fit twice, 4 times, and 6 times each. After 2nd curing within the CRC-100 oven, CR inlays were cemented with CR inlay cement. Dye(2% methylene blue) penetration and adhesion pattern were evaluated after sectioning of gingival margin into :3 pieces. The results were as follows ; 1. The thickness of resin cement showed unevenchanging pattern with that of die spacer, namely, it was increased until 4 times' application of Nice-Fit but was decreased with 6 times' application of that. 2. The degree of dye penetration wasn't affected by cement thickness within a limited value. 3. Most of dye penetration was shown through the interface between cement and enamel rather than the interface between cement and CR inlay. This shows that the affinity of resin cement for CR inlay was superior to the adhesive strength with tooth structure. 4. No gap was found at the interface between enamel and cement but some showed separation between dentin and cement. It is concidered that the contraction force of cement was less than the bond strength with the enamel. 5. Lots of voids were found in the CR inlay and resin cement. There was a pooling tendency of bonding agent and cement in the axiogingival line angle portion. 6. In some specimens, cracks were shown in enamel margin. From this it could be considered that cavity preparation and surface treatment weakened the tooth structure.

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직업성 전자장 노출과 백혈병 발생에 관한 메타분석 (Relationship between Occupational Electromagnetic Field Exposure and Leukemia : A Meta-Analysis)

  • 김윤신;송혜향;홍승철;조용성
    • Journal of Preventive Medicine and Public Health
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    • 제33권1호
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    • pp.125-133
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    • 2000
  • Objectives : This study uses meta-analysis methodology to examine the statistical consistency and importance of random variation among results of epidemiologic studies of occupational electromagnetic field exposure and leukemia. Methods : Studies for this meta-analysis were identified from previous reviews and by asking researcher active in this field for recommendations. Overall, 27 studies of occupational electromagnetic field exposures and leukemia were reviewed. A variety of meta-analysis statistical methods have been used to assess combined effects, to identify heterogeneity, and to provide a single summary risk estimate based on a set of simiar epidemiologic studies. In this study, classification of exposure metircs on occupational epidemiologic studies are reported for (1) job classification (20 individual studies); (2) leukemia subtypes (13 individual studies); and (3) country (27 individual studies). Results : Results of this study, an inverse-variance weighted pooling of all the data leads to a small but significant elevation in risk of f 1% (OR=1.11, 95% CI : $1.06\sim1.16$) among 27 occupational epidemiologic studies. Publication bias was assessed by the 'fail-safe n' that may be not influence for all combined results exception a few categories, ie, 'power station operators' and 'electric utility workers' by job classification on occupational study. And ail combined odds ratio results were similar for fixed-effects models and random-effects models, with slightly higher risk estimates for the random-effects model in situations where there was significant heterogeneity, ie, Q-statistic significant (p<.05). Conclusions : We found a small elevation in risk of leukemia, but the ubiquitous nature of exposure to electromagnetic fields from workplace makes even a weak association a public health issue of substantial power to influence the present overall conclusion about relationship between electromagnetic fields exposure and leukemia.

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한국남해안일대의 장염비브리오 분포연구 - 제주, 거제, 남해, 욕지, 부산 및 마산 근해의 해수 해저펄 및 해산물에서 장염비브리오 분리 - (Studies on Vibrio Parahaemolyticus on the Southern Seas of Korea - On the Isolation of V. Parahaemolyticus from Sea Water, Sea Mud and Marine Products in Jeju Keoje, Namhae, Yockji, Busan and Masan -)

  • 주진우
    • 대한미생물학회지
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    • 제18권1호
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    • pp.1-9
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    • 1983
  • The author studied on the distribution of V. parahaemolyticus among sea water, sea mud, and various marine products in Jeju, Keoje, Namhae, Yockji, Busan, and Masan on the southern seas of Korea from winter in 1981 to summer in 1982. The author studies for the isolated strains to bacteriological identification Kanagawa phenomenon(hemolytic activity) on Modified Wagatuma blood agar plates and serotypes with anti V. parahaemolyticus. The results obtained were as follows:. 1. V. parahaemolyticus was isolated in 713 strains(28.3%) among 2519 total specimens of sea water, sea mud, and various marine products. 2. The isolation rates of V. parahaemolyticus in summer season were higher than in spring and winter season. Above results were 304 strains(32.6%) among 932 specimens in summer, 160 strains (28.1%) among 570 specimens in spring, 149 strains(14.6%) among 1017 specimens in winter, respectively. 3. The hemolysis on Modified Wagatuma agar added human erythrocytes was 66.0% of positive Kanagawa phenomenon, and was 34.0% of negative Kanagawa phenomenon, respectively. 4. The distributions of serotypes of V. parahaemolyticus isolated were from KI to K VIII of K pooling antisera. The results were 6 strains(6.6%) on K 1 of K I, 14 strains(l5.5%) on K 17 of K II, 26 strains(28.8%) on K 28 of K IV. 10 strains(11.1%) on K 32 of KV, 4 strains(4.4%) on K 39 of KV, 8 strains(8.8%) on K 42 of K VI, 2 strains(2.2%) on K 48 of K VII, 1 strain(1.1%) on K 50 of K II and 7 strains(7.7%) on K 55 of K VII, respectively. 5. V. parahaemolyticus was more frequently isolated from sea mud than sea water and various marine prdoucts in winter season. 6. There was no great difference as far as the distribution of V. parahaemolyticus concerned in Jeju, Keoje, Namhae, Yockji, Busan and Masan of the southern seas of Korea.

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Image Quality Assessment by Combining Masking Texture and Perceptual Color Difference Model

  • Tang, Zhisen;Zheng, Yuanlin;Wang, Wei;Liao, Kaiyang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제14권7호
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    • pp.2938-2956
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    • 2020
  • Objective image quality assessment (IQA) models have been developed by effective features to imitate the characteristics of human visual system (HVS). Actually, HVS is extremely sensitive to color degradation and complex texture changes. In this paper, we firstly reveal that many existing full reference image quality assessment (FR-IQA) methods can hardly measure the image quality with contrast and masking texture changes. To solve this problem, considering texture masking effect, we proposed a novel FR-IQA method, called Texture and Color Quality Index (TCQI). The proposed method considers both in the masking effect texture and color visual perceptual threshold, which adopts three kinds of features to reflect masking texture, color difference and structural information. Furthermore, random forest (RF) is used to address the drawbacks of existing pooling technologies. Compared with other traditional learning-based tools (support vector regression and neural network), RF can achieve the better prediction performance. Experiments conducted on five large-scale databases demonstrate that our approach is highly consistent with subjective perception, outperforms twelve the state-of-the-art IQA models in terms of prediction accuracy and keeps a moderate computational complexity. The cross database validation also validates our approach achieves the ability to maintain high robustness.

재난관리자의 역할에 관한 탐색적 연구 - 지방자치단체의 재난관리 실무책임자를 중심으로 - (An Exploratory Study on the Role of Disaster Managers - Based on disaster management officers at the local government -)

  • 방기성
    • 한국방재안전학회논문집
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    • 제5권2호
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    • pp.35-42
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    • 2012
  • 지방자치단체 재난관리부서 실무책임자(재난관리자)의 역할은 주민들의 생명과 재산을 담보하는 업무의 중요성에도 불구하고, 이들의 역할과 책임에 대한 구체적 연구결과나 문헌조차 없는 실정으로 이들의 역할정립이 시급한 시점이다. 본 연구에서는 일반 행정관리자의 역할과는 달리 재난이라는 특수한 상황 속에서 재난관리자가 수행해야할 차별화된 위상과 역할을 국내외 문헌들에 대한 고찰을 통해 정립해 봄을 목적으로 한다. 재난관리자의 역할이 일반 행정관리자의 역할과 상당부분 유사한 부분이 있다고 보여지지만, 인명 및 재산보호나 특수영역으로서 전문가적 역할도 강조되어야 한다는 점이 차별화 되었다. 재난관리 단계별로 예방, 복구 등의 업무 수행에 있어서는 중하위직에서 이루어지는 관리업무가 주류를 이루고 있는 반면, 대비 및 대응단계의 업무수행은 긴박한 의사결정지원, 인접부서 또는 타기관간의 협조와 조정, 주민설득, 자원의 동원 등 대내외적 조정, 통제역량 및 정무적 판단능력이 수반되어야 하므로 중상층 이상의 관리자 역할이 요구된다.

Multi-parametric MRIs based assessment of Hepatocellular Carcinoma Differentiation with Multi-scale ResNet

  • Jia, Xibin;Xiao, Yujie;Yang, Dawei;Yang, Zhenghan;Lu, Chen
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제13권10호
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    • pp.5179-5196
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    • 2019
  • To explore an effective non-invasion medical imaging diagnostics approach for hepatocellular carcinoma (HCC), we propose a method based on adopting the multiple technologies with the multi-parametric data fusion, transfer learning, and multi-scale deep feature extraction. Firstly, to make full use of complementary and enhancing the contribution of different modalities viz. multi-parametric MRI images in the lesion diagnosis, we propose a data-level fusion strategy. Secondly, based on the fusion data as the input, the multi-scale residual neural network with SPP (Spatial Pyramid Pooling) is utilized for the discriminative feature representation learning. Thirdly, to mitigate the impact of the lack of training samples, we do the pre-training of the proposed multi-scale residual neural network model on the natural image dataset and the fine-tuning with the chosen multi-parametric MRI images as complementary data. The comparative experiment results on the dataset from the clinical cases show that our proposed approach by employing the multiple strategies achieves the highest accuracy of 0.847±0.023 in the classification problem on the HCC differentiation. In the problem of discriminating the HCC lesion from the non-tumor area, we achieve a good performance with accuracy, sensitivity, specificity and AUC (area under the ROC curve) being 0.981±0.002, 0.981±0.002, 0.991±0.007 and 0.999±0.0008, respectively.

잔존 봉합사에 의해 발생한 점액종 (MUCOCELE CAUSED BY UNREMORED SUTURE SILK : A CASE REPORT)

  • 서원건;최병재;최형준;이제호
    • 대한소아치과학회지
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    • 제26권4호
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    • pp.664-668
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    • 1999
  • 점액종이란 소타액선 분비관의 폐쇄 또는 파열로 인한 타액의 저류로 나타나는 종창에 대한 임상적인 용어이다. 점액종은 조직학적으로 삼출형과 잔류낭종형으로 분류되며, 삼출형은 외상등으로 소타액선 분비관이 파열된 후 점액이 조직내로 유출되어 조직간격에 고여있는 상태이기 때문에 상피 피복을 볼 수 없고 낭종벽은 육아조직으로 둘러싸여있다. 그리고 잔류낭종형은 소타액선 분비관이 작은 타석에 의해 폐쇄되거나 분비관 주위 반흔조직의 협착으로 발생하며 낭종강은 원주상피 또는 위중층 편평상피로 피개되어 있다. 본 증례는 3년전 하순의 열창 치료를 위해 봉합된 후 발사되지 않는 silk 봉합사에 의해 발생한 점액종의 치험례로, 발사되지 않은 봉합사가 하순 소타액선의 분비관을 관통하여 파열시켜서 점액이 결체조직으로 유출되어 점액종이 발생하였다.

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