• 한국미생물·생명공학회지
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• 제35권2호
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• pp.81-97
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• 2007

Punica granatum, L. (Pomegranate) has 613 seeds which accidentally corresponds to the 613 commandments in the Bible. Accordingly, the fruit has been worshipped by the Jewish and other religious people from the ancient. Pomegranate's seed, peel and juice contain a variety of ethnomedical components so much as the sum of three kinds of other common fruits. The number of published papers related to the pomegranate in recent 7 years flourished 7 times more than before at the bases of Medline record. Since the containments of estrogen, as $17{\alpha}-estradiol,\;17{\beta}-estradiol$, estrone, and estradiol, etc., in pomegranate have been reported, public interests and commercial values of pomegranate arose considerably. The report was disproved later, however, merits of this fruit remained yet; clinical efficacy for preventing and remediating cancers including breast and prostate cancers by oral administration of the juice, seed oil, and peel extract is still believed to be true. In this review, target components of pomegranate such as antioxidants, anticancers, antiestrogens and ethnomedical components were analyzed and discussed along with examining its pharmaceutical efficacy and prescription to postmenopausal lesion, cardiosclerosis, cosmetic beautification, viral and allergic symptoms, and diabetes mellitus, etc.

• 식물병연구
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• 제9권1호
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• pp.18-20
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• 2003

경상북도농업기술원에 정원수로 심어져 있는 석류나무 (Punica granatum)에서 잎의 황화와 가지의 고사현상과 더불어 가지표면에 혹이 발생하는 것을 채집하였다. 이혹에서 Botryosphaeria dothidea균이 분리되었으며, 분리된 균을 석류나무 가지에 재접종하였을 때 병원성이 확인되었고, 자연발생된 병징과 동일한 병징을 나타내었다. 우리나라에서 Botryosphaeria dothidea에 의한 석류나무 줄기썩음병(가칭)으로 최초 보고한다.

• 동의생리병리학회지
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• 제21권1호
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• pp.199-203
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• 2007

Dental caries is a major worldwide oral disease problem. Streptococcus mutans (S. mutans) plays an important role in the information of dental plaque and it is being noticed as major causative bacteria of dental caries. Therefore, the development of more effective, substantial and safe preventive agents against dental caries is strongly required. In the present study, inhibitory effects of the ethanol extract of the husk of pomegranate (Punica granatum L.) on the growth, acid production, adhesion and water-insoluble glucan synthesis of Streptococcus mutans (S. mutans) were examined. The ethanol extract of pomegranate husk (250 - 4000 ${\mu}$g/ml) significantly lowered the growth of S. mutans in a dose dependent manner. The acid production of S. mutans were inhibited by the presence of ethanol extract of pomegranate husk (500 - 4000 ${\mu}$g/ml) significantly. The ethanol extract of pomegranate husk (5000 - 4000 ${\mu}$g/ml) also significantly lowered the adherence of S. mutans. In water-insoluble glucan synthesis assay, 1000 - 4000 ${\mu}$g/ml of the ethanol extract of pomegranate husk significantly inhibited the formation of water-insoluble glucan. These results suggest that pomegranate husk may inhibit the caries-inducing properties of S. mutans. Further studies are necessary to clarify the active constituents of pomegranate husk responsible for such biomolecular activities.

• 한국염색가공학회:학술대회논문집
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• 한국염색가공학회 2012년도 제46차 학술발표회
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• pp.55-55
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• 2012

To improve the deodorizing and antibacterial performance of various fabrics (cotton, silk and wool) dyed with pomegranate(Punica granatum L.) extract without mordants, natural colorant solutions, which were extracted from pomegranate using water as an extractant at $90^{\circ}C$ for 90 min with a various liquor ratio (solid natural colorant material/solvent water, weight ratio) from 1:100 to 1:5 were used. To achieve the highest K/S and the deodorizing and antibacterial performance, the best liquor ratio, dyeing bath ratio, dyeing temperature and dyeing time were found to be 1:10, 1:50, $80^{\circ}C$ and 60 min, respectively. The deodorizing performance of dyed cotton, silk and wool fabrics against acetic acid vapor were found to be95,70,90%,respectively. However, all the dyed fabrics displayed outstanding deodorizing performance(99%) against ammonia gas and antibacterial performance(bacteriostatic reduction rate:99.9%) against Staphylococcu aureus and Klebsiella pneumonia(bacteriostatic reduction rate: 99.9%). It is worth noting that pomegranate (Punica granatum L.) colorants notably enhanced the deodorizing and antibacterial performance of cotton, silk and wool fabrics.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.19-19
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• 2001

Pomegranate (Punica granatum) is one of the worlds most ancient fruits, and also one of the most botanically isolated, comprising a single family (Punicae) with its rare relative, Punica protopunica, a species limited in occurrence to the island of Socotra off the coast of Yemen. Pomegranate, though, is extremely well known, flourishes in many parts of the world, is traditionally prized for its medicinal properties and widely regarded as Symbol: of fecundity, longevity, spirituality and Medicine.(omitted)

• Restorative Dentistry and Endodontics
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• 제49권1호
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• pp.9.1-9.14
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• 2024

Objectives: This study aimed to evaluate the effect of pomegranate solution (Punica granatum) on eroded dentin through antioxidant action, shear bond strength (SBS) and interface morphology. Materials and Methods: The 10% pomegranate peel extract was prepared by the lyophilization method. Punicalagin polyphenol was confirmed by high-performance liquid chromatography. Antioxidant activity was evaluated by capturing the 2,2-diphenyl1-picrylhydrazyl (DPPH) radical. For the SBS, 48 dentin fragments were divided into sound or eroded, and subdivided according to the pretreatment (n = 12): water or P. granatum. The surfaces were restored with self-etch adhesive and a bulk-fill resin (Ecosite; DMG). The SBS was done immediately (24 hours) and after thermal cycling + water storage (12 months). For scanning electron microscopy, 48 dentin fragments (24 sound and 24 eroded) received the same treatments as for SBS (n = 6), and they were analyzed after 24 hours and 12 months. Results: The P. granatum had antioxidant action similar (p = 0.246) to the phenolic standard antioxidants. After 24 hours, eroded dentin had lower SBS than sound dentin (p < 0.001), regardless of the pretreatment. After 12 months, P. granatum maintained the SBS of sound dentin (13.46 ± 3.42 MPa) and eroded dentin (10.96 ± 1.90 MPa) statistically similar. The lowest values were found on eroded dentin treated with water (5.75 ± 1.65 MPa) (p < 0.001). P. granatum on eroded dentin caused peritubular demineralization and hybrid layer with resin tags. Conclusions: The pomegranate extract had antioxidant action and preserved the adhesive interface of the eroded dentin.

• 식물병연구
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• 제8권4호
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• pp.215-219
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• 2002

2002년 7월 경남 통영시 광도면 석류재배 농가포장에서 열매가 부패되는 이상증상이 발생하였다. 분리된 병원균은 감자한천배지에서 균총의 색깔은 흰색이며 물결모양을 이루면서 왕성하게 자랐고, 배지상에서 분생포자각을 잘 형성하였다. 분생포자는 단세포이며 모양은 방추형이고, 색깔은 갈색 또는 올리브색이다. 크기는 10.3~17.4$\times$2.8~4.0 $\mu\textrm{m}$ 였다. 분생포자 형성 세포는 짧은 원통형이며 무색으로 크기는 12.4~1.4$\times$2.8~3.6 $\mu\textrm{m}$ 였다. 불생포자각의 모양은 구형이며 갈색으로, 각벽은 2~3세포이고, 크기는 124.6~228.4 $\mu\textrm{m}$ 였다. 균사생육 적온은 $25^{\circ}C$였다. 분리된 병원균을 건전한 석류에 유상, 무상접종한 결과 접종 3일 후 감염을 일으켰으며, 병원성이 강하였다. 이상과 같이 이 병원균을 Coniella granati에 의한 석류열매 썩음병으로 명명할 것을 제안한다.

• Horticulture, Environment, and Biotechnology : HEB
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• 제59권6호
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• pp.857-864
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• 2018

Previous studies have not detected transcripts of the gene encoding anthocyanidin synthase (ANS) in white pomegranates (Punica granatum L.) and suggest that a large-sized insertion in the coding region of the ANS gene might be the causal mutation. To elucidate the identity of the putative insertion, 3887-bp 5' and 3392-bp 3' partial sequences of the insertion site were obtained by genome walking and a gene coding for an expansin-like protein was identified in these genome-walked sequences. An identical protein (GenBank accession OWM71963) isolated from pomegranate was identified from BLAST search. Based on information of OWM71963, a 5.8-Mb scaffold sequence with genes coding for the expansin-like protein and ANS were identified. The scaffold sequence assembled from a red pomegranate cultivar also contained all genome-walked sequences. Analysis of positions and orientations of these genes and genome-walked sequences revealed that the 27,786-bp region, including the 88-bp 5' partial sequences of the ANS gene, might be translocated into an approximately 22-kb upstream region in an inverted orientation. Borders of the translocated region were confirmed by PCR amplification and sequencing. Based on the translocation mutation, a simple PCR codominant marker was developed for efficient genotyping of the ANS gene. This molecular marker could serve as a useful tool for selecting desirable plants at young seedling stages in pomegranate breeding programs.

• 한국식품영양학회지
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• 제30권3호
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• pp.578-590
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• 2017

An agricultural waste, pomegranate (Punica granatum L.) peel is known to be rich in total phenolics, which are flavonoids having strong antioxidant effects. In this study, pomegranate peel sponge cakes were prepared with varying ratios of freeze dried pomegranate peel powder (0, 1, 3, 5, 7% (w/w)) to examine their effect on quality characteristics, retrogradation and antioxidant activities. The specific gravity and moisture contents of 3, 5, and 7% pomegranate peel powder showed higher values than the control and 1% group. Addition of pomegranate peel powder increased the batter yield, while there was a significant decrease in baking loss. Increasing pomegranate peel powder content significantly decreased the lightness (L) (from 75.03 to 57.04) and pH values, whereas redness (a), yellowness (b) and ${\Delta}E$ were increased. Increasing concentration of the peel powder also increased the hardness and chewiness, while the springiness and cohesiveness decreased. Considering the Avrami equation, Avrami exponene (n) decreased from 1.8055 (control) to 0.9199 (7% pomegranate peel powder). Time constant (1/k) was lowest in control (at 17.64) and highest in the 7% group (39.84). Total polyphenol, flavonoid content, DPPH and ABTS radical scavenging activities significantly increased with increments in the content of pomegranate peel powder. A sensory evaluation by the 7-point scaling method showed that the sponge cake containing 7% pomegranate peel powder had the highest scores in color, flavor, sweetness, chewiness and overall acceptability. Hence, it is considered that sponge cake supplemented with 7% pomegranate peel powder is the most appropriate for quality characteristics, retrogradation and antioxidant activities.

• 한국식품과학회지
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• 제44권4호
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• pp.417-421
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• 2012

최근 막걸리 소비량이 증가함에 따라 막걸리의 기능성 및 기호도가 증진되고 있어 막걸리에 석류의 기능성을 부여하고 색택을 향상시키고자 석류즙 농축액을 이용하여 석류 막걸리를 제조하였다. 막걸리 제조를 위해 첨가 시기 및 농축액 첨가량(3, 5, 7%)을 달리하여 석류 막걸리를 제조하였으며, 제조된 석류즙 막걸리의 이화학적 특성 및 관능평가를 실시하였다. 그 결과 석류즙 농축액 첨가량이 많을수록 적정산도, 당도, 알코올 함량은 높았다. 반대로 pH 아미노산 함량은 첨가량이 많을수록 낮았으며, 석류 막걸리의 관능검사 결과 3% 석류즙 농축액을 첨가한 처리구가 단맛, 신맛, 쓴맛, 향, 색감, 전체적 기호도에서 가장 높은 점수를 얻었으며 석류즙 막걸리를 위한 밑술 제조 시 3% 석류즙 농축액을 첨가하여 제조한 막걸리의 품질이 가장 우수하였다. 결과를 종합해 볼 때, 석류즙 농축액 3%를 밑술 제조 시 첨가하여 제조하는 것이 석류 막걸리의 제조와 제조된 석류 막걸리 제품화에 있어서 가장 우수할 것으로 판단된다.