• 한국식품영양학회지
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• 제35권2호
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• pp.116-126
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• 2022

The purpose of this study was to analyze the anti-inflammatory effect of Chung-Dae Indigo Pulverata Levis, indigo naturalis) produced during indigo dyeing. As a result of in vitro cytotoxicity experiments using RAW 264.7 cell, Chung-Dae extract did not inhibit cell proliferation in Raw 264.7 cells in the range of 1~32 ㎍/mL. NO production was significantly reduced when Chung-Dae extracts were treated at concentrations of 2, 8, and 32 ㎍/mL (p<0.05). The pro-inflammatory cytokines TNF-α, IL-6, IL-1β and IFN-γ significantly decreased when the Chung-Dae extract was treated at concentrations of 2, 8, and 32 ㎍/mL compared to the LPS group, and similarly, the TNFα and IL-6 mRNA levels also decreased. Additionally, the mRNA level of COX-2 was also suppressed. At the protein expression level, the expression of TNF-α, IL-6, iNOS and COX-2 were observed with LPS and Chung-Dae extract significantly decreased compared to the group treated with only LPS (p<0.05). From the above results, it shows that Chung-Dae extract, a plant-derived compound, inhibits the inflammatory response induced by LPS in RAW 264.7 cells. and in particular, regulates the inflammatory response by inhibiting the expression of pro-inflammatory cytokines and inflammation-related enzymes.

• 한국의상디자인학회지
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• 제4권3호
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• pp.9-15
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• 2002

Compared with synthetic dyes, natural dyes have inferior colorfastness as a result of the exposure of the material to any environment that may be encountered during the processing, testing, storage, display or use of the dyed materials. Especially, colors on fabrics fade excessively after washing. Therefore, it is problem to infer the historic textiles with natural-dyed fabrics. The object of this study is to analyse the factors affected to colorfastness and color change during washing. In experimental, fifteen natural dyes were dyed by the Korean traditional dyeing methods onto natural fiber fabrics: cotton, silk, ramie, and flex. Total 49 dyed fabrics in combination with dyes and fibers were used for the specimen. The Launder-Ometer was used for evaluating the effects of exposure to repetitive washing from 1 to 20 washing cycles (KS K 0430). Color difference(ΔE) in the CIEL＊A＊B＊ color-order system were determined by spectrophotometer at 100 bserver. Washing caused significant changes in the color of natural-dyed fabrics. The degree and nature of color changes on the fabrics were dependent on the combination of fiber and the dye type used. The groups of violet(Lithospermum erythrorhizon Sieb.et Zucc) and black color(Ailanthus altissima Swingle, Phus trichocarpa Miq) yielded excellent colorfastness to repetitive washing. The group of indigo blue color(Polygonum tinctorium Lour.) was also very resistant to color change in washing except silk. Whereas the dye groups of Red, Yellow, Orange, Brown colors indicated greatest changes in color, particularly Carthamus tinctorius L.

• 한국의상디자인학회지
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• 제6권3호
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• pp.45-53
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• 2004

Natural dyes have poor colorfastness as a result of the exposure of the dyed fabric to sunlight encountered during the display or wearing. As colors on fabrics fade excessively under sunlight, it is a problem to infer and restore the historic textiles with natural-dyed fabrics to original colors. The object of this study is to analyse the factors affected to color change under light. In experimental, fifteen natural dyes were dyed by the Korean traditional dyeing methods onto natural fiber fabrics: cotton, silk, ramie, and flex. Total 49 dyed fabrics in combination with dyes and fibers were used for the specimen. The Weather-O-meter was used for evaluating the effects of exposure to light for 2.5 to 450 hours. The process of color changes in the CIEL *A*B* color-order system to the exposure time were determined by spectrophotometer at 10$^{\circ}$ observer. Sunlight exposure caused significant changes in the color of natural-dyed fabrics. The degree and nature of color changes on the fabrics were dependent on the combination of fiber and the type of dye used. The groups of violet(Lithospermum erythrorhizon Sieb.et Zucc.) and black color(Ailanthus altissima Swingle, Phus trichocarpa Miq) yielded excellent colorfastness to light. The group of indigo blue color(Polygonum tinctorium Lour.) was also very resistant to fading in both exposure except silk. Whereas the dye groups of Red, Yellow, Orange, Brown colors indicated greatest changes in fading, particularly Carthamus tinctorius L.