• Title/Summary/Keyword: Poisonous drug

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체질간호 이론 정립을 위한 연구 II - "동의수세보원 갑오구본"을 중심으로- (A Study about Construction of Sasang Constitutional Nursing Theory II - On the Focus of ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$written in 1894 (Old Edition) -)

  • 유정희;안상우;이의주;송일병;고병희
    • 사상체질의학회지
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    • 제18권1호
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    • pp.41-53
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    • 2006
  • 1. Objectives Nursing's meaning in Oriental medicine is prevention of disease more than treatment. The parts of defination are methods of non-medicine precisely, care of health and recuperation. 2. Methods This paper was written in order to understand of ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$ written in 1894(Old Edition} through the study to focus on the Sasang Constitutional nursing theory. 3. Results & Conclusions (1) Dialectic of Sasang Constitutional nursing are necessary to assesment about four fundamental factors (perspira­tion, defecation, digestion, urination). (2) Medicational guidance are different from character, dosage of medication, degree of disease, a poisonous drug etc. (3) Preservation of health are medication and food regimen. If 'Inherent vitality' is in a disadvantageous position, recuperation is first more than medication. The most important is protectional management. There are necessary about mind of 'liquor-sex- property-authority' & 'joy-anger- sorrow-pleasure'. It is the same application as nursing.

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상백피(桑白皮)에 관한 연구(硏究)(I) -상백피(桑白皮)의 본초서지학적(本草書誌學的) 분석(分析)- (Studies on Root Bark of Mulberry Tree (I) -Bibliographical Analysis on Mori Cortex Radicis in Herbal and Formularies)

  • 류경수;안덕균
    • 생약학회지
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    • 제11권2호
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    • pp.85-94
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    • 1980
  • In this paper, we studied what the drug name of Sang-Baik-Pi(桑白皮) Mori Cortex Radicis) is, how to collect it; and how the chief symptoms had changed in the chinese medical references and herbological literatures and formularies. Also we bibliographically analyzed in the herbological way the drugs combinated with Sang-Baik-Pi and their active principles among the prescriptions in the famous medical book; 'Dong-Ui-Bo-Gam', (東醫寶鑑) of our country. Finally, we concluded as foolow. Numerous names of botainical origin were described, but it was not recorded that San-Keun-Baik-Pi(桑根白皮) in old days is different from root bark of Morus sp. in this times. Sang-Baik-Pi has been a common designation since Ming dynasty (AD 1500). Collections of it were independent of seasons, it could effect perfectly over 10 years old. And its cork layer should be removed after collections, it was especially emphacised that root bark on ground was poisonous. The chiefly cured symptoms with Sang-Baik-Pi were constantly not different from the contents of 'Shin-Nong-Bon-Chau-Kyung'(神農本草經) in ancient times, but it has been developed since Ming dynasty. Its uses are widely extended to a surgical and dermatologic desease; rheumatis, beriberi and diabetes in this times. and its efficacies depend upon curing. Prescriptions on Sang-Baik-Pi that were prescribed in 'Dong-Ui-Bo-Gam' are there, 177 drugs combinated with it. Glycyrrhizae Radix is most frequently combinated with Sang-Baik-Pi(frequently 68%). It is proved that Armeniacae Semen, Platycodi Radix etc, in the order take strong effects on anti-tussive, anti-phlogistic, diuretic, anti-pyretic etc. It is expressed 34 times, frequently, that a dose is 3.75g, and it shows that a usual doses is 2-4g. As the above prescriptions are classified, the results is as follows, respiratory tract desease is most frequently in 69 prescriptions, the next gastrointestinal tract 13 times, diuretic 12 times, and antipyretic 11 times. Therefore, Sang-Baik-Pi contains a good remedial value chiefly of the effects upon the respiratory diseases.

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노인 중독 환자의 특성 (Characteristics of elderly patients with acute poisoning)

  • 김보경;정시영;정구영
    • 대한임상독성학회지
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    • 제8권2호
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    • pp.61-68
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    • 2010
  • Purpose: Poisoning is a major health problem for the elderly, and poisoning can cause fatal side effects. However, the characteristics and clinical features of elderly patients with acute poisoning have not been well studied in the previous domestic research. So, we tried to analyze the clinical characteristics and toxic substances of the patients who were 65 years old or older and who were admitted to the regional emergency medical center due to acute poisoning. Methods: We retrospectively reviewed the medical records and poisoning protocols of the patients who were 65 years of age or older and who had with acute poisoning and who visited the ED in our emergency center from January 2005 to December 2009. We collected the demographic information, the gender, the underlying diseases, the causes and toxic substances, the initial presentation, the treatment and the outcomes. Results: A total of 2179 poisoned patients visited the hospital during 5 years, and among them 244 were 65 years of age or older (11.2%). The mean age was $75.6{\pm}6.9$ years and the male:female ratio was 1:1.7. The most common cause of poisoning was suicide (73.4%) and the most common source of poisonous substances was their own drugs. Of the substances used for poisoning, benzodiazepine was the most common drug (25.8%), followed by sedatives other than benzodiazepine (25.4%), insecticide (12.7%), chemical agents (12.3%) and herbicides (8.2%). The most common initial presentation was mental change (64.8%). When comparing the factors between the three elderly groups, there was no difference in gender, the cause, the substances and the underlying disease. The outcomes of treatment included ICU admission (56.1%), a good condition at discharge (12.7%) and admission to a general ward (12.7%). The overall mortality rate was 10.2% for the elderly patients. Conclusion: In this Korean study, unlike the foreign studies, the most common cause of poisoning in elderly patients was intentional poisoning. The admission rate was 68.8% and mortality rate was 10.2%.

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낭탕근(狼菪根) 중독 환자의 가미감두탕(加味甘豆湯) 투여 증례 1례 (The Case of Toxicity Caused by Scopolia Japonica Ingestion Treated with Gamigamdu-Tang.)

  • 이혜윤;조수인;박혜림;조민경;이인;홍진우;권정남
    • 대한중풍순환신경학회지
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    • 제15권1호
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    • pp.50-56
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    • 2014
  • The prevalence rate of plant poisoning is growing up gradually. However, it could be difficult to get proper treatment without detail medical history taking due to the diversity of poisonous plants and their various symptoms. Scopolia Japonica, which grows naturally in Korea, is reported to cause severe toxicity which could be lethal. A few therapeutic measures have been reported in Traditional Korean Medicine (TKM), but it has not been reported yet that those measures have been successfully proven in the clinical practice in modern times. This is a case report of toxicity caused by scopolia japonica ingestion. A 65years-old male patient with cognitive impairment, behavioral disorder, gait difficulty, dysarthria, dysphagia and abnormal pupil reflex recovered from those symptoms during taking Gamigamdu-tang and getting acupuncture. This study shows the clinical aspects of Scopolia Japonica toxicity and the possibility of TKM treatments as one of plant poisoning treatments.

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Tox-Info 시스템의 중독정보 데이터베이스와 응급실에 내원하는 중독 환자 분포의 비교 (Comparison between Emergency Patient Poisoning Cases and the Tox-Info System Database)

  • 김현종;김양원;김현;박창배;소병학;이경룡;이경우;이경원;이성우;이장영;조규종;조준호;정성필
    • 대한임상독성학회지
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    • 제10권1호
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    • pp.8-14
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    • 2012
  • Purpose: The Tox-Info system is a poisonous substance information database developed by the Korean National Institute of Food and Drug Safety Evaluation. The aim of this study was to estimate the coverage effectiveness of the Tox-Info system by comparing the toxic substances included in the database with the distribution of the toxic substances implicated in the cases of intoxicated patients presenting to emergency departments. The secondary aim of the study was to propose any additional substances that should be added to the database. Methods: We retrospectively reviewed the medical records of patients suffering with toxic exposure who had visited any of 12 selected emergency departments in Korea from January 2010 to December 2011. The identified toxic substances were classified into groups including prescription drugs, agricultural chemicals, household products, animals or plants, herbal drugs, and others. We calculated the coverage rate of the Tox-Info database relative to the number of intoxication cases and the type of toxic substances involved. Results: A total of 5,840 intoxicated patient records were collected. Their mean age was $46.6{\pm}20.5$ years and 56.2% were female. Of the total intoxication cases, 87.8% of the identified toxic substances were included in the Tox-Info database, while only 41.6% of all of the types of identified toxic substances were included. Broken down by category, 122 prescription drugs, 15 agricultural chemicals, 12 household products, 14 animals or plants and 2 herbal drugs involved in poisoning cases were not included in the Tox-info database. Conclusion: This study demonstrated the clinical usefulness of the Tox-Info system. While 87.8% of the substances involved in the cases were included in the Tox-Info database, the database should be continuously updated in order to include even the most uncommon toxic substances.

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급성 중독으로 응급실에 내원하여 사망한 환자의 원인물질 및 시간 분포 (Causative Substance and Time of Mortality Presented to Emergency Department Following Acute Poisoning: 2014-2018 National Emergency Department Information System (NEDIS))

  • 이현재;좌민홍;한은아;고동률;고재욱;공태영;조준호;정성필
    • 대한임상독성학회지
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    • 제19권2호
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    • pp.65-71
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    • 2021
  • Purpose: The purpose of this study was to investigate the cause of acute fatal poisoning and the time of death by analyzing the National Emergency Department Information System (NEDIS) of South Korea. Methods: The NEDIS data from 2014 to 2018 excluding non-medical visits were used for this study. The patients with acute poisoning were extracted using diagnostic codes. The toxic substances were classified into pharmaceuticals, pesticides, gases, artificial poisonous substances, and natural toxic substances. Patients were classified according to the time of death, place of death, and region. In each case, the most causative substances of poisoning were identified. Results: There were 380,531 patients including poisoning-related diagnoses, of which 4,148 (1.1%) died, and the WHO age-standardized mortality rate was 4.8 per 100,000. Analysis of 2,702 death patients whose primary diagnosis was acute poisoning, the most common cause of poisoning death was pesticides (62%), followed by therapeutic drugs, gas, and artificial toxic substances. Herbicides were the most common pesticides at 64.5%. The proportion of mortality by time, hyperacute (<6 h) 27.9%, acute (6-24 h) 32.6%, subacute (1-7 d) 29.7%, and delayed period (>7 d) were 9.8%. Conclusion: This study suggests that the most common cause of poisoning death was pesticides, and 60% of deaths occurred within 24 hours. The 71% of mortality from pesticides occurred within 6-24 hours, but mortality from gas was mostly within 6 hours. According to the geographic region, the primary cause of poisoning death was varied to pesticides or pharmaceuticals.