• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.27 no.3
• /
• pp.416-423
• /
• 2003

During the last ten years, the need has been increased for reducing maintenance cost for aged equipments and ensuring safety, efficiency and profitability of petrochemical and refinery plants. RBI (Risk Based Inspection) methodology is one of the most promising technologies satisfying the need in the field of integrity management. In this study, a user-friendly software, realRBl for RBI based on the API 581 code was developed. This software has modules for evaluating qualitative and semi-quantitative risk level, analyzing quantitative risks using the potential consequences of a failure of the pressure boundary, and assessing the likelihood of failure. A quantitative analysis was performed for 16 columns in a domestic NCC (Naphtha Cracking Center) plant whose operating time reaches about 12 years. Each column was considered as two equipment parts by dividing into top and bottom. Generic column failure frequencies were adjusted based on likelihood data. After determining release rate, release duration and release mass for each failure scenario, flammable/explosive and toxic consequences were assessed. Current risks for 32 equipment parts were evaluated and risk based prioritization were determined as a final result.

• Bulletin of the Korean Chemical Society
• /
• v.33 no.5
• /
• pp.1707-1714
• /
• 2012

Grb2 is an adapter protein involved in the signal transduction and cell communication. The Grb2 is responsible for initiation of kinase signaling by Ras activation which leads to the modification in transcription. Ligand based pharmacophore approach was applied to built the suitable pharmacophore model for Grb2. The best pharmacophore model was selected based on the statistical values and then validated by Fischer's randomization method and test set. Hypo1 was selected as a best pharmacophore model based on its statistical values like high cost difference (182.22), lowest RMSD (1.273), and total cost (80.68). It contains four chemical features, one hydrogen bond acceptor (HBA), two hydrophobic (HY), and one ring aromatic (RA). Fischer's randomization results also shows that Hypo1 have a 95% significant level. The correlation coefficient of test set was 0.97 which was close to the training set value (0.94). Thus Hypo1 was used for virtual screening to find the potent inhibitors from various chemical databases. The screened compounds were filtered by Lipinski's rule of five, ADMET and subjected to molecular docking studies. Totally, 11 compounds were selected as a best potent leads from docking studies based on the consensus scoring function and critical interactions with the amino acids in Grb2 active site.

• Journal of the Korean Society of Safety
• /
• v.21 no.5 s.77
• /
• pp.53-59
• /
• 2006

Standard safety management costs can not be applied to each site with same rate, it is very difficult, because it depends on the experience, work method, work kind, work progress schedule, and hazard level of each construction company. Therefore, this study is to find out hazard level of each work kinds through questionnaire and interview and investigate analyze the status which standard safety management costs have been used. Also, this study is to show reasonable rates of standard safety management costs in construction industry and to set up countermeasures against those problem after reviewing its status in korea with in Japan and Europe. The domestic system of standard safety management costs is not considered in the foreign country, while only related subjective items have been investigated and evaluated for this study. This study is to investigate eleven project kinds of domestic system, first, and to investigate eleven items of apartment bldg, office, civil work such as bridge, tunnel, dam, plant etc, secondly. Additionally, three items of gymnasium, railway, particular steel tower are investigated in this study. Also this study is to investigate and analyze performed costs of presently processing worker finished work so that it shows a new reasonable rate against standard safety management costs in construction industry, in order to make basial data and material to be systemized.

• Journal of Environmental Health Sciences
• /
• v.43 no.5
• /
• pp.431-437
• /
• 2017

Objectives: To protect the health and safety of residents during chemical accidents, the governmental authorities need to provide personal protective equipment (PPE) to citizens who desire it. This study aims to investigate residents'awareness of PPE and perform an economic analysis on providing PPE to residents near chemical plants prior to the establishment of a related law. Methods: This study was carried out through a questionnaire completed by 600 residents composed of items such as residents'awareness of PPE, what type of PPE they need, and how to purchase PPE. Economic analysis (cost-benefit analysis) was conducted on providing PPE to residents near chemical plants on basis of the Gumi City hydrogen fluoride accident of 2012. Results: The results of the questionnaire showed that most residents recognized the need for PPE preparedness for chemical accidents, in particular, for respirators. The level of expense that respondents were prepared to shoulder to share the burden was $25. Except for chemicals of hazard level 2, the benefit of all kinds of chemical accident preparedness considerably exceeded costs in the cost-benefit analysis on providing PPE. An estimated government budget of $20 million per year would be required to provide PPE (hood-type mask) for all residents within a one-kilometer radius of chemical plants in Korea, but only $5.8 million when residents share the expenses. Conclusion: The results of this study suggest that programs for providing PPE for residents near chemical plants should be established by law.

• Korean Journal of Microbiology
• /
• v.46 no.1
• /
• pp.33-37
• /
• 2010

Rhizobacterial strain isolated from barren soil, Bacillus subtilis RFO41 exhibits a high level of phosphate solubilizing activity and produces some phytohormones. Its promoting effect on the growth of Xanthium italicum Moore, a wild plant growing at lakeside barren land and thus a good candidate plant for revegetation of barren lakeside was evaluated in the in situ test for 19 weeks at Lake Paro, Kangwon-do. Strain RFO41 could enhance the dry weight of X. italicum by 67.7%. It also increased the shoot length of X. italicum plant by 21.1% compared to that of uninoculated control. Both growth enhancements had statistical significance. However, the inoculation did not show any effect on the root growth, which might be due to the breakage of tiny root. Denaturing gradient gel electrophoresis analysis showed that the inoculated bacteria were maintained in the soils, and the indigenous bacterial community did not exhibit any significant change. This plant growth promoting capability may be utilized as an environment-friendly and low cost revegetation method, especially for the sensitive areas such as barren lakeside lands.

• Journal of Digital Convergence
• /
• v.16 no.12
• /
• pp.123-135
• /
• 2018

The objective of this paper is to investigate the issues related to the supply chain management in plant engineering industry, and propose the framework to improve the project efficiency. The preliminary case study shows that EPC's fragmented nature, lack of coordination and information sharing, and lack of proper risk and change management contribute to project delay and cost overrun. To examine the level of informatization and information sharing in supply chain, survey responses from the suppliers and subcontractors have been collected. The statistical results show that information sharing, early involvement in design process and awareness in SCM have influenced the level of collaboration, but supplier assessment and informatization have no impact on the collaboration. A conceptual model is proposed in order to facilitate the integration of design, procurement and construction functions. Implications from the study are also provided.

• Korean Journal of Organic Agriculture
• /
• v.1
• /
• pp.19-28
• /
• 1992

The definitions of organic farming method has rather philosophical meaning than application of agricultural practices. The meaning of organic farming method has certainly basic differences in comparison with the conventional farming methods. The main definitions of organec farming method have certainly to reduce or not to apply any kinds of farm inputs materials by increasing quality of agricultural prod-ucts. However, the quality of produced food by organic farming method should be improved in compari-son with cinvethional farming method. By applying organic method, the qualith of food, envir-onment as well as spiritual attitude of human being should be improved in future. Actually, there are very wide fields of research on organic farming methods such as production tech-niques, soil and water conservation, plant and animal production, marketing and consumers behavior on organic products. In this article the present situation of organic farming methods in the United States of Americal is investigated in cimparison with conventional rice production. The production cost of rice per acre in the United States of America mde 58, 788 Won in 1986, while it was 121, 699 Won in Korea having about 107 percent higher in Korea than tham the U.S.A There is a larger rice farm cost analysis between conventional and organic rice farm in California. The cash cost pre 1 lbs of conventional rice made 4.86 $, while the organic rice was 6.96$ showing about 43.2%higher level of cost in organic products(1 lbs=0.45359kg) At present, there is less econmic advantage of organic rice production in California because of lower yields as well as price levels, Therefore, the total net return over cash cost peracer/yeat was a little lower in organic rice production than conventional rice prouction.

• Korean Journal of Medicinal Crop Science
• /
• v.15 no.2
• /
• pp.95-99
• /
• 2007

The cost of conventional cultivation of ginseng (Panax ginseng C.A. Meyer) is very expensive, because shadow condition should be maintained during cultivation periods owing to inherently weak plant for high-temperature. Therefore, application of plant biotechnology may be possible to overcome these difficulties caused by conventional breeding of ginseng. Transgenic plants were produced via Agrobacterium tumefaciens Gv3101, both carrying the binary plasmid pBI121 mLPISO with nptII and Iso (isoprene synthase) gene. Integration of the transgenes into the P. ginseng nuclear genome was confirmed by PCR analysis using nptII primers and Iso primers. RT-PCR result also demonstrated the foreign isoprene synthase gene in three transgenic plant lines (T1, T3, and T5) which was expressed at the transcriptional level. When whole plants of transgenic ginseng were exposed to high temperature at $46^{\circ}C$ for 1 h, a non-transformed plant was wilted from heat shock, whereas a transgenic plant appeared to remain healthy. We suggest that the introduction of exogenous isoprene synthase is considered as alternative methods far generating thermotolerance ginseng.

• KEPCO Journal on Electric Power and Energy
• /
• v.7 no.2
• /
• pp.277-283
• /
• 2021

Power plant simulators have been used for operator training, control verification and engineering verification. In general, simulators can be used in the place where they are installed by only single user group at a time. Considering high cost of simulator development, a lot of available scenarios, the diversity of user level and accessibility based on users' work location, development of simulator system that can be used by multiple user groups regardless of location is required in order to enhance utilization of simulators. In this paper, the simulator system that can be used by multiple user group simultaneously without location limitation is proposed. The simulator system is composed of simulator servers, database servers, HMI servers, a web server, web clients. Simulator server consists of control model, process model that are developed for Circulating Fluidized Bed power plant located overseas. A web server manages user accounts, operation procedures, multiple server access between web client group and simulator server group. In other words, a web server makes a user group select a simulator server at a time. The developed simulator system is integrated after implementing process model, control model, HMI, and web server. Web client systems are installed on local site where power plant is located, while simulator servers, HMI servers, database servers, and a web server are located in KEPCO RI. The developed simulator system is verified by steady-state test, malfunction test and so on via remote access.

• Journal of Korean Institute of Industrial Engineers
• /
• v.1 no.1
• /
• pp.41-56
• /
• 1975

In the past the pattern of business down-trend usually appeared in the form of, first, decrease in facility investment, then decrease in inventory level, followed by reduced level of consumption. But the pattern nowadays is becoming just the opposite, that is, first, consumption decrease, then inventory level increase, followed by restriction of facility investment. Also in the past, the greater effort was placed in strengthening of hardware areas through optimization and modernization of production means on the premise of sales. But lately software areas take most of the main effort to establish production mean with sales as its objective. Under these circumstances one of the real problems facing production activities today is the conflicting relationship between sales and production functions. This occurs due to differences of their view points. Then, in order to achieve maximum profit at the least cost, which is the ultimate objective of a production activity, the need arises to effectively coordinate sales demand and plant production capacity. For this purpose strong control means and function must be devised. In our case study example we illustrate a management technique for a combined planning function, of optimal coordination of product mixes utilizing a computerized linear programming model as control means of attaining maximum profit. It is hoped that this example help achieve some of corporate objectives.