• 한국콘텐츠학회논문지
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• 제18권12호
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• pp.489-502
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• 2018

중국 도시재생 과정 속에서 정부, 기업, 시민, 전문가들 간의 대화와 상호작용을 강화하는 것이 필요하다는 것에서 시작되었다. 중국 도시재생이론의 대부분은 거시적 차원의 정책에만 머물러 있어, 참여주체의 소통을 세부적으로 분석하여 도시재생문제를 해결하고자 하는 연구의 수는 매우 부족한 현실이다. 그래서 본 연구는 사례분석과 설문조사를 통해 중국 도시재생의 의사소통에 관한 평가하고자 한다. 도시재생 사례에서 나타난 소통 요소를 분석하며, 그에 따른 연구 분석사례의 범위로는 2000년 이후 최근 중국 도시재생 사례분석과 전문가 설문조사를 병행 하였다. 본 논문의 연구결과인 도시재생 평가모델은 중국 현 단계의 국가운영에 적합하며, 현재 중국이 응용가능한 도시재생모형이라고 판단된다.

• 대한치과교정학회지
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• 제49권4호
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• pp.222-234
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• 2019

Objective: To investigate the three-dimensional lip vermilion changes after extraction and non-extraction orthodontic treatment in female adult patients and explore the correlation between lip vermilion changes and incisor changes. Methods: Forty-seven young female adult patients were enrolled in this study (skeletal Class III patients were excluded), including 34 lip-protruding patients treated by extraction of four first premolars (18 patients requiring mini-implants for maximum anchorage control and 16 patients without mini-implants) and 13 patients requiring non-extraction treatment. Nine angles, seven distances, and the surface area of the lip vermilion were measured by using pre- and post-treatment three-dimensional facial scans. Linear and angular measurements of incisors were performed on lateral cephalograms. Results: There were no significant changes in the vermilion measurements in the non-extraction group. The vermilion angle, vermilion height, central bow angle, height/width ratio, and vermilion surface area decreased significantly after the orthodontic treatment in the extraction groups, but the upper/lower vermilion proportion remained unchanged. Significant correlations were found between the changes in incisor position and those in vermilion angles, vermilion height, and surface area. Conclusions: Extraction of the four first premolars probably produced an aesthetic improvement in lip vermilion morphology. However, the upper/lower vermilion proportion remained unchanged. The variations in the vermilion were closely related to incisor changes, especially the upper incisor inclination changes.

• 한국콘텐츠학회논문지
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• 제19권6호
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• pp.236-248
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• 2019

수도권의 그린벨트는 도시 경계선을 설치하여 생태 보호체계를 구축하고 도시의 탄성을 강화하는 데 목적이 있다. 베이징시에서 현재 진행되고 있는 도시종합계획이 실시되는 기한 동안 두 그린벨트가 포함하는 지역의 녹색 공간은 변화에 따라 그 비율에 큰 차이가 존재한다. 본 연구는 이를 출발점으로 삼아 '도시 구조체계요소' 및 '정책과 계획요소'가 녹색 공간 규모의 변화와 갖는 상관성을 연구하여, 베이징시 녹색 공간의 계획 시행에 영향을 미치는 요소들을 탐구하고자 한다. 본 연구는 다변량 선형 회귀 모형을 이용하여 베이징의 두 그린벨트를 대상으로 삼아 도시체계요소 및 계획정책요소(독립 변수)와 그린벨트 내의 건설용 토지의 증가(종속 변수)간의 상관관계를 검증하였다. 인구밀집과 건설용 토지가 확장될 수 있는 동력의 영향을 받아 산지, 물가, 단위 면적당 임대료, 대중교통의 접근성, 신설된 국가 소유의 건설용 토지 등 도시체계요소는 녹색 밸트 내의 건설용 토지의 규모 변화와 상관관계를 보인다는 것을 알 수 있었다.

• Mycobiology
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• 제47권2호
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• pp.180-190
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• 2019

In this study, eight-month-old ectomycorrhizae of Tuber borchii with Corylus avellana were synthesized to explore the influence of T. borchii colonization on the soil properties and the microbial communities associated with C. avellana during the early symbiotic stage. The results showed that the bacterial richness and diversity in the ectomycorrhizae were significantly higher than those in the control roots, whereas the fungal diversity was not changed in response to T. borchii colonization. Tuber was the dominant taxon (82.97%) in ectomycorrhizae. Some pathogenic fungi, including Ilyonectria and Podospora, and other competitive mycorrhizal fungi, such as Hymenochaete, had significantly lower abundance in the T. borchii inoculation treatment. It was found that the ectomycorrhizae of C. avellana contained some more abundant bacterial genera (e.g., Rhizobium, Pedomicrobium, Ilumatobacter, Streptomyces, and Geobacillus) and fungal genera (e.g., Trechispora and Humicola) than the control roots. The properties of rhizosphere soils were also changed by T. borchii colonization, like available nitrogen, available phosphorus and exchangeable magnesium, which indicated a feedback effect of mycorrhizal synthesis on soil properties. Overall, this work highlighted the interactions between the symbionts and the microbes present in the host, which shed light on our understanding of the ecological functions of T. borchii and facilitate its commercial cultivation.

• Journal of Periodontal and Implant Science
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• 제49권4호
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• pp.237-247
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• 2019

Purpose: To analyze the maxillary sinus anatomy over edentulous ridges in the bilateral posterior maxillary area in Taiwanese patients using cone-beam computed tomography (CBCT). Methods: In total, 101 anatomical sites from 61 patients, including 32 premolar and 69 molar regions, were analyzed using CBCT. Measurements were made of the width and height of edentulous ridges, the thickness of the lateral wall of the maxillary sinus, and the presence of a sinus septum and the posterior superior alveolar artery (PSAA). A statistical analysis of the measurements was performed, and correlations among the measurements were assessed. Results: The average ridge width was $10.26{\pm}3.16mm$, with a significantly greater ridge width in the second molar region than in the premolar region. The mean residual ridge height was $8.55{\pm}4.09mm$, and ridge height showed an opposite trend from ridge width for the premolar and molar regions. A sinus septum was present at 5.9% of the sites, and the PSAA was observed in 24.5%. The average thickness of the lateral wall of the maxillary sinus was $2.08{\pm}0.94mm$, with no significant difference between the tooth position and lateral wall thickness. Conclusions: This study presents the anatomical features of the maxillary sinus, which should be considered in sinus lift procedures for implant placement, in the Taiwanese population. The use of CBCT is recommended to avoid intraoperative complications.

• 한국정보통신학회논문지
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• 제23권9호
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• pp.1139-1145
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• 2019

한정된 위성통신망 자원을 효율적으로 사용하기 위해서는 통신망에 대한 성능과 사용량을 파악하는 것이 우선이다. 본 논문에서는 K-water 홍수예보 경보망으로 운영 중인 위성통신시스템에서 시스템의 운영 효율성과 안정성을 분석하기 위하여, 중심국과 관측국간에 다운로드 및 업로드의 속도를 측정하는 FTP 및 핑 시험과 네트워크 트래픽 분석 방법을 도입하였다. 도입한 시험방법에 의한 전송속도를 측정한 결과, TCP 가속기의 영향은 관측국에서 다운로드시 120% 속도 향상이 되었으며, 데이터의 크기에 따른 차이가 발생하였고, 트래픽 분석에서는 네트워크상에 접속되는 프로토콜 종류와 사용량을 파악하였다. 도입한 위성수문관측시스템의 성능 시험 및 트래픽 분석을 통하여 위성통신시스템의 환경보완 및 개선점을 도출하여 통신망의 운영 효율성과 안정성 향상을 기대할 수 있도록 하였다.

• 한국음향학회지
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• 제38권3호
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• pp.290-301
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• 2019

본 논문에서 제안하는 알고리즘은 수중에서 협대역 지속파 능동 소나를 이용하여 표적 반향음을 탐지하는 문제를 다루고 있다. 능동 소나에서 표적 탐지를 위해 방사한 핑 신호는 주변의 많은 산란체에 의해 반사되는 신호를 만들어내며, 이를 잔향이라 한다. 본 논문에서 제안하는 알고리즘은 잔향 환경에서 낮은 도플러의 표적 반향음을 탐지하는 것을 목표로 한다. 제안하는 알고리즘은 빔공간 다채널 비음수 행렬 분해 기법을 기반으로 하여 방위, 주파수, 시간 기저를 추정하며, 특히 기저를 두 개의 기저집단 -잔향음 기저집단과 반향음 기저집단으로 나누어 독립적으로 추정한다. 제안하는 알고리즘의 성능을 평가하기 위하여 합성된 잔향 신호를 이용하여 시뮬레이션을 진행하였으며, 시뮬레이션 결과 제안하는 알고리즘이 기존의 알고리즘에 비해 향상된 성능을 보이는 것을 확인할 수 있었다.

• Yonsei Medical Journal
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• 제59권9호
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• pp.1064-1071
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• 2018

Purpose: To explore the influence of S100 calcium binding protein A4 (S100A4) knockout (KO) on methionine-choline-deficient (MCD) diet-induced non-alcoholic fatty liver disease (NAFLD) in mice. Materials and Methods: S100A4 KO mice (n=20) and their wild-type (WT) counterparts (n=20) were randomly divided into KO/MCD, Ko/methionine-choline-sufficient (MCS), WT/MCD, and WT/MCS groups. After 8 weeks of feeding, blood lipid and liver function-related indexes were measured. HE, Oil Red O, and Masson stainings were used to observe the changes of liver histopathology. Additionally, expressions of S100A4 and proinflammatory and profibrogenic cytokines were detected by qRT-PCR and Western blot, while hepatocyte apoptosis was revealed by TUNEL staining. Results: Serum levels of aminotransferase, aspartate aminotransferase, triglyceride, and total cholesterol in mice were increased after 8-week MCD feeding, and hepatocytes performed varying balloon-like changes with increased inflammatory cell infiltration and collagen fibers; however, these effects were improved in mice of KO/MCD group. Meanwhile, total NAFLD activity scores and fibrosis were lower compared to WT+MCD group. Compared to WT/MCS group, S100A4 expression in liver tissue of WT/MCD group was enhanced. The expression of proinflammatory ($TGF-{\alpha}$, $IL-1{\beta}$, IL-6) and profibrogenic cytokines ($TGF-{\beta}1$, COL1A1, ${\alpha}-SMA$) in MCD-induced NAFLD mice were increased, as well as apoptotic index (AI). For MCD group, the expressions of proinflammatory and profibrogenic cytokines and AI in KO mice were lower than those of WT mice. Conclusion: S100A4 was detected to be upregulated in NAFLD, while S100A4 KO alleviated liver fibrosis and inflammation, in addition to inhibiting hepatocyte apoptosis.

• Tissue Engineering and Regenerative Medicine
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• 제15권6호
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• pp.751-760
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• 2018

BACKGROUND: Bone tissue engineering based on pluripotent stem cells (PSCs) is a new approach to deal with bone defects. Protocols have been developed to generate osteoblasts from PSCs. However, the low efficiency of this process is still an important issue that needs to be resolved. Many studies have aimed to improve efficiency, but developing accurate methods to determine efficacy is also critical. Studies using pluripotency to estimate efficacy are rare. Telomerase is highly associated with pluripotency. METHODS: We have described a quantitative method to measure telomerase activity, telomeric repeat elongation assay based on quartz crystal microbalance (QCM). To investigate whether this method could be used to determine the efficiency of in vitro osteogenic differentiation based on pluripotency, we measured the pluripotency pattern of cultures through stemness gene expression, proliferation ability and telomerase activity, measured by QCM. RESULTS: We showed that the pluripotency pattern determined by QCM was similar to the patterns of proliferation ability and gene expression, which showed a slight upregulation at the late stages, within the context of the general downregulation tendency during differentiation. Additionally, a comprehensive gene expression pattern covering nearly every stage of differentiation was identified. CONCLUSION: Therefore, this assay may be powerful tools for determining the efficiency of differentiation systems based on pluripotency. In this study, we not only introduce a new method for determining efficiency based on pluripotency, but also provide more information about the characteristics of osteogenic differentiation which help facilitate future development of more efficient protocols.

• Journal of Periodontal and Implant Science
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• 제51권5호
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• pp.298-315
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• 2021

Purpose: Peri-implantitis therapy and implant maintenance are fundamental practices to enhance the longevity of zirconia implants. However, the use of physical decontamination methods, including hand instruments, polishing devices, ultrasonic scalers, and laser systems, might damage the implant surfaces. The aim of this systematic review was to evaluate the effects of physical decontamination methods on zirconia implant surfaces. Methods: A systematic search was conducted using 5 electronic databases: Ovid MEDLINE, PubMed, Scopus, Web of Science, and Cochrane. Hand searching of the OpenGrey database, reference lists, and 6 selected dental journals was also performed to identify relevant studies satisfying the eligibility criteria. Results: Overall, 1049 unique studies were identified, of which 11 studies were deemed suitable for final review. Air-abrasive devices with glycine powder, prophylaxis cups, and ultrasonic scalers with non-metal tips were found to cause minimal to no damage to implantgrade zirconia surfaces. However, hand instruments and ultrasonic scalers with metal tips have the potential to cause major damage to zirconia surfaces. In terms of laser systems, diode lasers appear to be the most promising, as no surface alterations were reported following their use. Conclusion: Air-abrasive devices and prophylaxis cups are safe for zirconia implant decontamination due to preservation of the implant surface integrity. In contrast, hand instruments and ultrasonic scalers with metal tips should be used with caution. Recommendations for the use of laser systems could not be fully established due to significant heterogeneity among included studies, but diode lasers may be the best-suited system. Further research-specifically, randomised controlled trials-would further confirm the effects of physical decontamination methods in a clinical setting.