• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.6
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• pp.242-246
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• 2022

The purpose of this study is to report on the clinical improvement of a patient treated with Korean medicine for Post COVID-19 syndrome. A 52-year-old male patient with headache and chronic fatigue was diagnosed with post-acute COVID-19 syndrome. He had clinical symptoms such as headache, sweating, fatigue, and insomnia and was treated with acupuncture and herbal medicines such as Sasammaekmoondong-tang. To assess the treatment outcomes, the authors used the Fatigue Severity Scale (FSS) and the Numeral Rating Scale (NRS). Following treatment, fatigue improved, with the FSS score dropping from 48 at the first visit to 18 at the final visit, and clinical symptoms such as headache and insomnia disappeared. According to the findings of this study, Korean Medicine could be used in the clinic to treat post-COVID-19 complications.

• Journal of Korean Clinical Nursing Research
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• v.18 no.3
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• pp.368-380
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• 2012

Purpose: The purpose of this study was to evaluate the effects of a home-based video exercise program on cancer-related fatigue, physiological and psychological status in patients with colon and rectal cancers undergoing chemotherapy. Methods: The study design was a non-equivalent control group non-synchronized design. Data were collected from patients with colo-rectal cancers in Yonsei cancer center from July 5th to October 31st in 2011. There were 40 participants; 20 in the experimental group and 20 in the control group. The structured questionnaire was used to measure fatigue, physical function and emotional status. Data were analyzed using SPSS 18.0 and a chi-squre test, Fisher's exact test, Mann-Whitney U test and Wilcoxon signed- rank test were conducted to examine the homogeneity and the research hypotheses. Results: There was a statistically significant difference in White Blood Cell count in the experimental group compared with that of the control group. The exercise group showed a slight decrease of White Blood Cell count compared with that of the control group after 4 week program (z=-2.935, p=.003). However, there were no significant differences in fatigue, physiological and psychological status between the two groups. Conclusion: In this study, the developed video exercise program was effective in markedly slightly decreasing White Blood Cell count in patients with colo-rectal cancers undergoing chemotherapy. Therefore, utilizing the video exercise program can be an useful method to promote health among patients with cancer in clinical practice.

• Korean Journal of Veterinary Research
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• v.35 no.2
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• pp.245-254
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• 1995

The density of ATP-sensitive potassium($K_{APT}$) channels, that open as intracellular ATP concentration falls below a critical level, is very high in skeletal muscle surface membrane and those high density may imply that $K_{ATP}$ channels have very important physiological roles. To elucidate a role of $K_{ATP}$ in relation to fatigue, the modulating effects of potassium channel openers and blockers on the fatigue velocity(FV) of mouse extensor hallucis longus muscle(EHL) were investigated in vitro. Twitch contraction was induced by an electrical field stimulation (EFS: 24-48V, 20ms, 0.2-4Hz) and resulting contraction force was isometrically recorded. The twitch forces were gradually decreased to 25% of initial contraction force(ICF) in $37.52{\pm}1.55sec$($mean{\pm}s.e.m.$, n=135), indicating the fatigue phenomena. The mean velocity for development of the fatigue was measured during the period that twitch force decreased to half($FV_{0/0.5}$) and during the period from half to 25%($FV_{0.5/0.25}$) of ICF. The fatigue was induced once every one hour and the tissue response was stable for up to 4 hours. In control condition, ICF was $5.8{\pm}0.12g$ (n=144) and decreased to 50% of ICF with the mean fatigue velocity of $0.182{\pm}0.006g/sec$($FV_{0/0.5}$, n=135) and from 50% to 25% of ICF with $0.084{\pm}0.004g/sec$($FV_{0.5/0.25}$, n=135). Cromakalim($50{\mu}M$) significantly increased $FV_{0.5/0.25}$(n=4). Glibenclamide($IC_{50}>50{\mu}M$), $Ba^{2+}$($IC_{50}=10{\mu}M$), 4-aminopyridine($FV_{0/0.5}$, $IC_{50}=0.5mM$; $FV_{0.5/0.25}$, $IC_{50}=2mM$) decreased both $FV_{0/0.5}$ and $FV_{0.5/0.25}$ concentration-dependently up to 75%. $TEA^+$(30mM), E-4031($10{\mu}M$), tolbutamide(1mM) decreased $FV_{0.5/0.25}$, but apamin(300nM) and $TEA^+$(10mM) showed no significant effects. Our results suggest that activation of the $K_{ATP}$ channels may be major cause of $K^+$ outflux during development of the fatigue and the isolated EHL muscle could be an useful experimental preparation in studying the fatigue phenomena in skeletal muscle. In addition, the possibility of activation of delayed rectifier during the fatigue development remains to be studied further.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.61 no.1
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• pp.55-58
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• 2012

By using EEG and HRV, subjects were estimated on their psychological and physiological reaction when reading psychrometric chart in 7 point century font, in an environmental test room in the condition of temperature 25[$^{\circ}C$], relative humidity 50[RH%], air current speed 0.02[m/sec], giving variation in illuminance to 0.1, 300, 600, 1000, 1300 and 1600[lux]. As a result, it was at 1300[lux] that absolute ${\alpha}$ wave, SMR, SDNN were most vitalized, and also both sides ${\alpha}$ wave asymmetry index, SEF50, HRT, stress and fatigue degree were at the lowest. It was found that a certain illuminance which minimizes psychological stress and fatigue degree while enhancing concentration and task achievement stably does exist.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.67 no.2
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• pp.100-105
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• 2018

In this paper, we determined the driver's stress and fatigue level through physiological signals of a driver in the connected car environment, accordingly designing and implementing the architecture of the connected cars' platforms needed to provide services to make the driving environments comfortable and reduce the driver's fatigue level. It includes a gateway between AVN and ECU for the vehicle control, a framework for native applications and web applications based on AVN, and a sensing device and an emotion estimation engine for application services. This paper will provide the element technologies for the connected car-based convergence services and their implementation methods, and reference models for the service design.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2002.05a
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• pp.65-70
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• 2002

본 연구에서는 3시간 연속 운전에 따른 운전자의 피로감 및 생리적 반응을 고속도로 주행과 시내주행으로 실시하여 비교 검토하였다. 중추신경계 반응의 측정결과 양 주행조건 모두 각성되고 불쾌하였으나 시내주행의 경우가 상대적으로 각성되고 쾌한 경우가 많았던 것으로 나타났다. 한편, 시내주행의 경우는 심박수의 변화가 심하였으나, 고속도로의 주행에서는 눈깜빡임율이 크게 증가하였다. 따라서 2가지 주행 조건 모두 운전시간이 경과함에 따라 피로감을 느끼나 그러한 피로감을 느끼는 원인이나 현상은 상이한 것으로 나타났다.

• Proceedings of the ESK Conference
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• 1997.10a
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• pp.414-425
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• 1997

Standark polysomnograms, and questionnaires were measured using 4 subjects during simulated 150m heliox saturation dives. These measurements were performed on 4 pre-dive nights, 8 bottom nights, 6 decompression nights and post decompression nights. Sleep disturbances caused by frequent awakening were found throughout the dive period, but the disturbances were more intense on the second and fourth nights at the bottom and on the third and fourth nights of decompression. Stage 4 of sleep decreased every night at the bottom and from the first through third nights of decompression. The subjective self-evaluation of sleep was in agreement with the physiological variables. Complaints of subjective feeling of fatigue slightly increased throughout the dive period. It could be surmised that sleep disturbance or fatigue was not as significant under the 150m deep hyperbalic environment of He-O/ sub 2/ mixture, and therefore should be able to be coped with partially, through there moght be individual differences in adaptation.

• Journal of the Korean Society of Clothing and Textiles
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• v.18 no.5
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• pp.615-621
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• 1994

This study was carried out to investigate the effect of clothing habit on physiological adaptation to the change of season. The survey of clothing weight in fall '||'&'||' winter for 2 years, the frequency of cold infection in winter and degree of fatigue was performed with 110 female high school students. The actual condition of clothing and the correlations between clothing weight and cold infection, and between the clothing weight and degree of fatigue were suveyed. The results are followed as; 1. The clothing insulation was nearly same to indoor standard clothing insulation in H hun wearing normal clothing, but was higher 2 clo in S hun clothed uniform. Especially in spite of similar enviromental condition the clothing weight, minimum '||'&'||' maximum and variation of clothing weight for 2 years were showed to be heavier in S hun than H hun. Also indoor thermal sensation felt by the subjects indicated "cold", and the difference between clothing insulation and standard clothing insulation showed increase gradually. 2. L group was indicated to be lower in cold infaction ratio than M '||'&'||' H group, and the correlation between clothing group and cold infection ratio was recognized to be significant (p<0.05). And H hun and L-H group showed to be lower in cold infection ratio than S hun, H-L group. 3. The coefficience between clothing weight and degree of fatigue was recognized to be significant (p<0.05).

• Journal of Nutrition and Health
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• v.38 no.2
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• pp.117-124
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• 2005

We investigated the effects of prolonged exposure in hot environmental condition and ingestion of fluid on various physiological variables including plasma glucose, lactate, the rating of perceived exertion (RPE), and heart rate as well as golf putting performance. Six male professional golfers were voluntarily participated in three different putting trials which were separated by seven days of time interval period. Three different putting trials were conducted at either 20℃ or 32℃, or 32℃ + Fluid ingestion. Performing 32℃ + Fluid ingestion trial, all subject ingested sport drink as much as their body mass was decreased. For each experiment, all subjects were undertaken total 48 putting, which separated by four x 12 putting in four different time points (i.e., Rest, 1 hr, 2 hr, and 3 hr). Plasma glucose concentration was significantly decreased with hot ambient condition but it was almost fully recovered by fluid ingestion. Plasma lactate concentration was significantly higher when subjects were exposed in hot environmental condition, and it did not change with fluid ingestion. There was a no different in putting performance and psychological fatigue level (performed by GRID test) at any environmental conditions. The RPE, commonly used for evaluating of physical fatigue level, was significantly dropped by fluid ingestion which indicates lower physical fatigue level. In addition to this, heart rate (HR) was also significantly decreased after fluid ingestion. Based on these results, it was concluded that the ingestion of fluid during prolonged exposure in hot ambient condition decrease the degree of physical fatigue levels and heart rate, which will possibly improve the golf performance when exposed in extreme weather condition in summer. (Korean J Nutrition 38(2): 117～124, 2005)

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.3
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• pp.1145-1150
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• 2011

The purpose of this study was to determine the relationships between fatigue, stress resistance and emotion in middle aged women under the developmental crisis using a brain wave measurement which is a cranial physiological index. From March 2005 to June 2009, women aged between 35 and 65 (N=4402) who volunteered for a brain wave test at the KRIJUS( Korea Research Institute of Jungshin Science) were monitored the brain function quotient (tension degree, anti-stress quotient and emotional quotient). Correlation and time-series linear analysis revealed significantly the relationships between fatigue, stress resistance and emotion. Also, according to the emotional propensity, cheerful propensity was higher in the cheerful and depressed propensity, positive propensity was higher in the positive and negative propensity, during the whole test, cheerful and positive propensity was higher. Therefore, it is necessary to increase the quality of life by decreasing fatigue and stress level of the middle-aged women to maintain and increase their individual health and the better family relationship.