• 동의생리병리학회지
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• 제26권6호
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• pp.953-959
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• 2012

The purpose of this study is to report the hemostatic effects of Kungkwikyoae-tang for abnormal uterine bleeding. Kungkwikyoae-tang has been known as a useful herbal medication for uterine bleeding. We treated patients who had been suffering from abnormal uterine bleeding with herb-medication, acupuncture therapy, pharmacopuncture therapy and moxa therapy. We prescribed Kungkwikyoae-tang three times a day. The improvement of symptoms were measured by checking patient bleeding volume, frequency and other physical signs. After Kungkwikyoae-tang was given, abnormal uterine bleeding volume and frequency was reduced and other physical symptoms were improved. This case study shows that Kungkwikyoae-tang has a hemostatic effects against the abnormal uterine bleeding.

• 원예과학기술지
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• 제31권4호
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• pp.483-489
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• 2013

The abnormal seedlings, a common physiological anomalies, emerged during embryo rescue severely restricted grape breeding. To enhance the efficiency of the seedless grape breeding by reducing the production of abnormal seedlings in the course of embryo rescue, we investigated the effects of genotype, media type, embryo style, pre-chilling on the deformity rate of the abnormal seedlings during embryo rescue. The abnormal seedlings were firstly classified into seven categories based on their morphology. Our results indicated that the emergence of abnormal seedlings was highly dependent on the female parent genotype. Polyembryony was advantageous to diminish the number of abnormal plantlets and the germination rate of embryo was 100%. We also found that pre-chilling treatment could reduce the number of abnormal plantlets and promote the embryo germination. The abnormal plantlets were reduced significantly by the addition of $ZnSO_4$ $10{\mu}mol{\cdot}L^{-1}$ or mashed-banana $500mg{\cdot}L^{-1}$ to either embryo development or germination media. Transferring the abnormal seedlings onto the suitable fresh media in 4 weeks after embryo germination provided an effective way to transform them into normal seedlings.

• 동의생리병리학회지
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• 제31권1호
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• pp.1-7
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• 2017

There are two kinds of body fluid metabolism in Traditional Korean Medicine based on 'Internal Classic'("內經"); one is metabolism of body fluid(津液) meaning metabolism of physiological substance, and another is metabolism of humor meaning a metabolic process that excretes waste out of the body. 'Phlegm-retained fluid'(痰飮) is a typical pathological condition caused by abnormal fluid metabolism in Traditional Korean Medicine. As a result of reviewing the literature on 'phlegm-retained fluid'(痰飮), the following facts were found; 'Phlegm-retained fluid'(痰飮) is formed by abnormal state of metabolism of body fluid(津液). In other words, because of the action of various etiologies, qi(氣) and body fluid(津液) metabolism can have abnormal conditions and these metabolic disorders cause formation of 'phlegm-retained fluid'(痰飮). Treatments for 'phlegm-retained fluid'(痰飮) include the following: Eliminating the causes of illness, recovery of metabolism of qi(氣) and body fluid(津液), and functional recovery of pancreas and kidney related to body fluid(津液) metabolism. These treatments are distinguished from promotion of sweating(發汗) and helping urination, the treatments for humor metabolism abnormality.

• 대한전기학회논문지:시스템및제어부문D
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• 제52권2호
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• pp.112-119
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• 2003

This paper proposes a model of SP(silent period) generation in masseter muscle by means of computer simulation. The model is based on the anatomical and physiological properties of trigeminal nervous system. In determining the SP generation pathway, evoked SPs of masseter muscle after mechanical stimulation to the chin are divided into normal and abnormal group. Normal SP is produced by the activation of mechanoreceptors in periodontal ligament. The activation of nociceptors contributes to the latter part of normal SP, abnormal extended SP is produced. As a result, the EMG signal generated by a proposed SP generation model is similar to both real EMG signal including normal SP and abnormal extended SP with TMJ patients. The result of this study have shown differences of SP generation mechanism between subjects both with and without TMJ dysfunction.

• 성인간호학회지
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• 제16권3호
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• pp.460-469
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• 2004

Purpose: The purpose was to investigate the physiological parameter and physical health status and health perception in the elderly, and to find the correlation between these variables. The subjects were 139 in Kyungi senior center. Method: The instruments for this study were physiological parameters, which were composed of vital capacity, blood pressure, pulse oxygenation, hand grip power, body fat and physical health status scale developed by researcher, and health perception scale developed by Ware(1976). The data were analyzed by the SPSS-PC 11.0 version. Results: 1) 7.9% of subjects were included in abnormal range of vital capacity, 40.3% were systolic hypertension and 11.5% were diastolic hypertension. And 92.1% were included in normal range of pulse oxygenation, 79.8% were weakened hand grip power, and 10.1% of subjects were included in normal range of body fat. 2) The total mean score of the physical health status was 26.34 of a possible maximum score of 45. The physical health status score of women was lower than man's. 3) The mean score of man's health perception was 24.52 and women's was 20.39 of a possible maximum score of 44. 4) There was a significant positive correlation between hand grip power and physical health status(r=.28, p=.001). And a significant correlation between physical health status and health perception was found (r=.24, p=.004). Conclusion: It is concluded that the blood pressure, hand grip power and body fat among the physiological parameters of elderly subjects in Kyungi senior center were included in abnormal range. The factors were related life style. therefore, it is suggested that the health education to change life style for the elderly is needed.

• Journal of Korean Biological Nursing Science
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• 제17권3호
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• pp.219-227
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• 2015

Purpose: This study was conducted to review physiological mechanisms of internet addiction and to construct a theoretical framework for cognitive behavioral therapy for internet addicts. Methods: We searched for relevant literature in the PubMed and RISS databases using the terms "internet addiction", "internet game addiction", "internet abuser", and "online game". Only English, full-text articles published from 2000 to 2015 were included in this review of physiological indicators of internet addiction. Finally, 12 articles were selected for review. Results: The theoretical framework developed based on the review proposes that excessive internet use itself may induce physiological stress responses with an increase of stress-related hormones and neurotransmitters. Prolonged abnormal responses of these physiological features produce negative structural and functional changes in the prefrontal cortex, which is mainly involved in cognitive and executive functions. These changes may result in decreased cognitive function. As a stressor, excessive internet use leads to transforming voluntary use into involuntary, habitual use and thus promotes the development of internet addiction. Conclusion: The proposed theoretical framework encompasses cognitive processes that may contribute to the effects of internet use-induced physiological stress on internet addiction. We believe that this framework has important implications for developing cognitive behavioral strategies for internet addicts.

• 사상체질의학회지
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• 제21권3호
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• pp.107-121
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• 2009

1. Objectives: We aimed to know what are different in physiological and pathological symptoms associated with health state according to Sasang Constitution in women 2. Methods: We recruited 338 women between 10 and 80, excluding individuals who have physically or psychologically serious disease, or women in pregnancy among Korean population in Traditional Korea Clinics. We used CRF(Case Report Form, C-2009-002439) as measurement of physiological and pathological symptoms and SF-36 (Short Form-36) as measurement of health state We analyzed association between physiological and pathological symptoms and health state with Two-way ANOVA 3. Results: There are 9 different symptoms associated with health state, such as digestion state, uncomfortable problem in belly, indigestion in bad condition, abnormal sweat, night sweat, clean in urine, no problem in urine, feel heavy in chest according to Sasang constitution. 4. Conclusions: Physiological and pathological symptoms are associated with health state and some symptoms associated with health state are different according to Sasang Constitution in women.

• 대한의생명과학회지
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• 제17권2호
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• pp.105-112
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• 2011

We evaluated whether liver markers such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyltranspeptidase (GGT), and bilirubin have a relationship with other physiological factors in the normal (n=115) and fatty liver subjects (n=122) and there are differences between the two populations. Body indices were higher in the fatty liver group than in the normal group. Liver markers and blood pressure (BP) were greater in the fatty liver group than in the normal group. AST and ALT levels were positively correlated with body indices in the fatty liver group, but not in the normal group. AST, ALT and GGT levels in the fatty liver group had positive relationship with cardiovascular indices (CI). ALP and bilirubin levels were negatively associated with some of CI. Liver markers were negatively or positively correlated with inflammatory markers, thyroid hormones, or several biochemical markers levels. These findings suggest that abnormal changes in liver markers may be useful tool for diagnosis or prognosis of development of cardiovascular and/or inflammatory diseases as well as metabolic syndrome.

• Animal cells and systems
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• 제12권3호
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• pp.127-136
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• 2008

Caspase-11 has been known as a dual regulator of cytokine maturation and apoptosis. Although the role of caspase-11 under pathological conditions has been well documented, its physiological role has not been studied much. In the present study, we investigated a possible physiological function of caspase-11 during immune response. In the absence of caspase-11, immunized spleen displayed increased cellularity and abnormal germinal center structure with disrupted microarchitecture. The rate of cell proliferation and apoptosis in the immunized spleen was not changed in the caspase-11-deficient mice. Furthermore, the caspase-11-deficient peritoneal macrophages showed normal phagocytotic activity. However, caspase-11-/-splenocytes and macrophages showed defective migrating capacity. The dysregulation of cell migration did not seem to be mediated by caspase-3, interleukin-$1{\alpha}$ or interleukin-$1{\beta}$ which acts downstream of caspase-11. These results suggest that a direct regulation of immune cell migration by caspase-11 is critical for the formation of germinal center microarchitecture during immune response. However, humoral immunity in the caspase-11-deficient mice was normal, suggesting the formation of germinal center structure is not essential for the affinity maturation of the antibodies.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3737-3740
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• 2014

Background: Abnormal uterine bleeding (AUB) is the most important symptom of endometrial hyperplasia and endometrial curettage (EC) is the gold standard diagnostic procedure. We present the results of patients who underwent EC for AUB and the efficacy of progestin administration in those with endometrial hyperplasia. Materials and Methods: A total of 415 female patients who presented to Duzce Public Hospital in 2011-2012 for AUB and who underwent EC were included. We determined the reasons for AUB, and females with hyperplasia were treated with 10 mg/day medroxyprogesterone acetate for 14 days/month or 160 mg/day megestrol acetate continuously for 3 months. We evaluated the efficacy of progestins for periods of three and/or six cycles by repeating EC. A statistical analysis of specific endometrial causes according to age of presentation was conducted using the chi-square test. Results: Among the 415 females (average age, 53.5 years) followed for 6 months, 186 had physiological changes (44.8%), 89 had simple hyperplasia (21.44%), 1 had atypical hyperplasia (0.2%), 6 had (1.44%) complex hyperplasia, 3 had (0.72%) atypical complex hyperplasia, and 5 had adenocarcinoma (1.2%). Regression rates were 72.7-100%, and the optimum results were observed after 6 months of hormonal therapy. Conclusions: The main cause of AUB was physiological change. Progestin therapy resulted in significant regression even in females with atypical hyperplasia.