• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2009년도 추계학술대회
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• pp.186-189
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• 2009

본 연구에서는 폭력영상 시청 시 개인의 공격성향에 따른 생체신호(ECG, GSR)의 변화를 분석하였다. 남자 23 명(21.4 세, ${\pm}1.8$ 세)의 피험자의 공격성을 설문지로 측정하였다. 실험은 Rest(15 분), 안정영상 시청(2 분 14 초), 폭력영상 시청(50 초), 안정영상 시청(2 분 14 초)으로 구성되어 있다. 폭력영상은 패싸움·마루타 실험장면을 보여주었으며, 안정영상은 바다·산·계곡 등의 영상을 보여주었다. 폭력영상 시청 시 개인의 공격성향과 ECG 신호 사이의 상관관계는 관찰 할 수 없었으나, GSR 신호와는 음의 상관관계를 관찰 할 수 있었다. 이 결과는 공격성이 높은 사람일수록 폭력영상 시청 시 생체신호 변화가 작을 수 있음을 시사한다.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2009년도 추계학술대회
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• pp.232-235
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• 2009

본 연구에서는 실시간으로 변화하는 사용자의 감성을 평가하여 각성 또는 이완으로 분류된 시선 정보 이미지를 저장하는 시스템을 구현하고자 한다. 사용자의 감성을 분류하기 위한 요소는 Larson과 Diner 가 정의한 2 차원 감성모델에서 각성, 이완 요소를 사용한다. 감성 상태를 분류하기 위하여 자율 신경계 중 착용과 휴대가 간편한 PPG 센서를 사용하며, PPG 를 분석하기 위한 변수로는 진폭의 양과 초당 Peak 의 빈도수를 사용한다. 머리에 고정할 수 있는 캠을 사용하여 사용자가 바라보는 시선 정보를 획득하고, 클라이언트 컴퓨터는 획득된 시선 정보를 UDP 통신을 사용해 서버 컴퓨터로 전송하는 시스템이다. 320(pixel)*240(pixel)*32(bit)인 영상 데이터를 1/30 로 압축하여 전송하며, 각성과 이완으로 분류되는 시점의 영상을 블록화하여 JPEG 이미지로 저장한다. 본 시스템은 실시간으로 변화되는 사용자의 감성 상태를 파악하여 이미지를 전송하고 서버 컴퓨터에 저장함으로써 당시 사용자가 느꼈던 감성들에 대해 피드백을 주고자 하는데 의의가 있다.

• 동의생리병리학회지
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• 제18권3호
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• pp.924-929
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• 2004

Pigmented villonodular synovitis is a rare proliferating process of the synovium, tendon sheaths and bursae usually affecting the bone and joints. The disease can be localized or diffuse. Patients with this condition typically present with symptoms of mild discomfort and associated swelling of the involved joint. However, the spectrum of presentations is broad. Diagnosis of Pigmented villonodular synovitis can be clinically difficult, and plain radiographs are usually nonspecific. Magnetic resonance imaging is a highly diagnostic modality in characterizing pigmented villonodular synovitis when it contains hemosiderin deposits exhibiting low signal intensity on all pulse sequences. Magnetic resonance imaging is recommended for accurate preoperative staging of the disease and for follow up after treatment. I report a case of pigmented nodular synovitis in the knee joint, with review of literatures.

• 대한의용생체공학회:의공학회지
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• 제16권3호
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• pp.345-352
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• 1995

The LPC cepstrum coefficients, which are an acoustic features of speech signal, have been widely used as the feature parameter for various speech recognition systems and showed good performance. The vocal tract area function is a kind of articulatory feature, which is related with the physiological mechanism of speech production. This paper proposes the vocal tract area function as an alternative feature parameter for speech recognition. The linear predictive analysis using Burg algorithm and the vector quantization are performed. Then, recognition experiments for 5 Korean vowels and 10 digits are executed using the conventional LPC cepstrum coefficients and the vocal tract area function. The recognitions using the area function showed the slightly better results than those using the conventional LPC cepstrum coefficients.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권4호
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• pp.304-308
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• 2005

The response of IPTG induction was investigated through the monitoring of the alkali consumption rate and buffer capacity during the cultivation of recombinant E. coli BL21 (DE3) harboring the plasmid pRSET-LacZ under the control of lac promoter. The rate of alkali consumption increased along with cell growth, but declined suddenly after approximately 0.2 h of IPTG induction. The buffer capacity also declined after 0.9 h of IPTG induction. The profile of buffer capacity seems to correlate with the level of acetate production. The IPTG response was monitored only when introduced into the mid-exponential phase of bacterial cell growth. The minimum concentration of IPTG for induction, which was found out to be 0.1 mM, can also be monitored on-line and in-situ. Therefore, the on-line monitoring of alkali consumption rate and buffer capacity can be an indicator of the metabolic shift initiated by IPTG supplement, as well as for the physiological state of cell growth.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1997년도 추계학술대회
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• pp.41-46
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• 1997

Lower esophageal sphincter (LES) is characterized by the ability to maintain a sustained pressure, and to relax allowing the passage of a bolus, whereas the esophagus is normally relaxed and contracts only briefly when required to produce peristalsis (fig. 1). The neuromuscular mechanisms that participate in the physiological regulation of these functions are not well understood, but it is thought that LES tone is spontaneous and regulated mostly through myogenic mechanisms, whereas LES relaxation and esophageal contraction are induced by neural mechanisms. Gastroesophageal reflux represents the effortless movement of gastric contents from stomach to esophagus. Because this phenomenon occurs in virtually everyone multiple times every day and in the majority of people without clinical consequences, the reflux per se is not disease. However in some cases, it can be pathologic, producing symptoms and signs called gastroesophageal reflux disease (GERD), which mechanism is not well known. It may result in heart burn, chronic esophagitis, aspiration pneumonia, esophageal strictures, and Barrett's esophagus.

• 동의생리병리학회지
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• 제24권5호
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• pp.753-757
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• 2010

The objectives of this paper is to propose the pharmacoepidemiologic methodology to Research for Sasang Constitutional Pharmacology. We mainly searched "Journal of Pharmacoepidemiology and Risk Management". And we also searched "J Korean Oriental Med.", "J of Sasang Constitutional Med.", "J. Oriental Physiology & Pathology", "Korean J Orient Int Med." using these kew words - "adverse event" or "side effect" and "Sasang Contitution" or "Constitution" or "Constitutional medicine". Through the examination of the Pharmacoepidemiologic methodology and current research for sasang constitiutional pharmacology, we could establish the proposal to collect objective constitutional medical reaction. For the actualization of this proposal, the more advanced studies will have to be carried out continuously.

• BMB Reports
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• 제34권2호
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• pp.95-101
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• 2001

Tissue transglutaminase (TGII, $G{\alpha}h$) belongs to a family of enzymes which catalyze post-translational modification of proteins by forming isopeptides via $Ca^{2+}$-dependent reaction. Although TGII-mediated formation of isopeptides has been implicated to play a role in a variety of cellular processes, the physiological function of TGII remains unclear. In addition to this Tease activity, TGII is a guanosine triphosphatase (GTPase) which binds and hydrolyzes GTP It is now well recognized that the GTPase action of TGII regulates a receptor-mediated transmembrane signaling, functioning as a signal transducer of the receptor. This TGII function signifies that TGII is a new class of GTP-binding regulatory protein (G-protein) that differs from "Classical" heterotrimeric G-proteins. Regulation of enzyme is an important biological process for maintaining cell integrity. This review summarizes the recent development in regulation of TGII that may help for the better understanding of this unique enzyme. Since activation and inactivation of GTPase of TGII are similar to the heterotrimeric G-proteins, the regulation of heterotrimeric G-protein in the transmembrane signaling is also discussed.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2003년도 춘계학술대회 논문집
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• pp.1-4
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• 2003

본 연구는 경편성물의 특성에 영향을 미치는 중요한 구조변수인 조직, 편환의 계폐여부, 가이드바의 상호 움직임 방향에 따른 소리특성과 생리적 반응 사이의 관계를 파악함으로써 총합적 감성소재 설계를 위한 기초 자료를 제공하고자 하였다. 직물소리발생장치를 이용하여 7가지의 경편성물에 대한 마찰음을 녹음한 후, 이를 마찰음이 유발하는 생리반응을 측정하여 slow alpha파, fast beta파, ECG R-R, RESP, HF/LF, SCL, PV등을 분석하였다. 조직에 따라서는 LPT, Loundness(Z), Roughness(Z)와 Fluctuation strength(Z) 가장 큰 Sharkskin에서 fast beta파, ECG R-R, RESP는 증가하였으며 slow alpha파, PV, HF/LF는 감소하였다. 편환의 개폐여부에서는 폐환보다는 개환에서 Loudness(Z), Sharpness(Z), Fluctuation strength(Z)가 증가하였으며 RESP는 증가하고 HF/LF는 감소하여 개환이 더 불쾌한 감성을 유발하였다. 가이드바의 상호 움직임 방향은 counter보다는 parallel에서 slow alpha의 변화량이 감소하고 fast beta의 변화량이 증가하여 counter보다는 parallel이 더 불쾌한 감성을 유발하는 것으로 보인다. 또한 편성물의 음향특성 중 ΔL, Δf 와 Roughness(Z), Fluctuation Strength(Z)가 생리반응을 예측하는 중요한 요인으로써 나타났다.

• 한국작물학회지
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• 제44권3호
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• pp.302-307
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• 1999

Hamlet (PI549276) possessing 2RL was obtained by cross between a wheat cultivar ND7532 (Froid/Centurk) and a rye cultivar Chaupon. Chaupon was known to have resistant gene to biotype L of Hessian fly [Mayetiola destructor (Say)] larvae. The wheat-rye translocation line (Coker797*4/Hamlet) was also known to be resistant to biotype L of Hessian fly larvae. We analysed a set of 96 ESTs from the wheat-rye translocation line (2BS/2RL). ESTs were classified by various physiological processings, such as primary metabolism, secondary metabolism, transcription, translation, transport, signal transduction, defense, transposable element, and others. Three sequences encoding thioredoxin peroxidase, 26S rRNA, and rubisco small subunits were homologous to registered genes in rye. Although limited number of clones were used to develop ESTs, these clones and their sequence information may be useful for researchers studying general physiology and molecular biology on the translocation line.