• Title/Summary/Keyword: Physiological Function

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Thermo-physiological Responses by Presence of Vents and Difference in Clothing Length for Construction Site Working Clothes (통기구 유무와 옷 길이 차이에 따른 건설현장 작업복의 온열생리반응)

  • Kim, Seong-Suk;Kim, Hee-Eun
    • Fashion & Textile Research Journal
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    • v.20 no.2
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    • pp.202-209
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    • 2018
  • This study examined thermo-physiological responses according to the design change of construction site working clothes (control (C) working clothes; prototype (P) working clothes). We measured rectal temperature, skin temperature, micro-climate within the clothes and sweat rate. In the evaluation of physiological functionality, based on pattern improvement in working clothes, P working clothes showed significantly lower rectal temperatures, trunk and thigh skin temperatures than C working clothes. It is preferable that rectal temperature should be kept low during work that is not favorable to an increase in body temperature. P working clothes were more physiologically functional than C working clothes. In addition, P working clothes showed significantly lower temperatures in the trunk and thigh parts in a micro climate temperature. We could explain that the side seam zipper on the pants and the gusset on armpit parts create an air permeability effect of lowering the temperature of micro-climate. Aggressive ventilation through the slit of the garment is an important factor for the restoration of the physiological function of the worker at rest between work. Sweat rate showed a higher level in C working clothes than P working clothes. When working in a hot environment, workwear needs to be designed so that the worker is not exposed to thermal stress. Therefore, it was evaluated that the P work clothes used in this study alleviated the physiological burdens of heat.

Effects of Hand Reflexology on Physiological.Emotional Responses and Immunity in the Patients with Chronic illness; Chronic renal failure patients and Cancer patients (손 반사요법이 만성질환자의 생리.정서적 반응과 면역 반응에 미치는 효과 : 만성신부전증과 암 환자 중심으로)

  • 이정희;오세영;박옥순;권인각;정미아;이은아
    • Journal of Korean Academy of Nursing
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    • v.32 no.5
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    • pp.716-726
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    • 2002
  • The purpose of this study was to explore the effects of hand reflexology on the physiological.emotional responses and immunity of the patients with chronic illness. This study looked specifically at patients with chronic renal failure(CRF) and cancer patients. Method: This study was designed as a quasi-experimental nonequivalent control group pre and post test. Subjects were 54 patients who received dialysis and chemotherapy in one hospital. Thirty-one patients were assigned to the experimental group and 23 to the control group. The hand reflexology was applied to both hands of the experiment group for ten minutes each time, 5 times during three days. For data collection, physiological lab levels, immune cells of blood and questionnaires for emotional responses were measured before and after the program. Result: BT of the experiment group was decreased significantly on both of the 1st and the 5th application. PR & BP were decreased significantly on the 1st times, but not 5th times. Hb levels of the experimental group were significantly increased. And emotional responses, vigor and mood scores of the experiment group were significantly increased. B cell & CD19 were increased significantly on the experiment group. Suppressor T cell and NK cell showed significant decrease after the program, but no significant differences between the groups. Conclusion: We have found that the hand reflexology helps the chronic patients to improve physiological.emotional responses and the immune reaction. Through this result, the hand reflexology is effective as a intervention of psychoneuroimmunologic function.

Fast ab/adduction Rate of Articulation Valves in Normal Adults (정상 성인의 조음밸브에 대한 내${\cdot}$외전 비율)

  • Park, Hee-Jun;Han, Ji-Yeon
    • Proceedings of the KSPS conference
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    • 2007.05a
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    • pp.149-151
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    • 2007
  • This study was designed to investigate fast ab/adduction rate of articulation valves in normal adults. The measurement of fast ab/aduction rate has traditionally been used for assessment, diagnosis and therapy in patients who suffered from dysarthria, functional articulation disorders or apraxia of speech. Fast ab/adduction rate shows the documented structural and physiological changes in the central nervous system and the peripheral components of oral and speech production mechanism. Fast ab/adduction rates were obtained from 20 normal subjects by producing the repetition of vocal function (/ihi/), tongue function (/t${\wedge}$/), velopharyngeal function (/m/), and labial function (/p${\wedge}$/). The Aerophone II was used for data recording. The results of finding as follows: average fast ab/adduction rates were vocal function(6.21cps), tongue function(7.42cps), velopharyngeal function(5.23cps), labial function (6.93cps). The results of this study are guidelines of normal diadochokinetic rates. In addition, they can indicate the severity of diseases and evaluation of treatment.

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Cognitive Function in Breast Cancer Patients Receiving Adjuvant Chemotherapy (항암화학요법을 받은 유방암 환자의 인지기능)

  • Kim, Kyung-Hae;Chung, Bok-Yae;Kim, Gyung-Duck;Byun, Hye-Sun;Choi, Eun-Hee;Cho, Eun-Jung
    • Asian Oncology Nursing
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    • v.12 no.1
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    • pp.1-11
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    • 2012
  • Purpose: This study reviewed articles related to breast cancer, cognitive function and chemotherapy available in 4 databases. Methods: The researcher reviewed 32 pieces of literature that were published between January 2001 and November 2011. Results: Within the last decade, several studies have investigated whether adjuvant treatment of breast cancer affects cognitive function. A number of prospective studies have reported inconsistent results regarding whether chemotherapy affects cognitive function. Approximately half of the studies reported subtle cognitive decline in a wide range of domains among some breast cancer patients following chemotherapy, and others did not. Conclusion: Breast cancer patients receiving adjuvant chemotherapy showed the most deterioration and the most persistent decline in cognitive function. Since cognitive impairment is subtle, if evident at all, discrepant findings are due to hormonal, physiological, psychological or temporal confounding variables and differences in study design. Especially, that chemotherapy may impair memory, executive function, attention and visuospatial function in women with breast cancer.

The Effects of Prolonged Sitting in a Cross-legged Posture on Pulmonary Function in Young Adults

  • Son, Sung-Min
    • The Journal of Korean Physical Therapy
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    • v.34 no.1
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    • pp.1-5
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    • 2022
  • Purpose: The impact of prolonged sitting in a cross-legged posture on physiological factors has not been extensively studied. We therefore attempted to evaluate whether prolonged sitting in a cross-legged posture affects pulmonary function in normal young adults. Methods: Twenty-four participants were recruited in this study, and the participants were equally allocated to the normal sitting posture group (NSP group, n=12) or sitting posture with the cross-legs group (SPCL group, n=12). The NSP group sat on chairs without crossing their legs for 30 minutes, and the SPCL group sat on the chair with legs crossed (the right knee on the left knee or the left knee on the right knee) for 30 minutes. The pulmonary function of the subjects was evaluated based on forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FVC/FEV1, and peak expiratory flow (PEF) measured using a spirometer. Results: In the intra-group comparison, the SPCL group showed significant differences in FVC and FEV1 before and after sitting (p<0.05), but no significant differences (p>0.05) were observed in the NSP group. However, there were no significant differences between the two groups in the pulmonary function parameters measured before and after sitting (p>0.05). Conclusion: Our results confirmed that prolonged sitting in a cross-legged posture could have a negative influence on pulmonary function. Therefore, if a sitting position is maintained for a long time, the correct sitting posture should be maintained to prevent musculoskeletal disorders as well as to maintain normal pulmonary function.

Half-Against-Half Multi-class SVM Classify Physiological Response-based Emotion Recognition

  • Vanny, Makara;Ko, Kwang-Eun;Park, Seung-Min;Sim, Kwee-Bo
    • Journal of the Korean Institute of Intelligent Systems
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    • v.23 no.3
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    • pp.262-267
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    • 2013
  • The recognition of human emotional state is one of the most important components for efficient human-human and human- computer interaction. In this paper, four emotions such as fear, disgust, joy, and neutral was a main problem of classifying emotion recognition and an approach of visual-stimuli for eliciting emotion based on physiological signals of skin conductance (SC), skin temperature (SKT), and blood volume pulse (BVP) was used to design the experiment. In order to reach the goal of solving this problem, half-against-half (HAH) multi-class support vector machine (SVM) with Gaussian radial basis function (RBF) kernel was proposed showing the effective techniques to improve the accuracy rate of emotion classification. The experimental results proved that the proposed was an efficient method for solving the emotion recognition problems with the accuracy rate of 90% of neutral, 86.67% of joy, 85% of disgust, and 80% of fear.

How Z-DNA/RNA binding proteins shape homeostasis, inflammation, and immunity

  • Kim, Chun
    • BMB Reports
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    • v.53 no.9
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    • pp.453-457
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    • 2020
  • The right-handed double-helical structure of DNA (B-DNA), which follows the Watson-Crick model, is the canonical form of DNA existing in normal physiological settings. Even though an alternative left-handed structure of DNA (Z-DNA) was discovered in the late 1970s, Z-form nucleic acid has not received much attention from biologists, because it is extremely unstable under physiological conditions, has an ill-defined mechanism of its formation, and has obscure biological functions. The debate about the physiological relevance of Z-DNA was settled only after a class of proteins was found to potentially recognize the Z-form architecture of DNA. Interestingly, these Z-DNA binding proteins can bind not only the left-handed form of DNA but also the equivalent structure of RNA (Z-RNA). The Z-DNA/RNA binding proteins present from viruses to humans function as important regulators of biological processes. In particular, the proteins ADAR1 and ZBP1 are currently being extensively re-evaluated in the field to understand potential roles of the noncanonical Z-conformation of nucleic acids in host immune responses and human disease. Despite a growing body of evidence supporting the biological importance of Z-DNA/RNA, there remain many unanswered principal questions, such as when Z-form nucleic acids arise and how they signal to downstream pathways. Understanding Z-DNA/RNA and the sensors in different pathophysiological conditions will widen our view on the regulation of immune responses and open a new door of opportunity to develop novel types of immunomodulatory therapeutic possibilities.

Physiological Responses-Based Emotion Recognition Using Multi-Class SVM with RBF Kernel (RBF 커널과 다중 클래스 SVM을 이용한 생리적 반응 기반 감정 인식 기술)

  • Vanny, Makara;Ko, Kwang-Eun;Park, Seung-Min;Sim, Kwee-Bo
    • Journal of Institute of Control, Robotics and Systems
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    • v.19 no.4
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    • pp.364-371
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    • 2013
  • Emotion Recognition is one of the important part to develop in human-human and human computer interaction. In this paper, we have focused on the performance of multi-class SVM (Support Vector Machine) with Gaussian RFB (Radial Basis function) kernel, which has been used to solve the problem of emotion recognition from physiological signals and to improve the accuracy of emotion recognition. The experimental paradigm for data acquisition, visual-stimuli of IAPS (International Affective Picture System) are used to induce emotional states, such as fear, disgust, joy, and neutral for each subject. The raw signals of acquisited data are splitted in the trial from each session to pre-process the data. The mean value and standard deviation are employed to extract the data for feature extraction and preparing in the next step of classification. The experimental results are proving that the proposed approach of multi-class SVM with Gaussian RBF kernel with OVO (One-Versus-One) method provided the successful performance, accuracies of classification, which has been performed over these four emotions.

Effects of Polymerized Basic Amino Acids Under 50mer Range of Degree of Polymerization on Physiological and Stimulated Mucin Release from Cultured Hamster Tracheal Surface Epithelial Cells (중합도 50mer 이하의 염기성 아미노산 중합체들이 일차배양 햄스터 기관표면 상피세포에서의 생리적 뮤신유리 및 분비자극 상태에서의 뮤신유리에 미치는 영향)

  • 이충재;이재흔;석정호;허강민
    • Biomolecules & Therapeutics
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    • v.10 no.3
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    • pp.156-164
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    • 2002
  • In the present study, we tried to investigate whether polymerized basic amino acid e.g. poly-L-lysine (PLL) which has the degree of polymerization under 50mer significantly affects the physiological and stimulated mucin release from cultured hamster tracheal surface epithelial cells. Confluent primary hamster tracheal surface epithelial (HTSE) cells were metabolically radiolabeled with $^3{H}$-glucosamine for 24 hr and chased for 30 min in the presence of either PLLs or adenosine triphosphate (ATP) and PLL to assess the effects on basic or ATP-stimulated $^3{H}$-mucin release. Possible cytotoxicities of PLLs were assessed by measuring lactate dehydrogenase (LDH) release from HTSE cel1s during treatment. The results were as follows: PLLs significantly inhibited basic mucin release from cultured HTSE cells in a dose-dependent manner from the range of 46mer to 14mer; PLL 46mer significantly inhibited the stimulated mucin release by ATP from cultured HTSE cells; there was no significant release of LDH from cultured HTSE cells during treatment. We conclude that PLLs inhibit both physiological and stimulated mucin release from airway epithelial cells without significant cytotoxicity and PLL lost its activity under the range of 14mer. This finding suggests that polymer of basic amino acid like PLL might function as a regulator for hypersecretion of mucus manifested in various respiratory diseases.

The Effects of a Stretching Exercise Program in Elderly Women (여성노인에 대한 스트레칭운동프로그램의 효과)

  • 김이순;정인숙;정향미
    • Journal of Korean Academy of Nursing
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    • v.34 no.1
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    • pp.123-131
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    • 2004
  • Purpose: This study was aimed to identify the effects of a ten-week stretching exercise program on physiological, psychological functions, and activities of daily living(ADL) among elderly women. Methods: Using a quasi-experimental design, the experimental group received a ten-week stretching exercise program 3 times a week from March to May in 2002. They were divided into 22 persons in the experimental groups in 2 halls where the program was incorporated, and 22 persons in the control group in 2 halls, where the program wasnot incorporated. Data was analyzed with descriptive statistics, the chi-square test, Fisher's Exact test, and ANCOVA was considered significant as a 2-tailed test. Results: There was a significant improvement in diastolic blood pressure(P=0.023), total cholesterol (P=0.019), triglycerides (P=0.002), spine ROM(P=0.000), trunk and hip-joint ROM(P=0.000), percent of body fat(P=0.039) as physiological functions, depression(P=0.041) as a psychological function, and activities of daily living(P=0.001) in the experimental group compared to the control group. Conclusion: A stretching exercise program showed good effects on improving physiological functions, psychological functions and activities of daily living among the elderly women in a city. Therefore, we recommend this program be utilized as a health promoting program for the elderly in the community.