• Title/Summary/Keyword: Physiological Function

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Analysis of the Effectiveness of Tai Chi Exercise in Elderly (노인에게 적용한 타이치운동의 논문분석)

  • Lee, Hea-Young;Kim, Kum-Ja
    • Journal of muscle and joint health
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    • v.15 no.1
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    • pp.5-23
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    • 2008
  • Purpose: This study aims to conduct a systematic review of the physical, psychosocial and physiological effects of Tai Chi exercise in elderly. Method: 37 articles from Medline search of foreign journals (1966-2006) were surveyed by the key words 'Tai Chi', 'Tai-chi program' and 'Tai-chi and elderly' limiting the range to age 65 or older, choosing clinical trial and randomized controlled trial research in English articles. Four articles were excluded due to methodological study, pilot study and review. The research was analyzed according to health status of the subjects, styles and forms of Tai Chi exercises, factors for physical, psychosocial and physiological measures. Result: A short forming Yang style was commonly used in chronic diseases and health for elderly. Variable outcome measures were used in Tai Chi studies relating to balance, muscle strength, walking and mobility, flexibility and cardiorespiratory function in physical measure, quality of life, depression, self-efficacy, health status, cognition and impact questionnaire in psychosocial measure, lipids, insulin resistance and hormone in physiological measure. Conclusion: Tai Chi exercise appears to have physical and psychosocial benefits and also appears to be safe for elderly and chronic diseases. It is suggested that future studies analyze statistical part of systematic reviews through meta analysis.

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Factors Influencing the Sexual Function of Women with Urinary Incontinence (요실금 여성의 성기능에 영향을 미치는 요인)

  • Kim, Miok
    • Women's Health Nursing
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    • v.19 no.2
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    • pp.108-118
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    • 2013
  • Purpose: Sexual function involves a complex interaction of emotions, body image, and intact physical responses. The purpose of this study was to determine the sexual functioning of women who are incontinent and to identify associated factors. Methods: For this descriptive correlation study, data were collected from 147 women with urinary incontinence. Data were analyzed using t-test, ANOVA, and stepwise multiple regression. Results: Mean scores were 22.39 (sexual dysfunction ${\leq}26.55$) for sexual function, 13.38 (of 63) for depression, and 55.47 (range of score 17~85) for body image. Urinary symptoms and daily life symptoms averaged 36.04 (range of score 20~100) and 16.03 (range of score 8~40). Sexual function had a positive correlation with body image and negative correlation with daily life symptoms. Sexual satisfaction, daily life symptoms, marital satisfaction, and frequency of sexual intercourse were factors affecting sexual function. Conclusion: Study results indicate that urinary incontinence has a negative impact on various aspects of sexual function. Nurses should be aware of the wider consideration that needs to be made in relation to general and sexual quality of life when caring for clients suffering from urological diseases.

Thioredoxin in the Periplasmic Space of Escherichia coli as a Physiological Electron Donor to Periplasmic Thiol Peroxidase, p20

  • Cha, Mee-Kyung;Kim, Il-Han
    • BMB Reports
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    • v.32 no.2
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    • pp.168-172
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    • 1999
  • We previously reported that a novel thiol peroxidase (p20) from Escherichia coli is a distinct periplasmic peroxidase that detoxifies hydroperoxides together with glutathione or thioredoxin. Until now, there was no experimental evidence for the presence of thioredoxin (Trx) in the periplasmic space. In an attempt to confirm the physiological function of p20 as a thiol peroxidase supported by Trx in the periplasmic space, we have purified a Trx activity from the periplasmic space of Escherichia coli and identified the Trx as the same protein as the cytoplasmic Trx. The presence of Trx in the periplasmic space of Escherichia coli suggests that p20 is a unique extracellular Trx-linked thiol peroxidase.

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Study for Variational Characteristics of Brain According to Human Emotion -Human Emotion by Auditory Perception- (감성에 따른 뇌의 변화 특성에 대한 연구 -청각감각에 의한 감성-)

  • Whang, Min-Cheol;Sohn, Jin-Hun;Kim, Chul-Jung
    • Journal of Korean Institute of Industrial Engineers
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    • v.23 no.3
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    • pp.609-619
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    • 1997
  • The concept of human emotion is recently demanded to be imbedded in industrial product and environment for enhancing quality of life. Human emotion is attempted to be qualified and quantified by physiological measurements. EEG variation, one of the physiological measurement, is observed to characterize psychological response in this study. This study is to find function and process of brain according to emotion. Twenty university students participated in this study and experienced positive and negative emotion by auditory stimulus. Delta, theta, alpha and beta waves showed characteristic variation in normalized sense according to positive and negative emotion. Local area showing significant difference between positive and negative emotion decreases with stimulus duration. Delta, theta and beta waves increase with negative emotion while alpha wave does with positive emotion.

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Anaerobic Fermentation and Weight of Hydrated Residue of Dietary Fibers in vitro (In Vitro 법에 의한 식이섬유의 혐기적 발효 및 수화 잔여물의 무게)

  • 이경숙
    • Journal of Nutrition and Health
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    • v.28 no.9
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    • pp.834-845
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    • 1995
  • This study was conducted in order to establish an in vitro method simulating the physiological function of fibers along the large intestine of humans. Commercial fibers including guar gum, apple pectin, citrus pectin, CM-cellulose, alginic acid and $\alpha$-cellulose, and dietary fiber residues obtained from rice bran, barley, soybean, Korea cabbage, apple, tangerine and sea mustard were employed to determine the water-holding capacity, weight of hydrated residue and fiber content after anaerobic fermentation using human fecal inoculum for 24 hours, followed by dialysis under osmotic suction pressure. The weight of hydrated residue in commercial fibers was in the decreasing order of CM-cellulose > alginic acid, $\alpha$-cellulose > apple pectin, citrus pectin > guar gum and that in food fiber residues was in the decreasing order of rice bran, sea mustard > soybean > tangerine, Korean cabbage > barley > apple. It was demonstrated that the larger the weight of hydrated residue was, the more the weight of human stool increased. Consequently this in vitro method can be used as a preceeding test before undertaking animal or human experiment to predict the physiological effects of fiber residues from diverse food samples as well as commercially refined fibers.

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"25-kDa Thiol Peroxidase" (TPx II) Acts as a "Housekeeping" Antioxidant

  • Cha, Mee-Kyung;Kim, II-Han
    • BMB Reports
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    • v.32 no.5
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    • pp.506-510
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    • 1999
  • The newly-found thiol peroxidases (TPx) with a conserved cysteine as the primary site of catalysis are capable of catalyzing the thiol-dependent reduction of peroxides. However, the cellular distributions of the isoforms remain poorly understood. As a first step in understanding the physiological functions of the TPx isoforms, we examined the cellular and tissue distribution of the isoenzymes in various bovine tissues. The tissue distributions of TPx isoenzymes indicate that two types of TPx are widely distributed throughout all of the tested tissues. These two forms are the predominant proteins, with levels of the proteins being quite different from each other. The level of predominant TPx proteins, named type II (TPx II) and type V (TPx V), appeared to be very different with respect to tissue type. The cellular distribution and level of TPx isoenzymes also varied with the types of cells. Immunoblot analysis of the mitochondrial and cytosol fractions from various tissues indicates that TPx III is a unique mitochondrial form. Based on the different tissue and cellular distribution of TPx isoenzymes, we discuss the physiological function of TPx isoenzymes, especially the ubiquitous TPx II.

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Citrobacter amalonatics와 Citrobacter farmari에 의한 perchlorate 환원

  • Nirmala Bardiya
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2003.09a
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    • pp.438-441
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    • 2003
  • The present study reports the novel physiological function of dissimilatory perchlorate reduction by two strains JB101 and JB109 isolated from a sewage treatment facility in Incheon, South Korea. The physiological data of the isolates showed good correspondence with the members of the family Enterobacteriaceae. The partial 16S rRNA and 16S rDNA sequence of strains JB101 and JB109 showed similarity of 99.8% to Citrobacter amalonaticus and 98% to Citrobacter farmari, respectively. The study infers toward possibility of Citrobacter spp. to form an important group of dissimilatory perchlorate reducers within the (equation omitted) subclass of Proteobacteria because the majority of the known. members belong to two monophyletic groups namely Dechloromonas and Dechlorosoma in $\beta$ subclass of Proteobacteria.

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Study on the Seop-Gye's constitution theory for the connection with 'the differentiation of syndromes' and the general body form diagnosis (전신형태 진단과 변증시치의 연계를 위한 엽계의 형태체질론 연구)

  • Kim Gyeong Cheol;Lee Yono Tae;Shin Soon Shik
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.1
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    • pp.22-27
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    • 2004
  • Seop-Gye divided up the constitution's strength and weakness, and so he cured disease by the 'cold and heat'. 'deficiency and excessiveness' means on the basis of the YINㆍYANG of constitution. He classified constitution with pathogenesis grounding in body formal distinction, flesh hardness and softness, face color and form, skin color. Therefore he grasped the rule of constitution connected with physiological function and pathological distinction, applied the rule of constitution in the diagnosis and cure of the chronic & epidemic febrile disease.

Lipophagy: Molecular Mechanisms and Implications in Metabolic Disorders

  • Shin, Dong Wook
    • Molecules and Cells
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    • v.43 no.8
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    • pp.686-693
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    • 2020
  • Autophagy is an intracellular degradation system that breaks down damaged organelles or damaged proteins using intracellular lysosomes. Recent studies have also revealed that various forms of selective autophagy play specific physiological roles under different cellular conditions. Lipid droplets, which are mainly found in adipocytes and hepatocytes, are dynamic organelles that store triglycerides and are critical to health. Lipophagy is a type of selective autophagy that targets lipid droplets and is an essential mechanism for maintaining homeostasis of lipid droplets. However, while processes that regulate lipid droplets such as lipolysis and lipogenesis are relatively well known, the major factors that control lipophagy remain largely unknown. This review introduces the underlying mechanism by which lipophagy is induced and regulated, and the current findings on the major roles of lipophagy in physiological and pathological status. These studies will provide basic insights into the function of lipophagy and may be useful for the development of new therapies for lipophagy dysfunction-related diseases.

SAR of COX-2 Inhibitors (COX-2 억제제의 구조-활성)

  • 권순경
    • Biomolecules & Therapeutics
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    • v.9 no.2
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    • pp.69-78
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    • 2001
  • Cyclooxygenase (COX) is an enzyme, which catalyzes the production of prostaglandins from arachi-donic acid and exists in two isoforms (COX-1 and COX-2). COX-1 is involved in the maintenance of physiological functions such as platelet aggregation, cytoprotection in the stomach and maintenance of normal kidney function. COX-2 is induced significantly in vivo under inflammatory conditions. COX-1 and COX-2 serve different physiological and pathological functions. All commercially available nonsteroidal antiinflammatory drugs (NSAIDS) are inhibitors of both COX-1 and COX-2. Therefore, selective inhibitors of COX-2 may be effective antiinflammatory agents without the ulcerogenic effects associated with current NSAms. Since the mid 1990s, a number of reports have been appeared on the preparation and biological activity of selective COX-2 inhibitors. Recently celecoxib, and rofecoxib, the representative COX-2 inhibitors, are introduced in the drug market. In this paper the relationship of structure-activity for selective COX-2 inhibitors is reviewed.

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