• Title/Summary/Keyword: Physical distance

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Estimation of Linkage Disequilibrium and Effective Population Size using Whole Genome Single Nucleotide Polymorphisms in Hanwoo (한우에서 전장의 유전체 정보를 활용한 연관불평형 및 유효집단크기 추정에 관한 연구)

  • Cho, Chung-Il;Lee, Joon-Ho;Lee, Deuk-Hwan
    • Journal of Life Science
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    • v.22 no.3
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    • pp.366-372
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    • 2012
  • This study was conducted to estimate the extent of linkage disequilibrium (LD) and effective population size using whole genomic single nucleotide polymorphisms (SNP) genotyped by DNA chip in Hanwoo. Using the blood samples of 35 young bulls born from 2005 to 2008 and their progenies (N=253) in a Hanwoo nucleus population collected from Hanwoo Improvement Center, 51,582 SNPs were genotyped using Bovine SNP50 chips. A total of 40,851 SNPs were used in this study after elimination of SNPs with a missing genotyping rate of over 10 percent and monomorphic SNPs (10,730 SNPs). The total autosomal genome length, measured as the sum of the longest syntenic pairs of SNPs by chromosome, was 2,541.6 Mb (Mega base pairs). The average distances of all adjacent pairs by each BTA ranged from 0.55 to 0.74 cM. Decay of LD showed an exponential trend with physical distance. The means of LD ($r^2$) among syntenic SNP pairs were 0.136 at a range of 0-0.1 Mb in physical distance and 0.06 at a range of 0.1-0.2 Mb. When these results were used for Luo's formula, about 2,000 phenotypic records were found to be required to achieve power > 0.9 to detect 5% QTL in the population of Hanwoo. As a result of estimating effective population size by generation in Hanwoo, the estimated effective population size for the current status was 84 heads and the estimate of effective population size for 50 generations of ancestors was 1,150 heads. The average decreasing rates of effective population size by generation were 9.0% at about five generations and 17.3% at the current generation. The main cause of the rapid decrease in effective population size was considered to be the intensive use of a few prominent sires since the application of artificial insemination technology in Korea. To increase and/or sustain the effective population size, the selection of various proven bulls and mating systems that consider genetic diversity are needed.

Voluntary stand-up physical activity enhances endurance exercise capacity in rats

  • Seo, Dae Yun;Lee, Sung Ryul;Kwak, Hyo-Bum;Seo, Kyo Won;McGregor, Robin A;Yeo, Ji Young;Ko, Tae Hee;Bolorerdene, Saranhuu;Kim, Nari;Ko, Kyung Soo;Rhee, Byoung Doo;Han, Jin
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.3
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    • pp.287-295
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    • 2016
  • Involuntary physical activity induced by the avoidance of electrical shock leads to improved endurance exercise capacity in animals. However, it remains unknown whether voluntary stand-up physical activity (SPA) without forced simulating factors improves endurance exercise capacity in animals. We examined the effects of SPA on body weight, cardiac function, and endurance exercise capacity for 12 weeks. Twelve male Sprague-Dawley rats (aged 8 weeks, n=6 per group) were randomly assigned to a control group (CON) or a voluntary SPA group. The rats were induced to perform voluntary SPA (lifting a load equal to their body weight), while the food height (18.0 cm) in cages was increased progressively by 3.5 every 4 weeks until it reached 28.5 cm for 12 weeks. The SPA group showed a lower body weight compared to the CON group, but voluntary SPA did not affect the skeletal muscle and heart weights, food intake, and echocardiography results. Although the SPA group showed higher grip strength, running time, and distance compared to the CON group, the level of irisin, corticosterone, genetic expression of mitochondrial biogenesis, and nuclei numbers were not affected. These findings show that voluntary SPA without any forced stimuli in rats can effectively reduce body weight and enhance endurance exercise capacity, suggesting that it may be an important alternative strategy to enhance endurance exercise capacity.

The analysis of physical features and affective words on facial types of Korean females in twenties (얼굴의 물리적 특징 분석 및 얼굴 관련 감성 어휘 분석 - 20대 한국인 여성 얼굴을 대상으로 -)

  • 박수진;한재현;정찬섭
    • Korean Journal of Cognitive Science
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    • v.13 no.3
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    • pp.1-10
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    • 2002
  • This study was performed to analyze the physical attributes of the faces and affective words on the fares. For analyzing physical attributes inside of a face, 36 facial features were selected and almost of them were the lengths or distance values. For analyzing facial contour 14 points were selected and the lengths from nose-end to them were measured. The values of these features except ratio values normalized by facial vortical length or facial horizontal length because the face size of each person is different. The principal component analysis (PCA) was performed and four major factors were extracted: 'facial contour' component, 'vortical length of eye' component, 'facial width' component, 'eyebrow region' component. We supposed the five-dimensional imaginary space of faces using factor scores of PCA, and selected representative faces evenly in this space. On the other hand, the affective words on faces were collected from magazines and through surveys. The factor analysis and multidimensional scaling method were performed and two orthogonal dimensions for the affections on faces were suggested: babyish-mature and sharp-soft.

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Factors Affecting to the Instrumental Ability of Daily Living(IADL) in the Urban Elderly (도시지역 노인들의 도구적 일상생활 수행능력(IADL)에 영향을 미치는 요인)

  • Lee in hak;Moon Seng ki;Kim kun joo;Park Jae-Young
    • The Journal of Korean Physical Therapy
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    • v.14 no.3
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    • pp.238-272
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    • 2002
  • This study was intended to find out the factors affecting to the IADL, allowing objective assessment of physical function status of increasing elderly populations. The subjects of 635 elderly persons aged over 65 years old who live in Taejon metropolitan city were interviewed during the two-month period from June to July of 2000. The IADL of Older American Resources and Services(OARS), developed in Duke medical college of USA, was interpreted for use. The study results were statistically processed using SPSSWIN(ver 10.0) and conferred the following results: 1. Among the seven items of IADL, the women showed higher rates of 'yes' in items about using the telephone, getting to the places out of walking distance, going shopping for groceries, taking their own medicine while outnumbered by the men only in the item about managing their own money, without significant differences between them in items about preparing their own meals and doing their own housework. 2. In terms of IADL scores, $82.0\%$ of subjects showed the normal range of scores and $18.0\%$ were under the normal range, meaning dysfunction IADL. Specifications of general characteristics revealed that more dysfunctional were the male subjects, the higher age groups who are more than 75 years old, the higher educated groups, the groups who live in nursing homes, the groups without a spouse. 3. Based on daily activities, lower scores of IADL were found in the subjects who don't go out, who don't have recreational activities, who don't attend elderly gatherings in their neighborhood, who don't hold social meetings. Specifications of psychological traits revealed that more dysfunctional were IADL in the subjects who don't feel satisfied with their lives of the past or the present, who have a deep feeling of isolation, and who don't have the will to live. 4. Among 7 items of health habits, only the subjects who don't regular exercise had lower scores of IADL than those who do. According to HPI, the lower HPI, the more dysfunctional. 5. Based on the factors associated with IADL, the odds ratio of the subjects who don't live together with their families were 1.53 times that of the ones who do, who are educated 3.22 times that of the ones who are not, who don't have spouses 2.09 times that of the ones who do, who don't go out 4.35 times that of the ones who frequently go out, who don't recreational activities for an interest 2.64 times that of the ones who do, who don't attend elderly gatherings in their neighborhood 1.47 times that of the ones who do, who don't hold social meetings 2.23 times that of the ones who do, who don't feel satisfied with their present living 1.43 times that of the ones who do, who have a feeling of isolation 1.53times that of the ones who don'1, who have the weak will to live 3.21 times that of the ones who have the strong one, and who don't regular exercise 2.45 times that of the ones who do. 6. Logistic regression analysis of the study results found that such factors are significantly related as the degree of education, with/without spouse, social meetings, the will to live, and regular exercise, and that higher rates of dysfunctional subjects were in the more educated group, in the group without spouse, in the group who don't frequently go out, who don't have social meetings, who have the weak will to live, and who don't exercise.

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Evaluation of Air Ion According to the Distance in Large Flat Park - Focused on Olympic Park in Songpa-gu, Seoul - (대규모 평지형 공원 내 거리별 공기이온 평가 - 서울시 송파구 올림픽공원을 사례로 -)

  • Kim, Jeong Ho;Lee, Sang Hoon;Lee, Myung-Hun;Yoon, Yong Han
    • Korean Journal of Environment and Ecology
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    • v.34 no.5
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    • pp.491-499
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    • 2020
  • Increasing impervious surfaces can cause various physical and mental illnesses as well as further problems like deterioration of the thermal environment and disconnection of the water circulation system in the downtown area. This study is intended to suggest baseline data for the future creation or remodelation of large-scaled urban parks in consideration of human health on the aspect of climate by analyzing air ions condition and correlation analysis between air ions and meteorological elements depending on distances from the center in the urban park. The study site was divided into four types by distances from the center of Olympic Park in Songpa-gu, Seoul, then classified as A and B. After selecting 80 points to record, land coverage and vegetation status were investigated, and then meteorological elements and air ions were measured. First, the green space rate by section is A section Center (90%)> Inner (70%)> Outer-inner (10%) = Outer (10%), B section Center (100%)> Inner (60%)> Outer- In order of inner (30%)> Outer (0%). Second, for weather factors, the temperature was analyzed by Outer (24.18℃) > Outer-inner (22.90℃) > Inner (22.43℃) > Center (21.719℃). For relative humidity, center (46.49%) > Inner (43.36%) > Outer-inner (42.41%) > Outer (38.53%) was analyzed. Third, In the case of cations in the air ions, Outer(435.71ea/㎤) > Outer-inner(415.16ea/㎤) > Inner (389.46ea/㎤) > Center (352.64ea/㎤). In the case of negative ions, Center (569.72ea/㎤) > Inner (499.83ea/㎤) > Outer-inner(410.58ea/㎤) > Outer (292.02ea/㎤). It was analyzed to increase toward Center, and analyzed to decrease with increasing distance from road. For the Air ion index, it was analyzed as Center (1.67) > Inner (1.31) > Outer-inner (1.08) > Outer (0.71). Negative irons was analyzed to increase when its measuring points close to the center and decrease with shortening distance to the road. Fourth, as a result of correlation analysis, positive(+) correlation is negative ions and ion index. These were measured to increase as the recording points closing to the center of the park from the road. The negative(-) correlation is temperature, solar radiation, and positive ions. These increased as getting closer to the road.

Geochemical Characteristics of Soil Solution from the Soil Near Mine Tailing Dumps and the Contamination Assessment in Duckum Mine (토양수의 자구화학특성에 따른 금속폐광산 광미야적장주변 토양오염평가: 덕음광산)

  • 이상훈;정주연
    • Economic and Environmental Geology
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    • v.37 no.1
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    • pp.61-72
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    • 2004
  • The soil samples were collected from the paddy field near the mine tailing dumps in the abandoned Duckum mine in Korea. In the laboratory, the soil solution was extracted from the soil using centrifuge, and analysed for the chemical composition. Physical and chemical soil properties were also analysed. Kaolinite is the main clay minerals in the paddy soil and the CEC value is therefore relatively low. Nearly all soil samples show enrichment in their trace elemental concentrations(Cd, Cu, Pb and Zn) compared with natural background level. Some soil samples exceed the soil remediation intervention values for Cd, Pb and Zn and target value for Cu, when compared with Dutch standard, whereas As, Ni and Cr are in normal range. Lead concentrations in some samples near the mine tailing dumps also exceed the standard for remediation act for agricultural area set by Korean soil conservation law. The trace elemental concentrations are higher in the paddy soil nearer the mine tailing dumps and lower for the samples from distance. Similar trend with distance is found for the soil solution chemistry but the decrease with distance from the mine tailing dumps are sharper than the changes in soil chemistry. Cadmium, Cu and Pb concentrations in the soil solution are very low, ranging from a tenth and hundredths to a maximum of several mg/l, whereas their concentrations in soils are highly enriched for natural background. Most of the trace elements are thought to be either removed by reduced iron sulphides or iron oxides, depending on the redox changes. Geochemical equilibrium modelling indicate the presence of solubility controlling solid phases for Cd and Pb, whereas Zn and Cu might have been controlled by adsorption/desorption processes. Although pollutants migration through solution phase are thought to be limited by adsorption onto various Fe, Mn solid phases, the pollutants exist as easily releasable fractions such as exchangeable site. In this case, the paddy soil would act as pollutant pool, which will supply to plants in situ. whenever the geochemical conditions favour.

A Study on the Regionality of Land-Lease Farming : A Comparative Analysis of the Case Study Areas (임차농(賃借農)의 지역성(地域性)에 관한 연구 -사례지역의 비교분석-)

  • Suh, Chan-Ki
    • Journal of the Korean association of regional geographers
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    • v.3 no.2
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    • pp.121-150
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    • 1997
  • This Study puts the purpose to explicate the regionalities of land-lease farming by a comparative analisis of the five case study areas in Kungpook Province as the agricultural space system of Teagu metropolitan city. For the regional comparative analysis the province was divided into the three zones with the distance from the central city(Teagu): urban fringes, intermediate and remote zone, and then subdivided into the five regions by farming systems : horticulture, rice-farming, and dry-field farming. The data were collected from 77 land-leasing farmers by questionnaire and interview with farm managers in 5 sample villages representing the regionalities of the above five regions respectively. In spite of relatively restricted scope of the research areas, the analytical results appear remarkable regional differences in the characteristics of land-lease farming within a single agricultural space system. In the final analysis the regionalities of the five land-lease farming regions could be described respectively as follows. (1) Koryong-Gun in the inner urban fringe zone : The developing land-lease farming region of commercialized suburban horticulture with medium scale. (2) Songju-Gun in the outer urban fringe zone : The developing land-lease farming region of highly commercialized horticulture with large scale. (3) Uisong-Gun in the intermediate zone : The stagnated land-lease farming region of commercialized rice-farming with large scale. (4) Yongil-Gun in the intermediate zone : The stagnated land-lease farming region of commercializing dry-field farming with medium scale. (5) Ponghwa-Gun in the remote zone : The stagnated and delayed region in commercializing of intermountain dry-field land-lease farming with small scale. These varied regionalities resulted from the diverse spatiality as a complex of spatial orders and localities. The spatial orders in this study are frequently recognizable as a form of distance-decay, and the locality of a region is determined mostly by the its peculiarity of physical and population conditions. In the comparative analysis of the regionalities the degree of commercialization of a region is a most comprehensive and useful frame of reference because it reflects the degree of development of capitalist land-lease farming. Finally these apparent regional differentiations of land-lease farming within a agricultural space system raise the problem of impracticality of the existing uniform logic on the land-lease farming such as "large scale farms share larger part of leased farmland." This problem suggests the urgent need of reappraisal of many aspatial logics and theories on the land-lease farming.

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Effects of Low-power Laser and TDP on the Cutaneous Wound Healing (피부상처 치유에 대한 저에너지레이저와 특정전자파의 효과)

  • Ahn So-Youn;Park Sang-Ock
    • The Journal of Korean Physical Therapy
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    • v.9 no.1
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    • pp.1-18
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    • 1997
  • The purpose of this study is to investigate the effects of the low power Helium Neon-Infra Red(HeNe-IR) laser and the special electromagnetic therapeutic apparatus stimulation, which is usually designated as TDP by using the initial of Tending Diancibo Pu which is the Chinese inscribed with English, on wound healing in rat. The seventy-five Sprague-Dawley adult female and male rats were assigned to the experimental and control groups. Each rat was anesthetized with pentobarbital sodium, and three full-thickness incisions with 12mm length wert made on the back of the half cf the rats and three deep second degree burns were made on the back of the remainder of the rats. From 34 hours after being injured, the rats of the experimental laser group were irradiated with the 157mW electric power HeNe-IR laser for 2 minutes every day and the rats of the experimental TDP group were stimulated with TDP irradiation with the 4km spot distance for 20 minutes every day during the 17 days. The rats were sacrificed and the wound parts of its were incised on the first day, 4th day, 7th day, 10th day and 17th day respectively after the beginning of wound treatment with laser and TDP irradiation. The incised wound parts were processed appropriately for the light microscopic and electron microscopic examination. The length of incised wound was measured with microcaliper before the wound part was incised. There was a significant decrease in the length of the incised wound of the experimental laser and TDP group, compared with that of control group at 4th day, 7th day and 10th day(p<0.01) after surgery. Through the histological examination of the wound site, the more rapid epithelialization and collagen formation in experimental groups were showed, compared with control group. The histological results were analyzed and summarized as the follows; The epidermis begins to be regenerated and the granulation tissue begins to be changed to the mature pattern in the H-E stained incised skin of the laser and TDP treatment group on the 4th day. The epidermis shows the complete regeneration and the granulation tissue in the dermis in mostly to be matured in the laser and TDP treatment group on the 7th day, compared with control group. The chronic inflammatory cells are oberved and the necrosis of the collagen fibers are partially observed in control group on the 10th day. The dermis of the laser and TOP treatment group reveals relatively compactly arranged collgen bundles with the mature collagen fibers on the 10th day. The epidermis and dennis of the laser and TDP group are repaired normally and the hair follicles are well regenerated on the 17th day. The mild edema and the granulation tissue is observed in the dermis of the control groups and the delayed treatment process is observed on the 17th day. The Most of proliferated collagen fibrils are found to be compact and regular in electron micrograph of burn skin of the laser treatment group on the 10th day hut the interstitial eadema and some inflammatory cells are found in the control group. The above results suggest that through the visual and histological examination the epithelized epithelium and the proliferation of the collagen liters in the dermis occur very effectively with the low power laser treatment and the TDP treatment in the incised wound healing and the burn wound healing.

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Changes of Heart Rate During Marathon Running (장거리 (마라톤)선수에서의 전 경기중 심박동수의 변화)

  • Kim, In-Kyo;Lee, Jung-Woo;Hah, Jong-Sik;Ryu, Yun-Hee;Choi, Jung-Ok;Kim, Ki-Ho
    • The Korean Journal of Physiology
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    • v.13 no.1_2
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    • pp.1-12
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    • 1979
  • To evaluate the present status of physical fittness of Korean long distance runners, body fat, pulmonary functions, maximal oxygen intake and oxygen debt were measured in 5 elite marathoners (A group), 6 college student runners (B group) and 3 middle school student runners (C group). After laboratory tests, full course marathon running was performed in 2 elite marathoners during which their heart rates were monitored continuously. The results are summerized as follows: 1) Total body fat in all three groups are in the range of 13-15% of their body weight. 2) In all three groups, average values of various pulmonary functions were within the normal limits, but those of tidal volume were higher and respiratory rate were lower in comparison to normal values. These phenomena may represent respiratory adaptations against training. The average resting oxygen consumptions in A,B and C were $322{\pm}23$, $278{\pm}14$ and $287{\pm}16$m1/min, respectively. 3) In all three groups, resting blood pressures were in the normal range, but the resting heart rate was slightly lower in groups A $(56{\pm}3\;beats/min)$ and B $(64{\pm}2\;beats/min)$ and higher in group C $(82{\pm}9\;beats/min)$ in comparison to normal values. These changes in cardiovascular functions in marathoners may also represent adaptive phenomena. 4) During treadmill running the minute ventilation and oxygen consumption of the runners increased lineally with work load in all three groups. When the oxygen consumption was related to heart rate, it appeared to be a exponential function of the heart rate in all three groups. 5) The average maximal heart rates during maximal work were $196{\pm}3$, $191{\pm}3$ and $196{\pm}5\;beats/min$ for groups A,B and C, respectively. Maximal oxygen intakes were $84.2{\pm}3.3\;ml/min/kg$ in group A, $65.2{\pm}1.1\;ml/min/kg$ in group B and $58.7{\pm}0.4\;ml/min/kg$ in group C. 6) In all three groups, oxygen debts and the rates of recovery of heart rate after treadmill running were lower than those of long ditsance runners reported previously. 7) The 40 km running time in 2 elite marathoners was recorded to be $2^{\circ}42'25'$, and their mean speed was 243 m/min (ranged 218 to 274 m/min). The heart rate appeared to increase lineally with running speed, and the total energy expenditure during 40 km running was approximately 1360.2 Calories. From these it can be speculated that if their heart rates were maintained at 166 beats/min during the full course of marathon running, their records would be arround $2^{\circ}15'$. Based on these results, we may suspect that a successful long distance running is, in part, dependent on the economical utilization of one's aerobic capacity.

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A CYANOACETYLENE STUDY OF THE MOLECULAR DISK IN STAR FORMING REGIONS

  • Chung, H.S.;Kameya, Osamu;Morimoto, Masaki
    • Journal of The Korean Astronomical Society
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    • v.24 no.2
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    • pp.217-271
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    • 1991
  • We have observed dense core around young stellar objects, DR21, S140, Orion-KL, and L1551 using four millimeter-wave transitions of $HC_3N\;J$=4-3, J=5-4, J=10-9, and J=12-11. The spatial distribution of $HC_3N$ emission closely resembles the morphology of the previous CS observations that trace high density gas. These observations reveal the existence of $HC_3N$ dense cores around central IR source, elliptical in shape and almost perpendicular to the CO bipolar outflow axis. Small differences can be explained by that $HC_3N$ molecular line is more optically thin and is seen to be more detailed structure in the neighborhood of central IR sources. In S140 and Orion-KL, massive(${\sim}10\;M_{\odot}$), slowly rotating dense cores lie near at the central IR sources of bipolar outflows. The velocity channel maps of DR21 show that the bipolar outflow gas may have a correlation with the dense core of DR21. We analyzed intensities of the four lines to derive physical conditions in dense core from two methods, LTE and LVG. The column density of $HC_3N$, $N(HC_3N)$, between LTE and LVG calculations agree well with each other. The abundances of $HC_3N$ in each observing source have been estimated using the average values of $n(H_2)$ and $N(HC_3N)$ and assuming the size of dense core. The fractional $HC_3N$ abundances in massive dense cores of DR21, S140, and Orion-KL have a range of $(2-7){\times}10^{-10}$, while that of low mass dense core, L1551, has one order of magnitude greater value of $2{\times}10^{-9}$. This should be considered good agreement with the result by Morris et al.(1976). It may be considered that dense cores of DR21, S140, and Orion-KL may have almost same stage of chemical evolution, and their abundances have a small values relative to that of L1551. The column density $N(HC_3N)$ decreases with increasing distance from the densest part of the cloud, the central infrared source, and have the relation of $N(HC_3N){\varpropto}R^{\alpha}$, where a has a range of 0.65 to 0.89. The values of $n(H_2)$ are not varied with increasing distance from the dense core, and have almost same values. Therefore, it is considered that the dense cores in these regions probably consist of dense clumps in diffuse molecular gas medium, and $n(H_2)$ of each clump is ${\sim}10^5\;cm^{-3}$. Levels in the $T_{ex}$ increases with $n(H_2)$. It is considered that the $HC_3N$ dense cores are not completely thermalized. We examine the relationships between the luminosity of central infrared sources versus mass of the dense cores, and the luminosity of central infrared sources versus molecular hydrogen column density. Luminosities of the central IR sources show good correlation with mass and hydrogen column density of the dense core. Same has been found from CS observations. However, mass and size derived from $HC_3N$ observations are one order of magnitude smaller than those from CS. It can be interpreted that we see more central part of the cloud cores in $NC_3N$ lines than CS lines.

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