• 제목/요약/키워드: Phenolic amides

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Two Phenolic Amides from Cocculus diversifolius

  • Kim, Youn-Chul;Kingston, David G.I
    • 생약학회지
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    • 제26권3호
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    • pp.273-275
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    • 1995
  • Two phenolic amides were isolated from the stem of Cocculus diversifolius (Menispermaceae) and identified as N-trans-feruloyl tyramine and N-trans-feruloyl 3-methyldopamine by spectroscopic methods.

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A New Phenolic Amide from Lycium chinense Miller

  • Han, Song-Hee;Lee, Hyang-Hee;Lee, Ik-Soo;Moon, Young-Hee;Woo, Eun-Rhan
    • Archives of Pharmacal Research
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    • 제25권4호
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    • pp.433-437
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    • 2002
  • A new phenolic amide, dihydro-N-caffeoyltyramine (1) was isolated from the root bark of Lycium chinense Miller, along with known compounds, trans-N-caffeoyltyramine (2), cis-N-caffeoyltyramine (3), and lyoniresinol $3{\alpha}-Ο-{\beta}-D-glucopyranoside$ (4). Their structures were determined by spectroscopic analysis. A NBT superoxide scavenging assay revealed that three phenolic amides showed potent antioxidative activity.

Acetylcholinesterase Inhibitors from the Stem of Zea mays

  • Sim, Jae Young;Kim, Mi Ae;Kim, Myong Jo;Chun, Wanjoo;Kwon, Yongsoo
    • Natural Product Sciences
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    • 제20권1호
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    • pp.13-16
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    • 2014
  • Five compounds were isolated from the stem of Zea mays. Based on spectral data, they were identified as 4-hydroxybenzaldehyde (1), N-trans-p-coumaryl tyramine (2), N-trans-ferulyl tryptamine (3), N-(p-coumaryl) serotonine (4), and N-(p-coumaryl)-tryptamine (5). All isolates were evaluated in vitro for their inhibitory activity on acetylcholinesterase. Among tested compounds, compounds 2 - 5 exhibited acetylcholinesterase inhibitory activity, with $IC_{50}$ values of 125, 60.4, 183.5 and 53.3 ${\mu}M$, respectively. Compound 1 did not show acetylcholinesterase inhibitory activity in the present study.