• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.6
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• pp.573-582
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• 2010

In this paper, X-band transceiver for high resolution wideband SAR systems is designed and fabricated. Also as a technique for enhancing the performance, error compensation algorithm is presented. The transceiver for SAR system is composed of transmitter, receiver, switch matrix and frequency generator. The receiver especially has 2 channel mono-pulse structure for ground moving target indication. The transceiver is able to provide the deramping signal for high resolution mode and select the receive bandwidth for receiving according to the operation mode. The transceiver had over 300 MHz bandwidth in X-band and 13.3 dBm output power which is appropriate to drive the T/R module. The receiver gain and noise figure was 39 dB and 3.96 dB respectively. The receive dynamic range was 30 dB and amplitude imbalance and phase imbalance of I/Q channel was ${\pm}$0.38 dBm and ${\pm}$3.47 degree respectively. The transceiver meets the required electrical performances through the individual tests. This paper shows the pulse error term depending on SAR performance was analyzed and range IRF was enhanced by applying the compensation technique.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.11 no.2
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• pp.71-82
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• 2005

The couple force of the scapular stabilizers for upward rotation that include the upper and lower trapezius, serratus anterior muscles is essential to maintain the stability of shoulder joint. But if there is an imbalance of these muscles, it would occur many problems of shoulder joint. A push-up plus exercise with an unstable support is used in order to increase the muscle activity and stimulate the proprioception of shoulder joint. The purpose of this study was to compare the muscle activity of upper and lower trapezius, serratus anterior muscles and to determine which exercise is more effective when subjects perform push-up plus exercise in the stable support and unstable support. 15 healthy subjects and 15 painful subjects with injury of shoulder joint participated in this study. Surface electromyography data were collected during plus phase of push-up plus exercise. The types of push-up plus exercise were composed of three conditions. Stable type is subjects performed the push-up plus exercise on the fixed support and unstable type 1 is on the sling without shaking and unstable type 2 is on the sling with shaking by tester's manual. The upper and lower trapezius activities of injured group were higher than uninjured group at three measure conditions, but serratus anterior activities were not. The UT/SA ratio of injured group was higher than uninjured group at three measure conditions. The serratus anterior activities were most high at unstable 2 measure in both groups. The UT/SA ratio was most low at unstable 2 measure condition in injured group only. The present result revealed that push-up plus exercise in the unstable support with shaking which took most high serratus anterior activities and most low of UT/SA ratio is optimal cure method that can improve the imbalance of the scapular stabilizer.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.12
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• pp.1097-1106
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• 2011

In this paper, we present design method of wideband single-sideband mixer(SSM) with excellent sideband suppression and carrier suppression. We proposed SSM with 4-band split structure for uniform output flatness. From circuit simulation of this structure using Microwave OfficeTM, we got satisfactory results. We realized a SSM based on this results, then we experimented. The measured results show excellent agreements with the simulated results. We compared with two SSM's(target SSM(M Co. SM0218LC1CDC SSM) and our SSM) as well. The presented SSM is 3.35 times bigger, but sideband suppression is 3 dBc better and carrier suppression is 8 dBc better than those of comparative SSM, respectively.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.3
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• pp.335-342
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• 2012

A high-isolation Ka-band WR-28 waveguide power combiner is designed and implemented using a resistive septum. The waveguide power combiner developed here is an E-plane T-junction type with a TaN resistive septum inserted in a slit of waveguide junction. The fabricated waveguide power combiner shows a return loss better than -20 dB and an insertion loss less than 0.1 dB. Also the measurement shows isolation levels of 20 dB or more almost all over the band and in particular 25 dB or more below 37 GHz. The amplitude and phase imbalance are measured to be less than 0.1 dB and $2.5^{\circ}$, respectively.

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.1587_1588
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• 2009

In this paper, PCB embedded balanced-to-unbalamced duplexer using coupled LC resonator was introduced for low cost dualband WiMax front-end-module application. In order to obtain the function of bandpass filter and balun transformer, proposed duplexer was configured by using magnetically coupled LC resonator. Out-of-band suppression was enhanced by applying two m-Derived transform circuits to obtain transmission zeros at 2GHz and 4.8GHz. In order to reduce the size of embedded duplexer, BaSrTiO3 (BST) composite high Dk RCC film was applied to improve the capacitance density. This high Dk film provided the capacitance density of 12.2 pF/mm2. The simulation results shows that fabricated duplexer had an insertion loss of 2.9dB and 5.5dB and return loss of 15dB and 16dB for 2.5GHz~2.6GHz and 3.5GHz~3.6GHz, respectively. The maximum magnitude and phase imbalance were 0.01dB and 0.17dB, and 1degree and 2degree in its passband, respectively. The out-of-band suppression was observed approximately 29dB and 40dB below 1.9GHz and over 4.5GHz, respectively. It has a volume of 6 mm $\times$ 7 mm $\times$ 0.7 mm (height).

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1551-1556
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• 2014

Background: Transient receptor potential melastatin 8 (TRPM8), a principle membrane receptor involved in calcium ion influx and cell signal transduction, has been found to be up-regulated in some cancer types, including melanomas. Efficiency of menthol, an agonist of TRPM8, in killing melanoma cancer cells has been reported previously, but the mechanisms remain unclear. We here determined whether in vitro cytotoxic effects of menthol on A-375 human malignant melanoma cells might be related to TRPM8 transcript expression. Materials and Methods: The $PrestoBlue^{(R)}$ cell viability assay was used to assess the in vitro cytotoxic effect of menthol after 24h of treatment. RT-PCR was used to quantify TRPM8 transcript expression levels in normal and menthol-treated cells. Cell morphology was observed under inverted phase contrast light microscopy. Results: TRPM8 transcript expression was found at low levels in A-375 cells and down-regulated in a potentially dose-dependent manner by menthol. Menthol exerted in vitro cytotoxic effects on A-375 cells with an $IC_{50}$ value of 11.8 ${\mu}M$, which was at least as effective as 5-fluorouracil ($IC_{50}=120{\mu}M$), a commonly applied chemotherapeutic drug. Menthol showed no dose-dependent cytotoxicity on HeLa cells, a TRPM8 non-expressing cell line. Conclusions: The cytotoxic effects on A-375 cells caused by menthol might be related to reduction of the TRPM8 transcript level. This suggests that menthol might activate TRPM8 to increase cytosolic $Ca^{2+}$ levels, which leads to cytosolic $Ca^{2+}$ imbalance and triggers cell death.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.8
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• pp.35-40
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• 2008

This paper proposes a dual-band balun which is based on Wilkinson power divider. By inserting $\lambda/2$ transmission line between port 2 and 3, this balun shows good matching at all ports and improved isolation. We use matamaterial(CRLH, D-CRLH) structure for a miniaturization of the circuit implementation and dual-band operation at TDMB frequency range(195MHz) and DVB-H frequency range(670MHz). The proposed balun is designed with return loss larger than -12.98dB at all port, and isolation larger than -12.4dB, the amplitude imbalance between output signals less than 0.08dB, also phase differences of outputs less than $2.8^{\circ}$.

• YAKHAK HOEJI
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• v.54 no.5
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• pp.354-361
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• 2010

Glycosphingolipids are structural components of mammalian cell membranes and are involved in essential cellular physiology such as cell-cell interaction, recognition, transmembrane signaling, proliferation and cell death. In this study, the simple quantitative method of monoglycoceramides-containing glucosylceramide and galactosylceramide was developed. The glycosylceramides extracted from culture cells and rat plasma were resolved by TLC, deacylated by SCDase and analyzed by HPLC-fluorescence detector at an excitation wavelength of 340 nm and an emission wavelength of 455 nm. Limit of detection was approximately 0.1 pmol and limit of quantification was about 1 pmol for both monoglycoceramide standards. The recoveries of standard glucosylceramides from intra- and inter-day assays were 113.8 and 88.8% and those of galactosylceramides were 110.7 and 123.9%, respectively. The monoglycoceramide contents of SW-620 cells and rat plasma were $141.5{\pm}5$ pmol/$1{\times}10^6$ cells and $3.9{\pm}0.3{\mu}M$, respectively. The present analytical method provides a reproducible quantification and total content of monoglycoceramide which may be as a potential biomarker for lipid imbalance-related human diseases.

• Physical Therapy Korea
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• v.16 no.3
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• pp.24-31
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• 2009

This study aimed to investigate the effect of differing heel heights on the electromyographic (EMG) activity in vastus medialis (VM) and vastus lateralis (VL) during stair ascending and descending activities. A total of 26 healthy women volunteered to perform stair-ascending and stair-descending tasks with 3 heel heights: barefoot, 3 cm, and 7 cm. The EMG activities of the VM and VL were recorded during the tasks. During the stair ascending and descending tasks, the EMG activities of both VM and VL significantly changed with differing the heel heights (p<.05). Moreover, the EMG activities of VM and VL during the stair ascending task were significantly higher than the corresponding values during the stair-descending task (p<.05). However, there were no significant differences between the VM:VL EMG ratios for the 3 heel heights (p>.05). The VM:VL EMG ratios between the 2 tasks differed significantly in the 7 cm high heel condition (p<.05). Despite an increase in the EMG activities in both VM and VL during stair ascending and descending tasks, there was no change in the relative EMG intensities of VM and VL, which was measured by calculating the VM:VL ratio this result indicates that no VM:VL imbalances were elicited. The relative EMG intensities of VM and VL during stair descent were lower than the corresponding values during the ascent, suggesting that VM and VL may show an imbalance in the eccentric activation during the weight-acceptance phase. This study provides useful information that will facilitate future research on how heel height affects muscle activity around the knee joint.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.3A
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• pp.225-234
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• 2008

Orthogonal Frequency Division Multiplexing (OFDM) systems utilizing direct conversion receiver suffer from frequency selective (FS) and frequency independent (FI) phase and gain imbalances caused by imperfect local oscillator and low pass filter. In this paper, we analyze the impacts of the transmit/receive IQ imbalances on the system and propose the estimation and compensation schemes for those imbalances. The preamble signals coded by Alamouti scheme in the frequency domain could be used in the estimation of relatively large IQ imbalances with FS and FI characteristics and the estimation results are used for the compensation of distortions caused by the FI and FS IQ imbalances. The optimal maximum likelihood (ML) receiver or suboptimal ordered successive interference cancallation (OSIC) receiver utilizing the estimation results show symbol error rate (SER) performance improvement compared to zero-forcing (ZF) technique due to diversity gain inherent in the frequency domain IQ imbalances combined with the frequency selective channels.