• Title/Summary/Keyword: Phase I study

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A Study on Behaviour and Characteristics of Spark Discharge in Spark Ignition System (스파크 점화 시스템의 방전 거동 및 특성에 관한 연구)

  • Lee Myung Jun;Hall Matt;Ezekoye Ofodike A.;Matthews Ron;Chung Sung Sik
    • Transactions of the Korean Society of Automotive Engineers
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    • v.14 no.1
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    • pp.100-108
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    • 2006
  • Time-resolved current and voltage measurements for an inductive automotive spark system were made. Also presented are measurements of the total energy delivered to the spark gap. The measurements were made in air for a range of pressures from 1-18atm, at ambient temperatures. The measured voltage and current characteristics were found to be a function of many ignition parameters; some of these include: spark gap distance, internal resistance of the spark plug and high tension wire, and pressure. The voltages presented were measured either at the top of the spark plug or at the spark gap. The measurements were made at different time resolutions to more accurately resolve the voltage and current behavior throughout the discharge process. This was necessary because the breakdown event occurs on a time scale much shorter than the arc and glow phases. The breakdown, are, and glow voltages were found to be functions of spark plug resistance, gas density, and spark plug gap as expected from the literature. Spark duration was found to decrease as either pressure or gap was increased. The transition from the arc to glow phase is usually distinguished by a sudden rise in the voltage across the gap. At pressures above about 7atm this transition was not observed suggesting that a glow phase was not present. Energy delivered to the gap increased with increasing pressure. The effective resistance of the spark gap during discharge was about twice as large for the glow phase as the arc phase.

Imbalance in the spinal serotonergic pathway induces aggravation of mechanical allodynia and microglial activation in carrageenan inflammation

  • Junxiu Jin;Dong Ho Kang;Jin Jeon;Hyung Gon Lee;Woong Mo Kim;Myung Ha Yoon;Jeong Il Choi
    • The Korean Journal of Pain
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    • v.36 no.1
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    • pp.51-59
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    • 2023
  • Background: This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a rodent pain model of carrageenan inflammation. Methods: Male Sprague-Dawley rats were implanted with an intrathecal (i.t.) catheter to administer the drug. To induce an excess or deficit of 5-HT in the spinal cord, animals were given either three i.t. 5-HT injections at 24-hour intervals or a single i.t. injection of 5,7-dihydroxytryptamine (5,7-DHT) before carrageenan inflammation. Mechanical allodynia was measured using the von Frey test for 0-4 hours (early phase) and 24-28 hours (late phase) after carrageenan injection. The changes in the activation of microglia and astrocyte were examined using immunofluorescence of the dorsal horn of the lumbar spinal cord. Results: Both an excess and a deficit of spinal 5-HT had no or a minimal effect on the intensity of mechanical allodynia during the early phase but prevented the attenuation of mechanical allodynia during the late phase, which was observed in animals not treated with i.t. 5-HT or 5,7-DHT. Animals with an excess or deficit of 5-HT showed stronger activation of microglia, but not astrocyte, during the early and late phases, than did normal animals. Conclusions: Imbalance in the descending 5-HT pathway in the spinal cord could aggravate the mechanical allodynia and enhance the activation of microglia, suggesting that the spinal 5-HT pathway plays an essential role in maintaining the nociceptive processing in balance between facilitation and inhibition in inflammatory pain caused by carrageenan inflammation.

Ecological Studies on Heading of Rice Plant I. The Response to Photoperiod of Major Rice Varieties (수도의 출수생태에 관한 연구 제1보 주요수도 품종의 일장반응)

  • 최경구;장영남;이성춘
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.28 no.2
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    • pp.151-163
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    • 1983
  • This study was conducted to investigate the responses to photoperiod of some Korean rice cultivars at four levels of the day length, 10, 12, 14 and 16 hours. Generally the days to heading were reduced in the short day length. Japonica varieties seemed to have shorter basic vegetative growth phase and, were more sensitive to day length, while Japonica crossed Indica varieties showed longer basic vegetative growth phase and, were less sensitive to day length. All tested varieties could be classified into 19 ecotypes based on the periods of the basic vegetative growth phase and the sensitivity to day length.

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The Effect of Ca Addition on Creep Behavior of As-cast Mg-8.0Zn-1.6Y Alloys with Icosahedral Phase (Icosahedral 상을 갖는 Mg-8Zn-1.6Y 합금의 크리프 거동에 미치는 Ca 첨가 영향)

  • Jung, Young-Gil;Yang, Wonseok;Kim, Shae K.;Lim, Hyunkyu;Oh, Gun-Young;Kim, Youngkyun;Kim, Do Hyang
    • Journal of Korea Foundry Society
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    • v.40 no.2
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    • pp.7-15
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    • 2020
  • The high-temperature stability of Mg-8.0Zn-1.6Y (wt.%) alloys upon the addition of Ca has been investigated by characterizing the ignition temperature, microstructure, tensile and creep properties. The ignition temperature increases with an increase in the Ca content, indicating that an addition of Ca enhances the ignition resistance of the Mg-Zn-Y alloy. The as-cast microstructures of all tested alloys mainly consisted of the dendritic α-Mg matrix and I-phase (Mg3Zn6Y) at the grain boundaries. In the Ca-added Mg-8.0Zn-1.6Y alloys, the Ca2Mg6Zn3 phase forms, with this phase fraction increasing with an increase in the Ca contents. However, a high volume fraction of the Ca2Mg6Zn3 phase rather deteriorates the mechanical properties. Therefore, a moderate amount of Ca element in Mg-8.0Zn-1.6Y alloys is effective for improving the tensile and creep properties of the Mg-Zn-Y alloy. The Mg-8.0Zn-1.6Y-0.3Ca alloy exhibits the highest tensile strength and the lowest creep strain among the alloys investigated in the present study. The creep resistance of Mg-Zn-Y-Ca alloys depends on the selection of the secondary solidification phase; i.e., when Ca2Mg6Zn3 forms in an alloy containing a high level of Ca, the creep resistance deteriorates because Ca2Mg6Zn3 is less stable than the I-phase at a high temperature.

Influence of Xanthan, Emulsification Temperature, and Environmental Stresses on the Preparation of Water-in-Corn Oil Emulsions Droplets Coated by Polyglycerol Polyricinoleate

  • Surh, Jeong-Hee
    • Food Science and Biotechnology
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    • v.18 no.2
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    • pp.299-306
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    • 2009
  • The purpose of this study was to prepare stable water-in-corn oil (W/O) emulsion droplets coated by polyglycerol polyricinoleate (PGPR). W/O emulsions (20 wt% aqueous phase, 80 wt% oil phase containing 8 wt% PGPR) were produced by high pressure homogenization (Emulsions 1), however, appreciable amount of relatively large water droplets (d>$10{\mu}m$) were found. To facilitate droplet disruption, viscosity of each phase was adjusted: (i) increased the viscosity of aqueous phase by adding 0.1 wt% xanthan (Emulsions 2); (ii) decreased the viscosity of oil phase and aqueous phase by heating them separately at $50^{\circ}C$ for 1 hr immediately before emulsification (Emulsions 3). Homogenizing at the elevated temperature clearly led to a smaller water droplet size, whereas xanthan neither improved nor adversely affected on the microstructures of the emulsions. In addition, the Emulsions 3 had good stability to droplet aggregation under shearing stress, thermal processing, and long term storage.

Perception and Practices of Physicians in Addressing the Smokeless Tobacco Epidemic: Findings from Two States in India

  • Panda, Rajmohan;Persai, Divya;Mathur, Manu;Sarkar, Bidyut Kanti
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7237-7241
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    • 2013
  • Background: Smokeless tobacco use in South Asia is believed to be a significant contributor to morbidity and mortality. In India, only a few studies involving health educational intervention by health care providers have demonstrated reduction in smokeless tobacco usage. In the present study we assessed the cessation efforts towards smokeless tobacco by physicians in two high tobacco prevalence states of India. The study also identified opportunities and barriers for integration of tobacco cessation services in routine practices of physicians. Materials and Methods: This mixed method study involved qualitative (phase I) and quantitative research study (phase II). In phase I, 59 in-depth interviews with physicians were conducted. In phase II, a quantitative study conducted among 238 physicians. An inductive approach was followed to analyze qualitative data using ATLAS. Ti software. The Chi-square test was employed to test the association between different variables of interest using SPSS version 17. Results: The majority of physicians related only respiratory problems and cancer with smokeless tobacco. Other major health effects like cardio-vascular problems, oral diseases, and effects on reproductive and neonatal health were recognized only by a few physicians. The age-group of 10-19 years was identified as most vulnerable to smokeless tobacco use. Less than one-third of physicians reported recording smokeless tobacco history of all patients. Findings indicated that less than half of physicians provided information on harmful health effects of smokeless tobacco with regard to specific diseases. Conclusions: The study revealed a low level of knowledge of physicians about harmful effects of tobacco and their suboptimal engagement in tobacco control practices. The study indicates the need of capacity building initiatives to equip physicians with skills in tobacco cessation.

Conjugal Role Structure in the Purchasing Decision Process (구매결정과정에서의 부부의 역할구조)

  • 윤복자
    • Journal of the Korean Home Economics Association
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    • v.19 no.4
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    • pp.73-84
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    • 1981
  • The purpose of this study was to examine the conjugal role structure in the purchasing decision process : problem precognition, information seeking and evaluating, final decision, and actually making the purchase, through a survey of the degree of conjugal involvement. The specific objectives were 1) to examine the conjugal role structure and differences at each phase of the decision process in purchasing of residence and twelve durable household consumer goods, 2) to determine the differences between conjugal role structure in each phase of the purchasing decision process and conjugal demographic factors(number of years married, conjugal education level, conjugal occupation, and income). Questionnaires were given to randomly selected husbands and wives in /seoul I October, 1980. data from the 275 responses were analyzed by percentage, mean, and F-test(analysis of variance). The results are as follows : 1) The conjugal role structure for the purchasing decision process of residence and twelve durable household consumer goods was analyzed by percent. It was found that role structure was specialized by the type of item. for instance, furniture and home appliances were purchased by wives; amusement goods and cars were purchased by husbands' and residence was purchased by joint. However, conjugal role structure in the purchasing decision process differed by phased of process : (1) Wives involvement in the phase of problem recognition was greater than their involvement in information seeking and evaluating, but husbands' involvement a in the phase of information seeking and evaluating was slightly greater than their involvement in problem recognition. (2) Husbands' involvement in the phase of making the final decision was far greater than their involvement I information seeking and evaluating. (3) Wives' involvement in the actually making of the purchase was far greater than their involvement in making the final decision. 2) Only one among conjugal demographic factors was significantly related to conjugal role structure. That, is, conjugal role structure in the purchasing decision process showed that the wives' involvement I making the final decision and in actually making the purchase increased with number of years married.

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A Study on the Two Phase with interleaved Boost Converter (부스트 컨버터의 2상 2중화에 관한 연구)

  • Sin, C.J.;Han, K.H.;Son, Y.I.;Jeong, Y.S.
    • Proceedings of the KIEE Conference
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    • 2008.10c
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    • pp.139-141
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    • 2008
  • In this paper, the authors study the boost converter as a DC-DC converter like a Power supply and describe the investigation result about the two phase with interleaved boost converter which has the same effect that the switching frequency of the solid-state-switch is two times. As a result, the ripple of the input current and output current is better improved.

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Effects of Enzyme Complex on Growth Performance and Nutrient Digestibility in Pigs Weaned at 14 Days of Age

  • Xuan, Z.N.;Kim, J.D.;Lee, J.H.;Han, Y.K.;Park, K.M.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.2
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    • pp.231-236
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    • 2001
  • This study was conducted to investigate the effect of supplemented enzyme complex on growth performance and nutrient digestibility in pigs weaned at 14 days of age. Eighty pigs ($4.02{\pm}0.11kg$ of average body weight) were allotted in a completely randomized block design. Treatments were as follows: 1) control (negative), 2) control (positive, $Kemzyme^{(R)}$), 3) 0.1%, 4) 0.2% and 5) 0.3% of newly developed enzyme complex. Each treatment has 4 replicates with 4 pigs per replicate. During phase I period (d 0 to 14), ADG and ADFI were numerically higher in pigs fed diets supplemented enzyme complex regardless of their inclusion levels compared to pigs fed control (negative) diet. Feed/gain (F/G) was also better in pigs fed enzyme complex diet than that of pigs fed control (negative) diet. In addition, with increasing the inclusion level of enzyme complex, ADG and ADFI were improved. However, there was no significant difference between treatment in all growth parameters. During phase II period (d 15 to 28), ADG, ADFI and F/G showed the same tendency as in phase I period. For overall period (d 0 to 28) ADG was highest in pigs fed diet included 0.2% enzyme complex in all treatments but not significantly different. During phase I period, the digestibilities of all nutrients did not showed any significant difference between treatments. However, pigs fed diet contained enzyme complex and positive control diet (Kemzyme) showed numerically higher nutrient digestibilities in all nutrients than pigs fed negative control diet. During phase II period, data were consistent with those observed in phase I period. Especially, the digestibility of phosphorus was significantly higher in pigs fed diets contained enzyme complex including phytase than pigs fed control (negative and positive) diets (p<0.05). For overall experimental period, fecal or ileal amino acid digestibility were not affected by dietary treatment. Enzyme complex newly developed and used in this study can be possibly recommended as a growth promoter when supplemented in diet for early weaned piglets.

The Effects of the Q-Ray View on Reliability of Assessing a Tooth Status for Dental Hygiene Process (Q-Ray View 활용이 치위생과정을 위한 치아 검사의 신뢰도 향상에 미치는 영향)

  • Oh, Hye-Young;Jung, Hoi-In;Ku, Hye-Min;Kim, Baek-Il
    • Journal of dental hygiene science
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    • v.14 no.4
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    • pp.461-467
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    • 2014
  • The objective of this study was to evaluate the impact of the Q-ray view, a novel optical device on reliability of assessing a tooth status by dental hygiene students in the training for dental hygiene process. Twenty patients were enrolled in this study. Oral examinations were conducted by both seventeen third-year dental hygiene students and a trained faculty member. Traditional visual inspection was performed in phase I and then re-examined with Q-ray view in phase II. Restoration codes and lesion codes for each tooth were recorded separately according to the predefined criteria. As a measure of reliability, percent agreement and Cohen's kappa were determined. Agreements for each intraoral regions and types of lesion and restoration were calculated. Paired t-test and Pearson chi-square test for two proportions were used to compare mean Cohen's kappa and percent agreement at each phase. For the lesion code, mean kappa values of phase II for intraoral regions were significantly greater than that of phase I (p=0.017). For the both of the lesion code and restoration code, percent agreements of phase II for each types of lesion and restoration were significantly greater than that of phase II (p<0.001 and p<0.001, respectively). Especially difference of percent agreements between phase I and II for incipient caries, caries and fracture were significant for the lesion code (p=0.046, p<0.001, and p=0.029, respectively) and for not restored or sealed, tooth-colored restoration were significant for the restoration code (p<0.001 and p=0.011, respectively). The reliability of assessing a tooth status was improved when the Q-ray view used in dental hygiene student with beginner level of expertise. Q-ray view can be a promising device for conducting and educating the dental hygiene process better.