• 제목/요약/키워드: Pharmacological intervention

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Chewing gum as a non-pharmacological alternative for orthodontic pain relief: A randomized clinical trial using an intention-to-treat analysis

  • da Silva Santos, Diego Junior;Capelli, Jonas Jr.
    • The korean journal of orthodontics
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    • v.51 no.5
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    • pp.346-354
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    • 2021
  • Objective: To compare the effectiveness of ibuprofen, acetaminophen, and chewing gum for orthodontic pain relief and to assess if chewing gum can be a non-pharmacological alternative for orthodontic pain relief. Methods: The study enrolled 106 patients of both sexes, aged ≥ 12 years, with body weight > 50 kg, and mild-to-moderate dental crowding in the upper arch. After randomization and allocation concealment, the intervention groups were either administered with ibuprofen (400 mg) or acetaminophen (500 mg) or chewed sugar-free chewing gum immediately after initial archwire placement and every 6 hours for 1 week if the pain persisted. The control group did not receive any pain relief. The pain was assessed on a 100-mm visual analog scale at rest and while biting down at T1 (2 hours), T2 (24 hours), T3 (2 days), T4 (3 days), T5 (7 days), and T6 (21 days). Statistical analyses were performed using the Kruskal-Wallis and post-hoc Mann-Whitney U tests (α = 0.05). Results: The chewing gum group experienced more pain relief than the ibuprofen group at while biting down at T3 (p = 0.04) and at rest at T4 (p < 0.001). The chewing gum group reported more pain relief than the acetaminophen and control groups while biting down at T3 (p = 0.03 and p = 0.0006, respectively) and T4 (both p < 0.001). Conclusions: Chewing gum can be a non-pharmacological alternative for orthodontic pain relief at 2 and 3 days after initial archwire placement.

A Study on the Knowledge Related to Children's Pain of pediatric Nurses According to their Career (아동병동 간호사의 경력에 따른 아동 통증지식에 대한 연구)

  • Choi, Seon-Il;Choe, Myoung-Ae
    • Journal of Korean Biological Nursing Science
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    • v.7 no.1
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    • pp.69-87
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    • 2005
  • Purpose : The purpose of this study was to identify pediatric nurses's knowledge related to children's pain and pediatric nurses' career including educational experience and to examine whether there is a difference of their knowledge according to their career. Method : Subjects of this study was 115 pediatric nurses of one university hospital who understood purpose of this study and accepted to participate in this study. Subjects responded questionnaire by self report. The data were gathered for 7 days during the period from October 20 to October '2:7, 2003. The pediatric nurses' knowledge and attitude survey regarding pain developed by Manworren(2001) was used to identify the knowledge related to children's pain of pediatric nurses. Nurses' career consisted of level of education, presently working ward, duration of experience at clinic, pediatric clinic and presently working ward and educational experience related to children's pain during undergraduate courses, ward orientation and continuing education. Educational experience regarding children's pain was measured by whether they had education related to children's pain during undergraduate courses, ward orientation and continuing education or not and their perception on the contents of education was measured by 5 point Likert type scale. SPSS Windows was used to analyze the data. Scores of the knowledge regarding children's pain and career including educational experience of pediatric nurses were presented as mean and standard deviation. Mean percentage of correct answers responded by the subjects was presented under the category of introduction, assessment, pharmacological and nonpharmacological intervention for children's pain. The difference of scores of the knowledge regarding children's pain according to nurses' career was analyzed using t-test, ANOVA and Tukey as a post hoc. Statistical significance was accepted at the level of p<.05. Result : Pediatric nurses had deficient knowledge related to children's pain on the whole and did not trust pain complaint and underestimated the pain. They were short of concrete practical knowledge about pain assessment and pharmacological and nonpharmacological intervention for children's pain. They were excessively concerned with side effect and addiction of analgesic drugs and had a negative view point on nonpharmacological pain intervention. About 50% of the subjects received education regarding children's pain while their undergraduate courses. The number of nurses who received education regarding children's pain while their undergraduate courses was found to be greater among the recently graduated nurses. In ward orientation and continuing education, only less than 10% of the nurses received education regarding children's pain. Nurses perceived their experienced educational content deficient; experienced educational content consisted of pain introduction, assessment and pharmacological and nonpharmacological intervention for children's pain while their undergraduate course, ward orientation and continuing education. There were no significant differences of the knowledge regarding children's pain of pediatric nurses according to level of education, duration of experience at clinic, pediatric clinic and presently working ward. Scores of the knowledge regarding children's pain of nurses at neonatal ward were significantly greater than those of nurses at pediatric intensive care unit. Scores of the knowledge regarding children's pain of pediatric nurses who received education during their undergraduate course were significantly greater than those who did not receive it during their undergraduate courses. Also scores of the knowledge regarding children's pain of pediatric nurses who received one kind of educational experience were significantly greater than those who had no educational experience. Conclusion : Pediatric nurses had deficient knowledge of children's pain and underestimated the pain of children. Also they were short of concrete practical knowledge on pain assessment and intervention for children's pain.

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Literature View of East-west Nursing on Elderly Sexuality (노년기 성에 대한 동.서 간호학적 고찰)

  • Kim, Kwuy-Bun;Sok, So-Hyune;Oh, Hye-Kyung
    • Journal of East-West Nursing Research
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    • v.5 no.1
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    • pp.75-89
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    • 2000
  • Today, elderly population have tendency to increasing much fast in the world. As aging. elderly people have been changing more in physical, psychological, mental and there is spring to more concerns of health management on old period. But particularly sexuality have been little viewed in health management of elderly people. This is considered that there is bring on complex issues of mental-social, social. cultural, psychological, physical situation with negligence of sexuality on elderly-selves. This research was attempted to provide as basic data for east-west nursing intervention of elderly sexuality through literature view about east-west nursing view and management on elderly sexuality that we attend yet. Conclusively, oriental nursing management, for sexual management of elderly people, is ; 1. Decrease coitus times as physical conditions. 2. If sexual need is present, it don't inhibit painfully. 3. Somebody who have hepatitis, diabetes, heart disease, poor constitution avoids coitus. And western nursing management, for sexual management of elderly people, is ; 1. There is approaching with psychological, pharmacological, technical, surgical area in healthy sexual rehabilitation by Smith(1999). 2. Psychological-Social approaching method by Hooyman & Kiyalk(1996) can be provided for elderly sexuality. As this, concrete nursing intervention can be applied and additional counsel is needed with professional medical-nursing team. Through there understand and percept importance and need of elderly sexuality management on results of literature view, as above, concrete east-west nursing intervention of elderly sexuality will be researched. And research which confirm the meaning, How elderly people, themselves have been perceived, will be processed. This will have more contribution on elderly-oriented nursing intervention without false viewing of elderly sexuality.

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Addition of Myofascial Release Therapy to Therapeutic Exercise for Management of Nonspecific Neck Pain

  • Ha, Yangsun;Hahm, Suk-Chan
    • Journal of The Korean Society of Integrative Medicine
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    • v.9 no.2
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    • pp.35-41
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    • 2021
  • Purpose : It is necessary to demonstrate the effect of non-invasive and non-pharmacological interventions such as manual therapy and therapeutic exercise for the management of nonspecific neck pain. In the present study, we aimed to investigate the efficacy of myofascial release therapy plus therapeutic exercise for disability owing to neck pain and quality of life in individuals with nonspecific neck pain. Methods : Eighteen participants with nonspecific neck pain were randomly allocated to intervention (n=9) and control groups (n=9). The intervention group received a myofascial release therapy for 20 min and performed neck stabilization exercises for 30 min twice a week for 4 weeks. The control group performed neck stabilization exercises for 30 min twice a week for 4 weeks at the same time points as the intervention group. Disability owing to neck pain and quality of life were quantified using the neck disability index (NDI) and the Korean version of the World Health Organization Quality of Life Brief Version (WHOQOL-BREF), respectively. NDI and WHOQOL-BREF were assessed before and after intervention. Results : The disability owing to neck pain significantly changed between the groups over time (total score of NDI, p=.049). There were significant time and group interactions in pain (pain intensity of NDI, p=.035) and concentration (concentration of NDI, p=.049). Personal care, lifting, reading, headaches, work, driving, sleeping, and recreation did not show significant improvement between the groups over time. Total score, overall quality of life and general health, physical health domain, psychological domain, social relationships domain, and environmental domain quantified by WHOQOL-BREF did not show significant improvements between the groups over time. Conclusion : These results suggest the clinical use of myofascial release therapy in addition to therapeutic exercise for the management of nonspecific neck pain. Further studies are needed to generalize the findings of this study.

Effects of Music Therapy on Agitation in Dementia: Systematic Review and Meta-analysis (음악요법이 치매의 초조행동에 미치는 효과: 체계적 문헌고찰 및 메타분석)

  • Kong, Eun-Hi;Park, Myonghwa
    • Korean Journal of Adult Nursing
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    • v.27 no.1
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    • pp.106-116
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    • 2015
  • Purpose: The purpose of this review was to assess the quality and to evaluate the effectiveness of music interventions in reducing agitation in older adults with dementia. Methods: Randomized controlled studies and randomized crossover studies were identified by searching MEDLINE, EMBASE, CINAHL, PsycINFO, AGELINE, Cochrane Central Register of Controlled Trials, Korea Med, Kmbase, RISS, National Assembly Digital Library, KISS, and RICH. Two reviewers independently retrieved articles, extracted data, and assessed the quality of studies. Results: In total, 10 studies were selected from 1095 unique citations. All included studies were conducted in long term care settings. Overall, risk of bias for included studies was low to moderate. The weighted average effect size across studies was -0.39 (95%CI [-0.69, -0.10], p=.009, $I^2=63%$). Music therapy was effective to reduce agitation of the older adults with dementia. Conclusion: Music intervention can be an effective non-pharmacological intervention for the reduction of agitation in dementia. Future studies need to use rigorous research method and to provide description of research methods in greater detail. In addition, future studies are required to explore the effects of music therapy according to severity of agitation and dementia.

The Immediate Effects of Elastic Taping on Center of Pressure and Foot Pressure Distribution

  • Jung-Hee Kim;Jong-Ho Kook;Sang-Mi Lee;Eun-Bin Ko;Song-Yi Han;Yeon-Jeong Kim;Byeong-Jun Min
    • PNF and Movement
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    • v.22 no.1
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    • pp.23-30
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    • 2024
  • Purpose: Ankle instability is a common issue in both daily activities and sports, often leading to recurrent injuries. Elastic taping is a non-pharmacological intervention used to improve ankle stability. This study aimed to investigate the immediate effects of elastic taping on ankle stability, center of pressure (COP) movement, and foot pressure distribution. Methods: A single-group pre-posttest design was employed, with 30 participants included in the study. Plantar pressure and COP parameters were measured before and after the application of elastic taping. Taping was administered in three distinct patterns to enhance ankle stability. Results: Immediate effects of elastic taping were evident in COP parameters. Following taping application, there was a significant decrease in COP total displacement, COP area, and COP velocity. However, no significant changes were observed in plantar pressure parameters. Conclusion: The application of elastic taping in this study demonstrated immediate effects on ankle stability and COP parameters, indicating its potential as a viable intervention for improving balance. Further research with larger sample sizes and long-term follow-up is needed to elucidate the sustained effects of elastic taping on ankle stability.

Effect of Anti-Aging Standard Forest Healing Program With Multiple Visits to a Forest Facility on Cognition in Older Age Patients

  • Jinseok Park;Sheng-Min Wang;Dong Woo Kang;Beom Lee;Hojin Choi
    • Dementia and Neurocognitive Disorders
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    • v.23 no.1
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    • pp.44-53
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    • 2024
  • Background and purpose: The anti-aging standard forest healing program (ASFHP), which uses forest therapy, was reported to be effective in improving psychological, physical, and cognitive functions. However, there are several challenges to directly visiting the forest. This study aimed to investigate the impact of multi-session ASFHP with forest visit on the mental and physical health of the older people with visits to forest facilities and compared them with those of the same program conducted indoors. Methods: Individuals aged over 70 years with concerns about cognitive decline were recruited at dementia relief centers and divided into control and experimental groups. A total of 33 people were administered ASFHP under the supervision of a forest therapy instructor. The control group stayed indoors, while the experimental group visited a forest healing center and repeated the program 20 weeks. Results: The multiple-session ASFHP positively affected cognitive impairment screening test (CIST) total scores (p=0.002), memory (p=0.014), Korean version of the Repeatable Battery for the Assessment of Neuropsychological Status total scores (p<0.001), immediate recall (p=0.001), visuospatial/construction (p<0.001), language (p<0.001), forest healing standard questionnaire total scores (p=0.002), and cognitive function (p=0.019), regardless of location. The forest visits during the ASFHP showed positive effects on orientation (p=0.035), delayed recall (p=0.042), emotional stability (p=0.032), physical activity (p=0.005), and health (p=0.022). The CIST scores of the memory domain were the strongest indicator of the multiple-session ASFHP effects. Conclusions: The 20-week multi-session ASFHP with forest visit showed effects on cognitive improvement and physical and emotional stability compared to indoor education.

Animal Models of Arthritis: Pharmacological Intervention

  • Ryn, Joanne van
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2001.11a
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    • pp.41-76
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    • 2001
  • Rheumatoid arthritis is an incurable chronic inflammatory and destructive arthopathy that affects 1% of the population world-wide. It has substantial personal, social and economic costs. The long-term prognosis is poor: 80 percent of affected patients will become disabled within 20 years after onset of disease. Medical costs of rheumatoid arthritis average ∼$ 6000 (US) per patient (1), Current antirheumatic drugs have limited efficacy and many side effects and more importantly they do not improve the long-term prognosis of rheumatoid arthritis (2). After a decade of few notable advances in therapy, several biological response modifiers that target pathophysiological processes in the disease have now emerged in the clinic. These new drugs are termed biological agents, and although information about their use in the clinic is still limited to short term treatment, they appear to have the ability to modify disease progress. In addition, COX-2 selective agents have now been approved that have comparable efficacy with standard NSAIDs, but fewer gastrointestinal side effects (3). Thus today many more therapeutic options are suddenly open to patients that even five years ago had little hope of relief from chronic pain and inflammation.

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Pediatric Acute Kidney Injury: Focusing on Diagnosis and Management

  • Cho, Myung Hyun
    • Childhood Kidney Diseases
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    • v.24 no.1
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    • pp.19-26
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    • 2020
  • Acute kidney injury (AKI) is common in critically ill children, and is associated with increased mortality and long-term renal sequelae. The definition of pediatric AKI was standardized based on elevation in serum creatinine levels or decrease in urine output; accordingly, epidemiological studies have ensued. Although new biomarkers appear to detect AKI earlier and predict prognosis more accurately than traditional markers, they are not frequently used in clinical setting. There is no validated pharmacological intervention for AKI, so prevention and early detection are the mainstays of treatment. For high risk or early stage AKI patients, optimization of volume status and blood pressure, avoidance of nephrotoxins, and sufficient nutritional support are necessary, and have been demonstrated to be effective in preventing the occurrence of AKI and improving prognosis. Nevertheless, renal replacement therapy is needed when conservative care fails.

A Case of Pneumothorax after Phrenic Nerve Block with Guidance of a Nerve Stimulator

  • Beyaz, Serbulent Gokhan;Tufek, Adnan;Tokgoz, Orhan;Karaman, Haktan
    • The Korean Journal of Pain
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    • v.24 no.2
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    • pp.105-107
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    • 2011
  • Hiccups have more than 100 etiologies. The most common etiology has gastrointestinal origins, related mainly to gastric distention and gastroesophageal reflux disease. Intractable hiccups are rare but may present as a severe symptom of various diseases. Hiccups are mostly treated with non-invasive or pharmacological therapies. If these therapies fail, invasive methods should be used. Here, we present a patient on whom we performed a blockage of the phrenic nerve with the guidance of a nerve stimulator. The patient also had pneumothorax as a complication. Three hours after intervention, a tube thoracostomy was performed. One week later, the patient was cured and discharged from the hospital. In conclusion, a stimulator provides the benefit of localizing the phrenic nerve, which leads to diaphragmatic contractions. Patients with thin necks have more risk of pneumothorax during phrenic nerve location.