• YAKHAK HOEJI
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• v.38 no.6
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• pp.637-645
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• 1994

The effect of various drugs on the stability of the liposomal membrane of phosphatidylcholine and cholesterol was studied, employing the fluorescence self-quenching method. Calcein was entrapped into the phospholipid small unilamellar vesicles and the leakage of the fluorescence probe was monitored on adding the drug to the system. The results of the experiments showed that phenothiazine derivatives, some potent local anesthetics and surface active agents were very effective in inducing the leakage of calcein from the liposome. The leakage-inducing activity of these drug substances has been ascribed to their surface activity and the perturbation of the liposomal membrane by these substances. On the other hand drug substance with low surface activity or without amphiphilic moieties did not show any effect or only small effect on the leakage of calcein from the liposomes. The effect of lipid concentration on the stability of the liposomes was also investigated to show that the higher concentrations of lipid more drug was required to induce the leakage. The effect of surface charges of vesicles was also studied, and the results showed that the charge on the liposomes enhanced the stability of the liposomes against the leakage-inducing activity of these drug substances.

• Wind and Structures
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• v.13 no.3
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• pp.275-292
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• 2010

Wind tunnel experiments were conducted to investigate the wind characteristics in the mountainous valley terrain with 4 simplified valley models and a 1:500 scale model of an existing valley terrain in the simulated atmospheric neutral boundary layer model. Measurements were focused on the mean wind flow and longitudinal turbulence intensity. The relationship between hillside slopes and the velocity speed-up effect were studied. By comparing the preliminary results obtained from the simplified valley model tests and the existing terrain model test, some fundamental information was obtained. The measured results indicate that it is inappropriate to describe the mean wind velocity profiles by a power law using the same roughness exponent along the span wise direction in the mountainous valley terrain. The speed-up effect and the significant change in wind direction of the mean flow were observed, which provide the information necessary for determining the design wind speed such as for a long-span bridge across the valley. The longitudinal turbulence intensity near the ground level is reduced due to the speed-up effect of the valley terrain. However, the local topographic features of a more complicated valley terrain may cause significant perturbation to the general wind field characteristics in the valley.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.26 no.2
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• pp.147-155
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• 2013

In this paper structural analysis of underground electrical power cable structures which is excavated below the surface of the earth in the downtown area is carried out considering the effect of construction sequence. There are many various life-line facilities below the surface of the earth in the downtown area. MPDAP was used for finite element analysis of underground electrical power cable structures. Three typical sections are simulated by finite element models. Unbalanced equilibrium problems may be occurred when conventional finite element procedures were used for simulation of tunnel excavation. Therefore equilibrium perturbation concept was applied to solve these problems. The effects of time-dependent deformations in advancing tunnel excavation are considered in the stages of construction sequences as using the load distribution factor. It is shown that values of maximum displacement of both soil and rock surrounding underground electrical power cable structures obtained by our numerical studies are less than allowable values.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.2
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• pp.171-179
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• 2017

In this paper, microstrip antenna using multi-layer and folded structure for GPS application is presented for aircraft loading. Existing microstrip patch antenna used dielectric of high specific inductive capacity to miniaturize that cause smaller bandwidth and decline of efficiency due to dielectric loss. To compensate the existing flaws, Rogers TMM 10i(dielectric constant=9.8, loss tangent=0.002) is used for multi-layer dielectric miniaturization, and we construct folded radiating element on the surface of the dielectric applying perturbation effect. The antenna is designed in the bandwidth of GPS $L_1$ band, and the size of the antenna's radiating element is $20.3mm{\times}19.93mm$, and it gets 94.2% miniaturized characteristic of basic ${\lambda}/2$ microstrip patch antenna. Also the measured -10 dB bandwidth is 32.3 MHz(2.05%), 3 dB axial ratio bandwidth is 6.7 MHz(0.43%). Measured radiation patterns was maximum gain of 0.56 dBi at x axis polarization, 1.23 dBi at y axis polarization.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.48 no.3
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• pp.200-208
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• 1999

In this paper, the corona discharge is analyzed by Finite Element Method(FEM) combined with Flux-corrected Transport(FCT) algorithm. In the previous papers, Finite Difference Method(FDM) combined with FCT was used. Usually in the FDM, the regionof interest is discretized with structured grids. But to refine local regions with same resolution, much more grids are required for the structured grids than for unstructured grids than for unstructured grids. Therefore, we propose the FEM-FCT method to simulate the corona discharge. The proposed method has good flexibility in model shape and can reduce the computational cost by the local refinement where the physical quantities have steep gradients. Using the proposed method, we study the streamer growth of parallel plate electrodes which is initiated by the low and high perturbation density. We find that the varying the initial density of perturbation has very little effect on the streamer propagation. And the corona discharge of the rod-to-plane electrode is simulated. On the surface of the rod electrode, the high concentration of the electric field gives rise to many number of streamer seeds. The strong axial streamer propagate to the plane electrode. The weaker non-axial streamer repel each other and stop growing more. The results are very similar to those of the papers which used the FDM-FCT method on structured grids. Thus we can conclude that the proposed FEM-FCT method is more efficient than the conventional FDM-FCT method by virtue of the reduction in computational grids number.

• Korean Journal of Food Science and Technology
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• v.21 no.5
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• pp.714-720
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• 1989

Effects of acetylation on conformational changes of glycinin was studied using solvent perturbation, second derivative spectroscopy, near uv circular dichroism spectra and viscosity. Glycinin with purity of more than 93% was used for the experiment. Modification was carried out with acetic anhydride and glycinin with lysine residue modification of 0%, 28%, 65%, 85%, and 95% were used for the experiment. The result of solvent perturbation using some selected perturbants, such as glycerol, ethylene glycol, and dimethyl sulfoxide revealed that acetylation has caused increase In solvent accessibility of tyrosine residues from less than 40% in native protein to more than 70% for 95% acetylated glycinin. This was confirmed by second derivative spectroscopy. Near ultraviolet circular dichroism revealed that the spectra of native and acetylated glycinin were almost identical differing only in intensity and no other useful information could be derived from it. However, in the case of 95% acetylated glycinin the influence of tryptophan on the spectrum was more pronounced Specific viscosity of glycinin also increased by modification, the extent of which depended upon the degree of acetylation. These results supported that acetylation had caused globular conformation of glycinin to be expanded and denatured.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.20 no.4
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• pp.83-94
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• 2021

In this paper, we proposed a microstrip antenna (center frequency 118 MHz) with an omnidirectional radiation pattern that can replace the antennae used in VDB systems in GBAS. First, to obtain an omnidirectional radiation pattern from a microstrip antenna, we constructed a folded antenna. We then designed a miniaturized triple-folded antenna using perturbation effects. Thus we obtained suitable characteristics with a S₁₁ of -13.91dB, -10 dB bandwidth of 1.5 MHz (1.27%) in the center frequency of 118 MHz. Furthermore, in the yz-plane and xy-plane, the component exhibits an omnidirectional radiation pattern, and the size of the antenna achieves miniaturization of 64.2% compared to the reference antenna. Finally, it is suitable as an antenna for VDB systems in GBAS.

• Computers and Concrete
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• v.32 no.1
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• pp.99-117
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• 2023

The crack under the influence of the higher intensities of the stresses grows and the structure gets collapsed with the time when the crack length reaches to critical value. Therefore, the fracture behavior of a structure in terms of stress intensity factors (SIF) becomes important to determine the remaining fracture strength and capacity of material and structure for avoiding catastrophic failure, increasing safety and further improvement in the design. The robustness of the method has been demonstrated by comparing the numerical results with analytical and experimental results of some problems. XFEM is used to model cracks and holes in structures and predict their strength and reliability under service conditions. Further, XFEM is extended with a stochastic method for predicting the sensitivity in terms of output COVs and fracture strength in terms of mean values of stress intensity factors (SIFs) of a structure with discontinuities (cracks and holes) under tensile loading condition with input individual and combined randomness in different system parameters. In stochastic technique, the second order perturbation technique (SOPT) has been used for the predicting the fracture behavior of the structures. The stochastic/perturbation technique is also known as Taylor series expansion method and it provides the reliable results if the input randomness is less than twenty percentage. From the present numerical analysis it is observed that, the crack tip near to the hole is under the influence of the stress concentration and the variational effect of the input random parameters on the crack tip in terms of the SIFs are lesser so the COVs are the less sensitive. The COVs of mixed mode SIFs are the most sensitive for the crack angles (α=45° to 90°) for all the values of c₁ and d₁. The plate with the shorter distance between hole and crack is the most sensitive with all the crack angles but the crack tip which is much nearer to the hole has the highest sensitivity.

• Journal of the Korean Chemical Society
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• v.23 no.2
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• pp.65-74
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• 1979

An effect of the spin-orbit coupling interaction of ligand orbitals on the ground state for octahedral $[Ti(Ⅲ)A_3B_3]$, $ [V(Ⅲ)A_3B_3]$, $ [Fe(Ⅲ)A_3B_3]$ and $ [Ni(Ⅱ)A_3B_3]$ type complexes has been investigated in this work, applying the degenerate perturbation theory. The wave functions are not affected but the energy level splitting for the ground state of these complexes by the spin-orbit coupling interaction of ligand orbitals. The extent of effect on the energy level splitting for the ground state is decreased in order Ti(Ⅲ) > V(Ⅲ) > Fe(Ⅲ).

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.10
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• pp.1184-1192
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• 2004

Experimental investigations were carried out in an atmospheric pressure, optically accessible and laboratory-scale dump combustor operating on methane gas. The objective of this study was to obtain the phase-resolved gas temperatures at different phases of the oscillating pressure cycle during unstable combustion. CARS temperature measurements were made at several spatial locations under lean premixed conditions to get the information on temperature field within the combustor. Also the effect of incomplete fuel-air mixing on phase-resolved temperature fluctuation was investigated. Results including phase-resolved averaged temperature, normalized standard deviation and temperature probability distribution functions (PDFs) were provided in this paper. Temperature PDFs gave an insight on the flame behavior. And strong correlation between phase-resolved temperature profile and pressure cycle was observed. Results of the phase-resolved high temperature gave an additional information on the perturbation of equivalence ratio at flame as well as the effect of mixing quality on NOx emission characteristics.