• 제목/요약/키워드: Persicaria thumbergii

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고마리 지상부의 항산화활성 성분 (Antioxidative Components from the Aerial Parts of Persicaria thunbergii)

  • 이기택;구충환;은재순;신태용;임종필;엄동옥;지옥표;김대근
    • 약학회지
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    • 제45권6호
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    • pp.611-616
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    • 2001
  • The antioxidant activity of Persicaria thunberii (Polygonaceae) was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-pocrylhydrazyl (DPPH) radical. The methanol extract of thunbergii showed strong radical scavenging activity at an I $C_{50}$ concentration of 12.2$\mu\textrm{g}$/ml, and thus fractionated by solvent extraction. The EtOAc soluble fraction was stronger than the others, and was further purified by silica gel and Sephadex LH-20 column chromatography, Antioxidant isorhamnetin, quercetin (2), quercitrin (3) and isoquercitrin (4) were isolated from the EtOAc soluble fraction. And isorhamnetin-3-sulfate (5) was isolated from the n-BuOH fraction. Compounds 2, 3 and 4 were found to have strong antioxidative potency.

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