• 대한소아치과학회지
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• 제26권1호
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• pp.157-161
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• 1999

1. Periphelal odontoma는 매우 드문 질환으로 확진을 위해서는 생검이 필수적이다. 2. Peripheral odontoma는 치은의 종창을 동반하며 서서히 성장하는 임상적 특징을 가진다. 3. 골내 치아종과 마찬가지로 peripheral odontoma의 치료로는 완전한 외과적 절제가 추천되고 예후 또한 양호하다.

• Toxicological Research
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• 제33권2호
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• pp.141-147
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• 2017

Peripheral ameloblastic odontoma is a rare variant of odontogenic tumor occurring in the extraosseous region. The present report describes a spontaneous tumor in male Sprague-Dawley (SD) rats. The clinically confirmed nodule in the right mandibular region was first observed when the rat was 42 weeks and remained until the terminal sacrifice date when the animal was 48 weeks of age. At necropsy, a well demarcated nodule, approximately $2.5{\times}2.0{\times}2.0cm$, protruded from the ventral area of the right mandible. The nodule was not attached to mandibular bone and was not continuous with the normal teeth. Histopathologically, the tumor was characterized by the simultaneous occurrence of an ameloblastomatous component and composite odontoma-like elements within the same tumor. The epithelial portion formed islands or cords resembling the follicle or plexiform pattern typical of ameloblastoma and was surrounded by mesenchymal tissue. Formation of eosinophilic and basophilic hard tissue matrix (dentin and enamel) resembling odontoma was observed in the center of the tumor. Mitotic figures were rare, and areas of cystic degeneration were present. Immunohistochemically, the epithelial component was positive for cytokeratin AE1/AE3 (CK AE1/AE3), and the mesenchymal component and odontoblast-like cells were positive for vimentin, in the same manner as in normal teeth. On the basis of these findings, the tumor was diagnosed as a peripheral ameloblastic odontoma in an extraosseous mandibular region in a SD rat. In the present study, we report the uncommon spontaneous peripheral ameloblastic odontoma in the SD rat. We also discuss here the morphological characteristics, origin, histochemical, and immunohistochemical features for the diagnosis of this tumor.

• 대한소아치과학회지
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• 제39권3호
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• pp.301-305
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• 2012

치아종(odontoma)은 치성기원의 과오종(hamartoma)으로서 법랑질, 상아질, 치수, 백악질 등의 조직으로 구성되어 있고, 조직학적으로 복합치아종과 복잡치아종으로 구분된다. 치아종은 영구치의 맹출을 방해하며 낭종 형성과 인접골 파괴를 유발할 수 있으므로 제거되어야 한다. 제거를 위해서는 적출술을 시행하고 재발은 거의 일어나지 않는다. 악골 외에 존재하는 치아종은 상대적으로 드문 질환으로 악골 내 치아종과 조직학적으로 유사한 특징을 보인다. 본 증례에서는 3세 여자 환아가 하악 우측 구치부 종창을 주소로 본원에 내원하였다. 정기적인 검사 결과 종창의 크기가 증가하였고, 방사선 검사를 통해 병소의 석회화를 확인하여 적출술을 시행하였다. 방사선 검사에서 골내 침식 소견은 관찰되지 않았고, 조직학적 검사를 통해 변연성 치아종으로 확진되었으며, 양호한 치료 결과를 보였기에 보고하는 바이다.

• Imaging Science in Dentistry
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• 제30권1호
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• pp.1-10
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• 2000

Purpose : 1. Retrospectively evaluate the accuracy of tentative diagnosis or impression from the clinico-radio-graphic materials of jaw lesions which showed mixed lesions associated with teeth. 2. To observe the diagnostic importance of the calcified part of the lesions which appear as radiopaque areas. Materials and Methods: 14 cases of jaw lesions which showed mixed lesions associated with teeth were reviewed. These lesions were mostly diagnosed as adenomatoid odontogenic tumors (6 cases) or calcifying odontogenic cysts with (4 cases) or without odontomas (4 cases). The calcified elements of the lesions which demonstrated various sizes and patterns of radiopaque shadows resembled odontoid tissues in some cases but could not be defined in some other cases radiographically. Results : The final histopathologic diagnosis confirmed adenomatoid odontogenic tumors in 4 of the 6 cases. The remaining 2 cases turned out to be odontoma and ameloblastic fibroodontoma. The 4 cases of calcifying odontogenic cysts with odontomas were correct in 3 cases but remaining 1 case was just odontoma. The 4 cases of calcifying odontogenic cysts were proved to be odontogenic keratocyst, calcified peripheral fibroma, unicystic ameloblastoma and squamous cell carcinoma. Conclusion : The diagnostic accuracy of the adenomatoid odontogenic tumors and calcifying odontogenic cysts were high when the lesions show typical appearance. The calcifications which show radiopaque areas could be odontomas or dystrophic calficifations or remnants of bone fragments from resorption.