• 제목/요약/키워드: Periodontal Disease

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치주질환과 당뇨병의 관련성 (An Association of Periodontitis and Diabetes)

  • 원재희;하미나
    • 치위생과학회지
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    • 제14권2호
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    • pp.107-113
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    • 2014
  • 2009년 제 4기 3차년도 국민견강영양조사 자료를 이용하여 우리나라 성인의 치주질환과 당뇨병의 관련성에 대해 평가하고자 하였다. 지역사회치주지수와 혈액검사를 통해 당뇨병을 진단받거나 공복혈당장애에 대한 검사와 당화혈색소 자료가 모두 있는 만 19세 이상의 성인 4,830명이 최종분석대상자가 되었다. 치주질환의 유병률은 성별에 따라서는 남자인 경우, 연령에 따라서는 나이가 많은 경우, 월평균가 수수입과 교육수준이 낮을수록, 흡연 경험이 있고 현재 흡연자일수록, 음주량이 많을수록 높게 나타났다. 당뇨병의 경우 남자인 경우, 나이가 많고, 현재 흡연자일수록, 교육수준과 소득수준이 낮고 음주량과 간식섭취가 많을수록 유병률이 높게 나타났다. 공복혈당수치에 따른 치주질환 유병률은 공복혈당 100 mg/dl 미만은 38.6%, 100 mg/dl 이상은 57.9%로 나타나 100 mg/dl 이상에서 치주질환이 많았다(p<0.0001). 공복혈당장애의 위험은 지역사회치주지수검사에서 CPI가 0~ 2인 그룹을 기준으로 하였을 때 CPI가 3~4인 그룹이 2.18배 높게 나타났다.

치주질환 심도에 따른 조직내 림프구 및 NK 세포의 변화에 관한 면역조직학적 연구 (AN IMMUNOHISTOCHEMICAL STUDY ON THE CHANGES OF LYMPHOCYTE SUBPOPULATIONS AND NK CELLS ACCORDING TO THE SEVERITIES OF THE PERIODONTAL DISEASE)

  • 최호근;권영혁;이만섭
    • Journal of Periodontal and Implant Science
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    • 제23권2호
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    • pp.300-314
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    • 1993
  • Periodontal disease research has been focused on understanding the immunopathologic mechanisms which may operate in the development and maintenance of peiodontal inflammatory changes. Immunologic and inflammatory responses may relate to the etiology and pathogenesis of periodontal disease. In order to research immunopathology of periodontal disease, previous investigators have spent much time on the distribution of lymphocyte subpopulations and NK cells but they have spent less time on the changes of those cells to the periodontal disease severity. The purpose of study was performed to investigate the changes of the distribution of T lymphocytes, B lymphocytes, T lymphocyte subsets, and Natural Killer cells in the gingival epithelium and connective tissue of the periodontal disease with the various clinical parameters including Gingival Index, Sulcular Bleeding Index, and pocket depth. Gingival tissues were obtained from 25 patients with different severity of periodontal disease. Serial cryostat sections displaying a cross section of gingiva were labelled with monoclonal antibody for pan T cells, T cytotoxic/suppressor cells, T helper/inducer cells, pan B cells, and NK cells were develped using an avidin-biotin-peroxidase system. Lymphocyte populations were enumerated in repeatable fields from gingival section. 1. T cells were more increased at grade 1 and 3 than at grade 0 of gingival index (p<0.05). Helper T cells and NK cells were significantly increased at grade 1, 2, 3 than at grade 0(p<0.05). 2. T cells were more decreased at grade 3 and 4 than at grade 1 of sulcular bleeding index (p<0.01, p<0.05). Especially, Natural Killer cells were significantly increased at grade 1, 2, 3, 4 than at grade 0 (p<0.05, p<0.001). 3. The ratios of helper T/suppressor T cells were more decreased at grade 4 than at grade 0 and at grade 4 than at grade 2 of sulcular bleeding index (p<0.05, p<0.05). 4. Helper T cells were significantly decreased at grade II and III than at grade I, however the Natural Killer cells showed a increasing tendency with the increase of the pocket depth, there were no significant differences between each grade of pocket depth. 5. The ratios of helper T/suppressor T cells were tended to be decreased with the increase of the pocket depth, there were no significant differences between each grades of pocket depth. There was a very weak change in the distribution of T lymphocytes, B lymphocytes, T lymphocyte subsets, and Natural Killer cells in the gingival epithelium and connective tissue of the periodontal lesion with the various clinical parameters including gingial index, sulcular bleeding index, and pocket depth. But, the number of T lymphocytes and Natural Killer cells were significantly changed in gingival index and sulcular bleeding index.

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치주염환자에서 Indirect Bonding Technique를 이용한 교정치료 (Orthodontic treatment using indirect bonding technique in periodontitis)

  • 이영석;고은영;김진덕;김송욱;염창엽;김병옥;한경윤
    • Journal of Periodontal and Implant Science
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    • 제28권1호
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    • pp.177-185
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    • 1998
  • 치주염환자에서는 치아의 회전이나 순측경사등으로 인한 상악 정중부 이개 등의 심미적, 기능적 문제들이 자주 수반되어 후속 적인 교정치료를 요하는 경우가 많다. 이러한 경우 보조적인 교정치료로도 치료가 가능한데, 안정된 후방구치에서는 교정력을 가하지 않고 고정 원으로써 작용하게 하고 해당 치아만을 이동시켜야만 한다. 그러나 성인교정에서는 제한점들이 많기 때문에 비교정전문의에게는 섣불리 교정치료를 하기가 어렵다. 더구나 정확히 브라켓을 장착하는 것이 중요한데 간단한 문제는 아니다. Silverman등이 indirect bonding technique을 소개하면서 이런 문제점들을 해결하는데 도움을 주게 되었다. 그후 여러 사람 들에서 다양한 방법들이 소개되었지만 기본적인 원리는 구강 외에서 이상적인 위치에 브라켓을 위치시키고 tray를 이용해서 구강내 치아면에 재현하는 방법이다. 이런 방법을 이용함으로써 molar uprighting, forced eruption, 악교정술시 surgical arch wire 장착, 설측교정술 등에도 쉽게 적용할 수 있다. 이러한 관점에서, 비교정전문의들도 보다 쉽고, 정확하게 브라켓을 위치시킬 수 있는 indirect bonding technique를 이용한다면 보조적인 교정치료 뿐만 아니라 포괄적인 교정치료도 가능하리라 사료된다.

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한국 성인의 체질량지수와 치주질환의 관련성: 제5기 1차년도 국민건강영양조사 (Relationship between body mass index(BMI) and periodontal disease in Korean adult: The fifth Korea National Health and Nutrition Examination Survey(KNHANES V-1))

  • 이민경;진혜정
    • 한국치위생학회지
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    • 제15권6호
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    • pp.991-997
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    • 2015
  • Objectives: The purpose of the study is to investigate the relationship between body mass index(BMI) and periodontal disease in Korean adult from the data of the fifth Korea National Health and Nutrition Examination Survey(KNHANES). Methods: The subjects were 3,309 adults from 25 ro 45 years old in the fifth KNHANES. The subjects were divided into three BMI categories: normal weight 1,549(BMI ${\leq}22.9kg/m^2$), overweight 792(BMI $23.0-25.0kg/m^2$) and obesity 968(BMI ${\geq}25.0kg/m^2$). Periodontal disease was assessed by community periodontal index(CPI) and periodontitis was defined as ${\geq}$ code 3. Results: Increased BMI adults had no significantly higher prevalence of periodontitis than those having normal body weight after adjusting for variables; the odds ratio(OR) was 1.06 in overweight and 1.23 in obesity. BMI and periodontitis had no significant relation to increased age, but the age increase tended to have high odds ratio. Women had a higher OR than men. Conclusions: Through this study, it is necessary to analyze the relationship between the obesity index and periodontitis in the further study.

국민건강보험공단 표본코호트 DB를 이용한 스케일링 보험급여화 전후 실태조사 (Evaluation of national health insurance coverage of periodontal scaling: A nationwide cohort study in Korea)

  • 김영택;이재홍;권혜인;이중석;최정규;김동욱;최성호
    • 대한치과의사협회지
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    • 제54권8호
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    • pp.604-612
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    • 2016
  • The aim of this study was to evaluate the effect of national health insurance coverage of periodontal scaling using the National Health Insurance Service-National Sample Cohort for 2009-2013. After the enforcement of periodontal scaling covered by national health insurance, the number of patients diagnosed with periodontal disease and received treatment, has increased from 35,234 to 99,576 people in the last 4 years. Further, the number of patients who received the treatment of periodontal disease more than once, have also increased to around 69% in 2013 when compared to 2012. Moreover, the number of patients receiving periodontal scaling has been steadily increasing every year. Among the patients who visited hospital for periodontal disease, there has been an increase of 280%. As a result, continuous public relations and long-term research on the effect of periodontal scaling as a prophylactic treatment is necessary.

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Is the relationship between periodontitis and hyperlipidemia mediated by lipoprotein-associated inflammatory mediators?

  • Fentoglu, Ozlem;Bulut, Memduha Tozum;Dogan, Burak;Kirzioglu, Fatma Yesim;Dogan, Esra Sinem Kemer
    • Journal of Periodontal and Implant Science
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    • 제50권3호
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    • pp.135-145
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    • 2020
  • Purpose: The aim of this study was to evaluate the serum levels of oxidized low-density lipoprotein (oxLDL), anti-oxLDL, and myeloperoxidase (MPO) in hyperlipidemic patients with periodontal disease. Methods: This study included 123 patients with hyperlipidemia categorized based on metabolic control as mild to moderate (H1) (n=66) or poor (H2) (n=57), as well as systemically healthy controls (C) (n=68). Serum levels of lipids, oxLDL, anti-oxLDL, and MPO were evaluated, along with clinical periodontal parameters. Results: The percentage of bleeding on probing (BOP%) and the clinical attachment level were significantly higher in the H2 group than in the C group. Patients with hyperlipidemia had a relatively high risk of developing periodontal disease. The oxLDL and anti-oxLDL levels were higher in H2 patients with periodontitis than in the control or H1 patients with periodontitis. In the H1 and H2 groups, the ratio of total cholesterol to high-density lipoprotein was significantly correlated with gingival index, BOP%, and oxLDL levels. Conclusions: Our findings indicate that the lipoprotein-associated inflammatory mediators of oxLDL, anti-oxLDL, and MPO may play an important role in the relationship between periodontal disease and hyperlipidemia.

만성치주염 환자에 대한 저용량 독시싸이클린의 임상적 효과 (Clinical Effect of the Subantimicrobial Dose of Doxycycline ( SDD ) on the Chronic Periodontitis)

  • 김윤식;백정원;김창성;최성호;김종관
    • Journal of Periodontal and Implant Science
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    • 제32권2호
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    • pp.415-428
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    • 2002
  • Periodontal disease is a complex infectious disease caused by bacteria in the oral mucosa, which results in gingival inflammation, breakdown of periodontal tissues, bone resorption, and finally tooth loss. Mechanical plaque control methods-scaling and root planing are effective methods to stop the progression of such periodontal disease. It was reported that subantimicrobial dose of doxycycline(SDD) regimen could improve clinical conditions of periodontal tissues without causing the overgrowth of opportunistic organisms that was a typical antibiotic side effect. Therefore pharmacological therapy, used in conjunction with mechanical therapy could be considered a useful treatment modality in the treatment of chronic periodontal disease. In this study, 30 patients diagnosed as moderate to advanced chronic periodontitis were divided into 2 groups. In this double-blind, placebo-controlled study, the patients were administered 20mg doxycycline capsule or placebo capsule b.i.d. for 4months, after scaling and root planing. Clinical parameters-bleeding on probing, pocket depth and clinical attachment level were compared and evaluated between these groups at periods of first visit, 1 month, 2 months, 3 months, 4 months. The results were as follows ; 1. In case of moderate periodontitis, pocket depth showed significant reduction after treatment in both the control & experiment groups, when compared with the baseline values(p<0.01), but in case of advanced periodontitis, only the experiment group showed significant reduction after treatment when compared with the baseline values(p<0.05). Statistically significant reduction in pocket depth was observed in the experiment group compared to the control group(p<0.05). 2. In case of moderate periodontitis, clinical attachment level showed significant reduction after treatment in both the control & experiment groups, when compared with the baseline values(p<0.01), but in case of advanced periodontitis, only the experiment group showed significant reduction after treatment when compared with the baseline values(p<0.05). Statistically significant reduction in clinical attachment level was observed in the experiment group compared to the control group(p<0.05). 3. Bleeding on probing improved after treatment in both the groups. In case of moderate periodontitis, the experiment group showed statistically significant reduction of bleeding on probing when compared with the control group at 1 and 4 months after treatment(p<0.05). In case of advanced periodontitis, treatment resulted in statistically significant reduction of bleeding on probing in both the groups(p<0.05). These results indicate that the use of subantimicrobial dose of doxycycline is a useful supplement to mechanical treatment for periodontal patients in ameliorating the clinical parameters such as periodontal pocket, attachment level, and bleeding on probing.

한국 청소년의 치아우식증과 치주질환에 대한 예방행위 경험 관련요인 (Related factors of preventive behavior experiences toward dental caries and periodontal disease in Korean adolescents)

  • 박신영;한여정;류소연
    • 한국치위생학회지
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    • 제16권3호
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    • pp.417-426
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    • 2016
  • Objectives: The objective of the study was to investigate the related factors of preventive behavior experience toward dental caries and periodontal disease in Korean adolescents. Methods: The study subjects were 72,060 adolescents in 800 schools who completed 2014 Korean Youth Risk Behavior Web-based survey. Dependent variables included general characteristics of the subjects, oral health behavior, and oral disease experience. The experience rate of sealant and scaling showed the prevention behavior of dental caries and periodontal disease. Data were analyzed by IBM SPSS statistics 20.0. Results: The experience rate of sealant accounted for 26.9%. The experience of sealant was related with gender, school, maternal education level, economic status, vigorous physical activity, smoking, usual stress, fruit consumption, milk consumption, soda consumption, snack consumption, tooth brushing, oral health education experience, periodontal bleeding and pain, mucosal disorders, and bad breath. The experience rate of scaling was 22.6%. The experience of scaling was related with gender, school, city division, learning achievement, maternal education level, economic status, residential type, vigorous physical activity, usual stress, fruit consumption, milk consumption, tooth brushing, oral health education experience, periodontal bleeding and pain, mucosal disorders, and bad breath. Conclusions: To expand preventive oral health behavior in the adolescents, it is necessary to support the systematic policy making and monetary establishment in the future.

The Relationship between Hormone Replacement Therapy and Periodontal Disease in Postmenopausal Women

  • Ahn, Eunsuk;Lee, Yunhee
    • 치위생과학회지
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    • 제18권1호
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    • pp.9-17
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    • 2018
  • The purpose of this study was to investigate the relationship between hormone replacement therapy (HRT) and periodontal disease in postmenopausal women using data from the 4th and 5th Korea National Health and Nutrition Examination Survey. A total of 5,482 postmenopausal women aged 45~75 years were included as study subjects in the final analysis. The HRT group comprised 1,035 postmenopausal women who had received HRT for at least one month, and the non-HRT group comprised 4,447 postmenopausal women who did not receive HRT. The chi-square test was used to confirm the bivariate relationship between the variables. Multinomial logistic regression analysis was used to adjust for covariance (age, education, family income, body mass index, age of menopause, alcohol, smoking, dental visit <1 per year, use of oral care products, and frequency of tooth brushing per day). After adjusting for all covariates, HRT was found to be associated with periodontal disease. In particular, the relationship between HRT and periodontal disease was more evident in older women and women younger than 45 years of menopausal age. The relationship between HRT and periodontal disease was stronger in women who brushed their teeth less than 3 times per day, women without regular oral examination, and women who did not use oral hygiene products. The results of this study confirmed the importance of actively considering hormone therapy when determining policy recommendations for postmenopausal women. Especially, health programs such as HRT, regular dental examination, and oral care are needed for older women who have undergone premature menopause.