• 한국안전학회지
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• 제16권2호
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• pp.110-116
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• 2001

The objective of the Maintenance Rule (MR) is to require monitoring of the overall continuing effectiveness of licensee maintenance programs to ensure that the safety related and certain nonsafety-related SSCs are capable of performing their intended functions. In Korea, as risk informed applications and regulation become active, the necessity of Performance Based Regulation (PBR) has increased. The objective of this article is to study the effectiveness of MR based on performance and feasibility of MR adoption at Korean Nuclear Power Plants (NPPs) for effective maintenance and regulation.

• 대한수의학회지
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• 제59권1호
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• pp.47-49
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• 2019

A renal oncocytoma was diagnosed in an 8-year-old female Maltese dog with a history of renal cysts. Tumor cells were not detected until six months after observation of renal cysts. Nephrectomy was performed to treat the neoplasia. Tumor-like masses with numerous nodules were observed in the inner surface of cysts present in the caudal part of the left kidney. Histologically, the tumor consisted of cells with abundant eosinophilic cytoplasm. The diagnosis was based on histological features, periodic acid-Schiff reaction, and immunohistochemical cytokeratin staining. Based on a literature review, this is the first canine renal oncocytoma case reported in Korea.

• East Asian Economic Review
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• 제24권4호
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• pp.337-348
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• 2020

Although the WTO has fulfilled several key tasks it was set up to do - providing periodic reviews of members' trade policies, resolving disputes, supporting negotiations - with the notable exceptions of the Trade Facilitation and Information Technology agreements, WTO members have not been able to negotiate new rules on "bread and butter" trade policies. The importance of doing so was illustrated by the COVID-19 pandemic which saw widespread uncoordinated recourse to trade policy instruments. This paper highlights four reforms that would bolster the effectiveness of the WTO as a forum for trade cooperation: (1) improving collection and reporting of information on trade-related policies; (2) supporting analysis-informed deliberation to establish a common understanding of the need and scope for cooperation in specific policy areas; (3) putting in place a stronger multilateral governance framework for plurilateral cooperation between groups of WTO members; and (4) reestablishing an effective dispute settlement system.

• 무역학회지
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• 제44권2호
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• pp.189-202
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• 2019

The Harmonized System comprises about 5,000 commodity groups; each identified by a six digit code, arranged in a legal and logical structure and is supported by well-defined rules to achieve uniform classification. This study reviews the appropriateness of Korea Customs Service and Tax Tribunal's customs classification decisions concerning the interpretation and application of the Harmonized System for certain ITA goods. Korea Customs Service had classified arbitrary and had not applied in dubio pro reo principle. This paper finds that 57% of Korea Customs Service's classification decisions have erred. Korea government need to take measures to secure uniform interpretation of the HS and its periodic updating in light of developments in technology and changes in trade patterns. This paper suggest to amend customs law and regulation concerning classification committee.

• 신경정신의학
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• 제57권4호
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• pp.276-286
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• 2018

Circadian rhythm is a periodic and continuous change in physiological, behavioral, and mental characteristics that occurs in most organisms on the Earth, because the Earth rotates in a 24-hour cycle. The circadian system regulates daily rhythms of physiology and behavior, such as the sleep/wake cycle, body temperature, hormonal secretion, and mood. The influence of circadian rhythm is very powerful, but limited research has addressed its effects. However, many recent studies have shown that circadian dysregulation may play an important role in the pathogenesis of bipolar disorder. This review study examined current and noteworthy studies, including the authors' own works, and proposes a possible clinical application of bipolar disorder based on evidence that circadian rhythm dysregulation in bipolar disorder may be a key pathogenetic mechanism.

• Molecules and Cells
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• 제46권10호
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• pp.573-578
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• 2023

The mammalian skin contains hair follicles, which are epidermal appendages that undergo periodic cycles and exhibit mini-organ features, such as discrete stem cell compartments and different cellular components. Wound-induced hair follicle neogenesis (WIHN) is the remarkable ability to regenerate hair follicles after large-scale wounding and occurs in several adult mammals. WIHN is comparable to embryonic hair follicle development in its processes. Researchers are beginning to identify the stem cells that, in response to wounding, develop into neogenic hair follicles, as well as to understand the functions of immune cells, mesenchymal cells, and several signaling pathways that are essential for this process. WIHN represents a promising therapeutic approach to the reprogramming of cellular states for promoting hair follicle regeneration and preventing scar formation. In the scope of this review, we investigate the contribution of several cell types and molecular mechanisms to WIHN.

• 지구물리와물리탐사
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• 제18권3호
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• pp.133-142
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• 2015

지구대기압력이 지각에 변위를 일으키는 현상은 오래 전부터 인식되었으며, 근래의 측지-측량, 특히 우주측지에서 이의 정확한 산정이 필요하게 되었다. 육지에서의 대기 하중에 의한 변형은 주어진 대기압 분포와 하중함수로부터 바로 계산할 수 있으며, 해양에 근접한 지역에서는 근사적인 모델이 사용되고 있다. 지구 대기대순환의 변화와 계절별 지구 양반구에서의 대기압의 분포의 변화들이 각각 지구자전속도 변화와 극운동의 가장 큰 요인으로 알려져 있으며, 바람과 대기압의 변화는 여러 주기영역에서 지구상의 지점들의 좌표의 섭동 및 지구자전상태의 큰 변화 요인이 되고 있다. 본 연구에서는 이와 같은 현상들을 기술하며 관련된 이론과 모델들을 요약하고, 또한 한반도를 지나가는 가상적인 태풍에 의한 효과를 예시하였다. 마지막으로 관련된 몇몇 문제점들과 향후 연구방향을 논의하였다.

• Restorative Dentistry and Endodontics
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• 제20권2호
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• pp.843-855
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• 1995

Occupational Dentistry was introduced in Korea about 70 years ago. During the colonial period occupied by Japan till 1945, there were few documents about industrial dentistry, furthermore most cases of occupational diseases and accidents might have been concealed intentionally by the colonial government. After being an independent country, several dentists made efforts to set up 'Preventive Dentistry for Workers' performing specific oral health surveys, even though which were stopped by Korean War. In 1960s' and 1970s', some investigations of oral status were carried out intermittently for specific small groups;white-collar workers, mentally retarded person, buddhist monks and crews of ocean liners. At the same time there was important study in Korean history of occupational dentistry, which was 'a comparison of the oral hygiene conditions in the female workers of a spinning factory at intervals of 30 years.' In 1980s', young researchers began to give attention to erosion of the teeth due to sulphuric acid in the acid-related industry and dental caries due to sugar and flour in the sweets industry. After being democratic labor union movement activated in 1987, hidden and suppressed occupational diseases under the military dictatorship were exposed and flushed in the newspapers. It was shocking for all people that 15-year old boy had been dead due to mercury intoxication after 3-month employment in 1988. In 1990s', the activity for studying oral status of workers in their workplaces was launched and 'Occupational Accidents and Diseases in Oral and Maxillofacial Field' was published. And also The Korean Association of Occupationl Dentistry was established. Oral health examination of workers at the time of employment and of workers exposed to 5 special chemicals at the time of routine special health examination was adopted in 1992, and epocally oral health examination was also included in periodic routine examination of workers' health in 1995. So, occupational dentistry in Korea should cope with the changing needs of working environment and the altering scheme of health examination.

• Journal of Nutrition and Health
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• 제46권3호
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• pp.218-225
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• 2013

Although the functional ingredient has been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, the levels of scientific evidence and consistency of the results might vary according to emerging data. Therefore, periodic re-evaluation may be needed for some functional ingredients. In this study, we re-evaluated scientific evidence for the antioxidant activity of coenzyme Q10 as a functional ingredient in health functional food. Literature searches were conducted using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2010 with the search term of coenzyme Q10 in combination with antioxidant. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 33 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between coenzyme Q10 and antioxidant activity. Among 33 studies, significant effects for antioxidant activities were reported in 22 studies and their daily intake amount was 60 to 300 mg. Based on this systematic review, we concluded that there was possible evidence to support a relation between coenzyme Q10 intake and antioxidant activities. However, because inconsistent results have recently been reported, future studies should be monitored.

• 한국의학물리학회지:의학물리
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• 제30권4호
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• pp.75-88
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• 2019

Diagnostic reference level (DRL) is employed to optimize the radiation doses of patients. The objective of this study is to review the DRLs for interventional procedures in Korea and abroad. Literature review was performed to investigate radiation dose index and measurement methodology commonly used in DRL determination. Dose area product (DAP) and fluoroscopy time within each major procedure category were systematically abstracted and analyzed. A wide variation was found in the radiation dose. The DAP values and fluoroscopy times ranged 0.01-3,081 Gy·㎠ and 2-16,878 seconds for all the interventional procedures, 8.5-1,679 Gy·㎠ and 32-5,775 seconds for the transcatheter arterial chemoembolization (TACE), and 0.1-686 Gy·㎠ and 16-6,636 seconds for the transfemoral cerebral angiography (TFCA), respectively. The DRL values of the DAP and fluoroscopy time were 238 Gy·㎠ and 1,224 seconds for the TACE and 189 Gy·㎠ and 686 seconds for the TFCA, respectively. Generally, the DRLs of Korea were lower than those of other developed countries, except for the percutaneous transluminal angioplasty with stent in arteries of the lower extremity (LE PTA and stent), aneurysm coil embolization, and Hickman insertion procedures. The wide variation in the radiation doses of the different procedures suggests that more attention must be paid to reduce unnecessary radiation exposure from medical imaging. Furthermore, periodic nationwide survey of medical radiation exposures is necessary to optimize the patient dose for radiation protection, which will ultimately contribute to patient dose reduction and radiological safety.