• Title/Summary/Keyword: Periodic Change

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Nasal Continuous Airway Pressure Titration Unmasks Periodic Limb Movements in Obstructive Sleep Apnea Syndrome (폐쇄성 수면무호흡증에서 지속적 상기도 양압술에 따른 주기성 사지운동증의 표출)

  • Park, Doo-Heum;Jeong, Do-Un
    • Sleep Medicine and Psychophysiology
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    • v.5 no.1
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    • pp.103-110
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    • 1998
  • Objectives : High co-morbidity of periodic limb movements during sleep(PLMS) and obstructive sleep apnea syndrome(OSAS) is well known and their incidences tend to increase in the elderly. Previous studies have inconsistently rep0l1ed increase or no change of periodic limb movement index(PLMI) by nasal continuous positive airway pressure(CPAP) in OSAS without analyzing possible variables affecting PLMI. We attempted to examine PLMI change evoked during CPAP titration and also factors affecting it in OSAS. Methods : Twenty-nine OSAS patients(M:F=26:3, mean age: $51.6{\pm}10.6\;yrs$) without other sleep disorders except for PLMS were selected, based on the nocturnal (baseline) polysomnograhy. Another night of noctumal polysomnography was performed for CPAP pressure titration. We compared between those two nights PLMI, mean and lowest $SaO_2$, and sleep variables. We also calculated PLMI differences between baseline and CPAP nights, named as delta PLMI (value of CPAP night PLMI minus value of baseline night PLMI). Correlations were calculated between delta PLMI and factors such as age, body mass index, applied CPAP pressure, baseline night values of respiratory disturbance index, mean and lowest $SaO_2$, and sleep parameter differences between baseline and CPAP nights. Results : Decrease of RDI(p<.01) and increase in mean and lowest $SaO_2$ (p<.05, p<.01) were observed during CPAP night. No sleep parameters showed significant change except for the decrease of total stage 1 sleep%(p<.01) during CPAP night. Ten out of 29 patients showed PLMI increase, while the other 19 patients showed either no change(n=14) or even PLMI decrease(n=5) during CPAP night. The 10 patients showing PLMI increase during CPAP night showed a significant positive correlation between delta PLMI and baseline night RDI(p<.05), which meant that PLMI increase was found to be more prominent in higher RDI patients than in lower RDI ones. There were no significant correlations between delta PLMI and other factors in the other 19 patients. Conclusions : We suggest that during the baseline night PLMS would have been underscored and/or masked due to the overlapping of PLMS and apneas/hypopneas or the arousals induced by apneas/hypopneas. Despite its still unknown mechanism, the CPAP application may unmask PLMS and increase PLMI in a subgroup of OSAS patients. It needs to be evaluated further whether the chronic CPAP use sustains the above finding.

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Climate Change Impacts on Agricultural Water in Nakdong-river Watershed (기후변화에 따른 낙동강 유역 농업용수 영향 분석)

  • Jee, Yong-Keun;Lee, Jin-Hee;Kim, Sang-Dan
    • Journal of The Korean Society of Agricultural Engineers
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    • v.54 no.3
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    • pp.149-157
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    • 2012
  • For the systemic management and planning of future agricultural water resources, deriving and analyzing the various results of climate change are necessary to respond the uncertainties of climate change. This study assessed the impact of climate change on the rainfall, temperature, and agricultural water requirement targeting in the Nakdong-river's basin periodically according to socioeconomic driving factors under the scenarios A1B, A2 and B1 of the Special Report on Emission Scenarios (SRES) through the various IPCC GCMs. As a result of future rainfall change (2011~2100), increasing or decreasing tendency of rainfall change for future periods did not show a clear trend for three rainfall observatories, Daegu, Busan and Gumi. The characteristics of the temperature change consistently show a tendency to increase, and in the case of Daegu observatory, high temperature growth was shown. Especially, it was increased by 93.3 % in the period of future3 (2071~2100) for A2 scenario. According to the scenario and periodic analyses on the agricultural water demand, which was thought to be dependent on rainfall and temperature, the agricultural water demand increased at almost every period except during the Period Future1 (2011~2040) with different increase sizes, and the scenario-specific results were shown to be similar. As for areas, the agricultural water demand showed more changes in the sub-basin located by the branch of Nakdong-river than at the mainstream of the River.

Development of Apparatus for Measuring Hydraulic Resistance of Sea Ground Considering Tidal Current Flow (조류 흐름을 고려한 해양지반 수리저항성능 실험기 개발)

  • Kang, Kyoung-O;Jeong, Hyun-Chel;Kim, Young-Sang
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.09a
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    • pp.1366-1369
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    • 2010
  • Along with the increasing need of sea development, the hydraulic stability of seabed structure on a soft seafloor ground is becoming an issue in the course of seaside development recently. However, the movement and hydraulic resistance or hydraulic stability of seafloor ground are mutually coupled with various phenomena, and there has been no clear proof for the issue, which makes it difficult to forecast. Furthermore, most researches are focused on hydraulic variables and the conditions of marine external force, while there have been few researches into the assessment in consideration of the type of a seafloor ground and the geotechnical characteristics. In addition, according to the periodic change of the flow direction, possible changes in hydraulic resistance performance of the seafloor deserves all the recognition. But there is no way to measure the hydraulic unstability of the sea ground due to tidal flow quantitatively. In this study, conventional hydraulic resistance measurement apparatus was improved to consider direction change of the current flow. Various artificial clayey soil specimens were made from Kaolinite and Jumunjin standard sand and hydraulic resistance tests were performed by changing the flow direction to validate the effect of the direction change on the scour of the seafloor.

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Numerical Study on the change of Absorption Characteristics by Change of Flow pattern in the Vertical Falling Film Absorber (수직 액막 흡수관의 유동변화에 따른 흡수성능 변화에 관한 해석적 연구)

  • Kim, Jung-Kuk;Cho, Keum-Nam
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.90-96
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    • 2003
  • Numerical analyses have been performed to obtain the absorption heat and mass transfer coefficients and the absorption mass flux from a falling film of LiBr solution. In the present study, the behavior of laminar-wavy falling film in the vertical absorber was studied analytically and experimentally. The change of absorption performance on mean film thickness, wave amplitude, wave celerity was analysed. The heat and mass transfer equations are solved simultaneously to give the temperature and concentration variations at the LiBr solution/refrigeration vapor interface and at the wall. Effects of uniform film, wavy film and film Reynolds number on the heat and mass transfer coefficients have been estimated. The analytical results of the uniform and wavy falling film in the bare tube was higher than experimental result for $Rd_{t}<100$. The absorption performance showed the maximum at the wavy film by the insert device(spring).

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Analysis of Recent 30-year Climate Characteristics by Natural Geography (자연지형 구분에 의한 최근 30년간 기후특성 분석)

  • Ryu, Yeon-Soo;Park, Mi-Lan;Kim, Jin-Wook;Joo, Hye-Jin
    • 한국태양에너지학회:학술대회논문집
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    • 2011.04a
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    • pp.256-262
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    • 2011
  • Environmental pollution by Using of a fossil fuel, a reckless and growth-oriented development since the Industrial Revolution has caused global change of environment. An issue largest among this is a climate change. A global mean temperature since 19th century has climbed up $0.4{\sim}0.8^{\circ}C$. After The Kyoto Protocol regarding a greenhouse gas reduction goal took effect, be situations that decrease of greenhouse gas was acutely required. Interest of utilization of the new & renewable energy is increasing every day. This study shows that at first divided a country to nine range by natural geography, and second executed Meteorological data analysis of recent 30 years considering level of significance by nine range. The results of this study are that in heating load calculation of building, periodic temperature data management is required because facility capacity and cost are affected greatly by outdoor temperature, and temperature by climate range needs consideration of pertinent area. Lastly, ground temperature was assumed of the weather in region, the ground and soil.

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Design of a Hybrid Controller to Eliminate the Force Ripple in the Linear Motor (선형 모터에서 힘리플 제거를 위한 Hybrid 제어기의 설계)

  • Kim, Kyong-Chon;Kim, Jung-Jae;Choi, Young-Man;Gweon, Dae-Gab
    • Journal of the Semiconductor & Display Technology
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    • v.7 no.1
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    • pp.17-22
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    • 2008
  • The proposed hybrid controller consists of PID controller, feedforward controller and RLSE (Recursive Least Square Estimating) adaptive controller to compensate the force ripple that is periodic function of position in a linear motor. The modeling of force ripple is divided into the current-dependent and current-independent components. The current independent components never change as the current into the linear motor changes. On the other hand, the current-dependent components change as current varies when the velocity and load of the linear motor change. The proposed controller can compensate both force ripples. The feedforward controller compensates the current-independent components and the RLSE adaptive controller compensates the current-dependents components. We verified the performance of the controller by simulation and experiments.

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An Integrated Modeling Approach for Predicting Potential Epidemics of Bacterial Blossom Blight in Kiwifruit under Climate Change

  • Kim, Kwang-Hyung;Koh, Young Jin
    • The Plant Pathology Journal
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    • v.35 no.5
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    • pp.459-472
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    • 2019
  • The increasing variation in climatic conditions under climate change directly influences plant-microbe interactions. To account for as many variables as possible that may play critical roles in such interactions, the use of an integrated modeling approach is necessary. Here, we report for the first time a local impact assessment and adaptation study of future epidemics of kiwifruit bacterial blossom blight (KBB) in Jeonnam province, Korea, using an integrated modeling approach. This study included a series of models that integrated both the phenological responses of kiwifruit and the epidemiological responses of KBB to climatic factors with a 1 km resolution, under the RCP8.5 climate change scenario. Our results indicate that the area suitable for kiwifruit cultivation in Jeonnam province will increase and that the flowering date of kiwifruit will occur increasingly earlier, mainly due to the warming climate. Future epidemics of KBB during the predicted flowering periods were estimated using the Pss-KBB Risk Model over the predicted suitable cultivation regions, and we found location-specific, periodic outbreaks of KBB in the province through 2100. Here, we further suggest a potential, scientifically-informed, long-term adaptation strategy using a cultivar of kiwifruit with a different maturity period to relieve the pressures of future KBB risk. Our results clearly show one of the possible options for a local impact assessment and adaptation study using multiple models in an integrated way.

Effects of temporary and periodic emersion on the growth of Fucus spiralis and Pelvetia canaliculata germlings

  • Kim, Bo-Yeon;Park, Seo-Kyoung;Norton, Trevor A.;Choi, Han-Gil
    • ALGAE
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    • v.26 no.2
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    • pp.193-200
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    • 2011
  • The stress tolerance ability of Pelvetia canaliculata (L.) Dcne. Et Thur. and Fucus spiralis L. to temporary and periodic emersion stress was examined in order to test the following hypotheses: The upper shore alga, P. canaliculata is more tolerant to desiccation than F. spiralis in the germling stage and the former outgrows the latter under desiccation stress; Germling stress tolerance of the two species is age-specific; Crowding of germlings protects them from desiccation, irrespective of the species involved. Germling growth of the two species was retarded with increasing exposure period and was age-specific, as they were air-exposed at an earlier stage. After 16 days, the length of Pelvetia germlings was similar between 2-day-old germlings (125-140 ${\mu}m$) and 7-day-old germlings (134-140 ${\mu}m$), which were air-exposed during the same period (0, 6, 12, 24, 48, and 72 h) at the two different ages. However, Fucus germlings were significantly larger at 7-day-old germlings (211-277 ${\mu}m$) than at 2-day-old germlings (184-278 ${\mu}m$), especially in the treatments of 48 and 72 h. These results indicate that Fuscus grow faster than Pelvetia and that the growth response of germlings to temporary emersion stress is more sensitive in Fucus than that in Pelvetia. Growth of germlings of both species was reduced with increasing density under favorable growth conditions (submerged control and 6 h / 12 h exposure treatments) in the periodic air-exposed experiments using tidal tanks, but was enhanced under severe emersion stress conditions. P. canaliculata showed better growth at 6 h exposure treatment than that of the control, under continuous submergence, indicating that Pelvetia germlings require a periodic exposure period. Fucus germlings always grew faster than those of Pelvetia and did best in mixed cultures, whereas Pelvetia did least well when mixed with Fucus germlings. The adverse effects of F. spiralis on P. canaliculata were greater than those of Pelvetia cohorts. The outcome of interspecific competition between F. spiralis and P. canaliculata gemlings was slightly altered by exposure period but not to such an extent as to change the outcome.

Development of Wastewater Treatment and Recycle Technology Using a Tubular Ceramic Ultrafiltration Membrane 1, Effect of Periodic Backflushing (관형 세라믹 한외여과막을 사용한 폐수처리 및 재활용기술개발 : 1, 주기적 역세척 효과)

  • 박진용
    • Membrane Journal
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    • v.9 no.3
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    • pp.178-184
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    • 1999
  • A periodic backflushing was performed to reduce the membrane fouling of ultrafiltration for wastewater, and the effect and the optimum condition were investigated in this study. The alumina¬ceramic tubular membrane with pore size of 0.02${\mu}m$ was used for the wastewater treated by coagulation and sedimentation from two paper plants, of which A plant made toilet paper by recycling milk paper cartons and B plant recycled corrugated cardboards. And the effect of periodic backflushing to membrane fouling and quality of permeate were studied with a constant backflushing time of 3 sec. As results of measuring SS, TDS, and COD of source and permeate, the rejection rate of SS showed the highest value at the backflushing period of 15 see, which was the shortest time in these experiments, in case of waste¬water discharged from A plant. However, the rejection rate of COD had the highest value at the period of 30 sec for wastewater from both A and B plant. Then, the rejection rate of TDS was almost same at 30 and 60 sec for A plant wastewater, and the highest at 60 see for B plant. The effect of periodic back¬flushing to membrane fouling was investigated by change of permeate flux according to operating time. The permeate flux decreased slowly at the operation with backflushing, and was higher compared with that without backflushing in both case of A and B wastewater. But, the optimum period with the highest flux of A wastewater was different from that of B, because SS and COD of A was higher than those of Band TDS of B was higher than that of A.

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Effect of Extracellular Potassium on Delayed Rectifier Potassium Channel Proteins of KCNQ3 and KCNQ5 in Familial Hypokalemic Periodic Paralysis (가족성 저칼륨성 주기성 마비에서 세포외 칼륨농도가 지연성 정류형 채널을 형성하는 KCNQ3와 KCNQ5 단백질에 미치는 효과)

  • Kim, Sung-Jo;Kim, Dong-Hyun;Kim, June-Bum
    • Journal of Life Science
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    • v.19 no.10
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    • pp.1484-1488
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    • 2009
  • Familial hypokalemic periodic paralysis (HOKPP) is an autosomal dominant muscle disorder characterized by episodic attacks of muscle weakness with concomitant hypokalemia. Mutations in either a calcium channel gene (CACNA1S) or a sodium channel gene (SCN4A) have been shown to be responsible for this disease. The combination of sarcolemmal depolarization and hypokalemia has been attributed to abnormalities of the potassium conductance governing the resting membrane potential. To understand the pathophysiology of this disorder, we examined both mRNA and protein levels of delayed rectifier potassium channel genes, KCNQ3 and KCNQ5, in skeletal muscle fibers biopsied from patients with HOKOur results showed an increase in the cytoplasmic level of KCNQ3 protein in patients' cells exposed to 50 mM external concentration of potassium. However, mRNA levels of both channel genes did not show significant change in the same condition. Our results suggest that long term exposure of skeletal muscle cells in HOKPP patients to high extracellular potassium alters the KCNQ3 localization, which could possibly hinder the normal function of this channel protein. These findings may provide an important clue to understanding the molecular mechanism of familial hypokalemic periodic paralysis.