• Title/Summary/Keyword: Percent improvement

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Quality Characters and Identification of Breeding Materials in Malting Barley (맥주보리 품질 관련 형질과 고품질 육종소재 탐색)

  • 오세관;현종내;서득용;서세정
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.48 no.3
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    • pp.184-190
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    • 2003
  • Germplasms and breeding lines of malting barley at National Yeongnam Agricultural Experiment Station (NYAES) were evaluated for malting barley quality improvement. Among the numerous malting barley quality parameters, the mean of protein content was 12.3% between 10.7% to 14.0% and range of the $\beta$-glucan content was from 3.5% to 5.8%, the mean was 4.6 percent. The length of acrospire, non-germination rate, friability, the speed of filtration, extract yield, kolbach index, diastatic power were significantly different between the individual varieties, however the other traits were not significantly different. The results of correlation analysis among 15 quality parameters showed significant positive correlation between crude protein content and malt protein content. However, other quality parameters such as sugar content, fiablity, extract yield, and kolbach index had negative correlation with crude protein content. Therefore, crude protein content could be one of the major factors that deteriorate quality. The varieties of Viva, Nishino-chikara, Kinukei 9, Kinukei 12, Sacheon 6 and Jinyangbori that showed over the 80% in extract yield and the higher diastatic power, will be used by crossing parents for improve the quality of malting barley.

A Study on the Effective Adjustment of Building Insulation Performance and the Application of the Night Purge Ventilation System for Low Energy Building Design (저에너지건축물 설계를 위한 건축물 단열성능의 효과적 조정과 야간외기 도입에 따른 에너지 시뮬레이션 연구)

  • Yun, Hyun-Su;Lee, Tae-Kyu;Kim, Jeong-Uk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.10
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    • pp.625-632
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    • 2018
  • This study was done to reduce total energy demand based on resource shortage problems and to provide improvement points for more efficient adjustment of the high insulation standards for saving energy in Korea. The demand sensitivity was fully considered by varying the slope of each building. The energy performance of the building was maximized by the introduction of outdoor air at night. A final low-energy building model was developed with the two measures combined, and the short-term operation of the night-fuzzy ventilation system was simulated. The result showed a reduction of about 6 to 7 percent compared to the base model. The results could have many implications in terms of the need to conduct demand sensitivity analyses in architectural design.

Compatibility of DOAS and Conventional Point Monitoring System Through an Evaluation of Bias Structures Using Long-term Measurement Data in Seoul (장기관측자료를 이용한 DOAS와 점측정 분석시스템의 바이어스 구조에 대한 평가)

  • 김기현;김민영
    • Journal of Korean Society for Atmospheric Environment
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    • v.17 no.5
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    • pp.395-405
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    • 2001
  • To make an assessment of the compatibility between DOAS and conventional point monitoring system (MCSAM-2: MS2), we investigated the concentrations of three criteria pollutants which include S $O_2$, N $O_2$, and $O_3$from a national monitoring station in Seoul during the periods of June 1999~August 2000. The average concentration values for the whole study period derived from hourly concentration data sets of those three species indicated that the mean differences between the two methods can be approximated as 18%. When the bias structure of two systems was evaluated through the computation of percent difference(PD) between the two such as ( $C_{DOAS}$- $C_{conventional}$ $C_{DOAS}$*100, differences between the two systems appeared to be quite systematic among different compounds. While the mode of bias peaked at 0~20% or 20~40% in terms of PD values, the cause of such positive bias mainly arised from generally enhanced concentration values of DOAS system. The structure of bias among different species was further assessed through linear regression analysis. Results of the analysis indicated that the dominant portions of differences observed from two monitoring systems can be accounted for by the systematic differences in their spanning and zeroing systems. S $O_2$(MS2)=0.6385 S $O_2$(DOAS)+2.0985($r^2$=0.7894) N $O_2$(MS2)=0.6548 N $O_2$(DOAS)+7.437($r^2$=0.7687) $O_3$(MS2)=1.0359 $O_3$(DOAS)-7.7885($r^2$=0.7944) The findings of slope values at around 0.64~0.65 from two species suggest that DOAS should respond more sensitively in upper bound concentration range. The offset values apart from zero indicate that more deliberate comparison needs to be made between these monitoring systems. However, based on the existence of strong correlations from at least 8,000 data points for each species of comparison, we were able to conclude that the compatibility of two monitoring systems is highly significant. With the improvement of calibration techniques for the DOAS system. its applicability for routine monitoring of airborne pollutant species is expected to be quite extendable.

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Introduction of the Basin Sewerage Plan in Japan through Case Studies of the Lake Biwa Sewerage System (비와호 유역하수도 사례분석을 통한 일본 유역하수도계획의 소개)

  • Han, Mideok;Park, Bae Kyung;Park, Ji Hyoung;Kim, Yong Seok;Rhew, Doug Hee
    • Journal of Korean Society of Environmental Engineers
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    • v.37 no.9
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    • pp.533-541
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    • 2015
  • We investigate the Japan's Master Plan of Comprehensive Sewerage System (JMPS) and Lake Biwa basin sewerage and suggest future development direction of the Watershed Sewerage System Maintenance Plan in Korea enforced on February 2, 2013. The JMPS is designed for compliance with the environmental standard for water quality under the Environmental Policy Act. The effluent standards applied in the master plan of Lake Biwa's Sewerage Plan for the Lake Biwa is tougher than the national standards. Therefore the Lake Biwa Baisn Sewerage System was the first in Japan to adopt facilities that perform advanced treatment for nitrogen and phosphorus removal. BOD, SS, T-N and T-P concentrations of discharge water of sewage are 0.9, 0.6, 5.5, 0.06 mg/L, respectively. Especially removal efficiency for BOD is 99.5 percent. It is necessary to study the diversification of the evaluation criteria, cost minimization approach, subsidy system improvement, economic concept of discharge load adjustment system and establishment of basin sewerage concept for the development of the basin sewerage plan in Korea.

Clinical Outcome of Turkish Metastatic Breast Cancer Patients with Currently Available Treatment Modalities - Single Center Experience

  • Cabuk, Devrim;Basaran, Gul;Teomete, Mehmet;Dane, Faysal;Korkmaz, Taner;Seber, Selcuk;Telli, Ferhat;Yumuk, Perran Fulden;Turhal, Serdar
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.117-122
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    • 2014
  • Background: Breast cancer is the most common malignancy and the second leading cause of cancer-related death among women in the developed countries. Despite advances in screening, improved local therapies and adjuvant systemic treatments, median survival of metastatic breast cancer patients (MBC) is in the range of 2-3 years at most. We aimed to investigate whether the prognostic factors and therapeutic responses of our Turkish patients are similar to those in the literature. Materials and Methods: We reviewed the medical records of MBC patients who had been treated in our institution between 1999-2009 and analyzed their clinicopathological features and survival outcomes retrospectively Results: A hundred and sixty patients were included. Median age was 47 (23-82), median follow up was 24 (2-186) months. At the time of diagnosis 59% of patients were under the age of 50 and 46% were postmenopausal. The majority (37%) had multiple sites of metastases. Forty percent received endocrine therapy and 40% chemotherapy as first line metastatic treatment. Thirty (20%) patients were treated with molecular targeting agents like trastuzumab, lapatinib and sunitinib, frequently combined with a chemotherapy agent. Five-year overall survival (OS) was 32% and median OS was 38 months for the whole group. Five year progression free survival (PFS) was 10% and median PFS was 10 months. Menopausal status, hormone receptor expression and disease free status had a significant impact on overall survival in the multivariate analysis (p 0.018, p 0.018 and p:0.003, respectively). Conclusions: All our patients were treated with the modern oncologic therapies recommended by the international guidelines. From our data, MBC patients live up to 3-4 years, indicating that further improvement beyond that requires development of new treatment modalities. The survival outcomes of our patients were consistent with the data reported in the literature.

Improvement of duty rate of Meteor Burst communication with Buried Antenna (매설형 안테나를 이용한 유성 버스트 통신의 도통율 개선)

  • 김병철;이영철;김기채
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1999.05a
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    • pp.254-260
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    • 1999
  • Meteor Burst Communication can provide effective and economical means of communication where long distance VHF NLOS data transmission is needed; often ranges more than 1000 km. It has been, however, so far considered unsuitable for short distance application because of phenomenal decrease in burst durations, which leads to decreation of total duty rate of the system. This paper extensively analyzes characteristics of shot distance MB(Meteor Burst) path and shows the low duty rate may be improved by increasing burst rate through adapting antenna beam width to cover entire hot-spot region in the space and, by compensating effective burst length through cutting down man-made noises introduced by antenna. Based on the analysis, we are developed a small-opening-cavity antenna, especially designed for short distance MB path. In operation, the antenna is to be buried under ground surface so as to improve directivity and reduces noise introduction. The antenna exhibits power gain of 3 dB with 90 degree beam width and thus enables to illuminate entire hot-spot regions with the elevation angle of 8-90 degree which is the case of transmission less than 100 km. Directivity horizontal to earth surface is suppressed to minimum which enables to cut man-made noises from near-by sources down to more than 3 dB from the level reported with conventional 4 element Yagi. A series of experiments performed on 100 km MB paths have conformed that, with the antenna installed at receiving site, the burst rate and duration time have been noticed to increase by 10 and 20 percent respectively from the values obtained by conventional 4-element Yagi antenna under same testing condition.

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The Effects Analysis and Model Project on Speed Management in Commerical Area Street (상업지역 생활도로 속도관리 시범운영 및 효과분석)

  • Shim, Kywan-Bho;Heo, Nak-Won
    • International Journal of Highway Engineering
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    • v.13 no.1
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    • pp.119-127
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    • 2011
  • The main purpose of this paper is to apply Zone 30 system which is being experimented in advanced country for the solution of controlling the residential street's speed to our country with the consideration of the real condition of our street and traffic and to run this system as an example to analyze the effect and at the same time, analyze the problem and get appropriate preparation for this system to be widespread. The area to run this model project is Goyang City Ilsan-Gu.($0.65km^2$) which is close with the commercial area reflecting the opinion of experts and an on-site verification by the National Police Agency T/F and is having a heavy pedestrian traffic and the risk of pedestrian accident. Firstly we defined residential street and residential street area to review the system and devided the residential street type to establish a plan of operation. Afterwards, we thoroughly examined the model project area and analyzed the problem and solution. We finally completed establishing a facilities by conference with a local autonomous entity with the improvement of facility's sketch at the analysis of the model project area. The result of effects analysis which we devided after and before of establishment is that vehicle speed be reduced 5~15km/h, and traffic accidents has decreased by 24 percent.

Study on the Adolescent Patient′s Stress during Hospitalization (청년기환자의 입원생활에 따르는 긴장에 관한 연구)

  • 백영주
    • Journal of Korean Academy of Nursing
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    • v.6 no.1
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    • pp.72-79
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    • 1976
  • Contemper nursing literature place much importance on human- centered and individualized care. Nursing research has related stress during hospitalization of adolescent patients to adaptation to a new environment, isolation from friends, limitation due to illness, over protection of parents and communication with member of the medical team. The investigator conducted this study in the hope that an understanding of adolescents responses to hospitalization, their perceptions, the kinds and levels of stress, and the relationships between stressors and individual characteristics would contribute to the improvement of adolescent patient care. The objective of the study was to obtain informations related to the adolescents psychological stress experience during hospitalization, specifically stress from interpersonal relationships and communication, isolation from the family, social or economic problems, illness and from the treatment environment and nursing care. An interview schedule adopted from Holmes and Rahe's Social Readjustment Rating Scale and selected items from Voicer's instrument on stress-producing events was used with 120 adolescent inpatients aged 13 to 18 years three general hospitals in Seoul during Aug. 10, to Sep. 30, 1975. 1. The sample consisted of 66 male and 54 female patients. Sixty-six percent were late adolescents, aged 16 to 18 years: 4% were early adolescents, aged 13 to 15 years. The primary cause for hospitalization was for orthopedic problems (35.8%). More than half of these (54.4%) were due to injury or accident. 2. Stress eclated to illness revealed the highest score (4.97), followed by stress related to treatment environment and nursing care (4.34) , isolation from family and social or economic problems (4.01) and interpersonal relationships and communication (3.96). 3. The perceived indifference of doctors and nurses was a serious cause of stress (mean=4.83). Fellow patients and visitors caused least stress (mean=2.06). 4. Discontinuation of education or unemployment were major stressful events (mean=4.71). Least stressful was isolation from the family (mean=3.47). 5. More than 94% of the respondents expressed fears related to body image (mean=4.97) 6. Within the category of treatment environment and nursing care, items related to restrictions because of treatment, discomfort because of treatment, inadequate explanation from nurses about procedures were rated as severe stress events (mean=4.6). Items related to the ward environment and to having a relative stay with them were seen by the group as less serious events (mean=3.7). 7. Stress related to interpersonal relationships and communication was correlated positively with female patients and those preferring passive activities. (P〈0.05) 8. Stress related to family problems was positively related to female and early adolescent patients (P< 0.05). Stress related to social problems was positively , elated to students and those preferring active pursuits (P< 0.05). 9. There were no correlation between the high stress related to disease and any of the characteristic items. (P> 0.05) 10. Stress related to treatment environment and nursing care was positively related of early adolescent and female and student patients. (P< 0.05) This group of hospitalized adolescents reported high level of stress related to treatment environment and nursing care, due to lack of consideration of normal growth and development and individual characteristics. The findings have important implications for the planning of effective, individualized, comprehensive nursing care of adolescents during hospitalization.

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Tolerability, Safety and Effectiveness of Paliperidone ER in Patients with Schizophrenia : A 24-Week Interim Analysis of the 48-Week Open-Label, Prospective, Switch Study (조현병 환자에서 Paliperidone Extended Release의 효능, 안전성 및 내약성 : 48주 개방형, 전향적 연구의 24주 중간 분석)

  • Choi, You Ra;Jung, Dong Chung;Kim, Eun Young;Kim, Se Hyun;Lee, Hyun Jeong;Lee, Nam Young;Chang, Sung Man;Shim, Joo Cheol;Joo, Eun Jeong;Kim, Jae Jin;Lee, Sang Hyuk;Chung, Young Chul;Kim, Yong Sik;Ahn, Yong Min
    • Korean Journal of Biological Psychiatry
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    • v.20 no.1
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    • pp.12-20
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    • 2013
  • Objectives We investigated the tolerability, safety, and treatment response to flexible-dose paliperidone ER in patients with non-acute schizophrenia in whom previous antipsychotic drugs were ineffective. Methods This 24-week interim analysis of the 48-week multicenter, prospective, open-label study assessed effectiveness using the Positive and Negative Syndrome Scale (PANSS), Clinical Global Impression-Schizophrenia-Severity (CGI-SCH-S) Scale, Personal and Social Performance (PSP) and Drug Attitude Inventory (DAI). Safety and tolerability were assessed using the Drug-Induced Extrapyramidal Symptoms Scale (DIEPSS) and Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS). Results Effectiveness was assessed in 169 patients. Significant improvement in the PANSS total score was observed by week-1 and continued until week-24. The response rate was 33%. The CGI-SCH-S and PSP total scores significantly improved during 24 weeks ; however, no change occurred in the total DAI. Fifty-nine percent of patients reported adverse events, of which extrapyramidal symptoms were the most frequent (19.0%). The DIEPSS and LUNSERS scores were improved after 24 week. Conclusions Switching to the flexible-dose paliperidone ER from an ineffective antipsychotic drug was safe, tolerable, and showed a good treatment response in Korean patients with schizophrenia.

Safety and Effectiveness of Long Acting Injectable Antipsychotic Paliperidone Palmitate Treatment in Schizophrenics : A 24-Week Open-Label Study (조현병 환자에서 장기지속형 항정신병 주사제 팔리페리돈 팔미테이트의 효능과 안전 : 24주 개방형 연구)

  • Kang, Hyun-Ku;Hahm, Woong;Shon, In-Ki;Paik, In-Ho
    • Korean Journal of Biological Psychiatry
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    • v.20 no.3
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    • pp.111-117
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    • 2013
  • Objectives We investigated the effectiveness and safety when treated in schizophrenics with paliperidone palmitate, a long acting injectable antipsychotic. Methods This was a 24-week open-label study, performed at one center in Korea. The eligible patients with schizophrenia diagnosed by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) criteria were enrolled. Patients received long-acting paliperidone palmitate injection (234 mg, baseline; 156 mg, week 1 ; then once 4 weeks flexible dosing). Effectiveness assessments were measured by the Positive and Negative Syndrome Scale (PANSS), The Clinical Global Impression Severity Scale (CGI-S), The Personal and Social Performance (PSP) at baseline, week 1, every 4 weeks untill 24 weeks or endpoint. Safety assessments were measured by The Extrapyramidal Symptom Rating Scale (ESRS), body weight (BW) and incidence of adverse events. Oral antipsychotics were stopped or tapered off within next 14 days. Results Of 20 patients recruited, 9 patients (45%) completed the study. Paliperidone palmitate produced a significant improvement in PANSS total score from baseline to endpoint. The response rate was 75% [mean change (${\pm}SD$) $-25.9{\pm}14.4$, all p < 0.001]. The CGI-S and PSP total scores significantly improved during 24 weeks (All p < 0.001). Eighty percent of patients reported adverse events and most common adverse events (${\geq}10%$) in paliperidone palmitate were anticholinergic adverse event, extrapyramidal symptoms, weight gain, akathisia, insomnia, headache, agitation, anxiety and GI trouble. ESRS score is not statistically significant, but tends to get better at the end of the study when compared to baseline. Conclusions Our study results demonstrated maintained effectiveness and safety of paliperidone palmitate treatment in schizophrenics. And provides both clinicians and patients with a new choice of treatment that can improve the outcome of long term therapy. Their potential effectiveness and safety should be better addressed by future randomized-controlled trials.