• Title/Summary/Keyword: Penis

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Healthcare Research for Premature Ejaculation and Erectile Function Using Questionnaire of Smartphone SNS (스마트 폰 SNS의 설문을 통한 조루증 및 발기능에 관한 헬스케어 연구)

  • Yoon, Jung-Dae;Heo, Sung-Jin;Na, Chang-Ho;Kim, Sung-Hyun;Moon, Jong-Hoon
    • The Journal of the Korea institute of electronic communication sciences
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    • v.12 no.6
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    • pp.1197-1210
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    • 2017
  • This study aimed to compare premature ejaculation and erectile function according to penile characteristics. 99 adult men responded to a questionnaire on penile characteristics, premature ejaculation and erectile function. In the questionnaire survey, 69 questionnaires were analyzed except missing or incomplete answers. All collected data were analyzed by independent t test, Chi-square test using SPSS 22. Glans > penis type showed significant differences in subjective premature ejaculation and objective premature ejaculation compared to Glans ${\frac{._-}{.}$ penis type (p <.05). Men with subjective premature ejaculation showed significant differences in objective premature ejaculation, treatment intent, and satisfaction compared to men without subjective premature ejaculation (p <.05). Presence of objective premature ejaculation, presence of treatment intent, and marital status were significantly different in satisfaction (p <.05). In economic status, high was significantly different in confidence for erectile function compared to middle or low (p <.05). The results of this study suggest that the premature ejaculation and erectile function according to the penile characteristic may be different and may be used as a basis for the development of an intervention program for sexual rehabilitation of men with premature ejaculation and erectile dysfunction.

Nitric oxide(NO) mediating non-adrenergic non-cholinergic(NANC) relaxation in the boar retractor penis muscle II. Comparison of the relaxant properties induced by nonadrenergic, noncholinergic nerve stimulation and S-nitrosothiols in the porcine retractor penis muscle (Nitric oxide에 의한 수퇘지 음경후인근의 비아드레날린 비콜린 동작성 이완 II. 비아드레날린 비콜린성 신경의 전장자극과 S-nitrosothiols에 의한 돼지 음경후인근의 이완 효과 비교)

  • Mun, Kyu-whan;Kim, Tae-wan;Kang, Tong-mook;Lee, Wan;Yang, Il-suk
    • Korean Journal of Veterinary Research
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    • v.35 no.3
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    • pp.459-469
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    • 1995
  • As S-nitrosothiols were proposed as nitrergic carriers in vascular and nonvascular smooth muscle, we have investigated the relaxant properties of several S-nitrosothiols in the porcine retractor penis(PRP) muscle and compared them with the effects of exogenously added NO, electrical field stimulation(EFS) of NANC nerves and sodium nitroprusside(SNP). Also the influences of oxyhemoglobin and hydroquinone on the relaxant responses were investigated. In addition, effects of NO on membrane potentials and its involvement in the generation of inhibitory junction potential(IJP) were investigated with conventional intracellular microelectrode technique. The results were summerized as follows. 1. Frequency-dependent relaxations of PRP muscle were induced by EFS to NANC nerve. Tetrodotoxin($1{\times}10^{-6}M$) abolished the relaxations of PRP muscle induced by EFS, and L-NAME(($2{\times}10^{-5}M$) and methylene blue($4{\times}10^{-5}M$) inhibited the relaxations. L-NAME-induced inhibition of the relaxations was reversed by L-arginine($1{\times}10^{-3}M$), but not by D-arginine. 2. Exogenous NO($1{\times}10^{-5}-1{\times}10^{-4}M$), sodium nitroprusside(($1{\times}10^{-7}-1{\times}10^{-4}M$) induced dose-dependent relaxations of PRP muscle. All S-nitrosothiols($1{\times}10^{-7}-1{\times}10^{-4}M$) tested relaxed the PRP muscle in dose-dependent manner and the potency order was SNAP>GSNO>CysNO>SNAC. 3. Oxyhemoglobin($5{\times}10^{-5}M$) blocked the relaxation induced by exogenous NO and inhibited EFS-, S-nitrosothiols-, and SNP-induced relaxation. 4. Hydroquinone($1{\times}10^{-4}M$) also abolished the relaxations induced by exogenous NO, and reduced the relaxations induced by S-nitrosothiols, but did not affect EFS- and SNP-induced relaxations. 5. SNP($2{\times}10^{-6}-5{\times}10^{-6}M$) relaxed muscle strips but the membrane potentials were not affected. 6. EFS with several pulses(1ms, 2Hz, 80V) produced an inhibitory junction potential(IJP) with muscle relaxation. They were abolished by TTX($2{\times}10^{-6}M$). $N^G$-nitro-$_{\small{L}}$-arginine(L-NNA, $2{\times}10^{-5}M$) abolished the muscle relaxation, but had no effect on IJP.

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Distribution and Effect on Organisms of Butyltin Compounds Inside Songsan Harbor of Cheju Island (제주도 성산항내 부틸주석화합물의 분포와 생물체에 미치는 영향)

  • 김상규;안이선;고병철;조은일;이기호
    • Journal of Environmental Science International
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    • v.9 no.4
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    • pp.285-294
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    • 2000
  • Butyltin compounds (BTs) in seawater, sediments and organisms (Thais clavigera, Liolophura japonica and Cellana nigrolineata), were quantitatively determined to evaluate their distribution inside Songsan Harbor of Cheju Island. In addition, imposex in T. clavigera was used to assess the effect on organisms of BTs. Analysis of the samples collected in seawater, sediments (March, June and August) and organisms (May, July and August) in 1998, confirmed the contamination of BTs in the aquatic environment inside Songsan Harbor. The main BTs species in seawater and sediments was monobutyltin (MBT), tributyltin (TBT), respectively, irrespective of survey time. In oranisms, TBT and dibutyltin (DBT) were detected in similar concentrations for T. clavigera and L. japonica, but for C nigrolineata, DBt concentration was the highest. TBT, the most toxic to aquatic organisms among BTs, was found at concentrations which were sufficient to have a serious effect on the sensitive organisms upon chronic exposure, The relatively high correlations (r>0.83) between BTs indicated that DBT and MBT were mainly degraded from TBT based on antifouling paint and their sources were negligible. The sedimentary organic matters did not have influence on the distribution of BTs in marine environment, and lipid content in T. clavigera did not show a correlation with TBT concentrations. The rate of occurrence of imposex in T. clavigera was 100%, and the relative penis length index (RPLI) and the relative penis size index (RPSI) which represent the degree of imposex were 79.7%, 58.1%, respectively. Measurement of imposex in T. clavigera was expected to be a very helpful tool for preliminary survey of BTs prior to trace analysis of BTs.

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A Case Report of treating Stuttering Priapism (재발성 음경지속발기증 1례)

  • Park, Sung-Hwan;Paik, Sun-Ho;Han, Su-Ryun;Ahn, Young-Min;Ahn, Se-Young;Lee, Byung-Cheol
    • The Journal of Internal Korean Medicine
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    • v.32 no.1
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    • pp.136-143
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    • 2011
  • Priapism is a persistent penile erection that continues for more than 4 hours beyond, or is unrelated to, sexual stimulation. Because priapism is a medical emergency, all patients with priapism should be evaluated and treated urgently. Subtypes of priapism are ischemic, non-ischemic and stuttering priapism. Stuttering type is a recurrent form of ischemic priapism in which unwanted painful erections occur repeatedly with intervening periods of detumescence. The etiology of this type is often idiopathic and the treatments are still not clearly established. We present one case of stuttering priapism which occurred after suppression of his sexual desire. A 23-year-old man visited our clinic complaining of recurrent pain and erections persisting for about 5 weeks. We performed evaluation and confirmed the diagnosis of Rigid swollen penis. Jibaekjihwang-tang gamibang (ZhiBaiDihuang-Tang Jiaweifang) was administerd to the patient for 9 days. After the treatment, duration of erections and pain showed remarkable improvements. This will be recorded as the first case report of treating priapism with a Korean medical approach and suggests that Korean medicine therapy can be efficient to treat priapism.

Report on the Annual Reproductive Cycle and Imposex Phenomenon of the Rock-Shell, Thais clavigera in Jeju Port (제주항 내에 서식하는 신복족류 Thais clavigera의 연중 생식주기 및 임포섹스 현상에 관한연구)

  • Yang, Hyun-Sung;Kim, Bong-Kyu;Park, Heung-Sik;Choi, Kwang-Sik
    • The Korean Journal of Malacology
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    • v.26 no.1
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    • pp.97-105
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    • 2010
  • Annual gonad development of the rock shell, Thais clavigera distributed in Jeju Port was investigated over a 12 month period from March 1998 to February 1999. Monthly change in gonad development was examined using histology. Gametogenesis of T. clavigera in the study area initiated as early as in October and fully ripe eggs could be observed from May to July. Percent gonad area (PGA) also increased rapidly from May to July then dropped in August when the water temperature remained $22.6-24.5^{\circ}C$, suggesting that rock shell released their eggs during this period. All female rock shell collected during the course of study exhibited pseudo-penis in the head, indicating that a certain level of imposex had progressed in the study site. Relative penis size index (RPSI), an indicator of level of imposex phenomenon varied 59.5-173.4% and this value was relatively higher than the index reported from elsewhere. It was believed that such imposex phenomenon observed in T. clavigera was caused by endocrine disruption by chemical contaminants such as TBTs released from biocidal paints in the port environment.

Aesthetic Images in Men s Bodies and Fashion(I) - Focused on Eroticism in Men s Fashion- (남성의 몸과 패션에 표현된 미적 이미지(I) -남성 패션에 표현된 에로티시즘을 중심으로-)

  • 이민선;김민자
    • Journal of the Korean Society of Costume
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    • v.51 no.1
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    • pp.163-174
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    • 2001
  • The purpose of this study is to review the features of eroticism expressed in men's fashion, to explain psychological and social contexts which engender eroticism and to analyze in what way eroticism is portrayed in men s fashion in this context. Eroticism as the metonymy of forbidden sexual desire, has been embodied mostly in visual forms such as picture and photo. From a psychoanalytic view, the context in which eroticism is formed can be explained by primary narcissism and fetishism. Primary narcissism is the feeling of satisfaction with the self in which the subject who is admiring and the object of admiration are one and the same. Accordingly, in order to give rise to eroticism, both subject and object have to exist. Fetishism, the metonymy of castrated penis, is also one of the factors to produce eroticism. Metaphorically seen as a woman who has a penis, a man who dresses in the same manner as a woman dresses can be a source of eroticism to gays. From a sociological view, the context in which eroticism is fostered depends on the dynamic relations among social powers. In these relations, who is a subject or who is an object has been continuously changing. In the Post-modern culture appearing in the late 20th century, power begins to take various forms, and gays and women who had never been subjects begin to make man an object of eroticism. The other point is that social morality, ignoring desire itself, objectifies sexual desire and seeks to remove It by exchanging it for objectified symbols. The design elements provoking eroticism in men s fashion are exposure and decoration. In particular, models in exposure and decorative fashion have been objectified through the methods of fragmentation rather than showing the whole figure or removing a person s individuality or will,.

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Penile Translocation Surgery in Lateral Recumbency of a Calf Using Tilt-Up Mobile (대동물 보정 차량을 이용한 횡와위 자세 육성우의 음경전위술)

  • Jeong, Jae-Kwan;Moon, Sung-Ho;Kang, Hyun-Gu;Kim, Ill-Hwa
    • Journal of Veterinary Clinics
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    • v.29 no.1
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    • pp.112-117
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    • 2012
  • This report evaluated the convenience and accessibility of a penile translocation surgery in the lateral recumbency of a calf using a tilt-up mobile compared with that of dorsal recumbency on the ground of a barn. One nine-month-old F-1 (Korean native sire x Holstein dam) calf was sedated with xylazine (0.03 mg/kg, IV) and restrained in the right lateral recumbency position on a tilt-up restraint mobile (90 cm high), whereas the other nine-month-old Korean native calf was administered xylazine (0.3 mg/kg, IV) and restrained in dorsal recumbency position on the ground of a barn, with assistance by one person. For the two calves, lidocaine was administered subcutaneously from the preputial orifice to the S-shaped penis. The preputial orifice was incised, and the preputial sheath and penis were separated bluntly, then laterally translocated to the site toward the left flank at a $40^{\circ}$ angle. Anti-inflammatory drug (ketoprofen) and antibiotics (penicillin) were administered following the surgery. The duration of surgery was 30 min shorter in the calf that received the surgery in lateral recumbency using the tilt-up mobile with operator's standing posture (60 min) than the one that underwent surgery in dorsal recumbency on the ground with operator's bending posture (90 min). One week after the surgery, the operation area, including the translocated preputial orifice, was healed without complications in both cases. The results detailed in this report demonstrate that penile translocation surgery in the lateral recumbency position using a tilt-up mobile might be used conveniently in calves due to the convenience of restraint, reduced surgery time, and reduced physical inconvenience for the surgeon.

Nitric oxide(NO)-mediated relaxation of bovine retractor penis muscle (소 음경후인근의 Nitric oxide(NO) 매개성 이완)

  • Yang, Il-suk;Chang, Hee-jung;Kang, Tong-mook;Lee, Jang-hern
    • Korean Journal of Veterinary Research
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    • v.36 no.3
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    • pp.599-605
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    • 1996
  • This study was designed to examine the mechanism of penile erection in adult bull by analyzing the responses of bovine proximal retractor penile muscle strips(BRP) to electtical field stimulation(EFS), exogenous nitric oxide(NO), NO synthesis precursor(L-arginine), NO synthase inhibitors(L-NAME, L-NMMA), guanylate cyclase inhibitor(methylene blue) and nonspecific potassium channel blocker(tetraethylammonium, TEA) treatments. Isometric tension of BRP was measured using physiograph. Results were summarized as follows: 1. EFS of nonadrenergic noncholinrgic(NANC) nerve in BRP produced frequency-dependent inhibitory responses to the contraction induced by co-treatment of epinephrine, guanethidine and atropine. The inhibitory responses to EFS were blocked by tetrodotoxin(TTX, $1{\mu}M$). 2. Treatment of L-NAME ($10,\;20{\mu}M$) inhibited the relaxation to EFS whereas L-NMMA ($100{\mu}M$) had no effect. 3. Treatment of NO($20,\;40{\mu}M$; as an acidified solution of $NaNO_2$) induced concentration-dependent relaxation whereas preincubation of TTX($1{\mu}M$) and L-NAME($20{\mu}M$) had no effect on the relaxation response. 4. L-arginine treatment(10mM) blocked the inhibitory effect of L-NAME($20{\mu}M$). 5. Pretreatment of methylene blue($40{\mu}M$) reduced the NANC-induced relaxation of BRP. 6. Tetraethylammonium(TEA, 80mM) reduced NANC relaxation. These results suggest that NO may act as a NANC neurotransmitter in BRP and the effects might be mediated by cGMP and potassium channel.

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Hershberger Assays for Di-2-ethylhexyl Phthalate and Its Substitute Candidates

  • Kim, Hee-Su;Cheon, Yong-Pil;Lee, Sung-Ho
    • Development and Reproduction
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    • v.22 no.1
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    • pp.19-27
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    • 2018
  • In the present study, we employed Hershberger assay to determine possible androgenic or antiandrogenic activities of three di-2-ethylhexyl phthalate (DEHP) substitute candidates. The assay was carried out using immature castrated Sprague-Dawley male rats. After 7 days of the surgery, testosterone propionate (TP, 0.4 mg/kg/day) and test materials (low dose, 40 mg/kg/day; high dose, 400 mg/kg/day) were administered for 10 consecutive days by subcutaneous (s.c.) injection and oral gavage, respectively. Test materials were DEHP, 2-ethylhexyl oleate (IOO), 2-ethylhexyl stearate (IOS) and triethyl 2-acetylcitrate (ATEC). The rats were necropsied, and then the weights of five androgen-dependent tissues [ventral prostate, seminal vesicle, coagulating glands, levator ani-bulbocavernosus (LABC) muscle, paired Cowper's glands, and glans penis] and four androgen-insensitive tissues (kidney, adrenal glands, spleen and liver) were measured. All test materials including DEHP did not exhibit any androgenic activity in the assay. On the contrary, antiandrogen-like activities were found in all test groups, and the order of the intensity was ATEC < DEHP < ISO < IOO in the five androgen-sensitive tissues. There was no statistical difference between low dose treatment and high dose treatment of all replacement candidate groups. In DEHP groups, high dose treatment exhibited significant weight gains in LABC and Glan Penis. There was no statistical difference in androgen-insensitive tissue measurements. Since the effects of ATEC treatment on the accessory sex organs were much less or not present at all when compared to those of DEHP, ATEC could be a strong candidate to replace DEHP. IOO treatment brought most severe weight reduction in all of androgen-sensitive tissues, so this material should be excluded for further screening of DEHP substitute selection.

A Morphological Study on the Male Genital Organs of a Land Snail, Nesiohelix samarangae (동양달팽이의 웅성 생식기관에 대한 형태학적 연구)

  • 이훈섭;정계헌;박종안
    • The Korean Journal of Malacology
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    • v.8 no.1
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    • pp.61-71
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    • 1992
  • 동양달팽이 (Nesiohelix samarangae)는 동양달팽이속(Nesiohelix)에 속하는 종으로 한국에서 동양?팽이속으로는 유일하게 발견되는 종이다. 본 실험에서는 동양달팽이의 웅성생식기관의 각 부분 즉, 난정소(ovotestis), 양성관(hermaphrodite duct), 수정실(fertilization chamber), 전립선(prostate), 수정관(vas deferens), 상음경(epiphallus), 음경(penis)등의 배열 상태를 관찰하고 이들에 대한 광학현미경적 관찰을 위해 Hematoxylin- Eosin염색과 Mallory 염색을 실시하였다. 난정소(ovotestis)는 많은 수의 선포(acini)로 이루어져 있으며 각 선포는 배상피세포층(germinal epithelial cell layer)과 영양세포(nurse cell), 생식세포(gamete cell)들로 이루어져 있었다. 선포(acini)는 원주상피로 덮여있었다. 양성관(hermaphrodite duct)은 가늘고 긴 관으로 내벽은 섬모입방상피세포와 얇은 결합조직층으로 이루어져 있었으며 내강은 농축된 정자로 가득 차 있었다 . 수정관(fertilization chamber)은 3개의 도관이 결합조직에 의해 둘러싸인 형태로 이루어져 있었다. 도관의 상피세포는 뚜렷한 위중층섬모원주세포로 되어 있었다. 전립선(prostaoe)은 분비기능을 가진 것으로 사료되는 세포들과 실제 분비가 일어나는 실(chamber)로 이루어져 있었으나 다른 염색법 또는 전자현미경적 관찰에 의해 다른 구조들의 존재유무를 확인 해야할 것으로 사료된다. 실(chamber)은 분비포로 보이는 세포들과 접해 있었다. 수정관(vas deferens)은 결합조직으로 이루어진 근육질의 두꺼운 벽을 가지고 있었으며 내강은 돌출부위에 의해 4부분으로 갈라져 있었다. 내강에 연한 상피는 원주세포로 되어 있었다. 상음경(epiphallus)의 벽은 근섬유 다발은 벽의 외곽으로 갈수록 밀도가 높아졌다. 상부에 내강과 연결되는 함입구조(groove)를 가지며, 내강에 연한 상피는 섬모가 없는 원주세포로 이루어져 있었다. 음경(penis)은 근섬유가 산재된 두꺼운 벽을 가졌으며 상음경보다 굵은 원통형이었다. 내강은 많은 돌출부에 의해 복잡하게 나뉘어 있으며 상피세포는 원주 세포로 이루어져 있었고 섬모는 관찰되지 않았다. 내강 내의 분비물과 세포의 형태로 보아 내강상피세포는 분비기능을 가진 것으로 사료된다.

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