• Journal of Dental Anesthesia and Pain Medicine
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• 제20권3호
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• pp.107-118
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• 2020

Chloral hydrate is the oldest and most common sedative drug used in moderate sedation for pediatric dental patients. Hence, the purpose of this article is to review the safety and possible adverse events of this drug when used for pediatric dental treatment. A bibliographic search in PubMed, MEDLINE, Cochrane Library and KMbase, KISS, DBpia, KoreaMed, and RISS databases was performed. Using the keywords "dental sedation," "chloral hydrate," and "children or adolescent," 512 scientific articles were found. Subsequently, 183 studies were individually assessed for their suitability for inclusion in this literature review. Altogether, 24 studies were selected. They included 12 cases of death before, during, or after chloral hydrate sedation for dental treatment, majorly due to dosing error and use of multiple sedatives. Additionally, intraoperative adverse events were mostly respiratory problems such as hypoxia and apnea, but most events were temporary. After treatment, prolonged sedation, including excessive sleep and less activity were the most common postoperative adverse events, and even death cases were reported. Despite the wide acceptance of chloral hydrate as a sedative-hypnotic agent, the risk of adverse events and adequate dose should be of great concern when using it for pediatric dental sedation.

• 대한소아치과학회지
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• 제41권1호
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• pp.18-26
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• 2014

심한 불안이나 불수의적인 움직임으로 행동조절이 어려운 소아와 장애인의 치과치료를 위해 깊은 진정법이 고려된다. 응급 치과진료에 있어 세보플루란 흡입을 이용한 깊은 진정이 빠른 유도와 회복으로 인해 선호된다. 2013년 1월부터 2013년 10월까지 세보플루란을 이용한 깊은 진정을 받은 소아와 장애인 121명을 대상으로 조사분석하였다. 깊은 진정법을 사전 계획한 환자군과 소아외상이나 장애인의 특성 등으로 응급으로 시행한 환자군을 비응급 세보플루란진정군과 응급 세보플루란진정군으로 나누었다. 비응급 세보플루란진정을 받은 환자는 95명이었고 응급 세보플루란진정을 받은 환자는 26명이다. 두 군간에 성별, 나이, 진정법을 시행한 이유, 유도방법, 진정시간 및 치료시간, 치료내용, 진료과를 비교분석하였다. 비응급 세보플루란진정은 소아와 장애인의 행동조절에 안전하고 효과적으로 사용되었고 응급 세보플루란진정은 외상을 입은 어린 소아환자의 짧고 간단한 치료에 유용하게 사용되었다. 세보플루란을 이용한 깊은 진정은 점차적으로 전신마취의 사용을 줄이고 소아와 장애인 환자의 응급 치과진료에 유용한 방법이었다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제15권2호
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• pp.47-52
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• 2015

Sedation allows patients to maintain their airway independently and respond appropriately to physical stimulation and verbal command while maintaining a minimum depressed level of consciousness. Drugs commonly used for sedation of pediatric dental patients include a combination of chloral hydrate, hydroxyzine, and nitrous oxide-oxygen. Midazolam is a benzodiazepine and currently one of the most commonly used intravenous sedative agents. It can be easily titrated to provide a wide range of sedation, from conscious sedation to deep sedation, and exhibits a wide safety margin without severe respiratory and circulatory depression. At an appropriate dose, it also decreases patient anxiety and induces amnesia. We found that the submucosal administration of midazolam combined with chloral hydrate provided increased sedative effects and decreased the postoperative vomiting response compared with conventional chloral hydrate administration, with no significant difference in physiological responses. The depth of sedation can be titrated using this technique.

• 대한소아치과학회지
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• 제43권1호
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• pp.85-92
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• 2016

대한소아치과학회는 진정법 교육연구위원회를 설립하여 학회원들이 진정법을 시행함에 있어서 안전한 술식을 시행할 수 있도록 진정법 지침서를 개정하고 평생교육프로그램을 개발하게 하였다. 이에 2015년 종합학술대회 기간에 진정법 심포지움과 BLS교육을 시행하였으며, 이에 대한 학회원들의 만족도 평가를 시행하였다. 진정법연구교육위원회는 종합학술대회에 참가한 학회원들에게 배포할 설문지를 제작하여 심포지움에 참가한 학회원 중 설문에 응한 총 143명의 학회원들의 설문지를 분석하였으며, BLS코스에 참여한 23명의 학회원을 대상으로 설문지를 배포하여 이를 분석하였다. 심포지움과 BLS코스에 참석한 학회원들은 전반적인 질문에 대하여 높은 만족도를 보였으며, 진정법 교육연구위원회는 이번 설문지를 통하여 학회원들이 원하는 교육내용과 향후 교육프로그램 개발에 관한 중요한 정보를 얻을 수 있었다. 대한소아치과학회는 앞으로도 꾸준히 학회원들의 더 낳은 교육을 위하여 힘 쓸 것이며, 체계적인 교육프로그램 개발을 위하여 노력할 것이다.

• 한국치위생학회지
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• 제9권2호
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• pp.137-146
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• 2009

In pediatric dentistry, sedation therapy is one of methods for managing children's behavior, and various types of sedation therapy are being used. Thus, this study surveyed the awareness of and satisfaction with sedation therapy in 204 parents who visited the Pediatric Dentistry using a self-administered questionnaire during the period from June to December 2008 in order to get information necessary in behavior management for pediatric patients, and obtained results as follows. 1. The most common path of learning about sedation therapy was dentistry (49.5%), and the most common reason for choosing sedation therapy was 'The child was young'(42.3%), which was followed by 'The child is too afraid'(18.8%), 'There are many teeth to be treated'(16.0%), 'To adjust the number of visits'(11.3%), and 'For behavior management'(3.1%). 2. Most of the parents felt anxiety about sedation therapy, and the reasons for the anxiety were 'The child was young'(33.0%), 'Worry about side effects'(31.3%), 'Worry about recovery of consciousness'(25.7%), 'Worry about the blunting of intellectual abilities'(7.6%), and others (2.4%). 3. Satisfaction with sedation therapy was higher in men than in women, and was high in order of 'Stationing of an anesthetist', 'One time completion of treatment', and 'Cautions'. Statistically significant difference was observed between men and women only in question "Have you ever heard about sedation therapy?"(p=0.018). 4. According to age, satisfaction with sedation therapy was highest in parents whose child was less than 48 months old. Satisfaction was high in order of 'Stationing of an anesthetist', 'One time completion of treatment', and 'Cautions', 'Choice of sedation therapy', and statistically significant difference was observed according to age only in question "Have you ever heard about sedation therapy?"(P=0.005). 5. Positive correlation was observed among questions on satisfaction with sedation therapy. In the survey on the awareness of and satisfaction with sedation therapy in parents visiting the dentistry, awareness and satisfaction were generally high with regard to the parents' choice of sedation therapy, but many of the parents answered that they chose sedation therapy and felt anxiety because their child was young. The results of this study need to be considered for behavior management in pediatric dentistry and there should be systematic education and promotion of sedation therapy.

• 대한소아치과학회지
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• 제26권4호
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• pp.579-588
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• 1999

치과에서 행해지는 진정요법이 안전하게 수행되기 위해서는 환자에 대한 모니터가 필수적이다. 우리나라에서 소아치과의사에 의해 이루어지는 진정요법에 관해 알아보고자 대한소아치과학회 회원 245명을 대상으로 1998년 10월 1일부터 1998년 12월 20일까지 진정요법의 사용여부 및 사용하는 진정요법의 빈도, 방법, 사용하는 약물, 용량 결정, 모니터 여부, 응급장비 등에 관한 설문조사를 실시하여 다음과 같은 결론을 얻었다. 1. 설문지 응답자의 29%에서 진정요법을 이용하여 치료를 하는 것으로 조사되었다. 설문지 응답자의 71%에서는 진정요법을 하지 않는 것으로 조사되었다. 2. 진정요법을 사용하는 사람 중 61%에서만 진정요법 치료시 모니터를 사용하는 것으로 조사되었다. 진정요법을 사용하는 사람의 39%에서는 진정요법 치료시 모니터를 사용하지 않는 것으로 조사되었다. 3. 가장 흔하게 사용되는 진정요법은 아산화질소-산소를 이용한 흡입진정요법이었다. 그 외에 경구 투여시 가장 흔하게 사용되는 약물은 chloral hydrate였다. 4. 진정요법을 사용하는 사람의 28%에서만 동의서를 작성하는 것으로 조사되었다. 5. 진정요법을 이용하여 치료를 한다고 응답한 사람의 60%에서만 응급장비를 구비하고 있으며, 응답자의 91%에서 응급처치에 관한 교육이 필요하다고 응답하였다.

• 대한소아치과학회지
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• 제33권1호
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• pp.62-69
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• 2006

본 연구의 목적은 소아의 비만도가 진정요법의 효과에 미치는 영향을 알아보는 것이다 삼성서울병원 소아치과에 내원한 환자 중 ASA I 또는 II에 해당하는 40명의 환아 (평균연령 30.5개월, 평균신장 91.3cm, 평균체중 14.3kg)를 대상으로 chloral hydrate(60mg/kg) 및 hydroxyzine(25mg)을 사용하여 진정요법을 시행하였다. 환아의 체중과 신장을 이용하여 환아 각각의 비만도를 계산하였고 Broadsky's scale을 이용하여 편도선의 크기를 측정하였다. 진정요법에 대한 결과는 Houpt's scale(수면, 움직임, 울음, 전반적인 행동지수)을 이용하여 평가하였다. 환아의 비만도는 진정효과중 움직임과 울음에 대하여는 통계학적으로 유의한 차이를 만들지 않았으나 비만도가 증가할수록 전반적인 행동지수가 유의하게 나빠지는 결과를 보였다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제16권4호
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• pp.283-288
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• 2016

Background: Sevoflurane sedation in pediatric and disabled patients has the advantage of faster induction and recovery compared to general anesthesia, as well as minimum influence on the respiratory and cardiovascular functions, and airway protective reflexes. This study aimed to evaluate the clinical efficacy of sevoflurane sedation used in dental treatment at one provincial dental clinic center for the disabled. Methods: We investigated patients' gender, age, reasons for undergoing sedation, medication history prior to treatment, duration of anesthesia, treatment length, type of treatment, and yearly patterns, for 387 cases of dental treatment performed using sevoflurane sedation from January 2013 to October 2016. Results: We analyzed 387 cases (215 male patients, 172 female patients). Male patients aged 20 year or older accounted for 39.0% of all patients, marking the highest proportion. Patient's lack of cooperation was the most common reason for performing dental sedation. Prosthetic treatment was the most frequently practiced, accounting for 174 treatment cases. The mean lengths of the entire treatment and of the dental procedure were 55.2 min and 39.8 min, respectively. Conclusions: Sevoflurane sedation has the advantage of fast anesthesia induction and recovery compared to general anesthesia; therefore, it can be used efficiently to induce anesthesia in pediatric and disabled patients during short dental procedures, enabling stable treatment of these patients.

• 대한치과마취과학회지
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• 제13권3호
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• pp.95-102
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• 2013

Background: Sedation or outpatient general anesthesia is a necessary method for a successful dental treatment for children and the disabled who have a difficulty of cooperation. The aim of this study was to assess the patients who had dental treatment under sedation or outpatient general anesthesia at department of pediatric dentistry, Chonnam national university dental hospital and Gwangju dental clinic for the disabled. Methods: 875 patients who had sedation from January 2009 to September 2013 and 88 patients who had outpatient general anesthesia after May 2011 were assessed for this study. Patient's distribution and treatment patterns were examined. Results: The number of patients has been increasing in both sedation and outpatient general anesthesia. In case of sedation, the proportion of male patients was higher and 4-6 years age group was the highest. Most patients have resided in Gwangju buk-gu and the percentage of restorative treatment was the highest. In case of outpatient general anesthesia, the proportion of male patients was higher than that of sedation. Two groups, 10-19 and 20-29 years age, consisted most of patient. Most patients have resided in Gwangju buk-gu and Jeollanam-do, and the percentage of periodontic and preventive treatment was the highest. Conclusions: Sedation or outpatient general anesthesia for dental treatment has been increasing for children and the disabled who have a difficulty of cooperation. Therefore, it is important to improve treatment environment under sedation and general anesthesia through continuous research and studies.

• Journal of Dental Anesthesia and Pain Medicine
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• 제15권1호
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• pp.11-15
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• 2015

Background: Emergency room doctors run into difficulties in treating injured pediatric patients because usually they fell into panic after trauma. In these situation, deep sedation with sevoflurane is fully recommendable method. The conventional way can interrupt common dental treatment procedure. Methods: In the present study, nasal cannula was used for sevoflurane deep sedation in 11 dental emergency treatment. Age ranged from 0 to 3 years old (average of 1.8 years). Results: Treatment duration was from 10 to 35 minutes (average of 16.7 minutes). Average duration of sedation was 25.5 minutes ranging from 15 to 45 minutes. Conclusions: It has advantages to use nasal cannula for sevoflurane deep sedation rather than conventional intubation; saves time and secures good operation field.