• Journal of Korean Neurosurgical Society
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• 제61권3호
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• pp.363-375
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• 2018

Intraoperative monitoring (IOM) utilizes electrophysiological techniques as a surrogate test and evaluation of nervous function while a patient is under general anesthesia. They are increasingly used for procedures, both surgical and endovascular, to avoid injury during an operation, examine neurological tissue to guide the surgery, or to test electrophysiological function to allow for more complete resection or corrections. The application of IOM during pediatric brain tumor resections encompasses a unique set of technical issues. First, obtaining stable and reliable responses in children of different ages requires detailed understanding of normal age-adjusted brain-spine development. Neurophysiology, anatomy, and anthropometry of children are different from those of adults. Second, monitoring of the brain may include risk to eloquent functions and cranial nerve functions that are difficult with the usual neurophysiological techniques. Third, interpretation of signal change requires unique sets of normative values specific for children of that age. Fourth, tumor resection involves multiple considerations including defining tumor type, size, location, pathophysiology that might require maximal removal of lesion or minimal intervention. IOM techniques can be divided into monitoring and mapping. Mapping involves identification of specific neural structures to avoid or minimize injury. Monitoring is continuous acquisition of neural signals to determine the integrity of the full longitudinal path of the neural system of interest. Motor evoked potentials and somatosensory evoked potentials are representative methodologies for monitoring. Free-running electromyography is also used to monitor irritation or damage to the motor nerves in the lower motor neuron level : cranial nerves, roots, and peripheral nerves. For the surgery of infratentorial tumors, in addition to free-running electromyography of the bulbar muscles, brainstem auditory evoked potentials or corticobulbar motor evoked potentials could be combined to prevent injury of the cranial nerves or nucleus. IOM for cerebral tumors can adopt direct cortical stimulation or direct subcortical stimulation to map the corticospinal pathways in the vicinity of lesion. IOM is a diagnostic as well as interventional tool for neurosurgery. To prove clinical evidence of it is not simple. Randomized controlled prospective studies may not be possible due to ethical reasons. However, prospective longitudinal studies confirming prognostic value of IOM are available. Furthermore, oncological outcome has also been shown to be superior in some brain tumors, with IOM. New methodologies of IOM are being developed and clinically applied. This review establishes a composite view of techniques used today, noting differences between adult and pediatric monitoring.

• 재활치료과학
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• 제2권1호
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• pp.13-23
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• 2013

강제유도운동치료는 최근 신경재활 분야에서 가장 주목 받고 있는 상지 재활 치료방법 중 하나로 하루 6시간씩 주 5일 2주간 강도 높은 훈련을 환측 팔에 제공하고, 건측의 사용을 억제하기 위해 깨어 있는 시간의 90%를 구속하는 치료방법이다. 최근에는 전통적인 강제유도운동치료의 임상적 한계를 바탕으로 수정된 강제유도운동치료가 많이 적용되고 있다. 수정된 강제유도운동치료는 하루 5시간씩 주 5일, 10주간 건측을 억제하고 하루 30분간 손상측을 치료하는 방법이다. 이는 일상생활 수행 평가인 소아 운동 활동 측정표(Pediatric Motor Activity Log; PMAL)와 상지 질적 평가(Quality of Upper Extremities Skills Test; QUEST), 환측의 상지 기능을 평가하는 멜버른 상지 평가(Melbourne Assessment of Unilateral Upper Limb Function; MAULF), 환측과 건측의 양손 협응을 보기 위한 Assisting Hand Assessment(AHA)를 통해 강제유도운동치료의 효과를 입증하였다. 본 고찰에서는 강제유도운동치료 적용 후, 신경학적 변화를 살펴본 연구를 중점적으로 분석하였다. 경직성 편마비형 뇌성마비 아동에게 강제유도운동치료 또는 수정된 강제유도운동치료를 적용한 결과, 신체부분의 움직임의 양에 따라 대뇌피질에 나타나는 신체 부위의 크기가 변한다는 것을 보여주었다. 또한 반대측 운동피질의 활성을 증가시켜주고, 동측 피질의 활성을 감소시켜 신경재조직에 영향을 주기 때문에 강제유도운동치료는 신경가소성의 원리를 이용한 상지 재활 치료 방법이라 하겠다.

• 대한장애인치과학회지
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• 제10권1호
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• pp.43-46
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• 2014

뇌성마비로 인하여 협조를 얻기가 어려운 일부 혼합치열기 환자의 심미적, 기능적 개선을 위한 구내 고정성 장치의 사용은 대체로 효과적인 것으로 나타났다. 하지만 이와 같은 문제를 보이는 환자의 근본적인 원인인 근육 조절의 불균형을 바로잡는 재활훈련과 함께 이동된 위치에서 치열의 안정적인 적응을 위하여 구강주위 근육훈련이 병행되어야 한다.

• 대한소아치과학회지
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• 제38권2호
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• pp.181-186
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• 2011

자폐는 사회적 상호작용의 장애, 의사소통의 장애, 행동, 관심 및 활동이 한정되고 반복적이며 상동적인 양상을 나타내는 것으로 정의 될 수 있다. 자폐아의 경우 치과 치료시 협조를 얻어내는 것이 용이하지 않으며 자폐의 심도나 환아의 협조도 구강 상태 및 전신상태 등을 고려하여 행동 수정법, 약물을 이용한 진정요법, 전신마취 등을 통해 보다 효율적인 치과치료를 시행할 수 있다. 치과치료에 협조가 가능한 경증의 행동장애 또는 중등도의 행동장애를 보이는 경우 일반적인 행동 수정법과 진정요법으로 치료가 가능할수 있다. 그러나 환아의 협조도가 매우 불량하고 많은 양의 치과치료가 필요한 경우 한 번의 전신마취를 통해 환자는 여러번의 내원으로 인한 비용, 시간, 불안감을 줄일 수 있다. 본 증례는 충치치료를 주소로 연세대학교 원주기독병원 소아치과에 내원한 자폐로 진단받은 환아에서 각각의 자폐 심도에 따른 행동 조절법을 적용한 치과치료를 시행하고 다소의 지견을 얻었기에 보고하고자 한다.

• Archives of Plastic Surgery
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• 제36권3호
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• pp.306-310
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• 2009

Purpose: Owing to improvement of microscope, microsurgery implements, and microsuture, finger replantation has shown much development. With high success rate of microsurgery in children, positive results have been reported ever from distal amputation. Here, we report the patients demographics, methods, and results of the microsurgery performed in children in our hospital for the last 8 years. Methods: From the medical records of 21 patients who had given the treatment in our hospital from January 2000 to December 2007, we analyzed patients' sex, age, operative method, and complication retrospectively. Results: The number of male patients was twice as many as female, where most patients belong to the ages of five to ten years. Operative methods performed in this study included end - to - end anastomosis of artery and vein, vein graft, and epineurial suture. As a result, 19 out of 21 cases were successfully accomplished, and four of them went through the debridement of necrotic tissue due to the partial necrosis of the lesion. A one - year follow - up observation was done after surgery and most of them were almost fully recovered like in their previous state. Conclusion: The success rate of finger replantaion in children is continuously improving despite the difficulty of vessel anastomotic procedure, rehabilitation treatment and management after surgery. We report the satisfactory results of pediatric finger replantation technically and aesthetically.

• Clinical and Experimental Pediatrics
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• 제59권6호
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• pp.271-275
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• 2016

Purpose: A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-$Barr{\acute{e}}$ syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients. Methods: The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-wave abnormalities, and group B (n=26) exhibited normal findings. We compared laboratory reports, clinical features, response to treatment, and prognosis between the 2 groups. Results: Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulin treatment: 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflex abnormalities and poor prognosis compared with group B (P<0.05). Conclusion: This study demonstrated that F-waves are a clinically important prognostic factor in GBS. F-wave abnormalities were associated with abnormal DTR and poor prognosis in patients. Limited studies have examined the link between F-wave abnormalities and clinical results; therefore, further randomized controlled studies are needed to confirm the clinical characteristics and efficacy of treatments.

• Clinical and Experimental Pediatrics
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• 제54권1호
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• pp.22-28
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• 2011

Purpose: To investigate the clinical characteristics of late-onset epilepsy combined with autism spectrum disorder (ASD), and the relationship between certain types of electroencephalography (EEG) abnormalities in ASD and associated neuropsychological problems. Methods: Thirty patients diagnosed with ASD in early childhood and later developed clinical seizures were reviewed retrospectively. First, the clinical characteristics, language and behavioral regression, and EEG findings of these late-onset epilepsy patients with ASD were investigated. The patients were then classified into 2 groups according to the severity of the EEG abnormalities in the background rhythm and paroxysmal discharges. In the severe group, EEG showed persistent asymmetry, slow and disorganized background rhythms, and continuous sharp and slow waves during slow sleep (CSWS). Results: Between the two groups, there was no statistically significant difference in mean age (P=0.259), age of epilepsy diagnosis (P=0.237), associated family history (P=0.074), and positive abnormal magnetic resonance image (MRI) findings (P=0.084). The severe EEG group tended to have more neuropsychological problems (P=0.074). The severe group statistically showed more electrographic seizures in EEG (P=0.000). Rett syndrome was correlated with more severe EEG abnormalities (P=0.002). Although formal cognitive function tests were not performed, the parents reported an improvement in neuropsychological function on the follow up checkup according to a parent's questionnaire. Conclusion: Although some ASD patients with late-onset epilepsy showed severe EEG abnormalities, including CSWS, they generally showed an improvement in EEG and clinical symptoms in the longterm follow up. In addition, severe EEG abnormalities tended to be related to the neuropsychological function.

• 대한소아치과학회지
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• 제48권2호
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• pp.237-244
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• 2021

상아질형성부전증은 상아질 형성 이상이 초래되는 유전성 질환으로 상염색체 우성 형질을 따른다. 상아질형성부전증은 유치와 영구치 모두 이환되며, 다양한 치아 변색, 상아질 및 법랑질 파괴, 심한 치아마모 등의 임상소견을 보인다. 방사선학적으로 치아는 가느다란 치근과 둥그런 치과의 형태를 보이고 치수강은 적거나 폐쇄되었다. 상아질형성부전증의 치료는 추가적인 마모를 방지하고 수직고경 회복을 목표로 한다. 본 증례는 치아의 마모와 변색을 주소로 내원한 상아질형성부전증을 지닌 남매의 상이한 15년간의 장기 예후를 보고하고자 한다. 두 환자에서 치료개입 시기의 차이에 따라 상이한 치료과정을 볼 수 있다. 첫 번째 환아는 대부분의 본인 치아를 살렸으나, 두 번째 환아는 모든 치아를 발치하였다. 이는 상아질형성부전증의 조기 진단 및 치료방법 결정에 도움이 될 수 있다.

• 대한감각통합치료학회지
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• 제20권1호
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• pp.39-54
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• 2022

목적 : 본 연구는 아동 발달센터에서 근무하는 신입 작업치료사들이 감각통합치료 임상 적응과정에서 겪는 경험을 이해하고 본질을 파악하여 임상에서의 적응과정을 알아보고자 하였다. 연구방법 : 본 연구는 현상학적 연구 방법을 사용하였다. 참여자는 임상경험이 1년 미만인 4명이다. 자료수집은 심층 면담을 통해 진행하였으며 내용은 녹음 후 전사하여 분석하였다. 결과 : 아동 발달센터에서 근무하는 신입 작업치료사의 적응과정을 분석한 결과, 3가지 범주, 6가지 주제, 16개의 중심의미가 도출되었다. 범주로는 아동 발달센터에서 근무하는 신입 작업치료사는 적응과정을 겪으며 임상 실행에서 오는 어려움, 근무환경에서 오는 장애, 센터 내부에서의 긍정적 요소, 센터 외부에서 오는 지원, 스스로의 노력, 적응을 하며 바뀜을 경험하였다. 결론 : 아동 발달센터에서 감각통합치료를 하는 신입 아동 작업치료사들이 적응하여 충분한 역할을 수행할 수 있도록 기관과 주변의 도움이 필요할 것이다.

• 대한물리의학회지
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• 제13권1호
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• pp.27-38
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• 2018

PURPOSE: The purpose of this study was to find out the treatment patterns of Children with cerebral palsy, and to analyze the effect of physical function level and treatment intensity on improvement of physical function in children with cerebral palsy for six months. METHODS: Participants were 126 children (boys 83, girls 43) diagnosed cerebral palsy that the mean age was at 33months, ranged from 8 months to 77 months. We collected data related on demography and disable characteristic, treatment pattern using by questionnaire constructed ourselves for six months on caregivers. The treatment pattern includes, type, frequency, and institute of treatment. We performed the evaluation of Gross Motor Function Measurement (GMFM) and Pediatric Evaluation of Disability Inventory (PEDI) between pre and post for six months in order to find out improvement of physical function. We analyzed the effect of physical functional level measured by Gross Motor Functional Classification system, age, treatment intensity on physical function using by repeated measures ANOVA for SPSS PC ver. 22.0. RESULTS: The average of treatment frequency for physical therapy was 5.74 times per week, occupational therapy was 3.96 times, speech therapy was 2.96 times, treatment for accompanying disability was 3.12 times. Physical function level and age was significantly factors affecting improvement of physical function, there was no significant difference according to treatment intensity. CONCLUSION: We suggest that physical function and age might be important factors on improvement of physical function and professional rehabilitation team must consider the appropriate treatment type customized to each children.