• The Journal of Pediatrics of Korean Medicine
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• v.37 no.4
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• pp.70-90
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• 2023

Objective This study analyzed randomized clinical trials (RCTs) on pediatric asthma using traditional Chinese medicine (TCM) to determine its efficacy and safety. Methods We searched electronic databases in English, Chinese, Japanese, and Korean and evaluated 35 articles published up to December 28, 2022. Based on data from the literature, we analyzed treatments, results, composition of herbal medicine, frequency of medicinal herbs, and decoction. Results TCM for pediatric asthma was compared to supportive therapy, inhaled corticosteroids, and standardized treatments. Of the 35 studies, 32 showed that TCM treatments were effective in alleviating asthma symptoms. Furthermore, TCM treatment was considered safe compared to common asthma treatments. Among the TCM treatments for pediatric asthma, the most frequent decoctions were Gamisaganmahwangtang (加味射干麻黃湯) and Saganmahwangtang (射干麻黃湯). Ephedra Herba (麻黄), Armeniacae Semen (杏仁), Asiasari Radix et Rhizoma (細辛), Belamcandae Rhizoma (射干) were herbs that were frequently used for asthma in TCM decoctions. Conclusion This review showed that TCM is effective in treating pediatric asthma. More clinical RCTs are needed to confirm the efficacy and safety of TCM treatment.

• Clinical and Experimental Pediatrics
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• v.52 no.8
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• pp.843-850
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• 2009

A recent High Court's decision regarding the withdrawal of life supporting medical treatment (artificial ventilator) from an elderly female patient in the terminal stage has opened up a new era of the "euthanasia dispute" in Korea. With this decision, the legitimate withdrawal of life supporting treatment became possible under certain conditions and the Korean Medical Association is working toward the establishment of practical guidelines for the terminal-stage patients. However, there are still very few debates on the cases of pediatric patients in the terminal stage or suffering from fatal diseases. For pediatric patients, the core principle of autonomy and following procedure of "advance directives" are hardly kept due to the immaturity of the patients themselves. Decisions for their lives usually are in the hands of the parents, which may often bring out tragic disputes around "child abuse", especially in Korea where parents have exclusive control of the destiny of their children. Some developed countries such as the U.S.A., the U.K. and Canada have already established guidelines or a legal framework for ensuring the rights of the healthcare system regarding children suffering from severe illness, permitting the withdrawal of Life supporting medical treatment (LSMT) in very specific conditions when the quality of life of the children is severely threatened. For the protection of the welfare and interest of the children, we should discuss this issue and develop guidelines for the daily practice of pediatricians.

• Clinical and Experimental Pediatrics
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• v.45 no.4
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• pp.425-434
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• 2002

야뇨증은 소아뿐만 아니라 부모들에게 매우 애를 먹이는 현상이며, 때로는 정신적, 정서적 장애 또는 행동장애를 유발할 수도 있다. 적절한 치료를 하기 위하여서는 세심한 병력, 신체검사와 필요에 따라서 적절한 실험실 검사 및 방사선검사으로 단인증상성 야뇨증인지를 제대로 구별하여야 한다. 실제 임상에서 야뇨증의 치료는 그렇게 용이하지만은 않아 우선 어린이와 부모들이 야뇨증을 제대로 이해할 수 있도록 사전 교육을 통하여 적극적인 치료 의지를 갖도록 하는 것이 중요하다. 여러 가지 행동요법 및 야뇨경보기, 적절한 약물요법을 환자의 상황에 맞도록 적절한 치료 방법을 모색하여 보다 치료 효과가 높고 재발이 적도록 노력하여야 한다.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.3
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• pp.133-133
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• 2023

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.4
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• pp.16-33
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• 2021

Objectives This study aims to provide directions for future Korean pediatric medicine treatment and researches by analyzing the characteristics of diseases of Korean pediatric outpatients before and after the COVID-19 epidemic. Methods We analyzed the medical records of 10,868 new patients aged 0-18 who visited the Korean pediatrics at Kyung Hee university hospital from January 1, 2019 to June 30, 2021. All patients were divided into 2 groups; patients who visited from January 1, 2019 to December 31, 2019, before the coronavirus epidemic, and patients who visited from January 1, 2020 to June 30, 2021, after the coronavirus epidemic. Within the two groups, the diagnosis distribution was performed for the entire population, by gender and by age group. Diagnoses were classified as allergy, growth, gastrointestinal, respiratory, general body supplementation, neuropsychiatric, skin, urogenital, musculoskeletal, and other systems. Results According to the comparative analysis results of before and after the COVID epidemic, there was a decreasing trend of diagnoses in relates to allergy, respiratory, urogenital, musculoskeletal system. On the other side, there was an increasing trend in gastrointestinal, general body supplementation, growth, neuropsychiatric, skin and other system. Changes in diagnosis based on gender and age group will be described below. Conclusions This study analyzed the characteristics of diseases of Korean pediatric outpatients before and after the COVID-19 epidemic, and suggested the direction of future Korean medicine treatment and researches for pediatrics. Also, this study aimed to propose proper treatments for children by showing the role of Korean pediatric medicine related to growth and development of children during the epidemic. However, this study has limitations such as failure to track the long-term impact of COVID-19. Thus, long term follow-up studies are needed to show the effect of COVID-19 on Korean pediatric medicine.

• The Journal of Pediatrics of Korean Medicine
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• v.38 no.2
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• pp.11-20
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• 2024

Objectives We aimed to analyze menstrual pain clinical patterns and treatment characteristics in pediatric and adolescent patients under 18 years old treated for menstrual pain at a Korean medicine hospital. Methods We analyzed the medical records of pediatric and adolescent patients under 18, treated for menstrual pain from January 1, 2018, to December 31, 2023. Results A total of 88 participants were included in the study, with a mean age of 15.3 ± 1.5 years. The most common diagnosis was unspecified dysmenorrhea. Among the 42 participants with recorded pain scores, the mean Numeric Rating Scale (NRS) for dysmenorrhea was 7.4 ± 1.0. Patients who received two or more treatments had an average of 6.3 ± 5.0 clinic visits. Treatment methods included herbal medicine, acupuncture, moxibustion, pharmacopuncture, and electroacupuncture, in descending order of frequency. Conclusions It is necessary to analyze the clinical characteristics and status of adolescent dysmenorrhea patients in more Korean medical institutions. Additionally, research and promotion of Korean medicine treatments for adolescent dysmenorrhea are needed.

• The Journal of Pediatrics of Korean Medicine
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• v.18 no.1
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• pp.165-177
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• 2004

Objective : The purpose of this study is to report a pediatric patient combined some peculiar diseases of nervous system in childhood. Methods : The patient with preceding five kinds of retardation developed five kinds of flaccidity and five kinds of spasticity after chronic infantile convulsion. We treated the progress of her condition, measured spasticity of both leg by MAS(Modified Ashworth Scale). Results and Conclusion: The general condition of patient, symptoms of five kinds of flaccidity and MAS grade of both leg spasticity had been improved. And so this study requires further studies about peculiar diseases of nervous system in childhood.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.3
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• pp.1-10
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• 2006

Objectives : The purpose of this study is to report a pediatric patient with five retardations and five flaccidities caused by hydrocephalus treated with oriental medicine. Methods : We performed an ambulatory treatment for him with herb medicine, acupuncture. And we measured grade of sitting, standing, walking, speaking. Results : The child's sitting, standing time increased from zero second to one-two minutes, and speaking improved. Conclusions : We report the good results of oriental medical treatment on this case. And this study requires further studies about five retardations and five flaccidities caused by hydrocephalus.

• Clinical and Experimental Pediatrics
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• v.64 no.9
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• pp.436-442
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• 2021

This article aimed to summarize the impact and burden of pediatric postintensive care syndrome (PICS-p) in the physical, mental, cognitive, and social health domains after a review of the current pediatric literature in MEDLINE and PubMed. We also aimed to elucidate the limitations of the current evaluation tools used in limited-resource settings. PICS-p can impact a child's life for decades. Most validated tools are time-consuming, require qualifications, and expertise, are often limited to older children, and can evaluate only one domain. A novel, simple, and comprehensive surveillance tool can aid healthcare providers in the early detection and intervention of PICS-p. Further studies should validate and refine the parameters that will enhance the outcomes of pediatric intensive care unit survivors.

• Clinical and Experimental Pediatrics
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• v.65 no.2
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• pp.56-64
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• 2022

Cerebrospinal fluid (CSF) is a dynamic metabolically active body fluid that has many important roles and is commonly analyzed in pediatric patients, mainly to diagnose central nervous system infection and inflammation disorders. CSF components have been extensively evaluated as biomarkers of neurological disorders in adult patients. Circulating microRNAs in CSF are a promising class of biomarkers for various neurological diseases. Due to the complexity of pediatric neurological disorders and difficulty in acquiring CSF samples from pediatric patients, there are challenges in developing CSF biomarkers of pediatric neurological disorders. This review aimed to provide an overview of novel CSF biomarkers of seizure disorders, infection, inflammation, tumor, traumatic brain injuries, intraventricular hemorrhage, and congenital hydrocephalus exclusively observed in pediatric patients.