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Efficacy of carprofen administration and rehabilitative intervention in a dog with unilateral forelimb lameness (편측 앞다리 파행이 있는 개에서 카프로펜 투여와 재활 중재의 효과)

  • Shin-Ho Lee;Sujin Kim;Jae-Hyeon Cho
    • Korean Journal of Veterinary Service
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    • v.47 no.3
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    • pp.185-191
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    • 2024
  • This case report examines the efficacy of carprofen and rehabilitation therapy in a 7-year-old, 4.5 kg, spayed Poodle with unilateral forelimb lameness. Gait analysis assessed kinetic parameters such as peak vertical force (PVF), vertical impulse (VI), symmetry index (SI), and body load distribution (BLD) before and after treatment. The differences between the left and right forelimbs were recorded. Before intervention, the PVF differences between the forelimbs were -4.00% during walking and 40.00% during trotting. Two weeks post-intervention, these improved to 8.33% and 27.67%, further reducing to 6.33% and 18.00% after four weeks. VI differences also improved, with initial values of -0.67 N∙s during walking and -1.3 N∙s during trotting decreasing to -0.03 N∙s and -0.87 N∙s, respectively. SI increased from 6.23% to 11.87% during walking, while it decreased from 33.63% to 14.73% during trotting. BLD differences reduced from -1.17 cm2 and -7.13 cm2 to 0.23 cm2 and -2.17 cm2, respectively, after four weeks. These results suggest that a combination of carprofen administration and rehabilitative intervention can effectively reduce lameness and improve symmetry in dogs with unilateral forelimb lameness, as evidenced by improvements in key gait parameters over the treatment period.

A Study on the Gonadal Maturation and Egg-Stripping by Hormone Treatments of Tiger Puffer, Takifugu rubripes (자주복, Takifugu rubripes의 성성숙과 호르몬 처리에 의한 인공채란에 관한 연구)

  • YANG Sang-Geun;LEE Young-Don;PYEN Choong-Kyu
    • Journal of Aquaculture
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    • v.7 no.4
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    • pp.189-205
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    • 1994
  • Formerly, adult-tiger puffer, Takifugu rubripes with ova caught in the sea, were used for seedling production. But it was difficult to secure naturally-ripened adults. For the purpose of adult tiger puffer in captivity, this study was carried out. To determine the growth 220 tiger puffers hatched in 1990 (3-year-old) and 1991 (2-year-old) were used. For spawning and egg incubation leading to fry development, eggs were stripped from tiger puffers hatched in 1988 (5-year-old) and 1990 (3-year-old) through human chorionic gonadotropin (BCG) treatments. In May, 1993, mean body length and mean body weight of 2-year-old tiger puffer were $30.72\pm1.35cm\;and\;1,048\pm228 g,$ and that of 3-year-old tiger puffers were $36.02\pm1.17cm$ and $1,402\pm66g$ respectively. The relationship between body length (L) and body weight (W) of 2-year-old the tiger puffers during the experiment period was represented as $W\;=\;1.7892L^{31524}\times10^5$ (r= 0.9436) and that of 3-year-old, $W=\;3.2840L^{36099}\times10^6$ (r= 0.9070) respectively. The GSI in female 2-year-old-fish changed from $0.23\times0.l2\;to\;0.74\pm0.08$, during the experiment period, and in male it didn't change remarkably until November, but thereafter it increased and showed a peak of $8.69\pm5.09$. The GSI of 3-year-old-fish showed a peak of $8.05\pm5.58$ in April in female and $12.65\pm4.60$ in May in male. The change of HSI in 3-year-old-fish was correlative to the change of GSI, but in 2-year-old-fish it was little correlative. In female gonad of 2-year-old tiger puffer, the mature oocytes reached $350{\mu}m$ in April, but thereafter they didn't spawn and became atrophied. But in male gonad, a great number of spermatozoa were crowded in the testicular lobuli in April. Female gonad of 3-year-old tiger puffer had the mature oocytes of 650 pm in March and the ripe oocytes, $900{\mu}m$ in April. Male testis development was similar to that of 2-year-old-fish. Egg-stripping after hormone treatments was possible past 139 hours and 142 hours from each of two 5-year-old-fish (500IU/kg, BW), and after 114 hour from a 3-year-old-fish (1,000 IU/kg, BW) under water temperature $16.3\~17.8^{\circ}C$. Eggs stripped amounted was 650 g and 400 g from two 5-year-old-fish and 610 g from the 3-year-old-fish, and fertilization rates were $98.0\%,\;97.4\%\;and\;96.5\%$ respectively. All the hatched larvae devloped into normal fry.

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Development of Movement Analysis Program and its Feasibility Test in Streotactic Body Radiation Threrapy (복부부위의 체부정위방사선치료시 호흡에 의한 움직임분석 프로그램 개발 및 유용성 평가)

  • Shin, Eun-Hyuk;Han, Young-Yih;Kim, Jin-Sung;Park, Hee-Chul;Shin, Jung-Suk;Ju, Sang-Gyu;Lee, Ji-Hea;Ahn, Jong-Ho;Lee, Jai-Ki;Choi, Doo-Ho
    • Progress in Medical Physics
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    • v.22 no.3
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    • pp.107-116
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    • 2011
  • Respiratory gated radiation therapy and stereotactic body radiation therapy require identical tumor motions during each treatment with the motion detected in treatment planning CT. Therefore, this study developed a tumor motion monitoring and analysis system during the treatments employing RPM data, gated setup OBI images and a data analysis software. A respiratory training and guiding program which improves the regularity of breathing was used to patients. The breathing signal was obtained by RPM and the recorded data in the 4D console was read after treatment. The setup OBI images obtained gated at 0% and 50% of breathing phases were used to detect the tumor motion range in crenio-caudal direction. By matching the RPM data recorded at the OBI imaging time, a factor which converts the RPM motion to the tumor motion was computed. RPM data was entered to the institute developed data analysis software and the maximum, minimum, average of the breathing motion as well as the standard deviation of motion amplitude and period was computed. The computed result is exported in an excel file. The conversion factor was applied to the analyzed data to estimate the tumor motion. The accuracy of the developed method was tested by using a moving phantom, and the efficacy was evaluated for 10 stereotactic body radiation therapy patients. For the sine wave motion of the phantom with 4 sec of period and 2 cm of peak-to-peak amplitude, the measurement was slightly larger (4.052 sec) and the amplitude was smaller (1.952 cm). For patient treatment, one patient was evaluated not to qualified to SBRT due to the usability of the breathing, and in one patient case, the treatment was changed to respiratory gated treatment due the larger motion range of the tumor than treatment planed motion. The developed method and data analysis program was useful to estimate the tumor motion during treatment.

Growth and Production of Mactra veneriformis (Bivalvia) on the Songdo Tidal Flat, West Coast of Korea (서해 송도 갯벌에서의 동죽(Mactra veneriformis: Bivalvia)의 성장과 생산)

  • 신현출;고철환
    • 한국해양학회지
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    • v.30 no.5
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    • pp.403-412
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    • 1995
  • The present study was performed to determine th growth and production of Mactra veneriformis on the Songdo tidal flat off Inchon. west coast of Korea. Monthly samples were collected from Marc 1989 to September 1990. The size distributions of shell length showed unimodal patterns from March to August 1989. The binodal pattern after September 1989 indicated a recruitment of young clams during this period. The density fluctuated irregularly, but showed a decreasing pattern over time on the whole. The density of the year class 1989 increased markedly after February 1990. The growth in shell length showed three phases during a year, a fast growth phase in spring, a slow growth phase in summer and autumn, and a lag phase in winter. The annual increment in shell length reduced with age. The flesh dry weight showed a peak in late spring just before the spawning period, and another peak in autumn. The length of annuli and the back-calculated flesh dry weight were used to describe the annual growth. The growth in shell length fitted to the von Bertalanffy model and the flesh dry weight to the Gompertz model. The absolute growth rate of the shell length reduced gradually with age. The year class 1985 had the highest L, and the yeat class 1986 the lowest L. The annual growth in weight showed a typical sigmoid curve. The growth rate was maximum at the age of 2 to 3. Year classes of 1984 and 1985 had higher values of W and higher absolute growth rates than those of 1986 and 1987. Maximum absolute growth rates of 1986 and 1987 year classes were recorded at younger ages than 1984 and 1985 year classes. The annual relative growth rates of length and weight decreased exponentially with age. Biomass in flesh dry weight increased till spring and thereafter decreased progressively. Maximum biomass was 134.6g m/SUP -2/ in August 1990. The biomass of 1989 yeat class occupied highest proportion in total biomass. Annual production in flesh dry weight from March 1989 to March 1990 was 67.9 g m/SUP -2/ year/SUP -1/. Cumulative production of 1989 year class was highest among all year classes, and that of year class 1984 was lowest. The production is high in spring and autumn, and very low in summer and winter.

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Measurement of Turbulence Properties at the Time of Flow Reversal Under High Wave Conditions in Hujeong Beach (후정해변 고파랑 조건하에서 파랑유속 방향전환점에서 발생하는 난류성분의 측정)

  • Chang, Yeon S.;Do, Jong Dae;Kim, Sun-Sin;Ahn, Kyungmo;Jin, Jae-Youll
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.29 no.4
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    • pp.206-216
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    • 2017
  • The temporal distribution of the turbulence kinetic energy (TKE) and the vertical component of Reynolds stresses ($-{\bar{u^{\prime}w^{\prime}}}$) was measured during one wave period under high wave energy conditions. The wave data were obtained at Hujeong Beach in the east coast of Korea at January 14~18 of 2017 when an extratropical cyclone was developed in the East Sea. Among the whole thousands of waves measured during the period, hundreds of regular waves that had with similar pattern were selected for the analysis in order to give three representing mean wave patterns using the ensemble average technique. The turbulence properties were then estimated based on the selected wave data. It is interesting to find out that $-{\bar{u^{\prime}w^{\prime}}}$ has one clear peak near the time of flow reversal while TKE has two peaks at the corresponding times of maximum cross-shore velocity magnitudes. The distinguished pattern of Reynolds stress indicates that vertical fluxes of such properties as suspended sediments may be enhanced at the time when the horizontal flow direction is reversed to disturb the flows, supporting the turbulence convection process proposed by Nielsen (1992). The characteristic patterns of turbulence properties are examined using the CADMAS-SURF Reynolds-Averaged Navier-Stokes (RANS) model. Although the model can reasonably simulate the distribution of TKE pattern, it fails to produce the $-{\bar{u^{\prime}w^{\prime}}}$ peak at the time of flow reversal, which indicates that the application of RANS model is limited in the prediction of some turbulence properties such as Reynolds stresses.

Effects of Ambient Particulate Matter($PM_{10}$) on Peak Expiratory Flow and Respiratory Symptoms in Subjects with Bronchial Asthma During Yellow Sand Period (황사기간 중 천식 환자에서 대기 중 미세먼지($PM_{10}$)가 최대호기 유속과 호흡기 증상에 미치는 영향)

  • Park, Jeong Woong;Lim, Young Hee;Kyung, Ssun Young;An, Chang Hyeok;Lee, Sang Pyo;Jeong, Seong Hwan;Ju, Young-Su
    • Tuberculosis and Respiratory Diseases
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    • v.55 no.6
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    • pp.570-578
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    • 2003
  • Background : Ambient particles during Asian dust events are usually sized less than $10{\mu}m$, known to be associated with the adverse effects on the general populations. But, there has been no considerable evidence linking these particles to the adverse effects on airways. The objectives of this study was to investigate the possible adverse effects of Asian dust events on respiratory function and symptoms in subjects with bronchial asthma. Patients and Methods : From march to June 2002, Asthmatic patients who were diagnosed with bronchial challenge test or bronchodilator response were enrolled. We divided them into three groups; mild, moderate, and severe, according to the severity. Subjects with other organ insufficiency such as heart, kidney, liver, and malignancy were excluded. All patients completed twice daily diaries and recorded peak flow rate, respiratory symptom, and daily activity. Daily and hourly mean pollutant levels of particulate matter < $10{\mu}m$ in diameter($PM_{10}$), nitrogen dioxide($NO_2$), sulphur dioxide($SO_2$), ozone($O_3$) and carbon monoxide(CO) were measured at the 10 different monitoring sites. Results : Dust events occured 14 times during the study period. Daily averages of 4 air pollutant were measured with an increased level of $PM_{10}$, decreased level of $NO_2$ and $SO_2$, and no change in CO during dust days compared to those during control days. An increase in $PM_{10}$ concentration was associated with an increase of subjects with PEF variability of >20% (p<0.05), night time symptom(p<0.05), and a decrease in mean PEF (p<0.05), which were calculated by the longitudinal data analysis. Otherwise, there was no association between $PM_{10}$ level and bronchodialtor inhaler, and daytime respiratory symptoms. Conclusion : This study shows evidence that ambient air pollution, especially $PM_{10}$, during Asian dust events, could be one of the many aggravating factors at least in patients with airway diseases. This data can be used as a primary source to set up a new policy on air environmental control and to evaluate the safety of air pollution index. We also expect that this research will help identify precise components of dust, which are more linked to the adverse effects.

Biological characteristics of Phanuromyia ricaniae(Hemiptera: Platygastroidea), an egg parasitoid of Ricania sublimata (Hemiptera: Ricaniidae) (갈색날개매미충 알 기생봉인 날개매미충알벌(Phanuromyia ricaniae)의 생물 특성)

  • Jeon, Sung-Wook;Kim, Kwang-Ho;Lee, Gwan-Seok;Seo, Bo Yoon;Kim, Ji Eun;Kang, Wee Soo;Cho, Jum Rae
    • Korean Journal of Environmental Biology
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    • v.38 no.4
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    • pp.586-593
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    • 2020
  • This study was conducted to investigate the biological characteristics of Phanuromyia ricaniae (Hemiptera: Platygastroidea), an egg parasitoid of Ricania sp. (Hemiptera: Ricaniidae) as a biological control agent to control Ricania sublimata. The developmental period of P. ricaniae was 3.8 days for eggs, 11.1 days for larvae, and 16.3 days for pupae at 25℃, and 3.4 days for eggs, 7.8 days for larvae, and 15.3 days for pupae at 30℃. Except for the larval stage, the developmental periods were not significantly different, but the egg-to-pupa period at 30℃ was significantly shorter than that at 25℃. P. ricaniae emerged at the photophase in 24 hours, but not at the scotophase. A higher emergence rate (34.5%) was seen from 10:00 to 12:00 after the lights were turned. The female-to-male ratio of P. ricaniae was 3:1. The longevity of P. ricaniae adults was 49.0 days for females and 44.0 days for males at 20℃, 27.6 days for females and 28.4 days for males at 25℃, and 18 days for females and 14.0 days for males at 30℃. Its longevity at a low temperature (20℃) was longer than that at higher temperatures (25 and 30℃). Adult females laid eggs during all days except from 00:00-02:00 (scotophase time). The ovipositional distribution rate was 26.1% from 20:00 to 22:00, which was the peak, and the next peak was 15.7% at 10:00 to 12:00. P. ricaniae showed arrhenotokous parthenogenesis in which unfertilized eggs develop into males. Therefore, the results suggest that P. ricaniae may be a biological control agent for R. sublimata.

Clinical Analysis of Surgical Results for Discrete Subaortic Stenosis (분리 대동맥판막하 협착증 수술의 임상적 고찰)

  • Yu Song Hyeon;Lim Sang Hyun;Hong You Sun;Park Young Hwan;Chang Byung Chul;Kang Meyun Shick
    • Journal of Chest Surgery
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    • v.38 no.8 s.253
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    • pp.545-550
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    • 2005
  • Background: Discrete subaortic stenosis is known to recur frequently even after surgical resection. We retrospectively reviewed the preoperative and postoperative changes in pressure gradient through left ventricular outflow tract, and the recurrence rate. Material and Method: Between September 1984 and December 2004, 34 patients underwent surgical treatment. Mean age of patients was $17.1\pm15.2$ years and 19 patients $(55.9\%)$ were male, 16 patients $(47.1\%)$ had previous operations and associated diseases were aortic regurgitation (11), coarctation of aorta (3), and others. Result: Immediate postoperative peak pressure gradient was significantly lower than preoperative peak pressure gradient (21.8 mmHg vs 75.8 mmHg, p<0.04). Peak pressure gradient measured after 50.3 months of follow up was 20.2 mmHg which was also significantly lower than that of preoperative value but not significantly different from that of immediate postoperative value. There was no surgical mortality but one patient developed cerebral infarction. Mean follow up duration was $69.8\pm54.6\;months$. During this period, 5 patients $(14.7\%)$ had reoperation, 3 $(8.8\%)$ of whom were due to recurred subaortic stenosis. We found no risk factors for recurrence and survival for free from reoperation was $76.4\%$. Conclusion: Excision of subaortic membrane combined with or without myectomy in discrete subaortic stenosis showed sufficient relief of left ventricular outflow tract obstruction with low mortality and morbidity, but careful long term follow up is necessary for recurrence, since it is not predictable.

Ultrastructrual Change of Myocardium in Open Cardiac Surgery with Cold Blood Cardioplegia (개심술 시 냉혈성 심정지액 사용에 따른 허혈 전후 심근 미세구조의 변화)

  • 김병호;김대현;공준혁;조준용;손윤경;이종태
    • Journal of Chest Surgery
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    • v.36 no.9
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    • pp.638-645
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    • 2003
  • The purposes of this study were to evaluate the effect of myocardial protection with our cold blood cardioplegic solution and to observe the relationship between ultrastructural study and other evaluation methods and its effectiveness. Material and Method: We evaluated the changes of myocardial ultrastructure using semi-quantitative scoring system, CK-MB fraction, SGOT and LDH1/LDH2, and EKG in 18 patients undergoing valvular heart surgery and coronary artery bypass grafting (CABG). Right atrial auricular biopsies were taken before the cardiopulmonary bypass (CPB) and shortly after the end of CPB. Myocardium-related serum enzymes & EKG were checked for 3 days of postoperative period and their postoperative peak enzyme value and observed new Q wave & ST segment elevation in EKG were choosen. Result: There were 8 males and 10 females, and their mean age was 55.6$\pm$13. Eight patients underwent valvular heart surgery and ten coronary artery bypass grafting, The mean CPB time was 119$\pm$29 minutes and the mean aortic cross-clamp (ACC) time was 75.4$\pm$24 minutes. Before the start of CPB, the mean mitochondrial score was 4.28$\pm$0.53 and after the end of CPB, it significantly increased to 2.35$\pm$0.79. There was no evidence of perioperative myocardial infarction in terms of myocardiumrelated serum enzyme value and Q wave and ST change in EKG. There was no significant relationship between pre-CPB and post-CPB mitochondrial score and the mean time of CPB and ACC, and the mean value of postoperative peak CK-MB, SGOT and LDH1/LDH2, but there was relatively positive correlation of CPB time with peak LDH1/LDH2. Conclusion: Despite the apparent satisfactory results in myocardium-related serum enzymes & EKG, with this study using the cold blood cardioplegic solution, there were many changes in myocardial ultrastructures, and more studies are needed to obtain further information.

Clinical Analysis of the Pediatric Patients Seen in the Emergency Medical Center (응급의료센터 소아 환자들의 경향 분석)

  • Lee, Hee Jung;Park, So Yoon;Lee, Young Hwan;Do, Byung Soo;Lee, Sam Bum
    • Clinical and Experimental Pediatrics
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    • v.48 no.10
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    • pp.1061-1067
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    • 2005
  • Purpose : We studied a clinical analysis of pediatric patients who visited the emergency medical center of Yeungnam University Hospital to compare the characteristics of pediatric emergency patients after year 2000 with the previous studies. Methods : We reviewed 7,034 children under the age of 15 years who visited the emergency medical center of Yeungnam University Hospital during the 2 year period from January 2001 to December 2002, and then we performed a clinical and statistical analysis. We analyzed the pediatric patients according to gender, age, season, day of the week, time of the visit, the disease classification and the final disposition of the patients. Results : Among the patients who visited the emergency room, 15.6% of the total emergency patients were under the age of 15. The male to female ratio was 1.6 : 1. Among the 7,034 pediatric patients, the most common age group was between 1 year and under 3 years of age(26.9%). The peak seasonal incidence was early summer and spring, especially during June(11.2%) and May(10.6 %). The peak incidence day of the week was Sunday(24.8%) and the peak time when the emergency pediatric patients visited the emergency room was between 20 and 24 o'clock(28.8%). The distribution of diseases, according to ICD-10 system, were injury and poisoning(30.4%), diseases of the respiratory system(22.8%), and diseases of the digestive system(14.6%). 30% of total pediatric patients were admitted to the hospital. Conclusion : After year 2000, as compared with the previous studies, the proportions of emergency pediatric patients has decreased. The distribution of diseases was not much different from the previous studies and the proportions of non-urgent diseases, such as acute nasopharyngitis or acute gastroenteritis, were still high. These result have come about due to the declining birth rate and changes of the medical system in Korea.