• Title/Summary/Keyword: Peak Sum

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Changes of Interleukin-10 level in Patients Undergoing cardiopulmonary Bypass (체외순환에 따른 혈중 Interleukin-10의 변화)

  • 홍남기;이동협;정태은;이정철;한승세
    • Journal of Chest Surgery
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    • v.33 no.8
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    • pp.648-654
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    • 2000
  • Background: Cardiopulmonary bypass during open heart surgery causes systemic inflammatory respose. IL-10 is an anti-inflammatory cytokine that inhibits inflammatory process and protects organ function by down regulation of pro-inflammatory cytokine release and maintenance of blood level balance with pro-inflammatory cytokines. Mateial and Method: Plasma IL-10 levels were measured and analyzed in 22 patients who underwent open heart surgery (11 cases of coronary artery bypass graft, 11 cases of valve replacement) under cardiopulmonary bypass since 1988 January to July at Department of Thoracic and Czardiovascular surgery, Yeungnam University Hospital. 1g of methylprednisolone was administrated to thirteen patients randomly. Blood samp.es were taken and collected at the time of induction of anesthesia, 10 min before cardiopulmonary bypass, 10 min after starting of CPB, 10 min aftr aortic cross clamping, 10 min after ACC release, and 10 min, 2 hours, and `5 hours after CPB respectively. The plasma levels of IL-10 were determined by enzyme-linked immunosorbent assays(ELISA). Wilcoxon-Raule Sum test was used for statistical analysis. Result: In all 22 patients, cardiopulmonary bypass time was used for statistical analysis. Result: In all 22 patients, cardiopulmonary bypass time was 171$\pm$41.4 min and aortic cross clamp time was 118$\pm$36.5 min. Peak IL-10 level was achieved at 10 min after ACC(361.0$\pm$52.81pg/ml) and was decreased sharply at 2 hours after CPB. Peak IL-10 level was correlated positively with aortic cross clamp time(p=0.011); however, it did not correlated with bypass time(p=0.181). In valve replacement group, mean IL-10 level at peak point was 567.89$\pm$107.69 pg/ml and was significantly higher than that of coronary artery bypass group(205.67$\pm$192.70 pg/ml)(p<0.001). ACC time in valve replacement group was significantly longer than that of coronary artery bypass group(p<0.01), however, bypass time was not(p=0.212). Thirteen patients with steroid pretreatment before starting of CPB showed relatively higher plasma IL-10 level than in control group, however, no statistical significance was noted(p=0.19). Conclusion: plasma level of IL-10 was increased in association with cardiopulmonary bypass and revealed peak at 10 min after ACC release. IL-10 level was correlated positively with ACC time. Therefore, systemic inflammatory respeonse in association with cardiopulmonary bypass could be decreased by reducing ACC time during cardiac surgery.

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Analysis on Efficiency of Hierarchical Structure for a Grid Transit Network (격자형 대중교통 노선망의 위계구조 효율성 분석)

  • Park, Jun-Sik;Go, Seung-Yeong;Jeon, Gyeong-Su
    • Journal of Korean Society of Transportation
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    • v.25 no.4
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    • pp.123-133
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    • 2007
  • This study analyzed whether a transit network with hierarchy is efficient or not, and if transit network hierarchy has cost efficiency, then which condition guarantees the efficiency of the transit network hierarchy. The authors modeled the total cost of the transit network and suggested the conditions in which the transit network hierarchy has cost efficiency through comparing the cost of the transit network with and without hierarchy. The efficiency of transit network hierarchy is guaranteed when the travel cost savings induced by using a higher hierarchy transit network is larger than the increasing non-travel cost, which is the sum of access cost, waiting cost, and operating cost, induced by the introduction of a higher hierarchy transit network. This result is consistent with common sense and with the concept of cost and benefit analysis. If a passenger traveling within the area divided by a higher hierarchy transit network uses only a lower hierarchy transit network and the passenger traveling out of the area divided by the higher hierarchy transit network uses both lower and higher hierarchy transit networks, the travel demand using the higher hierarchy transit network is inversely proportional to the square of the line spacing. This means that the transit network becomes more efficient and small increases of travel demand guarantee the efficiency of the transit network hierarchy as the connectivity of the network becomes higher. This result shows that transit networks have economies of aggregation. This study is the first analytical research on transit network hierarchy and is expected to be a basis for numerical research. However, numerical research should complement this study, since analytical research has some limitations for considering a real network.

Stereospecific Analysis of the Molecular Species of the Triacylglycerols Containing Conjugate Trienoic Acids by GLC-Mass Spectrometry in Combination with Deuteration and Pentafluorobenzyl Derivatization Techniques (중수소화(重水素化), Pentafluorobenzyl화(化)와 GLC-Mass Spectrometry에 의한 Conjugate Trienoic Acid함유(含有) Triacylglycerol 분자종(分子種)의 입체특이적 분석(分析))

  • Woo, Hyo-Kyeng;Kim, Seong-Jin;Joh, Yong-Goe
    • Journal of the Korean Applied Science and Technology
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    • v.18 no.3
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    • pp.214-232
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    • 2001
  • CTA ester bonds in TG molecules were not attacked by pancreatic lipase and lipases produced by microbes such as Candida cylindracea, Chromobacterium viscosum, Geotricum candidium, Pseudomonas fluorescens, Rhizophus delemar, R. arrhizus and Mucor miehei. An aliquot of total TG of all the seed oils and each TG fraction of the oils collected from HPLC runs were deuterated prior to partial hydrolysis with Grignard reagent, because CTA molecule was destroyed with treatment of Grignard reagent. Deuterated TG (dTG) was hydrolyzed partially to a mixture of deuterated diacylglycerols (dDG), which were subsequently reacted with (S)-(+)-1-(1-naphthyl)ethyl isocyanate to derivatize into dDG-NEUs. Purified dDG-NEUs were resolved into 1, 3-, 1, 2- and 2, 3-dDG-NEU on silica columns in tandem of HPLC using a solvent of 0.4% propan-1-o1 (containing 2% water)-hexane. An aliquot of each dDG-NEU fraction was hydrolyzed and (fatty acid-PFB ester). These derivatives showed a diagnostic carboxylate ion, $(M-1)^{-}$, as parent peak and a minor peak at m/z 196 $(PFB-CH_{3})^{-}$ on NICI mass spectra. In the mass spectra of the fatty acid-PFB esters of dTGs derived from the seed oils of T. kilirowii and M. charantia, peaks at m/z 285, 287, 289 and 317 were observed, which corresponded to $(M-1)^{-}$ of deuterized oleic acid ($d_{2}-C_{18:0}$), linoleic acid ($d_{4}-C_{18:0}$), punicic acid ($d_{6}-C_{18:0}$) and eicosamonoenoic acid ($d_{2}-C_{20:0}$), respectively. Fatty acid compositions of deuterized total TG of each oil measured by relative intensities of $(M-1)^-$ ion peaks were similar with those of intact TG of the oils by GLC. The composition of fatty acid-PFB esters of total dTG derived from the seed oils of T. kilirowii are as follows; $C_{16:0}$, 4.6 mole % (4.8 mole %, intact TG by GLC), $C_{18:0}$, 3.0 mole % (3.1 mole %), $d_{2}C_{18:0}$, 11.9 mole % (12.5 mole %, sum of $C_{18:1{\omega}9}$ and $C_{18:1{\omega}7}$), $d_{4}-C_{18:0}$, 39.3 mole % (38.9 mole %, sum of $C_{18:2{\omega}6}$ and its isomer), $d_{6}-C_{18:0}$, 41.1 mole % (40.5 mole %, sum of $C_{18:3\;9c,11t,13c}$, $C_{18:3\;9c,11t,13r}$ and $C_{18:3\;9t,11t,13c}$), $d_{2}-C_{20:0}$, 0.1 mole % (0.2 mole % of $C_{20:1{\omega}9}$). In total dTG derived from the seed oils of M. charantia, the fatty acid components are $C_{16:0}$, 1.5 mole % (1.8 mole %, intact TG by GLC), $C_{18:0}$, 12.0 mole % (12.3 mole %), $d_{2}-C_{18:0}$, 16.9 mole % (17.4 mole %, sum of $C_{18:1{\omega}9}$), $d_{4}-C_{18:0}$, 11.0 mole % (10.6 mole %, sum of $C_{18:2{\omega}6}$), $d_{6}-C_{18:0}$, 58.6 mole % (57.5 mole %, sum of $C_{18:3\;9c,11t,13t}$ and $C_{18:3\;9c,11t,13c}$). In the case of Aleurites fordii, $C_{16:0}$; 2.2 mole % (2.4 mole %, intact TG by GLC), $C_{18:0}$; 1.7 mole % (1.7 mole %), $d_{2}-C_{18:0}$; 5.5 mole % (5.4 mole %, sum of $C_{18:1{\omega}9}$), $d_{4}-C_{18:0}$ ; 8.3 mole % (8.5 mole %, sum of $C_{18:2{\omega}6}$), $d_{6}-C_{18:0}$; 82.0 mole % (81.2 mole %, sum of $C_{18:3\;9c,11t,13t}$ and $C_{18:3 9c,11t,13c})$. In the stereospecific analysis of fatty acid distribution in the TG species of the seed oils of T. kilirowii, $C_{18:3\;9c,11t,13r}$ and $C_{18:2{\omega}6}$ were mainly located at sn-2 and sn-3 position, while saturated acids were usually present at sn-1 position. And the major molecular species of $(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13c})_{2}$ and $(C_{18:1{\omega}9})(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13c})$ were predominantly composed of the stereoisomer of $sn-1-C_{18:2{\omega}6}$, $sn-2-C_{18:3\;9c,11t,13c}$, $sn-3-C_{18:3\;9c,11t,13c}$, and $sn-1-C_{18:1{\omega}9}$, $sn-2-C_{18:2{\omega}6}$, $sn-3-C_{18:3\;9c,11t,13c}$, respectively, and the minor TG species of $(C_{18:2{\omega}6})_{2}(C_{18:3\;9c,11t,13c})$ and $ (C_{16:0})(C_{18:3\;9c,11t,13c})_{2}$ mainly comprised the stereoisomer of $sn-1-C_{18:2{\omega}6}$, $sn-2-C_{18:2{\omega}6}$, $sn-3-C_{18:3\;9c,11t,13c}$ and $sn-1-C_{16:0}$, $sn-2-C_{18:3\;9c,11t,13c}$, $sn-3-C_{18:3\;9c,11t,13c}$. The TG of the seed oils of Momordica charantia showed that most of CTA, $C_{18:3\;9c,11t,13r}$, occurred at sn-3 position, and $C_{18:2{\omega}6}$ was concentrated at sn-1 and sn-2 compared to sn-3. Main TG species of $(C_{18:1{\omega}9})(C_{18:3\;9c,11t,13t})_{2}$ and $(C_{18:0})(C_{18:3\;9c,11t,13t})_{2}$ were consisted of the stereoisomer of $sn-1-C_{18:1{\omega}9}$, $sn-2-C_{18:3\;9c,11t,13t}$, $sn-3-C_{18:3\;9c,11t,13t}$ and $sn-1-C_{18:0}$, $sn-2-C_{18:3\;9c,11t,13t}$, $sn-3-C_{18:3\;9c,11t,13t}$, respectively, and minor TG species of $(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13c})_{2}$ and $(C_{18:1{\omega}9})(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13c})$ contained mostly $sn-1-C_{18:2{\omega6}$, $sn-2-C_{18:3\;9c,11t,13t}$, $sn-3-C_{18:3\;9c,11t,13t}$ and $sn-1-C_{18:1{\omega}9}$, $sn-2-C_{18:2{\omega}6}$, $sn-3-C_{18:3\;9c,11t,13t}$. The TG fraction of the seed oils of Aleurites fordii was mostly occupied with simple TG species of $(C_{18:3\;9c,11t,13t})_{3}$, along with minor species of $(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13t})_{2}$, $(C_{18:1{\omega}9})(C_{18:3\;9c,11t,13t})_{2}$ and $(C_{16:0})(C_{18:3\;9c,11t,13t})$. The sterospecific species of $sn-1-C_{18:2{\omega}6}$, $sn-2-C_{18:3\;9c,11t,13t}$, sn-3-C_{18:3\;9c,11t,13t}$, $sn-1-C_{18:1{\omega}9}$, $sn-2-C_{18:3\;9c,11t,13t}$, $sn-3-C_{18:3\;9c,11t,13t}$ and $sn-1-C_{16;0}$, $sn-2-C_{18:3\;9c,11t,13t}$, $sn-3-C_{18:3\;9c,11t,13t}$ are the main stereoisomers for the species of $(C_{18:2{\omega}6})(C_{18:3\;9c,11t,13t})_2$, $(C_{18:1{\omega}9})(C_{18:3\;9c,11t,13t})_{2}$ and $(C_{16:0})(C_{18:3\;9c,11t,13t})$, respectively.

The Tire Damage Classification by Pulse Interval Time Density Function of Ultrasonic Wave Envelope on Driving (주행 중 타이어 손상에 의해 발생하는 초음파 포락선 신호의 펄스 간격 시간밀도함수에 의한 손상 분별)

  • Shin, Seong-Geun;Kang, Dae-Soo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.11 no.3
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    • pp.41-46
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    • 2011
  • The tire damage classification method is researched by periodicity detection of ultrasonic envelope signals to occur at the driving vehicle tire. Because periodic signals is generated by rotations of the damaged tire, it should convert to pulse for using the density function. After time intervals of pulses are represented by the density function, the dominant periodicity is detected. The threshold to make a pulse is calculated by moving average of envelope signals. The result of time density function in case of one damage material, the first peak's time is equals to tire's rotation period, 162ms and 102ms, about the speed of 50km/h and 80km/h. In case of more than one damage material, the sum of each peak's time is equals to tire's rotation period about the speed.

Total Work Changes at Different Angular Velocities during Isokinetic Exercise (등속성 운동시 각속도에 따른 총 일량(total work)의 변화)

  • Kim, Doe-Hee;Park, Young-Seogk;Yoon, Zang-Whon;Kim, Jong-Man
    • Physical Therapy Korea
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    • v.2 no.1
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    • pp.51-61
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    • 1995
  • In general, research in isokinetic exercise has focussed on studies of peak torque. However, peak torque is not always sufficient to assess the real amount of motion or to determine endurance. In this study, the subjects were 54 healthy students who performed continuous maximal isokinetic knee flexion and extension until their total work per time reached 50% of their maximal total work. Isokinetic curves were then plotted. Total work sums, exercise durations in seconds, and the numbers of repetitions were compared with reference to subject gender, angular velocity and muscle group. The relationship between total work sum, duration and number of repetition and thigh circumference plus leg length was computed. In addition, the characteristics of total work per second and total work per time were calculated. Results showed the total work sums differed greatly from muscle group to muscle group and with different angular velocities. The duration in seconds and the numbers of repetition differed only at higher angular velocity. Males achieved higher levels in every category except for some duration in seconds and some numbers of repetitions. Thigh circumference and leg length were deciding fators in every case, but duration in seconds and number of repetitions were not. These results suggest that measures of endurance should be included along with measures of total work when isokinetic studies are done. Measures of endurance in seconds are more accurate when isokinetic exercise is performed at lower angular velocities and numbers of repetitions at higher angular velocities.

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The Role of PPV and PVS in Controlled Blasting (제어발파의 설계 및 관리 과정에서의 PPV와 PVS의 역할)

  • Choi, Byung-Hee;Ryu, Chang-Ha;Hwang, Hyun-Joo;Choi, Yong-Kun;Ahn, Myung-Seog
    • Explosives and Blasting
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    • v.26 no.2
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    • pp.1-10
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    • 2008
  • The safe level for residential structures has usually been prescribed as just 'particle velocity' in various specifications in Korea. It implies that there is a possibility of interpreting the 'particle velocity' as the PPV (Peak Particle Velocity), PVS (Peak Vector Sum), or something else, depending on the interpreter. As a result, there have always been some difficulties in both designing a controlled blasting and controling the blast-induced ground vibrations. This paper is intended to show what the role of the safe level criteria such as PPV or PVS is, and also how we should use the concept of the scaled distance equation in a controlled blast design. The paper also emphasizes the importance of the allowable level for various residential structures and its uses in each stage of the controlled blast design.

An Unambiguous Correlation Function to Improve Tracking Performance for Binary Offset Carrier Signals (이진 옵셋 반송파 신호 추적 성능 향상을 위한 비모호 상관함수)

  • Woo, Sunghyuk;Chae, Keunhong;Lee, Seong Ro;Yoon, Seokho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.7
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    • pp.1433-1440
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    • 2015
  • In this paper, we propose an unambiguous correlation function to improve tracking performance for binary offset carrier (BOC) signals. Specifically, we divide a BOC sub-carrier into multiple rectangular pulses, and analyze that the BOC autocorrelation function is made up of the sum of several partial correlation functions. Then, we obtain two sub-correlation functions by combining two partial correlation functions and propose a novel unambiguous correlation function with no side-peak which can be regulated its width based on the combination of the sub-correlation functions and partial correlation functions. From numerical results, it is confirmed that the proposed correlation function provides a tracking performance improvement over the conventional correlation functions in terms of the tracking error standard deviation.

A New Selected Mapping Scheme without Side Information Using Cross-Correlation (상호 상관을 이용한 부가정보가 필요 없는 Selected Mapping 수신방법 제안)

  • Lee, Jong-keun;Chang, Dae-ig
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.42 no.4
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    • pp.739-746
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    • 2017
  • Orthogonal frequency division multiplexing(OFDM) systems have many advantages. However, OFDM systems are much affected by a nonlinear distortion because those systems have a high peak to average power ratio(PAPR) value. A selected mapping technology was suggested to reduce a PAPR value. The technology does not have data loss but receivers need side information to know modified phase sequence. Therefore, side information causes decreased a transmission efficiency. In this paper, we suggest a blind SLM receiver using a cross correlation technology. This receiver does not require side information. The proposed blind SLM receiver calculates sums of cross-correlation between transmitted pilot signals multiplied by each phase sequence and received pilot signals. So, this receiver detects side information which has a maximum sum cross-correlation value. We compared our proposed SLM receiver to a conventional blind SLM receiver through bit error rate(BER) and side information error rate(SIER) performances. Simulation results show that the proposed SLM receiver has improved BER and SIER performances than the conventional SLM receiver.

A Motion Vector Re-Estimation Algorithm for Image Downscaling in Discrete Cosine Transform Domain (이산여현변환 공간에서의 영상 축소를 위한 움직임 벡터 재추정)

  • Kim, Woong-Hee;Oh, Seung-Kyun;Park, Hyun-Wook
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.39 no.5
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    • pp.494-503
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    • 2002
  • A motion vector re-estimation algorithm for image downscaling in discrete consine transform domain is presented. Kernel functions are difined using SAD (Aum of Absolute Difference) and edge information of a macroblock. The proposed method uses these kernel functions to re-estimate a new motion vector of the downscaled image. The motion vectors from the incoming bitstream of transcoder are reused to reduce computation burden of the block-matching motion estimation, and we also reuse the given motion vectors. Several experiments in this paper show that the computation efficiency and the PSNR (Peak Signal to Noise Ratio) and better than the previous methods.

Characteristic of the pulse wave in hypertension using pulse analyzer with array piezoresistive sensor (어레이 압저항 센서 장착 맥진기의 고혈압 맥파 특성)

  • Choi, Yong-Seok;Kim, Kyung-Yo;Hwang, Seung-Yeon;Kim, Jong-Yeol;Lee, Si-Woo;Kim, Hyun-Hee;Joo, Jong-Cheon
    • Korean Journal of Acupuncture
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    • v.24 no.3
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    • pp.105-116
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    • 2007
  • Objectives : This study was performed to determine whether a pulse analyzer using array piezoresistive sensor was useful to characterize the variables of pulse wave of hypertentive patients (HT) , compared with those of healthy subjects. Methods : One hundred twenty two subjects participated in this study. Sixty nine subjects had hypertension and fifty three subjects had no specific history or disease associated with hypertension. We used automatic pulse analyzer with array piezoreslstive sensor. Results : Calibrated in Chon, no specific differences was between HT group and the healthy group. Calibrated in Gwan. sum of pulse pressure (SPP) of HT group was higher than that of the healthy group. Calibrated in Cheek, mean of height of main peak (Mm) and height of main peak (h1) of HT group were higher than those of the healthy group. Conclusions : Pulse analyzer was useful to determine the risk degree or development possibility of hypertension.

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