• The Journal of the Acoustical Society of Korea
• /
• v.38 no.3
• /
• pp.308-313
• /
• 2019

Parkinson's disease, one of the three major diseases in old age, has more than 70 % of patients with speech disorders, and recently, diagnostic methods of Parkinson's disease through speech signals have been devised. In this paper, we propose a method of diagnosis of Parkinson's disease based on deep residual gated recurrent neural network using speech features. In the proposed method, the speech features for diagnosing Parkinson's disease are selected and applied to the deep residual gated recurrent neural network to classify Parkinson's disease patients. The proposed deep residual gated recurrent neural network, an algorithm combining residual learning with deep gated recurrent neural network, has a higher recognition rate than the traditional method in Parkinson's disease diagnosis.

• Korean Journal of Psychosomatic Medicine
• /
• v.11 no.1
• /
• pp.25-35
• /
• 2003

Objectives: The aim of this study was to investigate 1) the prevalence of depressive symptoms, 2) the severity of depressive symptoms, 3) the correlation of depressive symptoms with clinical variables, and 4) factors that contribute to depressive symptoms in patients with Parkinson's disease. Methods: One hundred eighteen patients with Parkinson's disease referred from the Parkinson's Disease Clinic of Dong-A University Hospital, Busan, Korea, completed a self-administered questionnaire package, which included basic demographic data, the Beck Depression Inventory, the Parkinson's disease quality of life questionnaire, the Symptom Checklist-90-Revision(SCL-90-R), and the Spielberger's State-Trait Anxiety Inventory. In addition, a structured interview and a complete neurological examination, including the Hoehn and Yahr stage, the motor part of the Unified Parkinson's Disease Rating Scale(some selected scales of UPDRS part III), the Schwab and England Activities of Daily Living scale(ADL), and the Korean version of Mini-Mental State Examination were performed. Results: 1) Based on BDI score, subjects were divided into four groups:severely(40.7%), moderately(13.6%) and mildly(12.7%) depressive and non-depressive(33.1%). 2) The severity of depressive symptom in Parkinson's disease was positively correlated with Hoehn and Yahr(H & Y) stage(r=0.34, p<0.0001), the severity of motor symptom(r=0.35, p<0.0001), and trait anxiety inventory(r=0.33, p<0.001). On the other hand, the severity of depressive symptom was negatively correlated with educational level(r=-0.34, p<0.001), ADL(r=-0.37, p<0.0001) and Parkinson's disease quality of life (PDQL)(r=-0.69, p<0.0001). Among several clinical variables, the PDQL was the most influential factor predicting whether the depressive symptom was present or not. Conclusion: This study suggests that depressive symptom is very prevalent among patients with Parkinson's disease. Data from this study indicate that medical staffs who take care of patients with Parkinson's disease should pay attention to finding and treating depressive symptom among their patients. With appropriate psychiatric intervention, patient's depressive symptom can be minimized or alleviated and thus, the quality of life in these patients is likely enhanced.

• The Journal of the Korea Contents Association
• /
• v.16 no.1
• /
• pp.676-687
• /
• 2016

The purpose of this study was to examine the relation of motor function, depression, and fear of falling, and to identify factors influencing fear of falling in patients with Parkinson's disease in the community. The participants were 180 patients with Parkinson's disease who were selected by convenience sampling. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient and multiple linear regression. There was a significant difference in fear of falling according to gender, occupation, walking assistance device, number of falls, Parkinson's disease stage, duration of illness, antihypertensive drug, motor function, and depression. Fear of falling showed significant positive correlations with motor function, and depression. Depression, number of falls, Parkinson's disease stage, gender, antihypertensive drug, and motor function were significant predictors influencing fear of falling in patients with Parkinson's disease, and these variables accounted for 36.0% of the variance. Depression of the influencing factors was the strongest factor. The results of this study suggest that a variety of intervention strategies for preventing or mitigating depression with systematic nursing assessment of the influencing factors on fear of falling are needed to prevent fear of falling in patients with Parkinson's disease.

• Journal of TMJ Balancing Medicine
• /
• v.11 no.1
• /
• pp.12-19
• /
• 2021

There are many studies that show the association between Parkinson's disease and temporomandibular joint disorder. However, no clinical studies have yet been reported that TMJ Banlancing Therapy (TBT) can treat Parkinson's disease. In this study, the applicability of TBT for the treatment of Parkinson's disease was investigated by reviewing several studies on the factors related to Parkinson's disease and temporomandibular joint disorder and clinical studies of patients with Parkinson's disease using conventional oral appliances and exercises. In summary, it is considered that TBT has a high potential for use in the treatment of Parkinson's disease, but it is thought that prospective clinical research is needed in the future to establish objective evidence related to this.

• Speech Sciences
• /
• v.12 no.2
• /
• pp.59-72
• /
• 2005

The purpose of this study was to investigate the effects of rhythm therapy program on MPT(Maximum Phonation Time) and acoustic parameters in patients with Parkinson's disease. The therapy program utilized 5 Korean traditional rhythms: jinngyang, jungmori, jungjungmori, jajinmori, and semachi. The therapy consisted of counseling regarding vocal hygiene and actual therapy procedures. Six subjects with Parkinson's disease participated in the study; 3 subjects in experimental group and the other 3 subjects in control group. The pre- and post- acoustic analyses were performed in both groups. The results of this study were as follows; 1) MPT was significantly increased in the experimental group, 2) mono-pitch was significantly improved in the experimental group, 3) mono-loudness was significantly improved in the experimental group, and finally, HNR was significantly increased in the experimental group compared to the control group.

• Journal of muscle and joint health
• /
• v.19 no.3
• /
• pp.350-361
• /
• 2012

Purpose: The purpose of this study is to explore the level of bone mineral densities of the femur neck and to identify factors affecting bone mineral density of the femur in Parkinson's disease (PD) patients. Methods: Participants were 121 PD patients visiting the outpatient clinic of D University Hospital in B City. Bone mineral density was measured at the femur neck by using a dual-energy x-ray absorptiometry. The serum vitamin D level, the amounts of milk intake, caffeine intake, cigaret smoking, and alcohol consumption, and the number of steps taken daily were measured. Past and present disease history, the medication history, and duration of the disease were also collected. The level of disability was obtained by neurologists using the Hoehn and Yahr stage and the Unified Parkinson's Disease Rating Scale. Results: Among PD patients, 57% had osteopenia and 15.7% had osteoporosis. The bone mineral density of the femur was associated with weight, serum vitamin D level, age, and working status. Conclusion: The identification of weight and serum vitamin D level as important predictive factors emphasizes the importance of balanced nutrition for PD patients.

• PNF and Movement
• /
• v.15 no.3
• /
• pp.333-341
• /
• 2017

Purpose: This study was to explore the effects of trunk exercise using PNF combined with treadmill training on balance and walking ability in patients with Parkinson's disease. Methods: This study included 16 patients with Parkinson's disease. Participants were randomly assigned to 2 groups: an experimental group (n=8) and a control group (n=8). All participants underwent treadmill training for 30 minutes. In addition, the experimental group (trunk exercise using PNF) and control group (conventional training) participated in a 30-minute exercise program. Both groups performed the training 5 times per week for 4 weeks. Disease severity (determined using the unified Parkinson's disease rating scale motor subscale, UPDRS-3), balance (determined using the Berg balance scale, BBS), walking speed (determined using the 10-meter walking test, 10MWT), and walking endurance (determined using the 6-minute walking test, 6MWT) were measured at baseline and after 4 weeks. Results: Pre- to post-intervention improvement was noted on all outcome measures for both groups (p<0.05). Post-intervention, there was a significant improvement in the experimental group as compared to the control group for the following measured outcomes (p<0.05): UPDRS-3 (p=0.03; 95% CI, -5.52 to -0.24), BBS (p=0.04; 95% CI, 0.59 to 6.45), 10MWT (p=0.01; 95% CI, -2.19 to -0.42), and 6MWT (p=0.04; 95% CI, 1.81 to 96.72) Conclusion: The results of this study revealed that trunk exercise using PNF plus treadmill training improves balance and walking ability as compared to conventional training plus treadmill training in patients with Parkinson's disease.

• The Journal of Korean Physical Therapy
• /
• v.31 no.2
• /
• pp.122-128
• /
• 2019

Purpose: This study examined the effects of sagittal spinopelvic alignment on the clinical parameters, motor symptoms, and respiratory function in patients with mild to moderate Parkinson's disease (PD). Methods: This study was a prospective assessment of treated patients (n=28, Hoehn and Yahr (H&Y) stage 2-3) in a PD center. Twenty-eight subjects ($68.5{\pm}5.7yrs$) participated in this study. The clinical and demographic parameters, including age, sex, symptoms duration, treatment duration, and H&Y stage, were collected. Kinematic analysis was conducted in the upright standing posture with a motion capture system. A pulmonary function test (PFT) was performed in the sitting position using a spirometer. The motor symptoms were assessed on part III of the movement disorder society sponsored version of the unified Parkinson's disease rating scale (MDS-UPDRS). SPSS 18.0 was used to analyze the collected data. Results: The exceeding 12 degrees group of the lower trunk showed significantly higher on the clinical parameters than the below 12 degrees group. In addition, the exceeding 12 degrees group of the lower trunk showed a significantly lower forced expiratory volume at one second (FEV1) / forced vital capacity (FVC) (%) and 25-75% forced mid-expiratory flow (FEF) (L/s) than in the below group. On the other hand, there was no difference in the upper trunk and the cervical pelvis between the groups. Conclusion: These findings suggest that the sagittal balance in the lower trunk is related to the clinical parameters and respiratory function, but not the motor symptoms in patients with mild to moderate PD.

• Journal of Sasang Constitutional Medicine
• /
• v.24 no.3
• /
• pp.104-113
• /
• 2012

Objectives This study is about a "Taeumin" parkinson's disease patient with bradykinesia, tremor, weakness and dysautonomia etc. In this case, we evaluated the effect of Yuldahanso-tang gagam for parkinson's disease. Methods This patient was treated by Sasang constitutional herbal medication based on "Donguisusebowon". Acupuncture and west medications were used together. We evaluated the clinical progress through two methods, DITI(Digital Infrared Thermal Imaging) and VAS(Visual Analogue Scale). Results During 11months treatment, chief complaints and symptoms of this patient were improved. Conclusions This study shows that Yuldahanso-tang gagam is an effective treatment for "Taeumin" parkinson's disease patients.

• PNF and Movement
• /
• v.17 no.3
• /
• pp.339-351
• /
• 2019

Purpose: This study identified the effects of dual-task gait training on balance, gait function, and activity of daily living in patients with Parkinson's disease. Methods: This study used a single-subject design. Two patients with Parkinson's disease participated in this study. Dual-task gait training was performed 1 hour per day 8 times during intervention phase. The subjects were measured 8 times in the baseline phase, 8 times in the intervention phase, and 8 times in the follow-up phase. The outcome measurements included a timed up and go test (TUG), a Berg balance scale (BBS), a 10 meter walk test (10MWT), a 6 minute walk test (6MWT), a dynamic gait index (DGI) and a Korean modified Barthel index (K-MBI). Results: When compared to the average of the baseline process, the data collected during the intervention period showed that the TUG and 10MWT results improved and the tendency line was above the baseline. In addition, BBS, 6MWT, DGI, and K-MBI values for both patients increased remarkably after the training. Conclusion: The results of this study revealed that dual-task gait training may be helpful to improve balance, walking function, and activity of daily living for patients with Parkinson's disease. Further studies need to confirm our findings.