• Title/Summary/Keyword: Pathological Symptoms

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A Successfully Treated Case of Gorham-Stout Syndrome with Sternal Involvement

  • Kim, Bong Jun;Kim, Tae Hoon;Kim, Do Jung;Noh, Dongsub;Haam, Seok Jin;Lee, Sungsoo
    • Journal of Chest Surgery
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    • v.48 no.1
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    • pp.90-94
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    • 2015
  • Gorham-Stout Syndrome (GSS) is a rare disease characterized by localized bone resorption. Any part of the skeleton may be affected; therefore, symptoms can vary depending on the site involved. Pathological analysis reveals lymphovascular proliferation and osteolysis in the affected lesion, but the etiology of the disease is poorly understood. When GSS occurs in the chest, chylothorax or respiratory failure may occur. Thus far, a standard treatment for GSS has not been established, and the prognosis remains unknown. The following case report describes a successfully treated case of GSS in a 16-year-old boy with an affected sternum and ribs.

Text-Mining of Online Discourse to Characterize the Nature of Pain in Low Back Pain

  • Ryu, Young Uk
    • Journal of the Korean Society of Physical Medicine
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    • v.14 no.3
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    • pp.55-62
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    • 2019
  • PURPOSE: Text-mining has been shown to be useful for understanding the clinical characteristics and patients' concerns regarding a specific disease. Low back pain (LBP) is the most common disease in modern society and has a wide variety of causes and symptoms. On the other hand, it is difficult to understand the clinical characteristics and the needs as well as demands of patients with LBP because of the various clinical characteristics. This study examined online texts on LBP to determine of text-mining can help better understand general characteristics of LBP and its specific elements. METHODS: Online data from www.spine-health.com were used for text-mining. Keyword frequency analysis was performed first on the complete text of postings (full-text analysis). Only the sentences containing the highest frequency word, pain, were selected. Next, texts including the sentences were used to re-analyze the keyword frequency (pain-text analysis). RESULTS: Keyword frequency analysis showed that pain is of utmost concern. Full-text analysis was dominated by structural, pathological, and therapeutic words, whereas pain-text analysis was related mainly to the location and quality of the pain. CONCLUSION: The present study indicated that text-mining for a specific element (keyword) of a particular disease could enhance the understanding of the specific aspect of the disease. This suggests that a consideration of the text source is required when interpreting the results. Clinically, the present results suggest that clinicians pay more attention to the pain a patient is experiencing, and provide information based on medical knowledge.

Arthroscopic Excision of Medial Knee Plica: A Meta-Analysis of Outcomes

  • Gerrard, Adam Daniel;Charalambous, Charalambos P.
    • Knee surgery & related research
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    • v.30 no.4
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    • pp.356-363
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    • 2018
  • Purpose: A meta-analysis was performed to assess the outcomes following surgical intervention for medial knee plica. Materials and Methods: A literature search of Medline, EMBASE, CINAHL and Cochrane CENTRAL was performed using relevant key words. The primary outcome was patient-reported postoperative scores of "good" and "excellent". Meta-analyses were performed using a random effects model. Results: The literature search identified 731 articles. After removing duplicates and those not meeting the inclusion criteria, 12 articles reporting on a total of 643 knees were included for analysis, and of these, 7 articles including 235 knees were used for meta-analysis. The overall rate of good and excellent outcomes following surgery was estimated at 84.2% (95% confidence interval [CI], 72.8-91.4). In those cases that had non-surgical therapy prior to surgery, the rate of good and excellent outcomes of surgery was estimated at 76.1% (95% CI, 60.1-87). Conclusions: Arthroscopic surgical management of symptomatic medial knee plica results in favourable outcomes. Our results suggest that arthroscopic surgical excision should be considered as a treatment modality in patients with pathological medial plica disease of the knee either as a first-line treatment or when symptoms have not responded to non-surgical interventions. Level of Evidence: IV.

Qualitative Approach to Maintaining the Effect of Fashion Therapy (패션테라피 효과 유지에 대한 질적 접근)

  • Lee, Sae Eun;Lee, Yuri
    • Journal of the Korean Society of Clothing and Textiles
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    • v.43 no.3
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    • pp.311-326
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    • 2019
  • Previous studies on the effect of fashion therapy have been conducted with psychiatric patients; however, this study explores the effects in fashion therapy for women with non-pathological problems. Previous studies did show if the effect of fashion therapy could be maintained continuously; therefore, we intend to examine the existence of the long-term effects of fashion therapy in an empirical manner and provide implications for social and public interest. This study used a qualitative approach to investigate the effects of fashion therapy with the following results. Low self-esteem, negative emotions, and rigid thinking symptoms appeared by numerous stress factors, and various changes were made through fashion therapy. Emotional changes such as positive emotions and feeling of achievement, and psychological changes including self-concept formation, change of sight and self-esteem improvement appeared. Sociological and behavioral changes were also identified. We found the maintained and long term effects of fashion therapy; therefore, study provides academic implications to reconsider the social value of fashion.

Intestinal Lymphoma in a Halla Horse

  • Jeong, Hyohoon;Lee, Seyoung;Park, Kyung-won;Lee, Eun-bee;Kim, Jae-Hoon;Jung, Ji-Youl;Seo, Jong-pil
    • Journal of Veterinary Clinics
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    • v.39 no.3
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    • pp.138-143
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    • 2022
  • A 21-year-old female Halla Horse weighing 248 kg was referred to the Jeju National University Equine Hospital with the chief complaint of anorexia accompanied by general weakness and depression for the previous three days suspected to be related to colic. Extensive diagnostic tests were performed for the following six days, including complete blood count (CBC), serum chemistry, gastroscopy, x-rays, and ultrasound imaging. The signalment, history, symptoms, and test results strongly suggested a chronic intestinal inflammatory disease with or without an alimentary tumor; hence, an exploratory laparotomy was performed. Almost the entire small intestine wall was severely thickened with diffuse ecchymosis on the serosa and protruded nodules on the mucosa. A presumptive diagnosis of an intestinal tumor was made, and the patient was euthanized, considering the patient's welfare with poor prognosis and low expectancy. A massive part of the small intestine was collected and submitted for macroscopic and microscopic pathology evaluations. The pathologic examination, including immunohistochemistry (IHC), indicated equine intestinal lymphoma showing strong positivity for T cell marker. This report describes the clinical signs, diagnosis and pathological features of intestinal lymphoma in a Halla Horse in detail.

Correlation Analysis of Pressure Pain Threshold and Muscle Thickness in Individuals with Non-Specific Low Back Pain

  • Kim, Hyun-Joong;Moon, Seoyoung
    • Physical Therapy Rehabilitation Science
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    • v.11 no.3
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    • pp.329-334
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    • 2022
  • Objective: Low back pain (LBP) is a symptom that accounts for a large proportion of musculoskeletal pain. Among them, non-specific LBP (NSLBP) means that the pathological cause is unknown, and belongs to the most common LBP. Studies on the mechanism of muscle control in LBP are insufficient, and quantitative studies are needed. Design: Observational cross-sectional study design Methods: A Thirty participants with NSLBP symptoms were enrolled, and their pressure pain thresholds (PPT) and muscle and fat thickness were measured. Participants measured the paraspinal muscles (PM) of the thoracic and lumbar spine and medial hamstring (semitendinosus) on the dominant and non-dominant sides in the prone position. Results: Among the variables that were significant in the correlation analysis, PM of the thoracic and lumbar spine showed a significant relationship in the PPT ([thoracic spine PM]=1.141+0.912 [lumbar spine PM]). Also, there was a significant relationship between the lumbar spine PM in the PPT and the thoracic spine PM in the muscle thickness ([lumbar spine PM of PPT]=4.057+0.117 [thoracic spine PM of muscle thickness]) Conclusions: Although there was no muscle imbalance according to the dominant and non-dominant side, there is a correlation between the pressure pain threshold and the muscle thickness between the paraspinal muscles of the thoracic spine and the lumbar spine.

A Study on the Significance of Acupuncture and Pharmacopuncture Therapy for Cold Accumulation Through a Literature Review on the Historical Development Process in Cold Accumulation Treatment

  • Jin-Ho, Jeong;Jaseung, Ku;Ji Hye, Hwang
    • Journal of Acupuncture Research
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    • v.39 no.4
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    • pp.267-274
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    • 2022
  • In order to secure clinical evidence for the treatment of cold accumulation (CA), this study reviewed and analyzed 91 records of literature and related records. To perform a classical literature search, the Oriental Medicine Classic databases and the Uibujeonrok electronic data were searched. Books on Immunopharmacopuncture (IP) were also reviewed. A common etiology for CA was attributed to the abdomen, while the detailed sites of the abdomen differed. In IP, CA had a more comprehensive list of symptoms of physiological and pathological significance. As for the treatment of CA, typically, herbal medicine was used until the end of the Korean Empire period, and moxibustion treatment on CV4, CV6, CV-12, ST36, EX-B4, and conduction exercise therapy were also reported. Since 1965, acupuncture needle-based invasive treatment such as acupuncture for CA, and IP have been described in IP theory. Consequently, the treatment of CA (as described in the IP theory), was considered to be a more advanced method of treatment compared with the existing classical treatment methods.

A case of a patient with irritable bowel syndrome diagnosed with Shanghanlun Yangmingbing Soseunggi-tang (『상한론(傷寒論)』 양명병(陽明病) 소승기탕(小承氣湯)으로 진단된 과민 대장 증후군 환자 1례)

  • Jae-young Choi;Soong-in Lee;Mi-hyun Lee;Sung-jun Lee
    • 대한상한금궤의학회지
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    • v.14 no.1
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    • pp.81-93
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    • 2022
  • Objective : This study reports on the case of a patient with irritable bowel syndrome (IBS) diagnosed by the Shanghanlun disease pattern identification diagnostic system (DPIDS). We tried to verify the therapeutic effects of Soseunggi-tang (SSGT) administration and pathological character. Methods : The patient was administered SSGT for 31 days. We observed the progression of symptoms, patient compliance, and the presence of side effects. The progression of IBS was evaluated based the on Gastrointestinal Symptom Rating Scale (GSRS). Abdominal pain, flatus, visual findings, and patient statements were also assessed. Results : According to the DPIDS, the patient was diagnosed with Yangmingbing (陽明病). As a result, his GSRS score dropped from 15 to 5, the visual analog scale (VAS) score for abdominal pain lowered from 9 to 4, and the VAS score for flatus decreased from 8 to 4. The stool type changed from diarrhea to a loose stool form. Conclusions : SSGT showed therapeutic effects on the patient diagnosed with IBS and Yangmingbing.

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RENE LAENNEC'S SYNDROME-BASED CLINICAL REASONING

  • Berezutskyi Volodymyr
    • CELLMED
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    • v.14 no.2
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    • pp.4.1-4.4
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    • 2024
  • The development of clinical reasoning, which is the basis of medical education, is of great importance in medical universities. One of the founders of modern structural clinical reasoning, based on the knowledge of pathological physiology, is the inventor of the stethoscope Rene Laennec (1781-1826). He described the pioneering experience of clinical reasoning in the pages of his treatise A Treatise on the Diseases of the Chest and on Mediate Auscultation, which is of lasting value, since every rookie physicians in his professional development goes through the path of Laennec. Laennec's practice is of great importance for novice physicians since Laennec's treatise contains a diagnostic analysis of the most common clinical cases. Each such analysis demonstrates the algorithm of clinical reasoning. The purpose of this study was to analyze the approaches of clinical reasoning by René Laennec, which made it possible to identify two basic principles. Laennec's diagnostic reasoning involved two principles: pathogenetic analysis of clinical manifestations and a syndrome-based approach to differential diagnosis. These principles help distinguish between diseases with similar symptoms and physical findings are used to demonstrate the practical application of syndrome-based differential diagnosis. These principles can be easily mastered by understanding the pathogenesis of clinical manifestations. Thanks to the pathogenetic basis, the principles of clinical reasoning of Rene Laennec are universal and applicable to the analysis of any signs of the disease: not only physical but also laboratory and instrumental.

The Nevus Lipomatosus Superficialis of Face: A Case Report and Literature Review

  • Jae-Won Yang;Mi-Ok Park
    • Archives of Plastic Surgery
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    • v.51 no.2
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    • pp.196-201
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    • 2024
  • Nevus lipomatosus superficialis (NLS) is a hamartoma of adipose tissue, rarely reported in the past 100 years. We treated one case, and we conducted a systematic review of the literature. A 41-year-old man presented with a cutaneous multinodular lesion in the posterior region near the right auricle. The lesion was excised and examined histopathologically. To review the literature, we searched PubMed with the keyword "NLS." The search was limited to articles written in English and whose full text was available. We analyzed the following data: year of report, nation of corresponding author, sex of patient, age at onset, duration of disease, location of lesion, type of lesion, associated symptoms, pathological findings, and treatment. Of 158 relevant articles in PubMed, 112 fulfilled our inclusion criteria; these referred to a total of 149 cases (cases with insufficient clinical information were excluded). In rare cases, the diagnosis of NLS was confirmed when the lesion coexisted with sebaceous trichofolliculoma and Demodex infestation. Clinical awareness for NLS has increased recently. NLS is an indolent and asymptomatic benign neoplasm that may exhibit malignant behavior in terms of huge lesion size and specific anatomical location. Early detection and curative treatment should be promoted.