• Title/Summary/Keyword: Patent Medicine

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Review on the Stimulating Technologies of Acupuncture Points in the Patents (특허분석을 통한 경혈 자극 기술에 대한 고찰)

  • Park, Chin-Su;Hwang, Yo-Sun;Koo, Sung-Tae
    • Korean Journal of Acupuncture
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    • v.28 no.3
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    • pp.113-126
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    • 2011
  • Objectives : We have examined and analyzed patents regarding acupuncture point stimulating methods in order to understand the stimulation technology and research trends of acupuncture points. Methods : We searched and analyzed the total of 135 on-line DB based patents under time limit of Dec, 2010. Results : According to the analyzed results, non-invasive method is used more than invasive method. Electric stimulation is used more than any other method, such as magnetic, ionic, laser, light, ultrasonic, water, Far IR and thermal stimulation. There are numbers of cases such as rejected during screening procedure, waived before the screening, of failed to renew its registrational status which outnumber those patents registered and maintained. Conclusions : These data suggest that we need to move away from using one side method such as non-invasive and electrical method. Thus follow-up service is recommended.

A Clinical Study of Patent Ductus Arteriosus (동맥관개존증의 임상적 고찰)

  • Bang, Jong-Gyeong;Kim, Gyu-Tae
    • Journal of Chest Surgery
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    • v.20 no.2
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    • pp.309-316
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    • 1987
  • Since the first report of successful ligation of patent ductus arteriosus in 1939, it`s surgical intervention has become a routine and relatively safe procedure. During the past ten years from Aug. 1975 to Aug. 1985, 107 cases were operated on for a patent ductus arteriosus at the Department of thoracic and Cardiovascular Surgery, School of Medicine, Kyungpook National University. Clinical analysis of these cases was performed. Mean age at operation was 9.4 years, ranging from 20 months to 32 years. Sex ratio of female to male was 1.8;1. Most common symptoms were frequent respiratory infection, exertional dyspnea, and palpitation. Diagnosis was made by auscultation, 2 dimensional echocardiography, cardiac catheterization, and cineangiocardiography. A moderate to severe pulmonary hypertension was found in 42 cases [49.4%] in cardiac catheterization. Operative methods were multiple ligation of paten`. ductus arteriosus with or without Dacron or Teflon wrapping in 72 cases [68%], and division and suture in 34 cases [32%]. There were three operative deaths [2.8%]. The causes of death were hemorrhage from tearing of aorta, low cardiac output, and arrhythmia. All of these cases had moderate degree of pulmonary hypertension.

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Practice for preterm patent ductus arteriosus; focusing on the hemodynamic significance and the impact on the neonatal outcomes

  • Lee, Jin A
    • Clinical and Experimental Pediatrics
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    • v.62 no.7
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    • pp.245-251
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    • 2019
  • Hemodynamically significant preterm patent ductus arteriosus (PDA) affects mortality; comorbidities such as necrotizing enterocolitis, intraventricular hemorrhage, and bronchopulmonary dysplasia; and adverse long-term neurodevelopmental outcomes in preterm infants, particularly in very low birth weight infants. However, recent studies have indicated that there is no consensus on the causal relationship between PDA and neonatal outcomes, the benefit of PDA treatment, the factors guiding the need for treatment, and optimal treatment strategies. Such uncertainty has resulted in wide variations in practice for treating preterm PDA between units, regions, and nations. Nowadays, there has been a paradigm shift to more conservative treatment for preterm PDA, and suggestions regarding selective management of preterm PDA considering risk factors and hemodynamic significance are increasing. Neonatologist-performed echocardiography and advances in modalities to assess hemodynamic significance such as biologic markers and near-infrared spectroscopy also help improve the efficacy of selective treatment of preterm PDA.

Surgical Closure of the Patent Ductus Arteriosus in Premature Infants by Axillary Minithoracotomy (액와 소개흉술에 의한 미숙아 동맥관 개존증의 외과적 치료)

  • Cho, Jung-Soo;Yoon, Yong-Han;Kim, Joung-Taek;Kim, Kwang-Ho;Hong, Yung-Jin;Jun, Yong-Hoon;Shinn, Helen Ki;Baek, Wan-Ki
    • Journal of Chest Surgery
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    • v.40 no.12
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    • pp.837-842
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    • 2007
  • Background: Closure of the ductus arteriosus is often delayed in premature infants, which creates a hemodynamically significant left to right shunt that exerts an adverse effect on the normal development and growth of these babies. We reviewed out experience on surgical closure of patent ductus arteriosus via axillary minithoracotomy in premature infants. Material and Method: From April 2002 to October 2006, 20 premature infants whose gestation was under 37 weeks underwent surgical closure of patent ductus arteriosus as a result of complications or contra-indications for the use of indomethacin. Their mean gestational age was 28.8+3.4 weeks, ranging from 25+3 to 34+6 weeks, and the average age at operation was $15.6{\pm}6.3$ days. The mean body weight at operation was $1,174{\pm}416\;g$, ranging from 680 to 2,100g; 16 infants were under 1,500 and 9 infants were under 1,000 g. The procedures were performed in the newborn intensive care unit via $2{\sim}3\;cm$ long axillary minithoracotomy with the infant in the lateral position with left arm abduction. The mean size of the patent ductus arteriosus was $3.8{\pm}0.3\;mm$. For the most part, the ductus was closed with clips; 2 infants in whom the ductus was ruptured while dissection was being performed underwent ductal division. Result: Ten of twelve infants who had been ventilator dependent preoperatively could be successfully weaned from the ventilator at a mean duration of 9.7 days after the operation. There was no procedure-related complication or death. Two infants eventually died of the conditions not related to the operation; one from sepsis at postoperative 131 days and the other from pneumonia at postoperative 41 days, respectively. Conclusion: Surgical closure of the patent ductus arteriosus improved the hemodynamic instability and so promoted the successful growth and normal development of premature infants. Considering the low surgical risk along with the reduced invasiveness, early and aggressive surgical intervention is highly recommended.

Cor Triatriatum Dexter Complicated with Pulmonic Stenosis and Patent Foramen Ovale in A Pitbull Terrier Puppy (핏불테리어종 자견에서 폐동맥 협착과 난원공 개존증이 합병된우측 삼중심방증)

  • Choi, Ran;Lee, Dong-Guk;Choi, Hyun-Seok;Hyun, Changbaig
    • Journal of Veterinary Clinics
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    • v.31 no.2
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    • pp.112-116
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    • 2014
  • A 2-month-old intact male Pitbull terrier (weighing 1.01 kg) were referred with primary complaints of severe abdominal distension, exercise intolerance, retarded growth, yellow nasal discharge and anorexia. Diagnostic imaging studies found enlarged right atrium partitioned by abnormal membrane, severe pulmonic systolic jets (5.66 m/s of peak velocity) and right-to-left blood shunt at the inter-atrial septum. Based on clinical and diagnostic findings, the case was diagnosed as cor triatriatum dexter complicated with severe pulmonic stenosis and right-to-left shunted patent foramen ovale. Either surgical or interventional therapy has not been attempted, because of unstable patient's condition. Using blood transfusion, oxygen supply and cardiac medications (i.e., sildenafil, spironolactone, enalapril), the dog was recovered.

Establishment of a development direction for smart aquaculture technology through patent analysis and a demand survey of experts and fishermen (특허 현황 분석과 전문가 및 어업인 수요 조사를 통한 스마트 수산 양식 기술 개발 방향 설정)

  • KWON, Inyeong;CEONG, Hyithaek;LEE, Jihoon;KIM, Eun-Sik;KIM, Wi-Sik;KANG, So Young;HWANG, Min-Jin;KIM, Taeho
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.55 no.4
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    • pp.378-391
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    • 2019
  • The objective of this study is to establish a direction for smart aquaculture technology development in the Republic of Korea through patent analysis and a demand survey of experts and fishermen. The patent analysis was conducted using Wisdomain for patents in the Republic of Korea, the United States of America, Europe, Japan, and China from 2005 to 2016. This study conducted an analytic hierarchy process (AHP) survey of experts in the fields of fishery, marine, and ICT among others. Furthermore, it carried out a demand survey of 85 fishermen in Jeonnam and Jeju. The smart aquaculture technology market has moderately grown in the Republic of Korea until recently, and it is expected to expand further because of the expansion of national investment in the smart aquaculture field. The priority evaluation results for developing smart aquaculture technology show that land-based aquaculture has a higher priority than sea-based aquaculture. Of the fishermen that responded, 84% said that they need to introduce smart aquaculture technology to solve problems in the supply and demand of manpower, labor cost, and maintenance expenses. The direction of development should lie in developing biological and environment-based standard aquaculture models to spread high-tech systems and vitalize the aquaculture industry. This requires continual training of human resources in the smart aquaculture field.

Left Carotid-to-Subclavian Artery Bypass Grafting for Recurrent Angina Caused by Coronary-Subclavian Steal Syndrome

  • Kim, Min-Seok;Paeng, Jin Chul;Kim, Ki-Bong;Hwang, Ho Young
    • Journal of Chest Surgery
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    • v.46 no.1
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    • pp.84-87
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    • 2013
  • A 60-year-old man visited the outpatient clinic due to one month of recurrent exertional chest pain. Eleven years earlier he had undergone off-pump coronary artery bypass grafting using bilateral internal thoracic artery (ITA) Y-composite grafts based on the left ITA. Preoperative coronary angiography showed patent distal graft anastomoses and visualized the left ITA retrogradely. The arch aortography revealed near-total occlusion of the left subclavian artery at the level of the ostium. The patient underwent left carotid-to-subclavian artery bypass grafting using a 6 mm vascular conduit. Postoperative computed tomographic angiography revealed a patent bypass conduit between the left common carotid artery and left subclavian artery. The patient was discharged on postoperative day 4 with no symptoms or signs of myocardial ischemia.

Patent Ductus Arteriosus Occlusion with an $Amplatz^{(R)}$ Canine Duct Occluder in a Dog (개에서 $Amplatz^{(R)}$ Canine Duct Occluder를 이용한 동맥관개존증의 폐쇄 증례)

  • Kang, Min-Hee;Kim, Seung-Gon;Hahn, Tae-Yeon;Park, Hyun-Ah;Min, Sa-Hee;Park, Ji-Hwan;Kim, Tae-Woo;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.29 no.6
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    • pp.498-501
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    • 2012
  • A 10-month-old intact male Maltese dog (body weight, 1.6 kg) presented with intermittent cough and abnormal heart sounds. The dog was diagnosed with a left-to-right patent ductus arteriosus (PDA) on the basis of the results of transthoracic echocardiography, color flow Doppler examination, and angiography. Transcatheter occlusion of the PDA was performed using the $Amplatz^{(R)}$ Canine Duct Occluder (ACDO) via the femoral artery. The device was placed under fluoroscopic guidance and successfully occluded the PDA. The continuous heart murmur disappeared immediately after the correction and no residual flow was detected. The dog was discharged the following day and regularly examined for complications and safety. This is the first report demonstrating the clinical application of ACDO for the transcatheter closure of PDA via the femoral artery in a small-breed dog in Korea.

Closure of Patent Ductus Arteriosus with a Method of Double Ligation in a Dog (개에서 이중 결찰법을 통한 동맥관 개존증의 완치 예)

  • Yoon, Heo-Young;Jung, Soon-Wook;Park, Hee-Myung;Park, Chul;Jung, Man-Bok;Kim, Jun-Young;Han, Hyun-Jung;Hwang, Min;No, Byung-Guk;Park, Sang-Hyuk;Jang, Ha-Young;Park, Jung-Yoon
    • Journal of Veterinary Clinics
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    • v.21 no.1
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    • pp.72-75
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    • 2004
  • A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary leaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 UR.), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasohographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.