• Journal of Pharmaceutical Investigation
• /
• v.29 no.4
• /
• pp.343-348
• /
• 1999

The purpose of this study is to prepare the controlled release adhesive patch containing naproxen. Pressuresensitive adhesive (PSA)-type patch was fabricated by casting of polyisobutylene (PIE.) and mineral oil in toluene. Membrane-controlled release (MCR)-type patch was prepared by the attachment of the controlled release membrane on the PSAtype patch. The membrane was mainly composed of Eudragit, polyethylene glycol(PEG) and glycerin. The drug release profile and skin permeation test with various patches were evaluated in vitro. The release of naproxen from PIE-based PSAtype patch with various loading doses fitted Higuchi's diffusion equation. However, the permeation of naproxen through hairless mouse skin from PSA-type patch followed zero-order kinetics. In MCR-type patch, thickness of controlled release membrane affected on the drug release rate highly. In the composition of membrane, the release rate was decreased as the ratio of Eudragit increased. The drug release from the MCR-type patch followed zero order kinetics. The permeation of naproxen through hairless mouse skin from MCR-type patch showed lag time for the intial release period and didn't fit the zero-order kinetics

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.14 no.12
• /
• pp.1233-1238
• /
• 2003

In this paper, radially corrugated circular-type microstrip patch antenna was devised and manufactured for GPS (center frequency: 1.575 GHz). Radially corrugated circular-type microstrip patch antenna having radiational corrugation-patch contributed to add size reduction ratio by lowering the resonant frequency because the edge current also has the extended and perpendicular path. As a result, radially corrugated circular-type microstrip patch antenna has 28 % area reduction than planer circular-type patch antenna for linear polarization and 27.7 % area reduction than planer circular-type patch antenna for circular polarization. Radially corrugated circular-type microstrip patch antenna is suitable for miniaturized receive antenna for GPS which has the characteristic of gain 2.1 dBd, axiai ratio 1.3 dB, 2 dB axial bandwidth 15 MHz(0.9 %).

• Proceedings of the Korea Electromagnetic Engineering Society Conference
• /
• 2003.11a
• /
• pp.464-467
• /
• 2003

In this paper, to reduce the patch size of microstrip antenna, folded surface-type patch antenna is designed and fabricated. Size reduction could be achieved because of the downed resonant frequency by the extended current path passing along below the transformated patch surface. Comparison of the patch size at the 1.575 GHz between plane type(length 82 mm${\times}$width 90 mm) and "ㄷ"-shaped folded type is carried and comparision of frequency variation at the same patch size is carried. The result is like that the patch size was reduced than the plane type by 60 mm(73.17 %) at the same frequency. Therefore, it could be checked that "ㄷ"-shaped folded type antenna is advantageous than the plane type in size reduction.

• Journal of the Korean Society of Manufacturing Technology Engineers
• /
• v.7 no.3
• /
• pp.104-109
• /
• 1998

This document is a experimental study on fatigue life of brace mounting weld joint. A brace is used to put sub-frame together on the main frame with high strength bolts. It has low fatigue life so a patch is in need for improving a fatigue characteristics of welded joint in brace mounting This paper presents the most pertinent patch size for truck. For this, a critical stress is computed at the point of fatigue crack occurred on truck frame by finite Element Analysis. Using by this critical stress. Designers are able to determin whether fatigue crack is occurred and are able to select a pertinent patch type. And then, with a selected patch type, structural joint stiffness was estimated to compare to the conventional and other patch type or brace mounting Finally, fatigue test were performed to prove a suitability of selected prototype compare with the conventional and other patch type or brace mounting.

• YAKHAK HOEJI
• /
• v.43 no.4
• /
• pp.447-457
• /
• 1999

The purpose of this study is to prepare the adhesive type patch containing flurbiprofen, and to demonstrate the feasibility of flurbiprofen administration through the intact skin using adhesive type patch preparation. For this purpose, two pressure sensitive adhesives, Polyisobutylene(PIB) and $Gelva^{\circledR}737$, were selected from the chemical grade of polymers, and the adhesive type patches of flurbiprofen were prepared. The release rate of flurbiprofen from the PIB-based adhesive patch was higher than that from $Gelva^{\circledR}737$ based adhesive patch. The release rate of flurbiprofen from the PIB-based A-type patch with 1.0mm, 1.5mm or 2.0mm thicknesses followed the first order kinetics. In the skin permeation study, using male hairless mouse skin, a monophasic skin permeation profile was observed with 1% flurbiprofen loading dose. The inclusion of palmitic acid or SLS(0.25~0.5%) as an enhancer produced a remarkable enhancement in the skin permeation rate of flurbiprofen, and the percentile ratio of drug and enhancer appeared to be important for the effective enhancement. In the in vivo percutaneous absorption study, the plasma concentration of the optimal formulation was significantly (p<0.01) higher than that of the conventional cataplasma ($Bifen^{\circledR}$). These studies demonstrate a good feasibility of flurbiprofen administration through the intact skin using a transdermal patch, and show a possibility of the development of flurbiprofen patches.

• Journal of Korea Society of Industrial Information Systems
• /
• v.19 no.1
• /
• pp.43-52
• /
• 2014

P-wave characteristic in the human electrocardiogram (ECG) is important in the diagnosis of atrial conduction pathology. In this paper, we measured an ECG signal from patient with cardiovascular disease using one lead ECG electrode system which is based on the wireless cardiac monitoring system. And we detected a P-wave in ECG signal using the complex-valued continuous wavelet transforms (CWT) according to two kinds of patch type electrodes such as an existing narrow patch type electrode and the improved wide patch type electrode presented in this paper. Also, we compared the characteristics in detecting the P-wave in terms of the magnitude and the width of P-waves. From the results of comparison we found that the width and the magnitude of P-wave detected using the wide patch type electrode is improved to be interpreted easier compared to those using the narrow patch type electrode. Furthermore, we have also proven that the complex-valued CWT can be used as a robust detector for P-wave in ECG signal analysis.

• Journal of the Semiconductor & Display Technology
• /
• v.22 no.4
• /
• pp.142-147
• /
• 2023

This paper presents a novel design of a differential patch antenna for 60-GHz millimeter-wave applications. The design process of the back-to-back (BTB) patch antenna is based on the conventional single-patch antenna. The initial design of the BTB patch antenna (Type-I) has a patch size of 0.66 × 0.98 mm² and a substrate size of 0.99 × 1.48 mm². It has a gain of 1.83 dBi and an efficiency of 94.4% with an omni-directional radiation pattern. A 0.4 mm-thick high-resistivity silicon (HRS) is employed for the substrate of the BTB patch antenna. The proposed antenna is further analyzed to investigate the effect of substrate size and resistivity. As the substrate resistivity decreases, the gain and efficiency degrade due to the substrate loss. As the substrate (HRS) size decreases approaching the patch size, the resonant frequency increases with a higher gain and efficiency. The BTB patch antenna has optimal performances when the substrate size matches the patch size on the HRS substrate (Type-II). The antenna is redesigned to have a patch size of 0.81 × 1.18 mm² on the HRS substrate in the same size. It has an efficiency of 94.9% and a gain of 1.97 dBi at the resonant frequency of 60 GHz with an omni-directional radiation pattern. Compared to the initial design of the BTB patch antenna (Type-I), the optimal BTB patch antenna (Type-II) has a slightly higher efficiency and gain with a considerable reduction in antenna area by 34.8%.

• International Journal of Aeronautical and Space Sciences
• /
• v.6 no.1
• /
• pp.17-26
• /
• 2005

An optical phase tracking technique for an extrinsic Fabry-Perot interferometer (EFPI) is proposed in order to overcome interferometric non-linearity. Basic idea is utilizing strain-rate information, which cannot be easily obtained from an EFPI sensor itself. The proposed phase tracking system consists of a patch-type EFPI sensor and a simple on-line phase tracking logic. The patch-type EFPI sensor comprises an EFPI and a piezoelectric patch. An EFPI sensor itself has non-linear behavior due to the interferometric characteristics, and a piezoelectric material has hysteresis. However, the composed patch-type EFPI sensor system overcomes the problems that can arise when they are used individually. The dynamic characteristics of the proposed phase tracking system were investigated, and then the patch-type EFPI sensor system was applied to the active suppression of flutter, dynamic aeroelastic instability, of a swept-back composite plate structure. The proposed system has effectively reduced the amplitude of the flutter mode, and increased flutter speed.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2004.05a
• /
• pp.568-574
• /
• 2004

On-line phase tracking of an extrinsic Fabry-Perot interferometer (EFPI) and experimental vibration control of a composite beam with a sensing-patch are investigated. We propose a sensing-patch for the compensation of the interferometric non-linearity. In this paper, a sensing-patch that comprises an EFPI and a piezo ceramic(PZT) is fabricated and the characteristics of the sensing-patch are experimentally investigated. A simple and practical logic is applied for the real-time tracking of optical phase of an interferometer. Experimental results show that the proposed sensing-patch does not have the non-linear behavior of conventional EFPI and hysteresis of piezoelectric material. Moreover, it has good strain resolution and wide dynamic sensing range. Finally, the vibration control with the developed sensing-patch has been performed using Fuzzy logic controller, and the possibility of sensing-patch as a sensoriactuator is considered.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.13 no.9
• /
• pp.956-963
• /
• 2002

A linearly polarized folded type and H-shape slit folded type microstrip patch antenna at GPS(center frequency:1.575 GHz) were designed and fabricated by folding a conventional single $\lambda_{g}/2(\lambda_{g}:wavelength)$ rectangular patch a half along the length direction at the center of patch and inserting ground plane in the middle. As a result, two types of omnidirectional radiation patterns for E-plane (for zx-plane) in the direction of the length of patch and H-plane (for xy-plane) have been acquired. The experimental results show that the average gains of folded type and slit folded type for omnidirectional E-plane and H-plane are -1.5 dBd (-2.4 dBd) and -3.27 dBd(-2.5 dBd). Slit folded type microstrip patch antenna was more miniaturized than folded type microstrip patch antenna by 27.5 %. In case of slit folded type antenna, average gains of omnidirectional radiation pattern for E & H-plane are almost same.