• Title/Summary/Keyword: Patch test

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The patch tests and convergence for nonconforming Mindlin plate bending elements

  • Park, Yong-Myung;Choi, Chang-Koon
    • Structural Engineering and Mechanics
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    • v.5 no.4
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    • pp.471-490
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    • 1997
  • In this paper, the classical Irons' patch tests which have been generally accepted for the convergence proof of a finite element are performed for Mindlin plate bending elements with a special emphasis on the nonconforming elements. The elements considered are 4-node and 8-node quadrilateral isoparametric elements which have been dominantly used for the analyses of plate bending problems. It was recognized from the patch tests that some nonconforming Mindlin plate elements pass all the cases of patch tests even though nonconforming elements do not preserve conformity. Then, the clues for the Mindlin plate element to pass the Irons' patch tests are investigated. Also, the convergent characteristics of some nonconforming Mindlin plate elements that do not pass the Irons' patch tests are examined by weak patch tests. The convergence tests are performed on the benchmark numerical problems for both nonconforming elements which pass the patch tests and which do not. Some conclusions on the relationship between the patch test and convergence of nonconforming Mindlin plate elements are drawn.

Anti-inflammatory and Analgesic Activities, and Skin Irritation Test of Piroxicam Patch (피록시캄 패취제의 소염, 진통 효능 및 피부자극시험)

  • 고광호;조미정;이장훈;노민수;류재련;이진화;안재석;태주호;민동선
    • Biomolecules & Therapeutics
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    • v.2 no.1
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    • pp.71-76
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    • 1994
  • Anti-inflammatory and analgesic activities and skin irritation of piroxicam patch were investigated. Piroxicam patch increased the pain threshold in rat hind paw inflamed by carrageenan and inhibited writhing induced by acetic acid in mice. Piroxicam patch also inhibited the carrageenan-induced edema in rat hind paw as well as the increased vascular permeability induced by histamine in rats. In adjuvant arthritis of rats, piroxicam patch showed anti-inflammatory effects. Skin irritation of piroxicam patch was tested in Newzealand White rabbits and evaluated by Primary Irritation Index of Draize. The results from skin irritation test showed that piroxicam patch seemed practically non-irritating. The result from the present study indicates that piroxicam may be useful without serious side effects as anti-inflammatory analgesics in this patch form.

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Effects of Lidocaine Patch Application to Decrease Pain and Fear during Blood Sugar Test in Elderly Patients with DM (리도카인 패치 적용이 당뇨노인환자의 혈당검사 시 통증과 두려움에 미치는 효과)

  • Kim, Se Young;Kim, Jin;No, In Sun
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.23 no.1
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    • pp.12-20
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    • 2016
  • Purpose: This study was done to examine the effects of lidocaine patch application to decrease pain and fear during blood sugar testing in elderly patients with DM. Methods: The participants were 56 elderly patients admitted to J geriatric hospital in G city, Korea. Of the elderly patient, 27 were assigned to the experimental group and 29 to the control group. Participants in the experimental group applied a lidocaine patch on the fingertip for 30 minutes before a blood sugar test. The control group applied a plaster on the fingertip. Pain was evaluated using a visual analogue scale and fear using the Procedure Behaviour Check List. The results were compared using paired t-test and t-test. Results: The scores for pain and fear were significantly lower in the experimental group compared to the control group. Conclusion: The lidocaine patch was found to be an effective local anesthetic to relieve pain and fear during blood sugar test in elderly patients with DM without any severe adverse events.

Skin Irritation Test of Clonidine Patch (Clonidine Patch에 피부자극성 시험)

  • 이영순;박우일;고광호
    • Biomolecules & Therapeutics
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    • v.4 no.2
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    • pp.202-204
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    • 1996
  • Clonidine, an antihypertensive drug, stimulates postsynaptic $\alpha_2$adrenergic receptors in the CNS and lowers arterial pressure by erects on both cardiac output and peripheral resistance. However, many patients experience that sedation and xerostomia occured upon oral administration of clonidine. These side effects are due to high plasma peak concentration and can be avoided when clonidine is given transdermally. In this study, we performed the skin irritation test for transdermal administration of clonidine patch on New Zealand white rabbits. Twelve New Zealand white rabbits were divided into two groups according to the dose levels, respectively. After transdermal administration of clonidine patch with two doses, clinical manifestations, body weight loss and postmortem findings were observed. We could not find any significant evidence of skin irritation by transdermal administration of clonidine patch.

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Skin Patch Test and Antibacterial Properties of the Anti-microbial Agent and Melamine Resin Blend Treated Fabric (멜라민 수지와 항균제 혼합 수지 가공 직물의 항균성과 피부 적합성)

  • Chun, Tae-Ill;Park, Jung-Whan
    • Fashion & Textile Research Journal
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    • v.7 no.1
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    • pp.81-84
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    • 2005
  • Skin patch test and antibacterial properties of the reaction products between poly(hexamethyl biguanide) hydrochloride and trimethylol melamine on textile fabrics were examined. Antibacterial activities of anti-microbial agent treated samples are very good. The reduction ratios against four kinds of colonies are 99.9 % after repeated laundering ten times. Skin patch test results for anti-microbial agent treated samples are almost-negative by Hi-scope judgement and macroscopical judgement.

Patch Plate Repair Method for Steel Structures Combining Adhesives and Stud Bolts

  • Ishikawa, T.;Ikeda, T.
    • International journal of steel structures
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    • v.18 no.4
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    • pp.1410-1419
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    • 2018
  • Recently, a repair method by bonding patch plates is being applied to corroded steel structures. However, one of the issues of patch plate bonding repair is the brittle debonding of the patch plates. Generally, when the delamination of the patch plates occurs, the composite effect acting between the steel members and patch plates abruptly decreases. Therefore, to prevent the brittle debonding of the patch plates, a repair method combining an adhesive and stud bolts is proposed. Till date, tensile and compressive tests have been performed for the proposed method. In this study, plate bending tests were conducted to verify the effectiveness of this method under bending conditions. Furthermore, two types of epoxy resin-based adhesives were prepared to evaluate the effectiveness of the proposed method with different adhesive properties. The test results show that the proposed method is able to prevent the brittle debonding of the patch plates in the case of both epoxy resins.

A Empirical Study on the Patch Impact Assessment Method for Industrial Control Network Security Compliance (산업제어망 보안 컴플라이언스를 위한 패치 영향성 평가 방안에 관한 실증 연구)

  • Choi, Inji
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.30 no.6
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    • pp.1141-1149
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    • 2020
  • Most of the industrial control network is an independent closed network, which is operated for a long time after installation, and thus the OS is not updated, so security threats increase and security vulnerabilities exist. The zero-day attack defense must be applied with the latest patch, but in a large-scale industrial network, it requires a higher level of real-time and non-disruptive operation due to the direct handling of physical devices, so a step-by-step approach is required to apply it to a live system. In order to solve this problem, utility-specific patch impact assessment is required for reliable patch application. In this paper, we propose a method to test and safely install the patch using the regression analysis technique and show the proven results. As a patch impact evaluation methodology, the maximum allowance for determining the safety of a patch was derived by classifying test types based on system-specific functions, performance, and behavior before and after applying the patch. Finally, we report the results of case studies applied directly to industrial control networks, the OS patch has been updated while ensuring 99.99% availability.

Dental materials in patients with oral mucosal disease based on the results of patch test study (구강점막질환환자에서 치과재료를 이용한 첩포시험 결과에 대한 고찰)

  • Jeong, Sung-Hee;Kim, Ji-Su;Kim, Kyung-Hee;Ok, Soo-Min;Heo, Jun-Young;Ahn, Yong-Woo
    • The Journal of the Korean dental association
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    • v.52 no.2
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    • pp.96-104
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    • 2014
  • The aim of this study was to investigate the frequency of positive patch test reaction to dental materials in patients with oral mucosal diseases. Epicutaneous patch test was performed in 110 patients with oral mucosal diseases; 41 patients with oral lichen planus(OLP), 44 patients with burning mouth syndrome(BMS), 25 patients with other oral mucosal diseases including recurrent aphthous ulcer and mucous membrane pemphigoid. The obtained results were as follows: Oral gold restorations were most common in patents with oral mucosal diseases and porcelain fused metal crown, implant appeared in the order. 33 of 110 patients did not appear skin reactions (negative, 30%) and 77 patients (positive, 70%) had skin reactions including redness, rash, blisters. Dental materials causing positive reaction to patch test were mainly as gold-sodium-thiosulfate (26.7%), nickel sulfate(Ni) (22.7%), cobalt chloride(Co) (14.7%), palladium chloride(Pd) (11.9%), potassium dichromate (10.7%) in order, respectively. In conclusion, old metal restorations could be the cause of oral mucosal diseases and epicutaneous patch test could be used as a tool to improve the oral conditions.

The Study on Skin 1st Patch Test of Fermented Hydrolysate from Abalone(Haliotis discus hannai Ino) (발효 전복 추출물의 피부자극에 관한 연구)

  • Lee, Chung-Woo;Hong, Kyung-Hee;Chun, Yong-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.421-424
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    • 2016
  • This study evaluated the efficacy and the skin safety and stability of a cosmetic that is an applied water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino), which was produced at the south coast of Korea. In the patch test, purified water, 1,3-butylene glycol and liquid crystal lotion were used as the reference group, and water extract and fermented hydrolysate of abalone and lotion formulation of water extract and fermented hydrolysate of abalone were used as the sample group. The results of patch test showed no irritation on skin among in any of the test groups. Therefore, the water extract and fermented hydrolysate of abalone (Haliotis discus hannai Ino) are safe for human skin.

A simple method of stiffness matrix formulation based on single element test

  • Mau, S.T.
    • Structural Engineering and Mechanics
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    • v.7 no.2
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    • pp.203-216
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    • 1999
  • A previously proposed finite element formulation method is refined and modified to generate a new type of elements. The method is based on selecting a set of general solution modes for element formulation. The constant strain modes and higher order modes are selected and the formulation method is designed to ensure that the element will pass the basic single element test, which in turn ensures the passage of the basic patch test. If the element is to pass the higher order patch test also, the element stiffness matrix is in general asymmetric. The element stiffness matrix depends only on a nodal displacement matrix and a nodal force matrix. A symmetric stiffness matrix can be obtained by either modifying the nodal displacement matrix or the nodal force matrix. It is shown that both modifications lead to the same new element, which is demonstrated through numerical examples to be more robust than an assumed stress hybrid element in plane stress application. The method of formulation can also be used to arrive at the conforming displacement and hybrid stress formulations. The convergence of the latter two is explained from the point of view of the proposed method.