• Title/Summary/Keyword: Passages

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The dependence of nitric oxide synthase inhibition caused by cigarette smoking extracton the cellular aging of bovine aortic endothelial cells

  • Le, VuQuynhAnh;Kim, Yang-Hoon;Min, Jiho
    • Environmental Analysis Health and Toxicology
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    • v.29
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    • pp.10.1-10.6
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    • 2014
  • Objectives Cigarette smoking had been recorded as the main cause of impaired endothelium-dependent vasodilation in smokers by reducing nitric oxide (NO), a production of endothelial nitric oxide synthase (eNOS). However, the mechanism of NO impairment via eNOS activity is unclear until now. In this study, cell passage is suggested to be a relevant factor to eNOS expression under cigarette smoking stress. Methods Bovine aortic endothelial cells (BAECs) were chosen as the research subject with passages ranking from 6 to 9 (6P to 9P). After exposure of cigarette smoking extract (CSE) solution, MTT assay and Western blot method were performed to check the cell viability as well as eNOS protein concentration. In these experiments, four concentrations of CSE at 0.5, 1, 2, and 4% were selected for treatment. Results Our results showed that cells almost died at 4% of CSE. Besides, eNOS protein mass had a linear decrease under the increase of CSE concentration. In addition, the effect of CSE on eNOS expression was dissimilar between different passages. Conclusions This study indicated that CSE had effect on both cell viability and eNOS expression. Besides, a reduction in protein mass was matched with the decrease of cell viability due to CSE tress. Last but not least, the response of eNOS protein to different concentration of CSE at different passages was disparate, making the hypothesis about cell passage related inhibition of eNOS caused by CSE solution.

Current Status and User Satisfaction Analysis of Neighborhood Park for Barrier Free Friendly Park - A Focus on Cheonho Park, Gandaemae Park and Hunlyunwon Park - (무장애친화공원화를 위한 근린생활권 공원의 현황 및 이용자 만족도 분석 - 천호공원, 간데메공원, 훈련원공원을 대상으로 -)

  • Kang, Hyun-Kyung;Lee, Su-Ji;Back, Seung-Jun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.19 no.1
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    • pp.135-153
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    • 2016
  • This study is aimed at grasping improvement factors of Cheonho Park, Gandaemae Park and Hunlyunwon Park as barrier free friendly parks. For this study, current status of parks, users' state and satisfaction were analyzed in October, 2014 and September, 2015. To detect current status, period of designing, whole size, facility pavement green space area, and main spaces were examined. As for BF status, mediation facilities, leading and guidance facilities, convenient facilities and BF pedestrial passage were analyzed. Also, It examined user behavior and satisfaction by accessibility, convenience and safety items. As a result of status analysis, three parks were designed in 1997~1998. The size of parks were $15,180m^2{\sim}26,697m^2$. As for mediation facilities, the slopes of walking-passage in Cheonho Park and Gandaemae Park were flat. The rate of leading-guidance facilities was 72.7%~93.4%. In the three parks, the effective width of safe pedestrian space within BF pedestrial passages was more than 1.8m. In Cheonho Park and Gandaemae Park, more than 50% of soil and urethane were used as paving materials. Users were the most satisfied with accessibilities in Cheonho Park due to flat-typed walking passages. In convenience, when it comes to using benches and pergolas, it showed significantly different satisfaction in every park. In safety, there were also considerable difference in every park. Overall, it was analysed that the satisfaction with information for safety and facilities was significantly low. Against this backdrop, this study suggests three considerations to recreate parks as barrier free friendly parks. 1) Flat-typed walking passages and enough parking areas near parks should be constructed. 2) Additional rest furniture for convenience should be installed and complemented. 3) Walking oriented-spatial safe facilities for safety should be differently supplemented.

Marine traffic survey to improve safety of vessel traffic at Busan South Port (부산남항 선박통항 안전성 향상을 위한 해상교통량 조사)

  • Kim, Seok-Jae;Park, Moon-Gap;Lee, Yoo-Won
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.47 no.4
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    • pp.428-434
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    • 2011
  • To establish a vessel safety management system for improving the safety of vessel's traffic and preventing vessel's traffic accidents, the state of marine traffic in the Busan South Port was investigated and analyzed as preliminary survey of the countermeasures. As a result of the study, there are 1,158 vessels in a day, 48 vessels in an hour, and the maximum traffic is about 118 vessels between 16:00 and 17:00 hours everyday, which requires to establish and operate a traffic control system necessarily for ensuring vessel's traffic safety. Furthermore, passages of tanker, passenger ship, cargo vessel and government vessel showed to sail along main traffic lane to be obtained enough sea depth at the survey area. However, passages of fishing vessel and launch showed to sail freely at all survey area owing to outstanding maneuverability and a shallow draft. Some vessels of launch sailed along main traffic lane, but other vessels crossed to sail it. The passages to cross main traffic lane is higher the risk of collision. Therefore, safety measures are urgently needed for the operation of the Busan South Port management system and the prevention of marine pollution.

A Theoretical Study on the Wildlife Passage for Connecting Fragmented Habitat(I)- In the case of Wildlife Passage Types and Design Process (분절된 서식처의 연결을 위한 생태이동통로에 관한 이론적 연구(I) - 유형구분 및 조성절차를 중심으로 -)

  • 김귀곤;최준영
    • Journal of the Korean Institute of Landscape Architecture
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    • v.26 no.2
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    • pp.293-307
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    • 1998
  • This study has been divided into two parts, 1) literature review and 2) a case study. Based on literature review and case studies found in Korea and abroad, this study aimed at classifying wildlife passages and establishing their development procedures in order to establish a theoretical ground for the development of wildlife passage as a way to link habitats that have been fragmented by the construction of roads and other developments. The results of the literature review are as follows : 1) Impact of road construction on surrounding ecological environment is found in various aspects. Along with damage of habitats as direct impact, decrease of biodiversity and simplification of species due to limited breeding and movement are cited as possible indirect impact. 2) In order to lessen the impact generated from fragmented habitats, various types of wildlife passage are being developed in Europe and are showing positive results. 3) In Korea, interests on animal passages have been rising recently. The ministry of Environment and local authorities are establishing development plans for the passages. However, practical materials on the usefulness of adoped methods are not available.4) In order to create an effective wildlife passage, decisions have to be made first on basic factors of planning and designing such as ecosystem rehabilitation methods and surveys on wildlife movement routes and habitat environment. Based on this, in a planning and designing stage, the location and type of a passage, size and measures to attract animals and prevent a collision need to be finalized. This should be followed by a series of process of maintenance, management and monitoring after the development. Based on the results of a theoretical study to develop an wildlife passage, Part 2 of this study deals with the results of an experiment through a specific planning and design that includes a process of ecological surveys, site selection, type selection, ecosystem infrastructure, planting design and construction details on an actual study area and presents them as a model project.

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A Study of Improvement on Pedestrian Level of Service by Pedestrian Satisfaction - Focused on Lower Floor Building Use in Seoul - (보행만족도에 따른 보행서비스수준 지표개선 - 서울시 저층부 용도를 대상으로 -)

  • Moon, Young-gi;Kim, Dong-joon;Han, Jei-hyun;Kang, Jun-mo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.38 no.6
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    • pp.979-990
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    • 2018
  • The main purpose of this study is to discriminate the pedestrian environment by simple calculation such as using the matrix from pedestrian level of service. However, the general use of pedestrian level of service cannot discriminate the environment of footpaths, especially in Seoul. Most of the passages in Seoul are showing level A, which means most passages are spacious, but pedestrians don't agree that passages are wide enough to walk. In conclusion, comparing the pedestrian level of service with pedestrian satisfaction in different circumstances such as use of building in lower floors. Test areas are 1,157 spots in Seoul. First, The new pedestrian level of service shows equally in all spots. Second, spots where the highest pedestrian satisfaction are mostly in level B or level C, thus planning the walkways in future, level B or level C is recommended in most cases.

A Study on the Reliability of Storage/Retrieval for Warehouse Layout Based on Shuttle Rack System (셔틀랙 기반 물류센터의 레이아웃별 반출입 신뢰성에 관한 연구)

  • Seung-Pil Lee;Hyeon-Soo Shin;Hwan-Seong Kim
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2021.11a
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    • pp.101-103
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    • 2021
  • With the rapid increase in the quantity of goods transported worldwide, companies are now started to show great interest in unmanned automated warehouses along with related research and development due to the increase of warehouse efficiency and reduction warehouse manpower. In a number of small warehouses, shuttle rack-based layouts that can handle inventory flow flexibly. However, the shuttle rack-based logistics center does not operate in case of emergency situations (faults, power outages, etc.), which seriously affects the efficiency and inventory management of the entire logistics center. Accordingly, in shuttle rack-based logistics center, we have classified various shuttle passages and RTV passages by layout and have analyzed its characteristics and types, along with derived reliability for each layout. The loading rate was also derived differently according to the number of passages, and have compared and analyzed reliability and loading rate for each layout.

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A statistical study of the foreign bodies in the food and air passages (식도 및 기도이물의 통계적 고찰)

  • 박근목;우영태;김은우;박해수
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1977.06a
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    • pp.9.2-9
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    • 1977
  • A Statistical study was carried out on 64 cases of the foreign bodies in the food and air passages, who visited the Dept. of Otolaryng. of Korea General Hospital from Jan. 1971 to Dec. 1976. The following results were obtained. 1. The total number of foreign bodies were 64 cases, which is approximately 0.69% of the total number of new patients who visited the out patient department during the same period. Among them 55 cases were foreign bodies in the food passage and 9 cases were foreign bodies in the air passage. The ratio between the food and air passages was about 6.1 : 1. 2. The frequently encountered foreign bodies in the esophagus were coin, bone, meat and food particle in order. Bean and peanut were male and 31 case the most frequent foreign bodies in the air passage. 3. In sex distribution, 33 cases were male and 31 cases were female, and the ratio between male was 1.1:1. 4. In the age distribution, 35 cases (54.7%) of all foreign bodies were under 5-year-old, especially coin was 96.2%. 5. The most prevalent site of lodgement in the food passage was the 1st esophageal narrowing, which corresponds to 69.1%. 6. In duration of lodgement, 38 cases (69.1%) of foreign bodies in the food passage were removed within 24 hours, and the longest duration was 90 days. 7. Almost all of the foreign bodies in the food and air passages were removed under local or no anesthesia by esophagoscopy, laryngoscopy.

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Analysis of the Continuity of Reading Passages in the 5th and 6th Grade Elementary School English Textbooks Based on Readability (이독성을 통한 초등학교 5, 6학년 영어 교과서 읽기 지문의 연계성 분석)

  • Jang, Hankyeol;Lee, Je-Young
    • The Journal of the Korea Contents Association
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    • v.22 no.6
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    • pp.116-124
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    • 2022
  • The purpose of this study is to examine the vertical and horizontal continuity between grades and publishers, respectively, by analyzing the readability of reading passages included in English textbooks for 5th and 6th grades of elementary school. In order to do so, a corpus was constructed with the reading passages contained in 10 textbooks, and the reading passages in each textbook were analyzed through Coh-Metrix. Also, it was examined whether there was a statistically significant difference between grades and publishers in readability through one-way ANOVA. The results are as follows. First, as a result of analyzing the difference in readability between publishers within the same grade, there was a statistically significant difference between fifth-grade textbooks in the L2 readability index. Second, as a result of analyzing the vertical continuity between grades within the publisher, the difficulty of textbook A was higher in grade 6 than grade 5 based on FRE and FKGL, which showed a statistically significant difference. On the other hand, when L2 readability was used as the standard, the difficulty of textbook B was lower in 6th grade than in 5th grade. This result seems to be because FRE and FKGL calculate readability based on sentence and word length, whereas L2 readability is based on content word overlap, word frequency, and syntactic similarity of sentences.