• 한국화재소방학회논문지
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• 제30권1호
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• pp.43-48
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• 2016

본 연구에서는 입자상 물질의 유해성을 포함하는 연소생성물 독성평가 기법의 개발을 위한 선행 연구로써, 입자상 물질의 위험성을 확인하기 위한 실험을 수행하였다. 실험은 동일 시료의 가스유해성 시험을 통하여 교반상자와 피검상자 사이 Membrane 필터 설치 유무에 따른 평균행동정지시간의 변화를 분석함으로써, 연소생성물 중 입자상 물질을 필터링하여 노출시킨 경우와 입자상 물질을 포함한 연소생성물을 노출시킨 경우의 시험 결과를 비교 분석하였다. 시험결과 필터 장착 시 실험용 쥐의 평균행동 정지시간이 목재 시료의 경우 최대 264% 증가하였으며, 우레탄 시료의 경우 최대 179% 증가함을 확인하였다. 이를 통해 입자상 물질의 유해성 및 이에 대한 정량적 독성평가의 필요성을 확인하였다.

• 전기학회논문지
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• 제58권5호
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• pp.968-975
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• 2009

The goals of this research are to understand the regeneration characteristics in diesel particulate filter using the HC injection. This research emphasized on the development of Continuously Regenerating DOC/DPF and HC technology which was the best particulate matters removing technology of current existing technology. This experimental study has been conducted with equipped a Continuously Regenerating DOC/DPF and HC injection on displacement 2.0, 3.3 $\ell$ diesel engine and compared in terms of particulate material and emission. In this study, we could constructed 3 kinds of database according to quantity of temperature to decide the HC injection quantity and develop DOC/DPF ECU algorithm.

• 대한화학회지
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• 제38권10호
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• pp.726-733
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• 1994

대기부유분진(air particulate material)중에 존재하는 다환방향족탄화수소(polycyclic aromatic hydrocarbons, PAH)를 신속하고 정확하게 분석하기 위하여 대기부유분진 시료를 10ml의 초임계유체($N_2O$ )로 30분간 추출 후 별도의 전처리와 농축과정 없이 GC/MS에서 분석하여 분석시간과 분석과정을 단축 및 단순화하였다. 시료로서 NBS 대기부유분진 인증표준기준물질(certified particulate reference material, CRM)1649와 서울의 도심에서 채취한 대기부유분진 시료를 이용하여 기존의 추출법 및 분석방법과 비교하였다. 그 결과 본 분석방법은 기존의 분석법에 비해 회수율은 상대적으로 작았으나 재현성이 좋았으며 분석과정이 간단하고 분석시간이 현저히 단축됨을 알 수 있었다.

• 한국해양공학회지
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• 제24권1호
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• pp.99-105
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• 2010

The concentration and size analysis of in-situ suspended particulate material were measured using an optical instrument, LISST-100, in the bottom layer at the three inlets of the Seomjin River Estuary, mouth of Gwangyang bay, and Gwangyang bay-side of the Namhae Bridge. In the Seomjin river estuary and mouth of Gwangyang bay-side of the Namhae Bridge, the in-situ mean grain size of the suspended material changed from a uni-modal distribution with a dominant peak at a coarse fraction to a bi-modal distribution with a secondary peak at the finer particles. Seomjin River. The interactions between suspended particulate concentration and beam attenuation coefficient of suspended particulate matters depended on the supply of finer and coarser particles in the mouth of Gwangyang Bay and Seomjin River. So, interactions reflected difference of the concentration, mean size and sorting of suspended particulate matters. The difference of interaction showed dynamic behaviors to the resuspension and deflocculation processes increased river discharge. This showed that it may be possible to use the interactions between the suspended particle concentration and beam attenuation coefficient to monitor the temporal and spatial distributions of in-situ particles.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2005년도 제31회 KOSCO SYMPOSIUM 논문집
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• pp.99-103
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• 2005

This study focused on the use of orimulsion in industrial combustion systems. Orimulsion is a bitumen-in-water emulsified fuel, which contains a thirty percent water. Orimulsion has relatively high levels of sulfur and nitrogen compared to many fuel oils, and has been the subject of much debate regarding the environmental impacts of its use. The goal of this research is to analyse the effect of flash spray combustion characteristics of orimulsion on NOx and particulate material reduction. For the flash spray of orimulsion, it is heated by $150^{\circ}C$. The effects of fuel heating temperatures on NOx and particulate material emissions were investigated experimentally. As the fuel temperature was increased, NOx and particulate material concentrations in flue gas were decreased.

• 한국연소학회지
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• 제10권4호
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• pp.18-23
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• 2005

This study focused on the use of orimulsion in industrial combustion systems. Orimulsion is a bitumen-in-water emulsified fuel, which contains a thirty percent water. Orimulsion has relatively high levels of sulfur and nitrogen compared to many fuel oils, and has been the subject of much debate regarding the environmental impacts of its use. The goal of this research is to analyze the effect of flash spray combustion characteristics of orimulsion on NOx and particulate material reduction. For the flash spray of orimulsion, it is heated to $150^{\circ}C$. The effects of fuel heating temperatures on NOx and particulate material emissions were investigated experimentally. As the fuel temperature was increased, NOx and particulate material concentrations in flue gas were decreased.

• Journal of Pharmaceutical Investigation
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• 제40권spc호
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• pp.83-95
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• 2010

Over the years, nanoparticle drug delivery systems have demonstrated versatile potentials in biological, medical and pharmaceutical applications. In the pharmaceutical industry nanotechnology research has mainly focused on providing controlled drug release, targeting their delivery to specific organs, and developing parenteral formulations for poorly water soluble drugs to improve their bioavailability. Achievement in polymer industry has generated numerous polymers applicable to designing nanoparticles. From viewpoints of product development, a nanocarrier material should meet requirements for biodegradability, biocompatibility, availability, and regulatory approval crieteria. Albumin is indeed a material that fulfills such requirements. Also, the commercialization of a first albumin-bound paclitaxel nanoparticle product (Abraxane$^{TM}$) has sparked renewed interests in the application of albumin in the development of nanoparticle formulations. This paper reviews the intrinsic properties of albumin, its suitability as a nanocarrier material, and albumin-based parenteral formulation approaches. Particularly discussed in detail are albumin-based particulate injectables such as Abraxane$^{TM}$. Information on key roles of albumin in the nab$^{TM}$ technology and representative manufacturing processes of albumin particulate products are provided. It is likely that albumin-based particulate technology would extend its applications in delivering drugs, polypeptides, proteins, vaccines, nucleic acids, and genes.

• 한국입자에어로졸학회지
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• 제19권4호
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• pp.145-154
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• 2023

Granular bed filters are widely used to remove particulate matter in flue gas and are filled with various shapes of packing material. The packing material plays an important role in determining the overall collection performance, such as pressure drop and collection efficiency. The pressure drop of a granular bed filter has been calculated using the Ergun equation, while the collection efficiency has been predicted using the log-penetration equation based on the single sphere theory. However, a prediction equation of collection efficiency for a granular bed filter filled with non-spherical packing materials has not been suggested yet. Therefore, in this study, three different shapes of packing materials (sphere, cylinder, and irregular) were prepared to propose a prediction equation. The pressure drop and collection efficiency in a granular bed filter filled with each shape of packing material were measured experimentally and compared with theoretically predicted values. We found that experimentally measured pressure drops matched well with values theoretically predicted using the Ergun equation considering the shape factor. However, experimental collection efficiencies were higher than theoretical ones predicted by the log-penetration equation using the single sphere theory. We modified the log-penetration equation by employing a shape factor and found a good relationship between experimental and theoretical collection efficiencies.

• Journal of Pharmaceutical Investigation
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• 제21권3호
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• pp.155-160
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• 1991

Particulate is the foreign insoluble material in injectable solution inadvertently present in a given product. Considerable efforts have been made to avoid or minimize particulate contamination by pharmaceutical manufacturers during the production of parenteral products. Particulate contamination of the parenteral products can occur mainly during the opening (cutting) the container immediately before clinical use. In this study, particulate contamination generated during the opening process of ampoules (conventional type, 1-point and color-break ampoules) was compared with that of a prefilled injectable container (prefilled syringe). The particles were examined under a microscope after filtration of the total fluids in the containers. Particles having wide range of size distribution were found from all the ampoules tested. The contamination from the I-point ampoule and colorbreak ampoule was much less than from the conventional ampoule. Glass particles generated by cutting the glass-made ampoules seemed a principal source of the particulate contamination. The glass-partiaulte contamination could be improved substantially by replacing the ampoule containers with the prefilled syringe. Prefilled syringe, which can be used without any cutting process. did not generate particulates during the use. Therefore, it was concluded that prefilled syringe is most preferable container for the small volume parenteral (SVP) fluids in terms of particulate contamination.

• Smart Structures and Systems
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• 제1권2호
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• pp.217-233
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• 2005

Elastic and electromagnetic waves can be used to gather important information about particulate materials. To facilitate smart geophysical characterization of particulate materials, their fundamental properties are discussed and experimental procedures are presented for both elastic and electromagnetic waves. The first application is related to the characterization of particulate materials using shear waves, concentrating on changes in effective stress during consolidation, multi-phase phenomena with relation to capillarity, and microscale characteristics of particles. The second application involves electromagnetic waves, focusing on stratigraphy detection in layered soils, estimation of void ratio and its spatial distribution, and conduction in unsaturated soils. Experimental results suggest that shear waves allow studying particle contact phenomena and the evolution of interparticle forces, while electromagnetic waves give insight into the characteristics of the fluid phase and its spatial distribution.