• The Journal of Korean Medicine
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• v.18 no.1
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• pp.299-315
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• 1997

The present experiments were designed to investigate the effects of Samsaengyeum. water extracts on the Cardiovascular System in the Experimental Animals. Thus, the changes of blood pressure and heart rate were measured after oral administration. Measurement of Mortality rate was observed for measuring the effect of Samsaengyeum water extract Samsaengyeum water extract against pulmonary thromboembolism induced by collagen the mixture(0.1me/10g, 2mg/kg B.W) plus serotonin(5mg/kg B.W) in mouse. The effect of Samsaengyeiim water extract was examined by observing the change of collagen-induced platelet aggregation, coagulation activity, ex vivo and in vitro fibrinolytic activity of euglobulin fraction in rats. The results were summarized as followings. 1. Samsaengyeum dropped the blood pressure in spontaneous hypertensive rat. 2. The drug increased the auricular blood flow in rabbit. 3. The drug relaxed the artery contraction by pretreated norepinephrine in rat. 4. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 5. The drug inhibited the platelet aggregation in rat. 6. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 7. The drug reduced the fibrinogen lyses time and increased the lyses area of rat. 8. Samsaengyeum reduced fibrinogen lyses time of rat in vitro assay. According to the above mentioned results, Samsaengyeum increased the blood flow and dropped the blood pressure by the dilation of blood vessel. And the drug inhibited the platelet aggregation.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.2
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• pp.1-17
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• 2006

Purpose : The Purpose of this research was to investigate the effects of antithrombotic activities of Haenggyonghonghwatang (HGHHT). Methods : Measured the effect which was given to blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD soulution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that is caused from the administration of platelet aggregation regent. Each of the groups consisted in 8 mice, was divided into Normal, Control, and HGHHT. All of these 3 group were supplied a saline solution and after an hour the control group brought the dextran extravasated blood. Also the HGHHT group was dosed to the experimental mice with Oral Zonde one day before the experiment. After that, the mice were abstained from food. And then we gave a measured amount of it before an hour. Finally, it gave rise to dextran extravasated blood as well as the Control group. Results : The results were obtained as follows. HGHHT inhibited platelet aggregation induced by ADP and epinephrine significantly as compared with the control group. HGHHT showed fibrinolytic activity insignificantly as compared with the control group. HGHHT increased blood flow rate significantly as compared with the control group in vitro, but insignificantly as compared with the control group in vivo. HGHHT inhibited pulmonary embolism induced by collagen and epinephrine(inhibitive rate 50%). HGHHT increased number of platelet, fibrinogen amount and shortened prothrombin time, activated partial thromboplastin time significantly as compared with the control group in thrombus model induced by dextran. Conclusion : HGHHT is effective antithrombotic activity from experimental result.

• Journal of Chest Surgery
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• v.10 no.2
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• pp.299-314
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• 1977

Clinical experience on 16 cases of open heart surgery under the extracorporeal circulation with mild or moderate hypothermia and partial hemodilution technique at the National Medical Center during the period from June 1976 to October 1977. Nine of sixteen were congenital heart disease and seven were acquired heart disease. The age of the patient ranged between 6 and 48 years. The body weight varied from 18.5kg to 60kg and body surface area 0. 79-1.70m2. The average priming volume of pump oxygenator was 2080 ml, which was consisted fresh ACD blood, buffered Hartmann`s solution, Mannitol, 50% dextrose in water and Vit. C. The average hemodilution rate was 27%. The average flow 2.3 L/min/m2 or 80 ml/min and the duration of perfusion varied from 31 min to 270 min with average of 107 min. The perfusion was carried out under the mild or moderate hypothermia using core cooling alone in 10 cases, core cooling and local myocardial cooling with $0-4^{\circ}C$ physiologic saline in 2 cases. From a hemodynamic point of view, the blood pressure dropped down around 80 mmHg after the initiation of perfusion follwed by increase to safety level and stable during the perfusion. The central venous pressure remained within normal limits. In most cases, hemoglobin and hematocrit decreased during and after the perfusion. Hemogiobin level was decreased, average of 20.6 %, hematocrit 18.6%, pletelets 55% postoperatively. Plasma hemoglobin increased moderately, from preperfusion average valve of 7.79 mg % to post-perfusion value of 54.7 mg %. Electrolytes changes during cardiopulmonary bypass showed definite hypokalemia but changes of Na, Ca were not definite. Arterial blood gas analysis during cardiopulmonary bypass suggested that the metabolic acidosis which was accompanied by respiratory alkalosis which was corrected postoperatively. As the opera tive complication, transient hemoglobinuria in 4 cases and neurological signs in 2 cases were all cured. There were 2 death cases and operative mortality rate was 12.5%.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.38 no.9
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• pp.943-954
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• 2010

In this study, a radial inflow type turbine was applied and the outer diameter of the turbine rotor was 108 mm. The turbine blade on a circular plate disc was designed as an axial-type because its partial admission rate was 1.4-4.1%. The turbine consisted of three stages. The performance test has been conducted with various admission rates, tip clearances and nozzle flow angles. The turbine output power was measured on each stage. The turbine performance was obtained in a wide rotational speed range in order to compare its performance according to various operating conditions. The net specific output torque was also measured to compare its overall performance. Computational analysis was conducted for predicting turbine performance. The computed results were in good agreement with the experimental results.

• Aerospace Engineering and Technology
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• v.1 no.1
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• pp.163-172
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• 2002

The turbine system composed of a nozzle and a rotor is used to drive turbopumps while gas passes through the nozzle, potential energy is converted to kinematic energy, which forces the rotor blades to spin. In this study, an aerodynamic design of a turbine system is investigated using compressible fluid dynamic theories with some pre-determined design requirements (i.e.,pressure ratio, rotational speed, required power etc.) obtained from a liquid rocket engine (L.R.E.) system design. For simplicity of a turbine system, impulse-type rotor blades for open type L.R.E. have been chosen. Usually, the open-type turbine system requires low mass flow rate compared to the close-type system. In this study, a partial admission nozzle is adopted to maximize the efficiency of the close-type turbine system. A design methodology of the a turbine system has been introduced. Especially, a partial admission nozzle has been designed by means of simple empirical correlations between efficiency and configuration of the nozzle. Finally, a turbine system design for a 10 ton thrust level of L.R.E is presented.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 1997.11a
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• pp.364-368
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• 1997

We have investigated Pt and RuO$_2$as a bottom electrode for a device application of PZT thin film. The bottom electrodes were prepared by using an RF magnetron sputtering method. We studied some of the property influencing factors such as substrate temperature, gas flow rate, and RF power. An oxygen partial pressure from 0 to 50% was investigated. The results show that only Ru metal was grown without supp1ying any O$_2$gas. Both Ru and RuO$_2$phases were formed for O$_2$partial pressure between 10∼40%. A Pure RuO$_2$ phase was obtained with O$_2$partial pressure of 50%. A substrate temperature from room temperature to 400$^{\circ}C$ was investigated with XRD for the film crystallinity examination. The substrate temperature influenced the surface morphology and the resistivity of Pt and RuO$_2$as well as the film crystal structure. From the various considerations, we recommend the substrate temperature of 300$^{\circ}C$ for the bottom electrode growth. Because PZT film growth on top of bottom electrode requires a temperature process higher than 500$^{\circ}C$, bottom electrode properties were investigated as a function of post anneal temperature. As post anneal temperature was increased, the resistivity of Pt and RuO$_2$was decreased. However, almost no change was observed in resistivity for an anneal temperature higher than 700$^{\circ}C$. From the studies on resistivity and surface morphology, we recommend a post anneal temperature less than 600$^{\circ}C$.

• Journal of Biomedical Engineering Research
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• v.25 no.4
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• pp.295-300
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• 2004

Coil embolization technique has been used recently to treat cerebral aneurysms. When a giant or a multilobular aneurysm are treated by roils, filling an aneurysm sac completely with coils is difficult and partial blocking of an aneurysm sac is inevitable. Blood flow characteristics, which nay affect the embolization process of an aneurysm sac, are changed by the locations of coils for the Partially blocked aneurysms. Blood flow fields are also influenced by the geometry of a parent vessel. In order to suggest the coil locations effective for aneurysm embolization, the blood flow fields of lateral aneurysm models were analyzed for the different coil locations and parent vessel geometries. Three dimensional pulsatile flow fields are analyzed by numerical methods considering non-Newtonian viscosity characteristics of blood. Flow rate into the aneurysm sac (inflow rate) and wall shear stress, which are suspected as flow dynamic factors influencing aneurysm embolization, are also calculated. Inflow rates were smaller and the low wall shear stress zones were larger in the neck blocked models compared to the dome blocked models. Smaller inflow and larger low wall shear stress zones in the distal neck blocked model imply that the distal neck should be the effective coil locations for aneurysm embolization.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.17 no.3
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• pp.216-222
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• 2005

An experimental investigation was executed to determine the capacity degradation due to fin conduction and non-uniform refrigerant distribution in a multi-path evaporator with cross-counter flow. The finned-tube evaporator, which had a three-path and three-depth-row, was tested by controlling inlet quality, exit pressure, and exit superheat for each refrigerant path. The capacity reduction due to superheat unbalance between each path was as much as $25\%$ for non-cutting evaporator, even when the overall evaporator superheat was kept at a target value of $5.6^{\circ}C$. It indicates that the internal heat transfer within the evaporator assembly causes the partial capacity drop. The capacity of cutting-evaporator with respect to non-cutting evaporator was enhanced according to the increment of air flow rate when superheat or superheat unbalance increased.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.7 no.3
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• pp.528-537
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• 1995

Natural convective flow and heat transfer characteristics in a partially opened enclosure fitted with a horizontal divider are investigated numerically. The enclosure is composed of a lower hot and a upper cold horizontal walls and adiabatic vertical walls. A divider is attached perpendicularly to the vertical insulated wall. The governing equations are solved by using the finite element method with Galerkin method. The computations have been carried out by varying the length of divider, the opening size, and the Rayleigh number based on the temperature difference between two horizontal walls and the enclosure height for air(Pr=0.71). As result, when the opening size is fixed, the intensity of the secondary flow is weaken as the length of divider increases. The maximum heat transfer rate over the upper cold wall occurs at a position bounded on the opening. However, when the length of divider is increased considerably, its maximum occurs at the right wall. The stability and frequency of oscillation are affected by the Rayleigh number and length of divider. The Nusselt number is increased with the increase of the opening size and the increase of Rayleigh number.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.2
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• pp.224-232
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• 2000

Four turbulent $k-{\varepsilon}$ models (i.e., standard model, modified models with streamline curvature modification and/or preferential dissipation modification) are applied in order to analyze the turbulent flow of wall-attaching offset jet. For numerical convergence, this paper develops a method of slowly increasing the convective effect induced by skew-velocity in skew-upwind scheme (hereafter called Partial Skewupwind Scheme). Even though the method was simple, it was efficient in view of convergent speed, computer memory storage, programming, etc. The numerical results of all models show good prediction in first order calculations (i.e., reattachment length, mean velocity, pressure), while they show some deviations in ·second order (i.e., kinetic energy and its dissipation rate). Like the previous results obtained by upwind scheme, the streamline curvature modification results in better prediction, while the preferential dissipation modification does not.