• Journal of Chest Surgery
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• 제48권1호
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• pp.59-62
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• 2015

Interventional device closure has emerged as a less invasive alternative to surgery in the management of paravalvular leakage. However, this procedure involves various problems such as a high probability of residual leakage or hemolysis. Here, we report a case of residual paravalvular leakage despite two attempts at interventional closure in a patient with a history of four previous mitral valve replacements. The fifth operation for the primary repair of paravalvular leakage was performed successfully. Careful evaluation before the procedure and specially designed devices are essential for the interventional treatment of paravalvular leakage. Surgery can be performed adequately in the management of paravalvular leakage even in high-risk patients.

• Journal of Chest Surgery
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• 제21권5호
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• pp.899-904
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• 1988

In Behcet syndrome, cardiac involvements are rare and have been reported pericarditis, myocarditis, right heart endocardial fibrosis, right ventricle mural thrombus with pulmonary embolism, active endocarditis, granulomatous endocarditis, conduction disturbance, acute aortic insufficiency, mitral valve prolapse. Our three patients underwent AVR because of aortic insufficiency and ascending aorta enlargement combined with Behcet syndrome. Two patients had mitral regurgitation too. So one underwent MAP and the other underwent MVR concomitantly. One who underwent AVR have been well for 50 months. Another who underwent AVR+MAP and redo AVR due to aortic paravalvular leakage was died of congestive heart failure. The other who underwent AVR+MVR and repeated AVR three times because of aortic paravalvular leakage is in condition of aortic paravalvular leakage. Paravalvular leakage is considered to recur due to progressive dilatation and fragility of aortic root that is the result of pathologic change of Behcet syndrome in it. If Open heart surgery is needed in Behcet`s syndrome during inflammatory reaction is active, postoperative complications such as paravalvular leakage or suture line rupture may be prevented with pre- and postoperative anti-inflammatory management.

• Journal of Chest Surgery
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• 제41권2호
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• pp.268-272
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• 2008

판막주위농양은 판막륜과 주변조직의 감염성 괴사로 인하여 판막을 치환하기 전에 괴사된 조직의 제거와 첩포 재건술이 필요한 경우로 정의되며, 수술사망률과 합병증 및 재발률이 높은 것으로 알려져 있다. 본원에서는 13년전에 기계판막으로 승모판막치환술을 받은 59세 여자 환자에서 외래 추적 관찰중 발견된 판막주위농양에 의한 판막주위누출로 승모판륜재건술과 함께 승모판막치환술을 시행 받았으나, 술후 15병일째 판막주위누출이 재발하여 다시 승모판륜재건술 및 승모판막치환술을 시행 한 경우를 치험하여 보고하며, 환자는 수술후 8개월째 외래 경과관찰중이다.

• Journal of Chest Surgery
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• 제19권4호
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• pp.584-594
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• 1986

Despite the multivariate improvements in tissue treatment, material, and design of prosthetic heart valves in recent years, numerous complications that may lead to valve dysfunction remain a constant threat after valve replacement. Most common indications for prosthetic valve failure are primary valve failure, infective endocarditis, paravalvular leakage, and thromboembolism. From 1977 to 1986, 15 patients underwent reoperation for prosthetic valve failure in 278 cases of valve surgery. The etiology of prosthetic valve failure were primary valve failure in 12 patients [80 %], infective endocarditis in 2 patients [13.3 %], and a paravalvular leakage [6.7 %]. The average durations of implantation were 45.5 months; 53.9 months in primary valve failure, 16 months in infective endocarditis, and 4 months in paravalvular leakage. The rate of valve failure was high under age of 30 [11/15]. Calcifications and collagen disruption of prosthesis were main cause of primary valve failure in macro- & micropathology. Prosthesis used in reoperation were 5 tissue valves and 10 mechanical valves. Operative mortality were 13.3 % [2/15], due to intractable endocarditis and ventricular arrhythmia.

• Journal of Chest Surgery
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• 제29권4호
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• pp.444-448
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• 1996

작은 인공판막주위 누출에 의한 용혈성 빈혈은 인공판막 치환술후올수 있는 합병증중의 하나이다. 경도의 용혈은 대개 기계 판막으로 대동맥 판막 치환술을 시행했을 때 생기 지만, 드물게는 승모판막 치환 술 후에 생 기도 더욱 드물게 조직판막 치환술 후에도 생 긴다 조직판막 치환술후에 용혈성 빈혈은 거의 생기지 않는다. lonescu-Shiley 심낭판막 치환술을 받은 환자에서 용혈성 빈혈은 승모판막에서는 없었고, 대동맥판막 에서 주로 발생하였다고 보고되 어 왔다. 41세 여자환자가 갑자기 진한적색뇨가생겨 본원에 입원하였다. 이 환자는 10년전 승모판막 폐쇄부전증으로 승모판막 치환술(lonescu-Shiley판막 27mm)을 받았던 병 력 이 있다. 심초음파검사상 판막을 통한 경도의 승모판막 폐쇄부전과 함께 판막의 비후가 관찰되었으나 판막주 위를 통해 세어나오는 판막주위 누출의 소견은 관찰할 수 없었다. 말초혈액도말검사상정적혈구성 정색소성 빈혈을 보였다. 혈액 및 요 검사에서 심한 용혈소견이 보였다. 51. Jude Medical 양엽 판막(size 27mm)으로 승모판막 치환술을 시행하였다. 수술시 lonescu-Shiley 판막에 판엽의 석 회화와 뒤틀림 ( istortion)이 있었고, 술자위 치 에서 1시 방향에 직경 5mm의 작은 판막주위 누출이 발견되었으며 이것이 용혈성 빈혈의 원인으로 생각되었다. 승모판 막 재치환술후 용혈소견은 완전히 사라졌다. 저자들은 작은 인공판막주위 누출에 의한 심한 용혈성 빈혈이 발생한 1예를 경험하였기에 문헌고찰 과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제21권4호
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• pp.706-710
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• 1988

Intravascular hemolysis occurs in the majority of patient with mechanical valve prosthesis. The primary cause is mechanical trauma to red cells from turbulent blood flow through the prosthesis. Degree of hemolysis is dependent upon the type, size and material of valve and aggravated by paravalvular leakage. Clinically important hemolytic anemia is required medical management or consideration of reoperation. In severe hemolysis, reoperation is recommended without delay when seems to be renal failure. In this case, postoperative severe mechanical hemolysis was developed immediately after aortic valve replacement with St. Jude medical valve in a 13 year-old male patient. Neither significant paravalvular leakage nor valvular dysfunction was found through redo, but the mechanical valve was strongly suspected the cause of severe hemolysis. The St. Jude Medical valve was changed with Ionescu-Shiley bioprosthesis and any significant clinical problems were not noted through the postoperative course.

• Journal of Chest Surgery
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• 제35권11호
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• pp.822-825
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• 2002

승모판막의 인공판막 재치환술 후 발생하는 판막주위 누출은 드물지만 심각한 합병증이다. 판막주위 누출은 생존률의 증가나 증상호전을 위하여 적극적인 수술적 치료가 필요하다. 그러나 누출부의 단순한 봉합이나 첨포를 이용한 폐쇄는 판륜의 주위조직이 약화된 경우나 결손이 광범위한 경우에는 효과적이지 않다. 이에 저자들은 다크론 판 (Dacron sheet)으로 봉합륜(sewing ring)을 확장한 인공 기계 판막을 이용하여 판륜에 판막을 고정함과 동시에 다크론 판을 좌심방벽에 봉합하여 판막의 고정과 더불어 혈액의 누출을 방지하는 삼차 승모판막 재치환술을 시행하였다. 3례 모두 수술 후 특별한 문제없이 추적 관찰 중이다.

• Journal of Chest Surgery
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• 제20권1호
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• pp.55-69
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• 1987

The result of valve failure with the lonescu-Shiley pericardial xenograft was presented with the review of current knowledge. This study reviewed 557 patients, who underwent total of 683 lonescu-Shiley pericardial valve replacement from 1979 to 1985 at Seoul National University Hospital. There were 357 patients who had mitral valve replacement, 73 with aortic valve and 127 with double valve replacement. There were 35 operative deaths. The survivors were followed at OPD. There were 32 patients who had prosthetic valve failure, whose ages ranged from 11 to 58 years [mean 27.8] and their postop interval was 56 ~ 22 months [range; 6-87] The causes of valve failure are prosthetic valve endocarditis in 14, primary disruption or calcification in 13, paravalvular leakage in 4, and others in 2 patients. Redo valve replacement was done in 12 patients after a mean interval of 50 * 20 months. [range; 6-79 months] Actuarial analysis of late results indicates actuarial freedom from endocarditis at 6 year is 87.9 ~ 6.8%, and actuarial freedom from primary disruption or calcification or paravalvular leakage at 5 year is 84.4 * 2.3%. In this series, however, valve failure due to thrombosis is not included.

• Journal of Chest Surgery
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• 제30권7호
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• pp.719-723
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• 1997

저자들은 대동맥 판막치환술 후 생긴 대동맥 판막 주위 누출과 관련된 대동맥동류의 심실 중격 박리를 경험하였다. 37세 남자 환자가 호흡 곤란의 증가를 주소로 응급실을 통하여 입원하였다. 그는 6년전 대동맥판 폐쇄 부전과 승모판 폐쇄 부전으로 인공 기계 판막(Carbomedic 23mm와 31mm)으로 치환 수술을 받고 정기적으로 추적 검진 중이었다. 진단은 경흉부및 경식도 심초음파로 이루어졌고, 대동맥 조영술로 확인되었다. 폐동맥판 동종이식편(Pulmonary homoyaft)를 사용하여 대동맥 판막 치환술을 다시 시행하였다. 심실중격내의 낭 입구에서 3-0 prolene을 사용하여 심근 내막, 외막과 homograft muscle shoulder를 한꺼번에 연속 봉합하였다. 술후 경과는 양호하여 환자는 수술 후 11일째 퇴원하였다.

• Journal of Chest Surgery
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• 제56권6호
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• pp.435-444
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• 2023

Background: Edwards Intuity is recognized as a relatively contraindicated bioprosthesis for bicuspid aortic valve disease. This study compared the early echocardiographic and clinical outcomes of rapid-deployment aortic valve replacement for bicuspid versus tricuspid aortic valves. Methods: Of 278 patients who underwent rapid-deployment aortic valve replacement using Intuity at Seoul National University Hospital, 252 patients were enrolled after excluding those with pure aortic regurgitation, prosthetic valve failure, endocarditis, and quadricuspid valves. The bicuspid and tricuspid groups included 147 and 105 patients, respectively. Early outcomes and the incidence of paravalvular leak were compared between the groups. A subgroup analysis compared the outcomes for type 0 versus type 1 or 2 bicuspid valves. Results: The bicuspid group had more male and younger patients. Comorbidities, including diabetes mellitus, hypertension, chronic kidney disease, and coronary artery disease, were less prevalent in the bicuspid group. Early echocardiographic evaluations demonstrated that the incidence of ≥mild paravalvular leak did not differ significantly between the groups (5.5% vs. 1.0% in the bicuspid vs. tricuspid groups, p=0.09), and the early clinical outcomes were also comparable between the groups. In the subgroup analysis between type 0 and type 1 or 2 bicuspid valves, the incidence of mild or greater paravalvular leak (2.4% vs. 6.7% in type 0 vs. type 1 or 2, p=0.34) and clinical outcomes were comparable. Conclusion: Rapid-deployment aortic valve replacement for bicuspid aortic valves demonstrated comparable early echocardiographic and clinical outcomes to those for tricuspid aortic valves, and the outcomes were also satisfactory for type 0 bicuspid aortic valves.