• Title/Summary/Keyword: Parametric Study

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Dose-Response Relationship of Avian Influenza Virus Based on Feeding Trials in Humans and Chickens (조류인플루엔자 바이러스의 양-반응 모형)

  • Pak, Son-Il;Lee, Jae-Yong;Jeon, Jong-Min
    • Journal of Veterinary Clinics
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    • v.28 no.1
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    • pp.101-107
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    • 2011
  • This study aimed to determine dose-response (DR) curve of avian influenza (AI) virus to predict the probability of illness or adverse health effects that may result from exposure to a pathogenic microorganism in a quantitative microbial risk assessment. To determine the parametric DR relationship of several strains of AI virus, 7 feeding trial data sets challenging humans (5 sets) and chickens (2 sets) for strains of H3N2 (4 sets), H5N1 (2 sets) and H1N1 (1 set) from the published literatures. Except for one data set (study with intra-tracheal inoculation for data set no. 6), all were obtained from the studies with intranasal inoculation. The data were analyzed using three types of DR model as the basis of heterogeneity in infectivity of AI strains in humans and chickens: exponential, beta-binomial and beta-Poisson. We fitted to the data using maximum likelihood estimation to get the parameter estimates of each model. The alpha and beta values of the beta-Poisson DR model ranged 0.06-0.19 and 1.7-48.8, respectively for H3N2 strain. Corresponding values for H5N1 ranged 0.464-0.563 and 97.3-99.4, respectively. For H1N1 the parameter values were 0.103 and 12.7, respectively. Using the exponential model, r (infectivity parameter) ranged from $1.6{\times}10^{-8}$ to $1.2{\times}10^{-5}$ for H3N2 and from $7.5{\times}10^{-3}$ to $4.0{\times}10^{-2}$ for H5N1, while the value was $1.6{\times}10^{-8}$ for H1N1. The beta-Poisson DR model provided the best fit to five of 7 data sets tested, and the estimated parameter values in betabinomial model were very close to those of beta-Poisson. Our study indicated that beta-binomial or beta-Poisson model could be the choice for DR modeling of AI, even though DR relationship varied depending on the virus strains studied, as indicated in prior studies. Further DR modeling should be conducted to quantify the differences among AI virus strains.

A Theoretical Study on the FRP Retrofit of Existing Circular Bridge Piers for Seismic Performance Enhancement (기존 원형교각의 내진성능 향상을 위한 FRP 보강에 대한 이론적 연구)

  • Kwon Tae-Gyu;Choi Young-Min;Hwang Yoon-Knok;Yoon Soon-Jong
    • Journal of the Korea Concrete Institute
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    • v.16 no.1 s.79
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    • pp.61-69
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    • 2004
  • The bridge piers under service suffered a brittle failure due to the deterioration of lap-spliced longitudinal reinforcement without developing its flexural capacity or ductility. The earthquake induced lateral force results in tension which causes bond-slip failure at the lap-spliced region in circular bridge piers. In this case, such a brittle failure can be controlled by the seismic retrofit using FRP laminated circular tube. The retrofitted piers using FRP laminated circular tube showed significant improvement in seismic performance due to FRP's confinement effect. This paper presents the analytical results on the seismic strengthening effect of circular bridge piers with poor lap-splice details and strengthened with FRP laminated circular tube. FRP's confinement effect is predicted by the classical elasticity solution for the laminated circular tube manufactured with several layers. The FRP laminated circular tube induces the flexural failure instead of a bond-slip failure of the circular reinforced concrete piers under seismic induced lateral forces. To investigate the correctness and effectiveness of analytical solution derived in this study, the analytical results were compared with the experimental data and it was confirmed that the results were correlated well each other, The effects on the confinement of FRP laminated circular tube, such as the number of layers, the fiber orientations, and the mechanical properties, were investigated. From the parametric study, it was found that the number of layers, the fiber orientations, and the major Young's modulus (E11) of the FRP laminated circular tube were the dominant parameters affecting the confinement of reinforced concrete circular bridge piers.

Design and Assessment of Reliquefaction System According to Boil Off Gas Reliquefaction Rate of Liquefied Hydrogen Carrier (액화수소 운반선의 증발가스 재액화 비율에 따른 재액화 시스템의 설계 및 평가)

  • Cho, Wook-Rae;Lee, Hyun-Yong;Ryu, Bo-Rim;Kang, Ho-Keun
    • Journal of Navigation and Port Research
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    • v.44 no.4
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    • pp.283-290
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    • 2020
  • BOG (Boil Off Gas) generation is unavoidable in the liquefied hydrogen carrier, and proper measures are necessary to prevent pressure problems inside the cargo tank. The BOG can be used as propulsion fuel for ships, and the remaining parts used for propulsion must be effectively managed, such as in the form of reliquefying or burning. This study proposes an BOG reliquefaction system optimized for a 160,000 m3 liquefied hydrogen carrier with a hydrogen propulsion system. The system comprises a hydrogen compression and helium refrigerant section, and increases the efficiency by effectively using the cold energy of the BOG discharged from the cargo tank. In this study, the system was evaluated through the exergy efficiency and SEC (Specific Energy Consumption) analysis according to the rate of the reliquefaction of the BOG while the hydrogen BOG with a supply temperature of -220℃ entered the reliquefaction system. As a result, it showed SEC of 4.11 kWh/kgLH2 and exergy efficiency of 60.1% at the rate of reliquefaction of 20%. And the parametric study of the effects of varying the hydrogen compression pressure, inlet temperature of the hydrogen expander, and the feed hydrogen temperature was conducted.

Proposal of Design Method for Landslides Considering Antecedent Rainfall and In-situ Matric Suction (선행강우와 현장 모관흡수력을 고려한 산사태 해석 방법 제안)

  • Kim, Jung-Hwan;Jeong, Sang-Seom;Kim, Yong-Min;Lee, Kwang-Woo
    • Journal of the Korean Geotechnical Society
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    • v.29 no.12
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    • pp.11-24
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    • 2013
  • This study presents a design method for typical rainfall-induced landslide considering in-situ matric suction. Actual landslide data are used to validate the proposed method. The soil-water characteristic curve (SWCC) and unsaturated permeability are experimentally determined to estimate hydraulic properties of testing site. The field measurement of matric suction is carried out to monitor in-situ matric suction in a natural slope subjected to rainfall infiltration, which is incorporated in the landslide analysis. The wetting band depth and safety factor of the slope are assessed to clarify the effect of domestic rainfall pattern. Especially, the effect of antecedent rainfall on the slope stability is investigated and discussed in terms of wetting band depth using parametric study. It is found from the result of this study that proposed design method can consider the characteristic of unsaturated soil and effect of antecedent rainfall. The location of the scarp zone is fairly well predicted by proposed design method. Moreover, heavy rainfall, concentrated in the backward part with time, causes the lowest safety factor of the slope. These results demonstrate that decrease in matric suction due to antecedent rainfall may trigger slope instability. After the antecedent rainfall, additional rainfall may cause the slope failure due to increasing wetting band depth.

Thermodynamic Analysis of the Organic Rankine Cycle as a Waste Heat Recovery System of Marine Diesel Engine (유기 랜킨 사이클을 이용한 선박 주기관 폐열 회수 시스템의 열역학적 분석)

  • Jin, Jung-Kun;Lee, Ho-Ki;Park, Gun-Il;Choi, Jae-Woong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.7
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    • pp.711-719
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    • 2012
  • A thermodynamic analysis and a feasibility study on the organic Rankine cycle (ORC) as a waste heat recovery system for a marine diesel engine were carried out. The ORC and its combined cycle with the engine were simulated, and its performance was estimated theoretically using R245fa. A parametric study on the performance of the ORC system was carried out under different temperature conditions of the heat transfer loop and specification of the heat exchanger. According to the thermodynamic analysis, ~10% of the thermal efficiency of the cycle was able to be realized with the low temperature heat source below $250^{\circ}C$. The electric power output of the ORC was estimated to be about 4% of the mechanical power output of the engine, considering additional pumps for cooling water and circulation of the heat transfer medium. According to the present study, the electric power generated by the ORC is about 59%-69% of the required power, and it is possible to reduce the fuel consumption under normal seagoing conditions.

Flange Local Buckling(FLB) for Flexural Strength of Plate Girders with High Performance Steel(HSB 800) (고성능 강재(HSB 800)를 적용한 플레이트 거더의 휨강도에 대한 플랜지 국부좌굴)

  • Kim, Jeong Hun;Kim, Kyoung Yul;Lee, Jeong Hwa;Kim, Kyung Sik;Kang, Young Jong
    • Journal of Korean Society of Steel Construction
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    • v.26 no.2
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    • pp.91-103
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    • 2014
  • High performance steel for bridges(HSB 800) with a minimum tensile stress of 800MPa was recently developed. However, the study for local buckling behavior of plate girders considering interactive effects of flanges and webs is still insufficient. In this study, the flange local buckling(FLB) strength of plate girders with HSB 800 was evaluated by nonlinear finite element analysis. The flanges and webs of plate girders having I-section were modeled as 3D shell elements in the nonlinear analysis. Initial imperfection and residual stress were imposed on the plate girder. The high performance steel was modeled as a multi-linear material. Thus, parametric study of compression flanges with a compact, noncompact and slender web was performed. The flange local buckling behavior of plate girders was analyzed, and the nonlinear analysis results were compared with the nominal flexural strength of both AASHTO LRFD(2012) and KHBDC LSD(2012) codes.

Evaluation of the Stability of Quay Wall under the Earthquake and Tsunami (지진 및 지진해일파 작용하의 해안안벽의 안정성평가)

  • Lee, Kwang-Ho;Ha, Sun-Wook;Lee, Kui-Seop;Kim, Do-Sam;Kim, Tae-Hyung
    • Journal of the Korean Geotechnical Society
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    • v.27 no.3
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    • pp.41-54
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    • 2011
  • The present study analyzes the stability of waterfront quay wall under the combined action of earthquake and tsunami. Adopting the limit equilibrium method, the stability of waterfront quay wall is checked for both the sliding and overturning. Forces due to tsunami are compared with the proposed formula and the 3-D one-field Model for immiscible TWO-Phase flows (TWOPM-3D). Variations of the stability of wall are also proposed by the parametric study including tsunami water height, horizontal seismic acceleration coefficient, internal friction angle of soil, friction angle between the wall and the soil and the pore water pressure ratio. The present study about the stability of wall is also compared with the case when earthquake and tsunami are not considered. As a result, the result of numerical analysis about the tsunami force is similar to that of proposed formula. When earthquake and tsunami are simultaneously considered, the stability of wall in passive case significantly decreases and tsunami forces in active case are affected as a resistance force on the wall and so the stability of wall increases.

Utilization of Induced Polarization and Electrical Resistivity for Identifying Rock Condition (유도분극 전하 충전성과 전기비저항을 활용한 암반 상태 파악 가능성 연구)

  • Park, Jinho;Ryu, Jinwoo;Jung, Jeehee;Lee, In-Mo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.3
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    • pp.493-502
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    • 2016
  • This study examines how rock condition affects the variation of the chargeability and electrical resistivity of the rock. In the theoretical study, the relationship correlating chargeability with the variables affecting it is derived. A parametric study utilizing the derived relationship reveals that the size of narrow pores ($r_1$) is the most influential factor on chargeability, and the salinity of pore water ($C_0$) is the second. In the laboratory experiments, small scale rock fracturing zone is modelled using sand stone. Chargeability and resistivity are measured by changing the size of the joint aperture, the location of fractured zone and the existence of clay gouge and/or clay layer which shows lower chargeability than the sand stone layer in the multi-layered ground. Test results show that chargeability is controlled not by the rock fracturing condition but by the size of narrow pore ($r_1$) where each line of current flow passes through. Also, the chargeability decreases with increase of the pore water salinity ($C_0$). In conclusion, the ground condition can be identified more efficiently by measuring the induced polarization along with the electrical resistivity; identifying the existence of sea water, the layered ground and/or the fractured rock becomes more reliable.

Evaluation on Bending Moment of Bridge Approach Slabs under Vehicle Load Considering Soil Settlement (지반침하를 고려한 교량 접속판의 차량하중에 의한 휨모멘트 평가)

  • Back, Sung-Yong;Kim, Jung-Gang;Cho, Baik-Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.11
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    • pp.5939-5946
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    • 2013
  • The bridge approach slabs (BAS) to provide a transitional roadway between a roadway pavement and a bridge structure have not performed adequately due to various factors. The current Korean Roadway Design Guidelines treat the BAS as a simply supported beam with 70% of the span length and do not consider settlement and void development underneath the slab. To investigate the effect of soil settlements on the bending moment of BAS, a beam on elastic support (BAS-ES) was used in the present study. The parameters used in this study were span length, washout length, washout location, and soil modulus. It was shown from the parametric study that washout regions closer to the midspan exhibit maximum moment in the slab. Since voids under the BAS have typically been observed to be closer to bridge abutments, the springs from the abutment were removed to simulate settlement and void development in the model. The design moments based on AASHTO LRFD Bridge Design Specifications were compared to those of Korean Standard Specifications for Highway Bridge and Design Trucks for Highway Bridges. Even if the design moment from BAS-ES was used to incorporate the effect of the potential washout, significant savings could still be achieved compared to the current BAS design.

Behavior of Composite Structure by Nonlinearity of Steel - concrete Interface (I) -Parametric Study for Nonlinear Model of Interface- (강·콘크리트 경계면의 비선형성에 따른 합성구조체 거동(I) -비선형 경계면 모델에 따른 매개변수 연구-)

  • Jeong, Youn Ju;Jung, Kwang Hoe;Kim, Byung Suk
    • Journal of Korean Society of Steel Construction
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    • v.15 no.5 s.66
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    • pp.499-507
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    • 2003
  • As the load is increased on the steel-concrete composite structure, its interface begins to show nonlinear behavior due to the reduction of interaction, micro-crack, slip and separation, and it causes slip-softening, Therefore, it is essential to consider the partial-interaction analysis technique. Until now, however, full-interaction or, in some instances, the linear-elastic model, which are insufficient to simulate accurate behavior, are assumed in the analysis of composite structure since the analysis method and nonlinear model for interface are very difficult and complicated. Therefore, the design of composite structure is followed by the experimental method which is inefficient-because a number of tests have to be carried out according to the design environments. In this study, we carried out the nonlinear analysis according to various interface nonlinear models by interaction magnitude, and analyzed more accurate structural behavior and performance by maximum tangential traction and slip-softening at the interface. As a result of this study. we were able to prove that the nonlinear model of interface more exactly represents behavior after yielding, such as ultimate load: that initial tangential stiffness of interface has a significant effect on the yielding load of structural members or part: and that the maximum tangential traction and slip-softening mainly effects structural yielding and ultimate load. Therefore, the structural performance of composite structure is highly dependent on the steel-concrete interface or interaction, which may result in initial tangential stiffness, maximum tangential traction and slip-softening in nonlinear model.