• Title/Summary/Keyword: Parameter Management

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Estimation of Human Carcinogenic Potency (HCP) of Carcinogens in Risk Assessment and Management. (위해성 평가 및 관리에 있어서 발암물질의 인체발암능력 평가)

  • 이병무;김대영;김세기;김근종
    • Environmental Mutagens and Carcinogens
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    • v.19 no.1
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    • pp.39-45
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    • 1999
  • Human Carcinogenic Potency (HCP) can be estimated based on human daily exposure dose to carcinogen (Dh), body weight (Wh), 10% tumorigenic dose (TD10), and slope factor at TD10 (Q10) from 2-yr bioassay data. This approach is more relevant to humans generally exposed to low doses of carcinogens and can reduce more of extrapolation errors from high dose in animal experiments to low dose in humans than HERP (human exposure dose/rodent potency dose) proposed by Ames et al. (Science, 236, 271-280, 1987). TD50 and HERP have been routinely used to compare rodent carcinogenic potency and human carcinogenic potency, but those approaches have had limitations in extrapolation of high dose to low dose in humans. The advantages of HCP are to estimate human exposure dose (Dh) by human monitoring instead of environmental monitoring, to consider slope factor (Q10) which reflects the tendency of curve at low dose, and to use TD10 which represents much lower dose thant TD50 or HERP. HCP will be a useful parameter for the estimation of human carcinogenic potency in risk assessment and management of carcinogens.

New Measurement Technique of Expiratory Air Flow Rate Using Miniatured Air Chamber (소형 공기챔버를 센서소자로 사용하는 새로운 호식기류 계측기술)

  • Kim, Kyung-Ah;Lee, Jae-Hun;Kim, Goon-Jin;Lee, Tae-Soo;Cha, Eun-Jong
    • Journal of Sensor Science and Technology
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    • v.13 no.2
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    • pp.79-84
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    • 2004
  • Asthma is one of the important respiratory diseases requiring home self care usually performed by commercialized peak expiratory flow meter (PEFM). However, this simple device can measure only single parameter, PEF, due to its purely mechanical principle, significantly limiting desease management quality. The present study introduced a new expiratory flow measurement technique by miniatured air expansion chamber easily installed within PEFM. Continuous pressure signal obtained from the chamber demonstrated an accurate quadratic relationship with flow. The volume measurement error was $<{\pm}1%$ well within the American Thoracic Society (ATS) criteria of 3%. Important spirometric parameters of FVC, PEF, and FEF25-75% were all accurately estimated with correlation coefficients > 0.95. The present technique obtains continuous expiratory air flow signal, making possible and convenient to perform spirometric test at home. Electronic interface capability would be also useful for remote asthma management.

Determination of Proper Probability Distribution for Groundwater Monitoring Stations in Jeju Island (제주도 지하수위 관측지점별 적정 확률분포형의 결정)

  • Chung, Il-Moon;Nam, Woosung;Kim, Min Gyu;Choi, Gian;Kim, Gee-Pyo;Park, Yun-Seok
    • Journal of Soil and Groundwater Environment
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    • v.23 no.1
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    • pp.41-53
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    • 2018
  • Comprehensive statistical analysis for the 127 groundwater monitoring stations in Jeju Island during 2005~2015 was carried out for the re-establishment of management groundwater level. Three probability distribution functions such as normal distibution, GEV (General Extreme Value) distribution, and Gumbel distribution were applied and the maximum likelihood method was used for parameter estimation of each distribution. AIC (Akaike information criterion) was calculated based on the estimated parameters to determine the proper probability distribution for all 127 stations. The results showed that normal distribution and Gumble distribution were found in 11 stations. Whereas GEV distribution were found in 105 stations, which covered most of groundwater monitoring stations. Therefore, confidence levels should be established in accord with the proper probability distribution when groundwater level management is determined.

Difficult Intubation in Patients Undergone Oromaxillary Surgery: Retrospective Study (전신마취를 시행한 구강외과 환자에서 어려운 기관내삽관: 후향적 연구)

  • Kwon, O-Seon;Kim, Cheul-Hong
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.8 no.2
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    • pp.118-121
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    • 2008
  • Background: This retrospective study aims to describe the airway management and to search predictive parameter for difficult intubation in 700 patients undergoing oromaxillary surgery. Methods: The medical records of 700 patients undergone oromaxillary surgery were reviewed for airway management during perioperative period. The cases of difficult intubation were selected and those radiologic findings were reviewed. The mandibular depth (MD), mandibular length (ML), thyromental distance (TMD) were measured. Results: In 41 cases difficult intubation were recorded in anesthetic record. The grade of Cormack and Lehane was III in 36 patients and IV in 5 cases. The MD of difficult intubation cases was $4.2{\pm}3.2\;cm$. The ML of difficult intubation cases was $10.1{\pm}3.8\;cm$. The TMD of difficult intubation cases was $5.9{\pm}4.3\;cm$. Under the fiberoptic guided awake intubation was undertaken in 75 patient. In none of the cases was failed nasotracheal intubation. Conclusions: The patients undergoing oromaxillar surgery have a potentially difficult airway but, if managed properly during perioperative preiod, morbidity and mortality can be reduced or avoided. The radiologic findings were poor predict for difficult intubation. The fiberoptic guided awake intubation is a safe alternative to direct laryngoscopic intubation.

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Support vector machines with optimal instance selection: An application to bankruptcy prediction

  • Ahn Hyun-Chul;Kim Kyoung-Jae;Han In-Goo
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 2006.06a
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    • pp.167-175
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    • 2006
  • Building accurate corporate bankruptcy prediction models has been one of the most important research issues in finance. Recently, support vector machines (SVMs) are popularly applied to bankruptcy prediction because of its many strong points. However, in order to use SVM, a modeler should determine several factors by heuristics, which hinders from obtaining accurate prediction results by using SVM. As a result, some researchers have tried to optimize these factors, especially the feature subset and kernel parameters of SVM But, there have been no studies that have attempted to determine appropriate instance subset of SVM, although it may improve the performance by eliminating distorted cases. Thus in the study, we propose the simultaneous optimization of the instance selection as well as the parameters of a kernel function of SVM by using genetic algorithms (GAs). Experimental results show that our model outperforms not only conventional SVM, but also prior approaches for optimizing SVM.

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An Improved Task Scheduling Algorithm for Efficient Dynamic Power Management in Real-Time Systems (실시간 시스템에서 효율적인 동적 전력 관리를 위한 태스크 스케줄링 알고리듬에 관한 연구)

  • Lee Won-Gyu;Hwang Sun-Young
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.31 no.4A
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    • pp.393-401
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    • 2006
  • Energy consumption is an important design parameter for battery-operated embedded systems. Dynamic power management is one of the most well-known low-power design techniques. This paper proposes an online realtime scheduling algorithm, which we call energy-aware realtime scheduling using slack stealing (EARSS). The proposed algorithm gives the highest priority to the task with the largest degree of device overlap when the slack time exists. Scheduling result enables an efficient power management by reducing the number of state transitions. Experimental results show that the proposed algorithm can save the energy by 23% on average compared to the DPM-enabled system scheduled by the EDF algorithm.

Influencing factors and prediction of carbon dioxide emissions using factor analysis and optimized least squares support vector machine

  • Wei, Siwei;Wang, Ting;Li, Yanbin
    • Environmental Engineering Research
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    • v.22 no.2
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    • pp.175-185
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    • 2017
  • As the energy and environmental problems are increasingly severe, researches about carbon dioxide emissions has aroused widespread concern. The accurate prediction of carbon dioxide emissions is essential for carbon emissions controlling. In this paper, we analyze the relationship between carbon dioxide emissions and influencing factors in a comprehensive way through correlation analysis and regression analysis, achieving the effective screening of key factors from 16 preliminary selected factors including GDP, total population, total energy consumption, power generation, steel production coal consumption, private owned automobile quantity, etc. Then fruit fly algorithm is used to optimize the parameters of least squares support vector machine. And the optimized model is used for prediction, overcoming the blindness of parameter selection in least squares support vector machine and maximizing the training speed and global searching ability accordingly. The results show that the prediction accuracy of carbon dioxide emissions is improved effectively. Besides, we conclude economic and environmental policy implications on the basis of analysis and calculation.

Analysis of Factors for Private Universities Educational Restitution Rate using Data Mining : Focusing on the Panel Fixed Effect Model and Non-parametric Regression Estimation (데이터 마이닝을 활용한 사립대학 교육비 환원요인 분석 : 패널 고정효과모형과 비모수회귀추정을 중심으로)

  • Chae, Dong Woo;Lee, Mun-Bum;Jung, Kun-Oh
    • Journal of Information Technology Applications and Management
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    • v.27 no.6
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    • pp.153-170
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    • 2020
  • The Educational Restitution Rate is an important parameter that determines the quality of university education. This paper analyzed data from 148 private universities over the 10 years from 2009 to 2018 using data mining techniques in Korea. A significant causal relationship is detected in the fixed effect model as a result of the panel estimation. And the scale of faculty expansion and fund management, which are the university evaluation indicators, and the size of basic funds, respectively, have a positive effect on the ERR, which is within the confidence interval. In the analysis, the more private universities improve the tuition dependence rate, the more decisively positive affecting ERR. As a result of nonparametric regression estimation, when the faculty expansion ratio is reinforced, the effect of economies of scale is detected in some sections, the improvement of the tuition dependence rate, and the result value is generated through the improvement that results are derived at a certain point in time. We hope that the university based on this study can be a basic Indicators for the diagnosis of basic competencies and policy of student-centered education.

Aerosol Deposition Nozzle Design for Uniform Flow Rate: Divergence Angle and Nozzle Length

  • Kim, Jae Young;Kim, Young Jin;Jeon, Jeong Eun;Jeon, Jun Woo;Choi, Beom Soo;Choi, Jeong Won;Hong, Sang Jeen
    • Journal of the Semiconductor & Display Technology
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    • v.21 no.2
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    • pp.38-44
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    • 2022
  • Plasma density in semiconductor fabrication equipment becomes higher to achieve the improved the throughput of the process, but the increase of surface corrosion of the ceramic coated chamber wall has been observed by the increased plasma density. Plasma chamber wall coating with aerosol deposition prefer to be firm and uniform to prevent the potential creation of particle inside the chamber from the deformation of the coating materials, and the aerosol discharge nozzle is a good control factor for the deposited coating condition. In this paper, we investigated the design of the nozzle of the aerosol deposition to form a high-quality coating film. Computational fluid dynamics (CFD) study was employed to minimize boundary layer effect and shock wave. The degree of expansion, and design of simulation approach was applied to found out the relationship between the divergence angle and nozzle length as the key parameter for the nozzle design. We found that the trade-off tendency between divergence angle and nozzle length through simulation and quantitative analysis, and present the direction of nozzle design that can improve the uniformity of chamber wall coating.

A Study on the Establishment of Odor Management System in Gangwon-do Traditional Market

  • Min-Jae JUNG;Kwang-Yeol YOON;Sang-Rul KIM;Su-Hye KIM
    • Journal of Wellbeing Management and Applied Psychology
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    • v.6 no.2
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    • pp.27-31
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    • 2023
  • Purpose: Establishment of a real-time monitoring system for odor control in traditional markets in Gangwon-do and a system for linking prevention facilities. Research design, data and methodology: Build server and system logic based on data through real-time monitoring device (sensor-based). A temporary data generation program for deep learning is developed to develop a model for odor data. Results: A REST API was developed for using the model prediction service, and a test was performed to find an algorithm with high prediction probability and parameter values optimized for learning. In the deep learning algorithm for AI modeling development, Pandas was used for data analysis and processing, and TensorFlow V2 (keras) was used as the deep learning library. The activation function was swish, the performance of the model was optimized for Adam, the performance was measured with MSE, the model method was Functional API, and the model storage format was Sequential API (LSTM)/HDF5. Conclusions: The developed system has the potential to effectively monitor and manage odors in traditional markets. By utilizing real-time data, the system can provide timely alerts and facilitate preventive measures to control and mitigate odors. The AI modeling component enhances the system's predictive capabilities, allowing for proactive odor management.