• 생물정신의학
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• 제19권2호
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• pp.84-90
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• 2012

Objectives : The purpose of this study was to examine the changes in metabolic parameters and Positive and Negative Syndrome Scale (PANSS) scores of patients previously treated with atypical antipsychotic drugs other than paliperidone, after 8 weeks of treatment with paliperidone. Methods : Changes in body weight, body mass index, leptin, lipid levels, fasting glucose, and PANSS scores of patients who switched from other atypical antipsychotic drugs to paliperidone were measured after 8 weeks of treatment with paliperidone. We compared these results with those of patients who had not been treated with antipsychotic drugs for at least 2 weeks prior to treatment with paliperidone (antipsychotic drug-free patients). Results : The antipsychotic drug-free group (n = 9) did not show significant changes in metabolic parameters, but showed a significant improvement in total and subscale scores of PANSS. In the group that switched from other atypical antipsychotic drugs to paliperidone (n = 13), body weight, body mass index and fasting glucose level significantly increased, while total and subscale scores of PANSS significantly improved. Conclusions : Paliperidone treatment will benefit patients with schizophrenia who have been antipsychotic drug-free or who have had difficulty with other atypical antipsychotic drugs, with regard to their psychopathological state. However, if patients have been treated with other atypical antipsychotic drugs before switching to paliperidone, they could gain body weight or their fasting glucose level could increase over a short period because of a change in receptor number and sensitivity caused by the previously prescribed antipsychotic drugs, and hence, paliperidone should be prescribed with caution for these patients.

• Journal of Chest Surgery
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• 제22권2호
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• pp.191-201
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• 1989

Nowadays, in spite of the remarkable development of the results of open heart surgery, the incidence of postoperative acute renal failure [ARF] has been increased due to the expansion of the candidates and prolonged operation time for complicated cases. It is also well known that ARF after open heart surgery, if once occurred, is a critical complication, therefore early diagnosis and treatment about it are very important for prognosis. Recently a low molecular weight [2 * microglobulin [[2* MG]has been used as a indicator of renal function. Because of the properties of [2 * MG, serum concentration of it is increased in glomerular dysfunction and urine excretion of it is increased in tubular dysfunction. Author studied about the perioperative changes of serum [2* MG and BUN concentration in 25 children and 30 adults for evaluation of significances of [2* MG as a parameter of postoperative renal function in open heart surgery, and the results were obtained as follows. l. In open heart surgery, the serum [2* MG concentration was elevated postoperatively in the all cases from the first postoperative day. 2. There were a significant correlation between the preoperative BUN and [2* MG concentration [P< 0.01]. The correlation factor[r] in child group was 0.8512, and in adults 0.8636. 3. The maximum level of serum [2* MG in the both child and adult groups were noticed in 4th postoperative day as 2.61*0.80mg/ 1 in child group and 3.39*1.47 mg/ 4 in adult group, and there was a significant difference between the two groups statistically[P < 0.05]. 4. The pattern of changes of serum concentration of [2* MG with time was very similar with the changes of BUN, but in a case of ARF [expired with it] the changes of [2* MG was more remarkable. 5. There was a significant differences in the maximum level of [2* MG between the 2 group according to the ECC time [groups of below and above 60 minutes] [P< 0.01].

• 생물환경조절학회지
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• 제32권3호
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• pp.205-209
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• 2023

기계적 자극은 식물체의 형태적 변화를 유도하는 것으로 알려져 있다. 본 연구에서는 기계적 자극을 적용한 토마토의 육묘기 동안의 생육 변화를 확인하기 위해 수행되었다. 브러싱 처리가 기계적 자극으로 이용되었으며, 아크릴이 부착된 이송장치를 이용하여 2시간 간격으로 파종 후 10일 이후부터 처리를 진행하였다. 브러싱 처리 동안 생육 변화를 확인하기 위해 3일 간격으로 생육을 조사하였다. 초장과 엽면적은 브러싱 처리에서 대조구에 비해 감소하는 결과를 보였으며 지상부의 생체중과 건물중은 대조구와 유사한 값을 보였다. 총 근장과 지하부 표면적은 브러싱 처리에서 대조구에 비해 증가하였으며, 지하부 부피는 대조구와 브러싱 처리가 유사한 값을 보였다. 결론적으로 토마토 공정묘에 브러싱 처리는 지상부의 생육 감소를 유도하였으며 지하부의 형태적 발달을 증가시키는 것으로 판단된다.

• Korean Journal of Radiology
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• 제22권3호
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• pp.435-441
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• 2021

Objective: To evaluate the usefulness of the ventricular volume percentage quantified using three-dimensional (3D) brain computed tomography (CT) data for interpreting serial changes in hydrocephalus. Materials and Methods: Intracranial and ventricular volumes were quantified using the semiautomatic 3D threshold-based segmentation approach for 113 brain CT examinations (age at brain CT examination ≤ 18 years) in 38 patients with hydrocephalus. Changes in ventricular volume percentage were calculated using 75 serial brain CT pairs (time interval 173.6 ± 234.9 days) and compared with the conventional assessment of changes in hydrocephalus (increased, unchanged, or decreased). A cut-off value for the diagnosis of no change in hydrocephalus was calculated using receiver operating characteristic curve analysis. The reproducibility of the volumetric measurements was assessed using the intraclass correlation coefficient on a subset of 20 brain CT examinations. Results: Mean intracranial volume, ventricular volume, and ventricular volume percentage were 1284.6 ± 297.1 cm³, 249.0 ± 150.8 cm³, and 19.9 ± 12.8%, respectively. The volumetric measurements were highly reproducible (intraclass correlation coefficient = 1.0). Serial changes (0.8 ± 0.6%) in ventricular volume percentage in the unchanged group (n = 28) were significantly smaller than those in the increased and decreased groups (6.8 ± 4.3% and 5.6 ± 4.2%, respectively; p = 0.001 and p < 0.001, respectively; n = 11 and n = 36, respectively). The ventricular volume percentage was an excellent parameter for evaluating the degree of hydrocephalus (area under the receiver operating characteristic curve = 0.975; 95% confidence interval, 0.948-1.000; p < 0.001). With a cut-off value of 2.4%, the diagnosis of unchanged hydrocephalus could be made with 83.0% sensitivity and 100.0% specificity. Conclusion: The ventricular volume percentage quantified using 3D brain CT data is useful for interpreting serial changes in hydrocephalus.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2009년도 추계학술대회 논문집
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• pp.130-136
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• 2009

The goal of this paper is to develop a standard side mirror geometry that will perform well across multiple vehicles. One of the important performance attributes of a side mirror is the amount of wind noise generated under the flow conditions on a car. PowerFLOW can be used for Computer Aided Testing of the aeroacoustics performance of a design in addition to directing design modifications based on a detailed analysis of the flow structures responsible for the noise generation. Alternatively, a Design of Experiment (DOE) approach is useful to explore the design space without any a-priori assumptions of the effects of design parameter changes. Some general design guidelines regarding the significant mirror geometry factors will be determined which may help to reduce vehicle development time and cost in the future. The results of this research will also allow us to estimate the trade-off between cost saving and performance optimum related to using a standard mirror shape for different vehicles.

• Journal of the Korean Data and Information Science Society
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• 제7권1호
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• pp.47-57
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• 1996

일정스트레스 가속수명시험에서 제품의 수명이 대수정규분포를 따르고 위치모수와 척도모수 모두가 스트레스의 영향을 받는다고 하자. 설계 스트레스 조건에서 대수정규분포의 백분위수의 최우추정량의 점근분산이 최소가 되는 낮은 수준의 최적의 스트레스의 양과 최적의 표본할당비율을 모수의 여러 가지 경우에 대해서 연구한다.

• 임산에너지
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• 제18권2호
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• pp.84-91
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• 1999

The objective of this study was to present creep and the effects of mechano-sorptive deflection of drift pin moment resisting joint between LVL members under changing relative humidity (RH) conditions. The LVL members with steel gusset were jointed by a square pattern of eight injected drift pin. Three diameter drift pins were used to test specimens (6mm, 10mm, and 16mm). The creep test was conducted under two constant loading conditions : one at 30 kgf(840 kgf-cm) and the other at 60 kgf(1680 kgf-cm). The experiment was conducted in an open shed outside. (1)The total rotation creep model of moment resisting joing can be expressed as the sum of the creep of controlled environment (3-parameter model), dimensional change and mechano-sorptive deflection resulting from the variable environment. (2)Mechanosorptive rotation creep is recoverable as moisture content increases during adsorption. Least squares method for linear regression analysis was performed using mechano-sorptive rotation creep as the dependent variable and moisture content as the independent variable. The slope of low moment specimens are compared with those of high moment. This means that low moment condition is more easily affected by changes in humidity than high moment conditions. (3)Although creep deflection is higher for small diameter drift pin than for large diameter drift pin, the shape of creep deflection curves for all specimens is similar.

• 한국정밀공학회지
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• 제17권10호
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• pp.69-76
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• 2000

Lots of semi-active control devices have been developed in recent years because they have the best features of passive and active system. Especially, controllable magneto-rheological(MR) fluid devices have received significant attention in these area of research. The MR fluid is the material that reversibly changes from a free-flowing, linear viscous fluid to a semisolid with a controllable yield strength in milliseconds when exposed to a magnetic field. If the magnetic field is induced by moving a permanent magnet instead of applying current to a solenoid, it is possible to design a MR damper consuming low power because the power consumption is reduced at steady state. This paper proposes valve mode MR damper using permanent magnetic circuit that has wide range of operation with low power consumption, a design parameter is adopted. The magnetic circuit, material of choke and choke type are selected experimentally with the design parameter. The behaviors of the damper are examined and torque tracking control using PID feedback controller is performed for step, ramp and sinusoidal trajectiories.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2002년도 Proceedings of International Symposium on Remote Sensing
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• pp.766-771
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• 2002

Automatic change detection based on the vector-to-raster comparison is hard especially in high-resolution image. This paper proposes a method to designate roads in high-resolution image in sequential manner using the information from vector map in which Hough transform is used for reliability. By its linearity, the road of urban areas in a vector map can be easily parameterized. Following some pre-processing to remove undesirable objects, we obtain the edge map of raster image. Then the edge map is transformed to a parameter space to find the selected road from vector map. The comparison is done in the parameter space to find the best matching. The set of parameters of a road from vector map is treated as the constraints to do matching. After designating the road, we may overlay it on the raster image for precise monitoring. The results can be used for detection of changes in road object in a semi-automatic fashion.

• 제어로봇시스템학회논문지
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• 제6권12호
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• pp.1079-1085
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• 2000

In this paper, we propose a method of cooperative control (T-cell modeling) and selection of group behavior strategy (B-cell modeling) based on immune system in distributed autonomous robotic system (DARS). An immune system is the living bodys self-protection and self-maintenance system. these features can be applied to decision making of the optimal swarm behavior in a dynamically changing environment. For applying immune system to DARS, a robot is regarded as a B-cell, each environmental condition as an antigen, a behavior strategy as an antibody, and control parameter as a T-cell, respectively. When the environmental condition (antigen) changes, a robot selects an appropriate behavior strategy (antibody). And its behavior strategy is stimulated and suppressed by other robots using communication (immune network). Finally, much stimulated strategy is adopted as a swarm behavior strategy. This control scheme is based on clonal selection and immune network hypothesis, and it is used for decision making of the optimal swarm strategy. Adaptation ability of the robot is enhanced by adding T-cell model as a control parameter in dynamic environments.