• Title/Summary/Keyword: Parallel synthesis

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Simulation of the Effect of Protein Quality at the Different Protein Intake Level on Protein Metabolism (각기 다른 단백질섭취 수준에서 본 식이단백질의 질이 단백질대사에 미치는 영향 -Simulation Model을 이용하여-)

  • 이옥희
    • Journal of Nutrition and Health
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    • v.26 no.9
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    • pp.1033-1048
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    • 1993
  • This study was designed to describe the effect of the protein quality at different intake level of protein on the protein metabolism in the whole body of growing pigs with a simulation model. Varying to the protein level in feeds, four simulations were conducted. The feed protein level, represented as proportions of digestible protein to the metabolic energy (DP/ME, g/MJ), were 6-8, 11-13, 17-19, and 23-25 DP/ME, respectively. Two protein quality and six weeks of growth time were used at each simulation. The objective function for the simulations was protein deposition in the whole body, which was calculated from the experimental results. The parameters in the simulation were determined by the parameter estimation technique. The results obtained from the simulation were as follows: The protein synthesis and breakdown rates(g/day) in the whole body was increased with the increase of protein quality only at lower or required level of protein intake. They showed a parallel behavior in the course of growth, irrespective of quality and level of feed protein intake. The simulated protein deposition and protein synthesis showed a linear relationship between them at different protein quality and level. The affinity parameter showed a linear relationship between them at different protein quality and level. The affinity parameter showed that arginine, tryptophan and isoleucine were more efficient in the stimulation ofbody protein synthesis. Lysine and phenylalanine+tyrosine were less efficient. The oxidation parameter showed that histidine, pheyalanine+tyrosine were less efficient. The oxidation parameter showed that histidine, phenyalanine+tyrosine, and methionine+cystine were oxidized in larger magnitude than lysine and threonine. The oxidation parameter of most amino acids increased with the increase of protein intake beyond the requirement level, but not any more at highest protein intake level. Finally it was found that the improvement of feed protein quality at the lower or required level of protein intake increase protein deposition through a parallel increase of protein synthesis and breakdown.

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Synthesis of Japanese Encephalitis Virus in Porcine Kidney Stable Cells Observed by Fluorescent Antibody Technique and Autoradiography

  • Lee, Chong-Hoon;Fukai, Konosuke
    • The Journal of the Korean Society for Microbiology
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    • v.3 no.1
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    • pp.51-65
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    • 1968
  • The site of the synthesis of Japanese encephalitis virus(JEV) in the actinomycin-treated and infecter PS Y15 cells(a porcine kidney stable cell line) was observed by the immunofluorescent antibody technique, acridine orange staining, and the autoradiographic analysis. In the parallel studies by immunofluorescent technique and acridine orange staining it the infected cells, Viral protein(as an antigen) and viral RNA were detected at the same site of cytoplasm. In the autoradiographic analysis, the cytoplasmic labeling of $^3H$-uridine was due to the synthesis of JEV-RNA, while the nucleolus and nucleus were not involved. In the autoradiographic studies on the secton of infected cells, the $^3H$-uridine was frequently incorporated around the cytoplasmic vacuoles. This localization of labeling agreed with the site of acridine orange positive granules. The results suggest that the syntheses of the viral RNA and viral protein occurred in the similar site of cytoplasm of the infected cells, and also the virus particles seem to be assembled in the sites of the viral RNA and protein syntheses.

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Solid-Phase Synthesis of Unfunctionalized Arenes Via the Traceless Cleavage of Sulfonate Linkers

  • Kim, Chul-Bae;Cho, Chul-Hee;Jo, Min-Jy;Park, Kwang-Yong
    • Bulletin of the Korean Chemical Society
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    • v.32 no.10
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    • pp.3655-3659
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    • 2011
  • The hydrogenolysis of polymer-bound arenesulfonates by 2-propylmagnesium chloride was performed through reductive cleavage of the C-S bond in the presence of a nickel catalyst. The reaction underwent in the highest efficiency by adding 15 equiv of the nucleophile in two additions with $dppfNiCl_2$ in THF. Various unfunctionalized naphthalene, biphenyl, and stilbene derivatives were produced in good yields by the traceless sulfonate linker system at room temperature.

Low-Power and Low-Hardware Bit-Parallel Polynomial Basis Systolic Multiplier over GF(2m) for Irreducible Polynomials

  • Mathe, Sudha Ellison;Boppana, Lakshmi
    • ETRI Journal
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    • v.39 no.4
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    • pp.570-581
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    • 2017
  • Multiplication in finite fields is used in many applications, especially in cryptography. It is a basic and the most computationally intensive operation from among all such operations. Several systolic multipliers are proposed in the literature that offer low hardware complexity or high speed. In this paper, a bit-parallel polynomial basis systolic multiplier for generic irreducible polynomials is proposed based on a modified interleaved multiplication method. The hardware complexity and delay of the proposed multiplier are estimated, and a comparison with the corresponding multipliers available in the literature is presented. Of the corresponding multipliers, the proposed multiplier achieves a reduction in the hardware complexity of up to 20% when compared to the best multiplier for m = 163. The synthesis results of application-specific integrated circuit and field-programmable gate array implementations of the proposed multiplier are also presented. From the synthesis results, it is inferred that the proposed multiplier achieves low power consumption and low area complexitywhen compared to the best of the corresponding multipliers.

Changes in the RNA and Protein Synthesis at the Pre- and Post fertilization Stages of a Sea Urchin, Hemicentrotus pulcherrimus (말똥성게 (Hemicentrotus polcherrimus)의 수정전과 초기 발생동안 RNA 및 단백질합성의 변화)

  • Jang, Jeong-Won;Lee, Yang-Rim
    • The Korean Journal of Zoology
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    • v.28 no.2
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    • pp.71-84
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    • 1985
  • Syntheses of RNA and protein were studied to examine changes in activating stored mRNAs during the early development of a sea urchin, Hemicentrotus pulcherimus. The rates of RNA and protein syntheses are very low in the unferilized eggs but the protein synthesis is activated upon the fertilization, while RNA synthesis remains still inactive at the same stage. These rates increase drastically at the blastula and gastrula stages, although the increases are not exactly in parallel. The protein synthesis was found to be also changing in quality during the early development from the studies by the two-dimensional gel electrophoresis.

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Race-Free Programmable Synthesis of A Sequential System Decribed by a GRAFCET (GRAFCET로 기술된 순서이론 시스템의 Race 없는 프로프램으로써의 합성)

  • 광준우
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.21 no.6
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    • pp.56-63
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    • 1984
  • This paper proposes a programmed logic realization of sequential logic system with parallel sequences which is described by a GRAFCET. For this purpose, an algorithm is proposed, which decomposes the GRAFCET with parallel sequence into a set of state graph without changing the physical meaning, which is applied to all kinds of GRAFCET, and which divides the system into sub-systems and vice versa. A systematic implementation by microprogrammed logic using ROM is proposed, which expands the number of selection sequence.

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A Study on the IC, Implementation of High Speed Multiplier for Real Time Digital Signal Processing (실시간 디지털 신호 처리용 고속 MULTIPLIER 단일칩화에 관한 연구)

  • 문대철;차균현
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.15 no.7
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    • pp.628-637
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    • 1990
  • In this paper we present on architecture for a high sppeed CMOS multiplier which can be used for real-time digital signal processing. And a synthesis method for designing highly parallel algorithms in VLSI is presented. A parallel multiplier design based on the modified Booth's algorithms and Ling's algorthm. This paper addresses the design of multiplier capable of accpting data in 2's complement notation and coefficients in 2's complement notation. Multiplier consists of an interative array of sequential cells, and are well suited to VLSI implementation as a results of their modularity and regularity. Booth's decoders can be fully tested using a relatively small number af test vector.

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HDL Codes Generator for Cyclic Redundancy Check Codes (순환중복검사 부호용 하드웨어 HDL 코드 생성기)

  • Kim, Hyeon-kyu;Yoo, Ho-young
    • Journal of IKEEE
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    • v.22 no.4
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    • pp.896-900
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    • 2018
  • Traditionally, Linear Shift Feedback Register (LFSR) has been widely employed to implement Cyclic Redundant Check (CRC) codes for a serial input. Since many applications including network and storage systems demand as high throughput as ever, various efforts have been made to implement CRC hardware to support parallel inputs. Among various parallel schemes, the look-ahead scheme is one of the most widely used schemes due to its short critical path. However, it is very cumbersome to design HDL codes for parallel CRC codes since the look-ahead scheme is inevitable to consider how register and input values move in the next cycles. Thus, this paper proposes a novel CRC hardware generator, which automatically produces HDL codes given a CRC polynomial and parallel factor. The experimental results verify the applicability to use the proposed generator by analyzing the synthesis results from the generated HDL code.

Regulation of Lipoprotein Lipase by Fasting in Epididymal and Mesenteric Adipocytes of Rats

  • Lee, Jae Joon;Chung, Chung Soo;Lee, Myung Yul
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.5
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    • pp.715-722
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    • 2008
  • There are marked variations in the activity of lipoprotein lipase (LPL) among adipose depots. The aim of this study was to compare the mechanisms of 24 h of fasting on LPL regulation between epididymal (EPI) adipocytes and mesenteric (MES) adipocytes in rats. 1-Day fasting consistently decreased activities of heparin-releasable LPL, total extractable LPL and cellular LPL markedly in both EPI and MES fat pads. LPL activity in MES fat pads was relatively lower than in the EPI fat pads. Consistent with data on LPL activity, the levels of expression of LPL mRNA in both nutritional states were lower in MES than EPI adipose tissue and isolated adipocytes. The decreased LPL activity after 1 day of fasting in MES adipocytes was explained mainly by a 50% decrease in the relative abundance of LPL mRNA level and a parallel 50% decrease in relative rate of LPL synthesis. In contrast, fasting of 1 day in EPI adipocytes decreased total LPL activity by 47% but did not affect LPL mRNA level or relative rate of LPL synthesis. A decrease in overall protein synthesis contributed to the decreased LPL activity after 1 day fasting both in EPI and MES adipocytes. In MES adipocytes the decrease in LPL activity, LPL mRNA and LPL synthesis were comparable, but in EPI adipocytes the changes in LPL activity were substantially larger than the changes in LPL mRNA level and LPL synthesis. Therefore, fasting decreased fat cell size, LPL activity, LPL mRNA level and relative rate of LPL synthesis in rats, and these effects were more marked in the MES adipocytes. These results clearly demonstrate the regional variations in the metabolic response of adipose tissue and LPL functions to fasting.