• KSBB Journal
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• 제9권2호
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• pp.211-223
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• 1994

4l 교반식 생물반응기에서, celite담체에 고정화된 Tolypocladium inflatum 균주 배양시의 산소전달 계수($k_La$)가 같은 세포농도 하에서 액상배양시의 값과 비교할 때, 고정상균주의 높은 비산소흡수율에도 불구하고, 2배 이상 증가되었다. 그 결과 고정상배 양의 경우, 용존산소량이 포화상태의 75%를 초과하는 충분한 산소량이 배양기간 내내 유지될 수 있었으나, 액상배양의 경우에는 용존산소량이 포화상태의 50% 이하까지 감소되었다. 임펠러의 교반속도에 따른 $k_La$의 단순 선형 의존 현상이, 250rpm에서 550rpm 범위에서 고정상배양 및 액상배양 모두에서 관찰되었으며, 그 의존정도는 액상배양의 경우 세포 농도와 함수관계인 반면, 고정상배양의 경우에는 세포농도와 무관하였다. 반면에 두 배양시스템 모두에서, 통기율 변화에 따른 산소전달율은 2.5vvm까지는 함수관계를 보였으나 그 의존도는 임펠러 교반속도의 변화에 따른 영향과 비교할 때 훨씬 미미하였으며, 2.5vvm 이상의 통기율에서는 산소전달현상에 별로 영향을 주지 못했다. CyA 생산 면에서 볼 때, 고정상세포는 형태학 또는 생리학적으로 훌륭한 배양상태를 유지할 수 있어서, 동일조건의 액상배양과 비교해서 약 2배 이상 생산성이 증가되였다. 그러므로 교반식 생물반응기를 이용한 celite-고정상배양법 은 고농도배양이 가능하다는 측면에서 볼 때, CyA 대량생산 산업화를 위한 대체 공정으로서 훌륭한 전망을 제시해 준다.

• 대한의생명과학회지
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• 제10권3호
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• pp.179-186
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• 2004

We examined a role of proteasome, the non-lysosomal multicatalytic protease complex,on the differentiation of chick embryonic myoblasts in culture. The peptide hydrolyzing activities of proteasome were found to change; the hydrolyzing activity against N-succinyl-Leu-Leu- Val- Tyr-7 -amido-4-methy1coumarin (SLLVY-AMC) was prominent and increased with myogenic differentiation. Proteasome inhibitors, N-carbobenzoxy-Leu-Leu-norvalinal (MG115) and N-carbobenzoxy-Ile-Glu (O-t-butyl)-Ala-Leucinal (PSI), blocked membrane fusion of myoblasts as well as the SLLVY-AMC hydrolyzing activity. Those inhibitory activities of the agents occurred in parallel, but were reversible and both cell fusion and the peptidase activity were restored when the agents were withdrawn from the culture medium. On the other hand, the agents caused accumulation of the ubiquitinylated proteins in the cytoskeletal proteins. These results suggest that each of the peptide hydrolyzing activities of proteasome is independently regulated during the myogenic differentiation and the chymotrypsin-like activity may play an important role in that process.

• 대한의생명과학회지
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• 제22권4호
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• pp.215-219
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• 2016

The problems of tuberculosis and its drug resistance are very severe. Therefore, rapid and accurate drug susceptibility assay is required. Recently, there has been an increased understanding of the genetic mechanism of Mycobacterium tuberculosis (MTB) drug resistance as well as advancement of molecular technologies. While many gene mutations correlate well with drug resistance, many genes do not show a strong correlation with drug resistance. For this reason, the current study assessed the utility of rpoB mRNA as a target to detect live mycobacteria. In this study, RT-PCR targeting of rpoB mRNA in BCG treated with rifampin was performed. Conventional RT-PCR and real-time PCR targeting rpoB mRNA as well as 85B mRNA was performed to determine whether these two methods could distinguish between viable and non-viable MTB. The levels of rpoB and 85B mRNA detected by RT- PCR were compared in parallel with colony forming unit counts of BCG that were treated with rifampin for different periods of time. The data suggests that that even though both mRNA levels of rpoB and 85B decreased gradually when rifampin-treatment increased, the rpoB mRNA seemed to represent live bacteria better than 85B mRNA. This study clearly indicates that RT-PCR is a good method to monitor viable cell counts in the liquid culture treated with the anti-tuberculosis drug.

• 복식문화연구
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• 제16권1호
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• pp.181-203
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• 2008

This study suggests a model to identify relationships between Supply Chain Partnership(SCP) and the performance of Supply Chain Management(SCM) based on apparel companies and outsourcing suppliers of finished products that are in a position of getting into Supply Chain Level on apparel industry. This research model is based on an integrated model including a relationship between relationship formation factors and partnership strengthening factors in SCP; and supply chain performance a result of that relationship. The formation factors of SCP affect emotional elements(trust, commitment) of strengthening factors, and they, in turn, impact the performance of a supply chain through behavioral elements(collaboration, information sharing)16 hypotheses were formulated to research the degree of impact of SCP on supply chain performance. Theoretical and empirical research was executed in parallel to achieve the objectives of this study. Empirical research involved a research methodology using surveys. Survey target audiences were limited to designers and merchandisers over five years of experience with apparel companies and outsourcing suppliers for finished products operating mainly in Korea. SPSS 12.0 for Windows and AMOS 5.0 were used for data and statistical analysis. Reviewing the result of research model and identification of each hypothesis, total 11 from 16 hypotheses set by this research were selected, 5 hypotheses were dropped, and 4 meaningful paths were added.

• International Journal of Advanced Culture Technology
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• 제8권3호
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• pp.192-197
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• 2020

Foreign students in South Korea face important challenges when they try to maintain their health. As a measure of their motivation to actively build skills for overcoming those challenges, we evaluated the 10-item Consumer Health Activation Index (CHAI), testing its feasibility, dimensionality, and reliability. There were no missing data, there was no floor effect, and for the total scores the ceiling effect was trivial (< 2%). Results of the Kaiser-Meyer-Olkin test and Bartlett's test of sphericity indicated that the data were suitable for the detection of structure by factor analysis. The results of parallel analysis and the shape of the scree plot supported a two-factor solution. One factor had 3 items concerning "my doctor" and the other factor had the 7 remaining items. Reliability was high for the 10-item CHAI (alpha = 0.856), for the 3-item subscale (alpha = 0.838), and for the 7-item subscale (alpha = 0.857). Reliability could not be improved by deletion of any items. Use of the CHAI to gather data from these foreign students is feasible, and reliable results can be obtained whether one uses the total score from all 10 items or scores from the proposed 7-item and 3-item subscales.

• 한국의사학회지
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• 제16권1호
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• pp.137-160
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• 2003

The GyoJungEuiSeoGook(校定醫書局, the bureau for revising of medical books) which was established in the 2nd year of InJong GaWoou of Song dynasty, made comparative analyzation about various kinds of publication and reference materials of all classical medical books that was published until Jin Han and Su Dang dynasty, revised the medical books like as Bozushinnongboncho(補注神農本草), Zungkwangbozuhwangjenegyungsomun(重廣補注黃帝內經素問), Shanghanlon(傷寒論), Bigupchunggumyobang (備急千金要方), Magkyung(脈經), Oedaebiyo(外臺備要), Hwangjechimgugapeulgyung(黃帝鍼灸甲乙經), Cchunggumikbang(千金翼方) etc. The signification of such revision was not only to preserve the materials which may be lost before, bibliographically and also make the books of Hwangjenegyung(黃帝內經), Shanghanlon(傷寒論) etc. become more regularly. And it made the foundation of Korean Medical research depends on the documentary records so as to make it have big development by deductive method till the beginning of modern age. The success of GyoJungEuiSeoGook(校定醫書局) indicates that the stagnation of Korean Medical research due to it's behind with the development of politics-economy, social culture and scientific technology which based on western scientific culture. So we may draw the conclusion that the success of scientific research needs to parallel with the external and internal factors of the surrounding science.

• 복식문화연구
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• 제24권6호
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• pp.873-885
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• 2016

It is common knowledge that a conventionally woven textile consists of two assemblies of parallel threads (warp and weft), one interlaced with the other at ninety degrees. Where each of the two assemblies is arranged in a particular colour sequence, a check design, known as a 'tartan', may be created. Although similar check-type cloths have been produced worldwide, it is the tartans of Scotland which have received most attention and it is here that a complex set of rules evolved and tartans of different types became associated traditionally with different regions, family groups or 'clans'. There is an impressive array of publications focused on the identification of tartans and their clan associations. This paper explains the nature of tartans, analyses typical surface structures, ratios and proportions, and suggests possible avenues of use for modern designers. The principal sources of data were a collection of tartans held at ULITA - An Archive of International Textiles (University of Leeds, UK) and Stewart's 1974 publication The Setts of Scottish Tartans. Based on the observation that divisions into halfs and thirds were dominant, a series of templates is presented with the intention of developing an awareness among designers that ratios and proportions used in familiar or traditional frameworks can be employed in a modern context.

• 복식
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• 제59권4호
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• pp.111-125
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• 2009

The period from the early years of the 21st Century, when the birth of Digital Clothing received as a kind of digital cultures in the modern information society, to the present time, the period is studied on as a social transition in the revolutionary digital technology in parallel with the fashion changes which have an effect on our thoughts and our life style. After the 2000's, when digital was perceived as a culture, information technology came into being owing to the technological development in the network and informative and communicative technology. This study tried to grasp the tendency of the times to Digital Clothing, which occurred in the new situation of Digital Technology, and then on the base of it, tried to classify the expressive characteristics in the Digital Clothing as the Cyberspace, Global Network, high functionality Smart Textiles and digital technology. The social reformation by the revolutionary digital technology is coming forth in the New Fashion of the digital Clothing, with the development of technology and network in the Cyberspace and real space. the Digital Clothing which led to the revolutionary change in New Fashion occurred, and by the same time, gradually the phenomena of Digital Consuming Culture is expansive.

• 대한한의학회지
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• 제25권1호
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• pp.96-110
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• 2004

The GyoJungEuiSeoGuk(교정의서국, the bureau for revising of medical books) which was established in the 2nd year of InJong GaWoou of Song dynasty, made comparative analyzation about various kinds of publication and reference materials of all classical medical books that was published until Jin Han and Su Dang dynasty, revised the medical books like as Bozushinnongboncho(보주신농본초), Zungkwangbojuhwangjenegyungsomun(중황보주황제내경소문), Shanghanlon(상한론), Bigupchunggumyobang (비급천금요방), Magkyung (맥경), Hwangjechimgugapeulgyung(황제침구갑을경), Oedaebiyo (외대비요), Chunggumikbang(천금익방) etc. The signification of such revision was not only to preserve the materials which may be lost before, bibliographically and also make the books of Hwangjenegyung(황제내경), Shanghanlon(상한론) etc. become more regularly. And it made the foundation of Korean Medical research depends on the documentary records so as to make it have big development by deductive method till the beginning of modem age. The success of GyoJungEuiSeoGuk indicates that the stagnation of Korean Medical research due to $it^{circ}{\Phi}s$ behind with the development of politics-economy, social culture and scientific technology which based on western scientific culture. So we may draw the conclusion that the success of scientific research needs to parallel with the external and internal factors of the surrounding science.

• 복식문화연구
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• 제25권5호
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• pp.708-717
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• 2017

Industrial innovation in Britain, during the eighteenth and nineteenth centuries, stimulated the introduction of the factory system and the migration of people from rural agricultural communities to urban industrial societies. The factory system brought elevated levels of economic growth to the purveyors of capitalism, but forced people to migrate into cities where working conditions in factories were, in general, harsh and brutal, and living conditions were cramped, overcrowded and unsanitary. Industrial developments, known collectively as the 'Industrial Revolution', were driven initially by the harnessing of water and steam power, and the widespread construction of rail, shipping and road networks. Parallel with these changes, came the development of purchasing 'middle class', consumers. Various technological ripples (or waves of innovative activity) continued (worldwide) up to the early-twenty-first century. Of recent note are innovations in digital technology, with associated developments, for example, in artificial intelligence, robotics, 3-D printing, materials technology, computing, energy storage, nano-technology, data storage, biotechnology, 'smart textiles' and the introduction of what has become known as 'e-commerce'. This paper identifies the more important early technological innovations, their influence on textile manufacture, distribution and consumption, and the changed role of the designer and craftsperson over the course of these technological ripples. The implications of non-ethical production, globalisation and so-called 'fast fashion' and non-sustainability of manufacture are examined, and the potential benefits and opportunities offered by new and developing forms of social media are considered. The message is that hand-crafted products are ethical, sustainable and durable.