• 제목/요약/키워드: Pandemic

검색결과 2,272건 처리시간 0.027초

A protein interactions map of multiple organ systems associated with COVID-19 disease

  • Bharne, Dhammapal
    • Genomics & Informatics
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    • 제19권2호
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    • pp.14.1-14.6
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    • 2021
  • Coronavirus disease 2019 (COVID-19) is an on-going pandemic disease infecting millions of people across the globe. Recent reports of reduction in antibody levels and the re-emergence of the disease in recovered patients necessitated the understanding of the pandemic at the core level. The cases of multiple organ failures emphasized the consideration of different organ systems while managing the disease. The present study employed RNA sequencing data to determine the disease associated differentially regulated genes and their related protein interactions in several organ systems. It signified the importance of early diagnosis and treatment of the disease. A map of protein interactions of multiple organ systems was built and uncovered CAV1 and CTNNB1 as the top degree nodes. A core interactions sub-network was analyzed to identify different modules of functional significance. AR, CTNNB1, CAV1, and PIK3R1 proteins were unfolded as bridging nodes interconnecting different modules for the information flow across several pathways. The present study also highlighted some of the druggable targets to analyze in drug re-purposing strategies against the COVID-19 pandemic. Therefore, the protein interactions map and the modular interactions of the differentially regulated genes in the multiple organ systems would incline the scientists and researchers to investigate in novel therapeutics for the COVID-19 pandemic expeditiously.

Critical Factors Affecting Masks Purchasing Intention of Consumers During COVID-19 Pandemic: An Empirical Study in Vietnam

  • TRAN, Toan Khanh Pham
    • The Journal of Asian Finance, Economics and Business
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    • 제8권5호
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    • pp.1011-1017
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    • 2021
  • An effective measure to prevent the spread of COVID-19 is wearing masks in public places. This solution is highly recommended in many countries all over the world. The objective of this study is to identify the antecedents of citizens' intention to purchase masks during the COVID-19 pandemic. Based on the theory of planned behavior (TPB), the current study analyzes attitudes toward mask-purchasing, subjective norms, and perceived behavioral control, to assess their impact on intention to purchase masks. In total, six variables are examined: attitude toward mask-wearing, subjective norms, perceived behavioral control, perceived severity, perceived susceptibility, and the intention to wear masks. Data are collected from 243 respondents in Ho Chi Minh City, Vietnam. They were processed through by factor analysis and multiple regressions. The results report that all three factors positively affect citizens' intention to buy masks in the following ascending order: Attitude toward mask-purchasing, subjective norms, and perceived behavioral control. Our study is the first research that applies TPB to investigate citizens' intention to purchase masks to during the COVID-19 pandemic. Moreover, this study provides guidelines to the Vietnamese public managers to combat COVID-19 through the purchase of masks. Shopkeepers would be well advised to observe the intentions of consumers toward masks.

COVID-19에 의한 EMS 동반손상 (Collateral damage of emergency medical services due to COVID-19)

  • 이남진;양진철;문준동
    • 한국응급구조학회지
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    • 제25권3호
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    • pp.189-200
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    • 2021
  • Purpose: We aimed to provide effective emergency medical services (EMS) response strategies for coping with high acuity patients during the pandemic by analyzing the influence of the COVID-19 and social distancing on EMS. Methods: In this retrospective observational study, we analyzed the distribution of high acuity patients transported by Daejeon 1-1-9 EMS during the COVID-19 pandemic period, between February 1, 2020 and October 31, 2020 and the same period in 2019, as well as the level 3 social distancing enforced period, between July 27, 2020 and October 31, 2020. Results: The EMS dispatches decreased by 17% during the observed COVID-19 pandemic period compared to the same period in 2019. The number of cases with cardiac arrest and positive prehospital stroke scale rose by (p<.001). Patients with cardiac arrest, trauma, and positive prehospital stroke scale increased by during the level 3 social distancing period. Conclusion: Unlike the decreased EMS call volume and patient transports during the COVID-19 pandemic, cardiac arrest cases and the severity of high acuity patients tended to increase. We suggest that EMS systems should contrive a response strategy considering the collateral effect of major epidemics on the incidence rate of high acuity patients.

Exploring the Factors That Influence Unexpected Change of E-Customer Behaviour and Perceived Cybercrime Risk during COVID-19 in Saudi Arabia

  • Ibrahim, Rehab;Li, Alice;Soh, Ben
    • International Journal of Computer Science & Network Security
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    • 제21권12호
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    • pp.101-109
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    • 2021
  • Cybercrimes are the biggest threat that can influence the future of e-commerce, particularly in difficult times such as the COVID-19 pandemic. This pandemic has resulted in noticeable changes in e-customer behaviour represented in three types: spending rates, types of goods bought, and the number of purchasing times. Moreover, the percentage of cybercrime in many countries, including Saudi Arabia, has increased during the pandemic. The increase in the number of cybercrimes during the COVID-19 crisis and the changes in consumer behaviour shows that there is an urgent need to conduct research on the factors that have led to this. This study will explore the most significant factors that have an effect on the unexpected change of customer behaviour and cybercrime perceived risk during the COVID-19 pandemic in Saudi Arabia. The finding of the study will hopefully contribute to attempts in finding safer methods for shopping online during COVID-19 and similar crisis.

Global Changing of Consumer Behavior to Retail Distribution due to Pandemic of COVID-19: A Systematic Review

  • TIMOTIUS, Elkana;OCTAVIUS, Gilbert Sterling
    • 유통과학연구
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    • 제19권11호
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    • pp.69-80
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    • 2021
  • Purpose: Consumers have unique behaviors that are classified based on their interests and considerations before buying. They are predicted will change due to the pandemic of COVID-19. This study provides insights for retailers about the dynamic of consumer behavior before and during the pandemic, including future predictions. Research design, data and methodology: The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement was applied in this study. Seven studies that were selected from five databases meet the criteria for cohort and cross-sectional analyses of gender, age, store types, and environmental concerns. Results: Consumer's gender and age contribute to consumer behavior change. Both offline and online stores can be integrated as omnichannel rather than substitute each other. Product distribution and consumer budget need to be reevaluated by retailers, while internet security is the most essential factor when developing their online transactions. Conclusions: COVID-19 pandemic has a significant impact on changing consumer behavior in most countries. Retailers are encouraged to adapt to the changes by modifying their business model with technology. However, it is still speculated and cannot be generalized due to different cultural and contextual factors. Future studies are always needed to synchronize along with the transition of consumers' behavior.

The Role of Business Capabilities in Supporting Organization Agility and Performance During the COVID-19 Pandemic: An Empirical Study in Indonesia

  • WANASIDA, Albert Surya;BERNARTO, Innocentius;SUDIBJO, Niko;PURWANTO, Agus
    • The Journal of Asian Finance, Economics and Business
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    • 제8권5호
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    • pp.897-911
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    • 2021
  • This study aims to analyze the important role of business analytics capability, information quality, and innovation capability in influencing organization agility and organization performance during the Covid-19 pandemic. Data was collected from 76 companies from various sectors in Indonesia. Structural Equation Model-Partial Least Square (SEM-PLS) analysis was conducted to analyze the relationship between variables and test a series of hypotheses. Importance-Performance Matrix Analysis (IPMA), a useful analysis approach in PLS-SEM, is used, which extends the results of the estimated path coefficient (importance) by adding a dimension that considers the average values of the latent variable scores (performance). The IPMA approach examines not only the performance of an item but also the importance of that item. The results show that business analytics capability has a significant effect on information quality and innovation capability which then affects organization agility. Organizational performance is influenced by organizational agility. IPMA results show that organizational agility has the highest level of impact on organizational performance. This study will assist companies in planning business analytics, improving information quality, increasing innovation capability, and ultimately increasing agility and performance during the Covid-19 pandemic. This study will add to existing knowledge about previous literature, especially in the Covid-19 pandemic situation.

Mainstreaming of Health Equity in Infectious Disease Control Policy During the COVID-19 Pandemic Era

  • Choi, Hongjo;Kim, Seong-Yi;Kim, Jung-Woo;Park, Yukyung;Kim, Myoung-Hee
    • Journal of Preventive Medicine and Public Health
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    • 제54권1호
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    • pp.1-7
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    • 2021
  • The Korean government's strategy to combat coronavirus disease 2019 (COVID-19) has focused on non-pharmaceutical interventions, such as social distancing and wearing masks, along with testing, tracing, and treatment; overall, its performance has been relatively good compared to that of many other countries heavily affected by COVID-19. However, little attention has been paid to health equity in measures to control the COVID-19 pandemic. The study aimed to examine the unequal impacts of COVID-19 across socioeconomic groups and to suggest potential solutions to tackle these inequalities. The pathways linking social determinants and health could be entry points to tackle the unequal consequences of this public health emergency. It is crucial for infectious disease policy to consider social determinants of health including poor housing, precarious working conditions, disrupted healthcare services, and suspension of social services. Moreover, the high levels of uncertainty and complexity inherent in this public health emergency, as well as the health and socioeconomic inequalities caused by the pandemic, underscore the need for good governance other than top-down measures by the government. We emphasize that a people-centered perspective is a key approach during the pandemic era. Mutual trust between the state and civil society, strong accountability of the government, and civic participation are essential components of cooperative disaster governance.

Digital Technology Practices and Vaccine Campaign in Korea: International Perceptions on Health Diplomacy amid COVID-19 Crisis

  • Tahira, Iffat
    • Journal of Contemporary Eastern Asia
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    • 제21권2호
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    • pp.27-46
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    • 2022
  • The purpose of this study is two-fold: first, to discuss the concept of health diplomacy and the Korean government's response to contain the COVID-19 pandemic; second, to assess and compare assumptions of variances about foreigners' perceptions of how Korea is leveraging digital technology in battling the coronavirus spread, and its vaccine campaign; through the lenses of Chinese, Filipino, and Pakistani foreign nationals who are currently living in Korea. A total of 219 foreigners responded to the survey. The collected data were analyzed as percentages, mean averages, t-test, and ANOVA for statistical analysis. Results show that Korea is utilizing its digital technology practices and vaccine campaign in battling the pandemic through efforts of health diplomacy. ANOVA indicated significant results and assumptions of variance across three ethnic groups showing the Pakistani population had higher mean scores than the Chinese and Filipino about Korea's health diplomacy during the pandemic. This study contributes to the literature on Korea's digital technology practices and vaccine campaigns amidst the COVID-19 pandemic by promoting its image through health diplomacy efforts. It projects the country's soft image on a global scale, to save the lives of locals and foreign nationals, by providing insights into health diplomacy in Korea.

The Influence of the COVID-19 Pandemic on Stock Market Returns in Indonesia Stock Exchange

  • HERWANY, Aldrin;FEBRIAN, Erie;ANWAR, Mokhamad;GUNARDI, Ardi
    • The Journal of Asian Finance, Economics and Business
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    • 제8권3호
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    • pp.39-47
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    • 2021
  • This research aims to confirm if the COVID-19 pandemic has had an impact on existing sectors, and how that affects the Indonesian Stock Exchange (IDX) market returns. The research method used is an event study employing market models in nine sectors of the Exchange with purposive sampling technique, and supported by Ordinary Least Square (OLS) regression. Based on the calculation of abnormal returns in the period of 30 days before up to 30 days after, the financial property, real estate, and construction sector results show a decreased abnormal return value. The infrastructure, utilities, and transportation sectors also show an abnormal return value that tends to be constant, while the abnormal return value increases in other sectors. Judging from the cumulative value of abnormal returns, the most affected sector is financials, followed by the trade, service, and investment sectors. The consumer goods and mining industry sectors are still optimistic, while other sectors show temporary negative sentiment. Overall, the stocks on the Indonesia Stock Exchange (IDX) were affected by the COVID-19 pandemic with a cumulative negative value of the average abnormal return sample. The results using OLS regression also strengthen the relationships between the COVID-19 pandemic, and negative and significant market returns.

E-Commerce Readiness of Creative Industry During the COVID-19 Pandemic in Indonesia

  • PRIAMBODO, Ivan Triyogo;SASMOKO, Sasmoko;ABDINAGORO, Sri Bramantoro;BANDUR, Agustinus
    • The Journal of Asian Finance, Economics and Business
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    • 제8권3호
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    • pp.865-873
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    • 2021
  • COVID-19 pandemic has brought the world into economic recession. This study aims to present an analysis of the readiness of creative e-commerce in Indonesia. Data was collected from various locations that may represent the Creative Industry in Indonesia. The quantitative method has been applied as a research approach by gathering questionnaires from 383 business owners selected using the cluster random sampling method. Based on the results of the analysis and discussion, it is concluded that E-Commerce Readiness is very important in times of uncertainty such as the COVID-19 pandemic. The level of readiness will determine the continuity and sustainability of a company or business in a volatile business environment. E-Commerce Readiness can be evaluated based on Technology Readiness, Organizational Readiness, and Environmental Readiness. Not all perspectives are taken into consideration in making decisions about the implementation or improvement of E-Commerce in the pandemic period. Technology Readiness is seen as the most significant impact on a company's ability to cope with volatility, while Environmental Constraints encourage businesses to adopt E-Commerce and take it to the next level. On the other hand, Organizational Readiness has no effect on the E-Commerce readiness of the company because the company or organization does not consider this aspect.