• Title/Summary/Keyword: Palladium

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Synthesis of N-Substituted Isoindolin-1-ones via Palladium-Catalyzed Carbonylative Heterocyclization of o-Bromobenzylbromide with Carbon Monoxide and Primary Amines

  • 심상철;Li Hong Jiang;이동엽;조찬식
    • Bulletin of the Korean Chemical Society
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    • v.16 no.11
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    • pp.1064-1067
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    • 1995
  • A convenient method for the synthesis of N-substituted isoindolin-1-ones is disclosed in palladium(0)-catalyzed heterocyclization of o-bromobenzylbromide with carbon monoxide (CO) and primary amines in DMF at 100 ℃.