• Journal of Korean Medicine Rehabilitation
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• v.24 no.3
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• pp.111-119
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• 2014

Objectives This study aims to analyze a thermal distribution in biological living tissue during warm needling therapy by using a finite element method. The analysis provides an understanding of warm needling's efficacy and safety. Methods A model which consisted of four-layered tissue and stainless steel needle was adopted to analyze the thermal distribution in living tissue with a bioheat transfer analysis. The governing equation for the analysis was a Pennes' bioheat equation. A heat source characteristic of warm needling therapy was obtained by previous experimental measurements. The first analysis of the time-dependent temperature distribution was conducted through points on a boundary between the needle and the tissue. The second analysis was conducted to visualize the horizontal temperature distribution. Results When heat source's peak temperatures was above $500^{\circ}C$ and temperature rising rates were relatively slow, the peak temperature at skin surface exceeded a threshold of pain and tissue damage ($45^{\circ}C$), whereas when the peak temperature was around $400^{\circ}C$, the peak temperature at the skin surface was within a safe limit. In addition, the conduction of combustion energy from the moxa was limited to the skin layer around the needle. Conclusions The results suggest that the skin layer around the needle can be heated effectively by warm needling therapy, but it appears to have little effect at the deeper tissue. These findings enhance our understanding of the efficacy and the safety of the warm needling therapy.

• The Journal of Korean Physical Therapy
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• v.13 no.2
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• pp.293-303
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• 2001

The purpose of this study was to determine if there were any beneficial effects of massage or microwave diathermy regarding delayed onset muscle soreness (DOMS) and indices of muscle damage. Twenty-one adult women, randomly divided in two treatment groups and a control group, performed eccentric stepping exercise with the quadriceps until exhaustion. The treatment groups additionally performed massage or microwave diathermy after the stepping exercise. Pressure pain threshold measure for DOMS and muscle enzymes in the blood were obtained before, and 0, 24, 48 and 72 hours after exercise. The results were as follows; 1. Eccentric exercise caused DOMS and elevations of muscle enzymes in the blood, with peak values exercise levels by 24 hours after exercise and GOT and CRP by 72 hours after exercise. DOMS and CK activity remained elevated 72 hours after exercise. 2. DOMS and blood muscle enzymes response to eccentric exercise were reduces by massage or micro diathermy therapy. DOMS was significantly decreased at 72 hours after exercise by massage and microwave diathermy. CK activity was significantly decreased at 72 hours after exercise by microwave diathermy. There was the significant reduction in LDH at 48 hours, GOT at 24, 48, 72 hours. and CRP at 24, 48 hours after exercise by massage and microwave diathermy. These results indicate that massage or microwave diathermy is had effect on recovery from exercise-induced muscle damage. In our's suggestion. microwave diathermy is particularly more appropriate therapeutic modality because it is more simple and economic than massage.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.5 no.2
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• pp.85-93
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• 2007

Summary of background data: It is researched until now and the researches against the effect of position cold treatment the effect which pain threshold, change of skin temperature, researches the effective stiffness, the coldness in the patient it applied and relax an inflammation do the researches against were insufficient. Purpose: This project was to see how much it gives effect by using the cold air therapy an inflammation relief of rheumatoid arthritis patient. Methods: The medical subjects were 10 people from standard to diagnosis category of American College of Rheumatology(ACR) who had rheumatoid arthritis and to inspect informations about inflammation relief, have inspected ESR(erythrocyte sedimentation rate) and WBC(white blood cells). The experiment method was to let the patient bend the joint and lay down flat and treat with cold air from 10 cm away from joint line repeating 5 minutes treatment 1 minute rest and 3 minutes treatment. ESR and WBC cold air therapy reported with 5 days gap and each patient has been applied for 3 times. Result: The 5th day and 10th days ESR and WBC value shows when using cold air therapy, there was a reduction on rejected group but didn't last long, but 15th day it showed only on WBC it had its attention. Conclusions: So the cold air therapy shows it has positive effects on inflammation relief of rheumatoid arthritis patient.

• Journal of Acupuncture Research
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• v.23 no.3
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• pp.155-163
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• 2006

Objectives : This study was designed to evaluated the effect of electro acupuncture on Heart Rate Variability of Patients with functional voiding disease. Methods: Subjects were voluntarily recruited by newspapers and internet. Electro acupuncture was performed three times a week for 3 weeks. Acupuncture point for EA group was B32, Electrical stimulation frequency was 2Hz, duration 20min, and intensity was up to pain threshold according to patients. The patients' Heart Rate Variability was measured before, after 3 weeks of treatment for 5 minutes. Results : In time domain analysis, There were significant increase of SDNN and RMSSD(p<0.05) after 3 weeks treatment. In frequency domain analysis, There were significant increase of LF and LF /HF ratio(p<0.05) after 3 weeks treatment. There were no significant changes in other components of heart rate variability. Conclusion : This study suggests that electroacupuncture treatments can be applicable to improve autonomic nervous system in patients with functional voiding disease.

• The Journal of Korean Medicine
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• v.26 no.2 s.62
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• pp.176-181
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• 2005

Objectives: This study was designed to evaluate the effect of moxibustion on UPDRS and heart rate variability of patients with Parkinson's disease. Methods: Subjects were voluntarily recruited through newspapers and internet. All subjects were confirmed as showing idiopathic Parkinson's disease by a neurologist. Moxibustion therapy was performed 5 times a week by the patient's family at home and once a week by an oriental medical doctor in hospital. Moxibustion points were GV20, CV12, ST36, BL18, and BL20. Intensity was up to pain threshold to prevent patients getting burned. The patient's symptoms were assessed before and after 8 weeks of treatment by unified Parkinson's disease rating scale (UPDRS). Heart rate variability was measured for 5 minutes before and after the treatments. Results: Total UPDRS scores were significantly improved after 8 weeks compared to pre-treatment (p<0.05). There were significant decrease of mean heart rates (p<0.05) and increase of SDNN and TP (p<0.05) after 8 weeks' moxibustion treatments. There were no significant changes in other components of heart rate variability. Conclusions: This study suggests that moxibustion treatments can be applicable to improve not only symptoms but also heart rate variability in the patients with idiopathic Parkinson's disease.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1998.11a
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• pp.178-178
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• 1998

We reported that the hexane fraction of Torilis Fructus have an anti-inflammatory and analgesic effect. Therefore, in order to isolate the active compound, the hexan fraction of Torilis Fructus was chromatographed on silica gel column. The subfraction of hexane fraction was crystallized as colorless stout needles. The chemical structure of this compound was verified to be torilin through m.p., UV, IR, GC-MS, and NMR spectral data. In pharmacological tests, torilin exhibited strong anticarrageenan activity at the dose of 90 and 270 mg/kg, p.o. in rats, and it had inhibitory effect on the vascular permeability at the dose of 30 and 90 mg/kg, p.o. in mice. Torilin showed potent inhibition of leucocyte emigration in CMC-pouch at the dose of 3 and 9 mg/rat, s.c. Torilin have the analgesic effect at the dose of 30, 90 and 270 mg/kg, p.o. in both of the acetic acid- and phenyl-p-benzoquinone-induced writhing syndrome. It also increased the pain threshold at the dose of 30, 90 and 270 mg/kg, p.o. in the tail pressure method and the Randall-Selitto method. Torilin did not show a hypothermic action at the dose of 30 and 90 mg/kg, p.o. in mice. The acute toxicity of torilin was very weak: the LD$\_$50/ value was more than 5000 mg/kg, p.o. and 2000 mg/kg, Lp. in mice. From the above mentioned results, it was suggested that torilin had potent anti-inflammatory and analgesic activities in animals.

• Journal of Periodontal and Implant Science
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• v.26 no.2
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• pp.522-530
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• 1996

Most dentists are very interested in laser therapy on the intraoral soft tissue lesions because they want to accomplish the analgesic and aseptic surgery with little or no bleeding. In order to determine the difference of pain threshold according to different gingival tissues with or without inflammation, 25 patients with inflammatory periodontal disease and 10 volunteers with good general and oral health were selected as the inflamed group and the normal group, respectively. Interdental papilla, marginal gingiva, attached gingiva, and alveolar mucosa were irradiated by the contact delivery($300{\mu]m$ fiber optic, for 5 seconds) of a pulsed Nd:YAG laser(EN.EL.EN06O, Italy). And the laser power was gradually increased from 0.5W by the increment of 0.1W. The highest laser power was recorded as the first painful power when the painful gesture was recognized at first. The difference of the first painful power of laser according to different gingival tissues with or without inflammation was statistically analyzed by paired t-test in MICROSTAT program. Following results were obtained: 1. In the comparison related with the inflammation, the first painful power was significantly lower in the inflamed group than in the normal group, regardless of interdental papilla and marginal gingiva(p<0.05). 2. In the comparison related with the tissue structure, the first painful. power was significantly lower in alveolar mucosa than in attached gingiva(p<0.05). The results suggest that, for the painless therapy by a pulsed-Nd:YAG laser irradiation, the laser surgery over 2.0W of power should be necessarily accomplished under the local anethesia, and the local anesthesia should be considered according to the degree of inflammation, the tissue structure, and the purpose of laser therapy.

• The Korean Journal of Physiology
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• v.24 no.2
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• pp.389-402
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• 1990

The physiological characteristics of the neurons receiving the ventral root afferent inputs were investigated in the cat. A total of 70 cells were identified in the lumbosacral spinal cord. All these cells responded only to the C-strength stimulation of the distal stump of cut ventral root and the estimated conduction velocities of the VRA fibers were not faster than 4 m/sec. The majority of them were silent in resting state. For 49 cells, their peripheral receptive fields were characterized. Among them, 25 cells were exclusively excited by VRA inputs, 8 were inhibited and the remaining cells recevied both excitatory and inhibitory VRA inputs. According to the response pattern to the mechanical stimuli applied to their receptive fields, only a fourth of them were typical high threshold cell, a sixth, wide dynamic range cells, while remainings were a rather complex cells. Most of the cells receiving VRA inputs, received only the A ${\delta}-peripheral$ nerve inputs. Intravenous injection of morphine decreased the response of spinal cells to the VRA activation. The responses were abolished completely by counter irritation to the common peroneal nerve with C-strength-low frequency stimuli. These physiological properties of the spinal neurons receiving the VRA inputs are differ in some aspect from the spinal neurons receiving nociceptive inputs from the periphery, but still were consistent with the contention that VRA system might carry nociceptive informations arising from the spinal cord and/or neraby surrounding tissues.

• English & American cultural studies
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• v.10 no.2
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• pp.149-207
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• 2010

Written simultaneously with Prometheus Unbound, Shelley's "Julian & Maddalo" is a masterwork of dramatic poiesis, of doubling embedded in its couplets, dialogic debate on human nature and contrasted symbolic emblems. The emblems mirror each other and are themselves sites of generative paradox: the "heaven illumined" but "dreary tower" of the Maniac and the glorious sunsets on the "ever-shifting sand" of the Lido, a wasteland that is a place of self discovery but also of "abandonment" and barren mingling figured, inter alia, in its "amphibious weeds," a trope of the poem's personae. This essay also explores the poem's dramatic structure and various rhetorical devices, beginning with the Preface, a threshold of complex identity disguise that Shelley uses for veiled self-presentation, as in "Alastor," mirroring and literary references replete with nuanced ironies. I focus mainly on the complex figures of liminality Shelley uses to develop his own thoughts (as well as his ongoing debates with Byron) about man's potential for growth in thought, insight and empathy, in political reform and interpersonal and individual healing. Advancing Shelley's most optimistic ideas, Julian, escorted by Maddalo observes the Maniac, -- a living ruin whose pained eloquence reveals the link of eros to poiesis and the limits of the latter's ability to 'transform a world.' The Maniac is the core of muse-work (remembering, thinking and song) and Shelley presents him as its emblem. He also is prefigured in and reflects the quintessentially liminal Lido with its "barren embrace" of sea and land. Yet it is less the Maniac's feeling that his grief is "charactered in vain…on this unfeeling leaf" than Julian's rationales for leaving the site of pain that point to Shelley's final comment on poetry's transformative limits. As the primary haploids of the drama's meiosis re-combine and two of them, Maddalo and the maniac fall away, an analogy I briefly develop and embedded in the erotic dynamics of poiesis, Shelley suggests, as he did at the beginning of his poetic lyricism in "Alastor" and at its end in "the Triumph of Life"that images mislead and delude; that "the deep truth is imageless" and redemption is not in but beyond figuration.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.3
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• pp.100-104
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• 2022

The purpose of this study is to observe the effectiveness of the Korean medical complex treatments for functional dyspepsia (FD). And we observed NDI-K (Nepean dyspepsia index-Korean version) and algometer on acupoints to confirm the treatment effectiveness. In this retrospective study, we investigated 77 patients with FD symptoms who admitted to 00 Korean Hospital for 2 weeks from April 14, 2020 to March 31, 2021. All patietns were treated with herbal medicines, acupuncture, pharmacopuncture, moxa treatment, aroma therapy, So-jeok and So-jeok II therapy. On the day of admission and discharge, NDI-K, algometer on acupoints (CV12, CV10, ST25, ST27, SP14) were examined twice. Among the NDI-K values, all 14 items except for poor breathing were decreased statistically significantly. The algometer values were increased statistically significantly in all acupoints (CV12, CV10, ST25, ST27, SP14). These results suggest that Korean medical treatment can be useful in the treatment of FD.