• Title/Summary/Keyword: Pain: mechanism

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The Study on Somatic Referred Pain (체성 연관통(Somatic Referred Pain)에 대한 고찰)

  • Yun, Jong-Tae;Song, Yun-Kyung;Lim, Hyung-Ho
    • The Journal of Korea CHUNA Manual Medicine
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    • v.5 no.1
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    • pp.195-204
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    • 2004
  • This paper describes possible mechanism of the somatic referred pain. The study of somatic referred pain mechanism is necessary because many patients suffer from several types of muscle pain. This review compares the somatic referred pain with MPS(myofacial pain syndrome). There are similarities between these two pain mechanisms. But the therapeutics of somatic referred pain is yet remain fully unknown. Therefore this review consider origin of variable referred pain. Also it is recommendable to study referred pain mechanism in terms with oriental medical pain concept.

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The mechanism of action of pulsed radiofrequency in reducing pain: a narrative review

  • Park, Donghwi;Chang, Min Cheol
    • Journal of Yeungnam Medical Science
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    • v.39 no.3
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    • pp.200-205
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    • 2022
  • Pain from nervous or musculoskeletal disorders is one of the most common complaints in clinical practice. Corticosteroids have a high pain-reducing effect, and their injection is generally used to control various types of pain. However, they have various adverse effects including flushing, hyperglycemia, allergic reactions, menstrual changes, immunosuppression, and adrenal suppression. Pulsed radiofrequency (PRF) is known to have a pain-reducing effect similar to that of corticosteroid injection, with nearly no major side effects. Therefore, it has been widely used to treat various types of pain, such as neuropathic, joint, discogenic, and muscle pain. In the current review, we outlined the pain-reducing mechanisms of PRF by reviewing previous studies. When PRF was first introduced, it was supposed to reduce pain by long-term depression of pain signaling from the peripheral nerve to the central nervous system. In addition, deactivation of microglia at the level of the spinal dorsal horn, reduction of proinflammatory cytokines, increased endogenous opioid precursor messenger ribonucleic acid, enhancement of noradrenergic and serotonergic descending pain inhibitory pathways, suppression of excitation of C-afferent fibers, and microscopic damage of nociceptive C- and A-delta fibers have been found to contribute to pain reduction after PRF application. However, the pain-reducing mechanism of PRF has not been clearly and definitely elucidated. Further studies are warranted to clarify the pain-reducing mechanism of PRF.

A Neuroanatomical and Neurophsiolgical basic Study on the Mechanism of Acupuncture in central nervous system (침자기전(鍼刺機轉)의 중추신경계(中樞神經系)에서의 신경해부(神經解剖).생리학적(生理學的) 기초연구(基礎硏究))

  • Kim, Jeong-Heon
    • Korean Journal of Oriental Medicine
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    • v.2 no.1
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    • pp.514-550
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    • 1996
  • There are many theory in acupuncture mechanism, so we must know the detail contents. and then we can use the acupuncture as we know. the follow article will be helpful in this part. 1. Spinal cord are role in intermediate part in somatosensorypathway also in acupuncture stumulating tract 2. Acute pain pathway started in laminae I, V of gray colmn, next are the spinothalamic tract(trigeminal spinothalamic tract in above neck part) and then go to the specific thalamic nucleus. but chronic pain in laminae II, III, VI, VII, next are spinoreticular tract(trigeminal spinoreticular tract in the neck part) and finally to the nonspecific thalamic nucleus. 3. Thalamus is very important area in somatosensory stimuation including acupuncture stumulating sensory also as a pain control center. but except this, there are Hypothalamus, Limbic system Cerebral cortex and Cerebellum as intermediator. as we Know hypothalamus is related to the emotional analgesic system with a limbic system. 4. A ${\delta$ fiber has relationship in Acute, sharp and initial pain, contrary this C fiber is related with Chronic, dull and last pain. 5. In Acupuncture mechanism of pain analgesia, there are two theory, one is gate control theory as large fiber another is stimuation produced analgesia as small diameter fier. 6. In DNIC, the stimulation sources are mechanical, thermal, heating, pain and acupuncture stimulation etc. we call these as a Heterotopic Noxious Stimulation. 7. In DNIC, SRD(Subnucleus reticularis dorsalis)is core nucleus in pain imtermediated analgesic mechanism. 8. Takeshige insisted nonacupuncture point dependent analgesic mechanism and acupuncture point dependent analgesic mechanism. and protested that Stimulation acupuncture piing evoke blocking nomacupuncture point analgesic pathway.

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Review of Pain Potential Substance and Action Mechanism (통증유발물질과 작용기전에 대한 고찰)

  • Bae, Sung-Soo;Kim, Ho-Bong;Lee, Sang-Yong;Kim, Eun-Young
    • The Journal of Korean Physical Therapy
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    • v.13 no.1
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    • pp.205-218
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    • 2001
  • Interpretation of pain by the patients and the observers as well as the methods of treatment remain as varied as are the concepts of pain. The physiologic mechanism of pain is undergoing a serious revision. It is nociceptive receptive mechanism and Melzak concept of gate theory of pain transmission and etc. Therefore pain depend on the evaluator's learning, experience, or specialty.

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The Cause and Mechanism of Chronic Pain (만성 동통의 원인과 기전)

  • Na, Chul
    • Korean Journal of Psychosomatic Medicine
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    • v.3 no.1
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    • pp.81-90
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    • 1995
  • It is essential in evaluating the chronic pain patients that the physician obtain a multiple causative factors including organic, psychological, and socioenvironmental factors. Though these multiple factors are involved in the development of chronic pain syndrome, chronic pain syndrome is not only the sum of the interaction of all of these factors, but is also influenced by the sequelae of chronic pain, which again are organic, psychological, and socioenvironmental in nature. Therefore a systemic approach is probably the best way to asses the role of all of these factors. Furthermore, this approach can provide a framework for understanding chronic pain syndrome, for assessing chronic pain syndrome, for the rational management of chronic pain syndrome, and for the development and testing of hypotheses.

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Etiology and Mechanism of Neuropathic Pain (일반적인 신경병성 통증의 원인 및 기전)

  • Lim, Hyun-Dae
    • The Journal of the Korean dental association
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    • v.49 no.6
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    • pp.321-326
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    • 2011
  • Neuropathic pain is caused by functional abnonnalities of structural lesions in the peripheral or central nervous system, and occurs without peripheral nociceptor stimulation. Trigeminal neuropathy always pose differential location difficulties as multiple diseases are capablc of producing them: they can be the result of traumatism, tumors, or diseases of the connective tissue, infectious or demyelinating diseases, or may be of idiopathic origin. There are a number of mechanisms described as causing neuropathy. They can be described as ectopic nerve activity, neuroma, ephatic trasmission, change of sodium channel expression, sympathetic activity, central sensitization, and alteration in central inhibition systems. More than I mechanism may be active to create individual clinical presentations. In order to provide better pain control, the mechanism-based approach in treating neuropathic pain should be familiar to physicians.

Literature consideration on pain theory (통증학설에 대한 문헌적 고찰)

  • Kim, Sung-Won
    • Journal of Korean Physical Therapy Science
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    • v.9 no.1
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    • pp.153-158
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    • 2002
  • Pain, which is the most significant issue for the physical therapist, is the cause of various diseases until it disappears, and results in a lot of obstructions to treatment. Pain is very complicated. It is a subjective symptom that informs of a pathologic condition in the body, and one of the unpleasant experiences that people have. It is accompanied with anxiety and fear. Many researchers including Krause(1987) have identified the pain mechanism based on pain perception for many centuries and they have suggested many theories as they believed that pain management was possible. Reviewing the contents of psychoanalysis, uncontrollable pain that can't be explained is described as a defense mechanism to an unconscious psychological conflict. That is, mental pain is transferred to the body and the pain becomes unbearable. What is important is, like Keefe(1992) said, that the pain experience itself is primary stress and one should cope with it, whatever the cause of the pain. This paper investigates the background of the psychological theory of pain. Based on the efforts of previous studies, the next research generation will understand the treatment process for pain more dearly and will contribute to the prevention and protection from pain that humans undergo.

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Korean Pain Descriptors in Patients with Neuromusculoskeletal Pain (신경근골격계 환자들의 한국어 통증 표현)

  • Park, Gi-Young;Kwon, Dong Rak;Woo, In Ho
    • Clinical Pain
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    • v.18 no.2
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    • pp.82-87
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    • 2019
  • Objective: To evaluate which Korean pain descriptors are frequently used in the patients with neuromusculoskeletal diseases and compare the frequency of Korean pain descriptor according to age, gender, pain pattern and intensity, and clinical diagnosis. Method: Two hundreds sixty nine patients with neuromusculoskeletal diseases were enrolled in this study. The patients were asked to fill out a pain questionnaire using Korean. The Korean pain descriptors were collected and classified according to neurophysiological mechanism. The frequency of Korean pain descriptor was analyzed by age, gender, pain pattern and intensity, and clinical diagnosis. They were divided into axial spine and peripheral joint pain group depending on the location of causal disease and shoulder pain descriptors were divided into intra-articular and bursa group. Results: Among 24 Korean pain descriptors, 'arida' was the most common pain descriptor, followed by 'ssusida' and 'jjireunda'. When the pain descriptors were classified according to neurophysiological mechanism, superficial somatic pain was the most common, followed by deep somatic pain. There was a significant difference in the frequency of the pain descriptor between axial spine and peripheral joint pain group (p=0.007). The pain descriptor 'danggida' was used significantly more in the patients with axial spine pain than peripheral joint pain (p=0.024). However, there was no significant difference in other factors. Conclusion: The patients with neuromusculoskeletal diseases expressed their pain using various Korean pain descriptors with stabbing nature and superficial somatic pain. Our results may be helpful to assess and develop a new Korean pain quality measure in the patients with neuromusculoskeletal diseases.