• Title/Summary/Keyword: PTM

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A study on the extended TCP/IP protocol for real-time communication (실시간 통신을 위한 확장된 TCP/IP 프로토콜 개발에 관한 연구)

  • Yoon, Young-Chan;Park, Jae-Hyun
    • Journal of IKEEE
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    • v.2 no.1 s.2
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    • pp.42-52
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    • 1998
  • This paper proposes an extended TCP/IP protocol, LAN/TCP, that can be used for the distributed soft real-time systems connected through the Ethernet-based local area network. Since LAN/TCP shows soft real-time performance with keeping compatibility and interoperability with the standard TCP/IP, the existing application software can be used without any modification. LAN/TCP also provides the periodic transmission mode(PTM) with which the periodical data collection and updating the control signals can be efficiently implemented with relatively small traffic overhead. This paper includes the computer simulation and experimental results of the proposed protocol.

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In vivo putative O-GlcNAcylation of human SCP1 and evidence for possible role of its N-terminal disordered structure

  • Koo, JaeHyung;Bahk, Young Yil
    • BMB Reports
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    • v.47 no.10
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    • pp.593-598
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    • 2014
  • RNA polymerase II carboxyl-terminal domain (RNAPII CTD) phosphatases are responsible for the dephosphorylation of the C-terminal domain of the small subunit of RNAPII in eukaryotes. Recently, we demonstrated the identification of several interacting partners with human small CTD phosphatase1 (hSCP1) and the substrate specificity to delineate an appearance of the dephosphorylation catalyzed by SCP1. In this study, using the established cells for inducibly expressing hSCP1 proteins, we monitored the modification of ${\beta}$-O-linked N-acetylglucosamine (O-GlcNAc). O-GlcNAcylation is one of the most common post-translational modifications (PTMs). To gain insight into the PTM of hSCP1, we used the Western blot, immunoprecipitation, succinylayed wheat germ agglutinin-precipitation, liquid chromatography-mass spectrometry analyses, and site-directed mutagenesis and identified the $Ser^{41}$ residue of hSCP1 as the O-GlcNAc modification site. These results suggest that hSCP1 may be an O-GlcNAcylated protein in vivo, and its N-terminus may function a possible role in the PTM, providing a scaffold for binding the protein(s).

Comparative Compressional Behavior of Zeolite-W in Different Pressure-transmitting Media (제올라이트-W의 압력전달매개체에 따른 체적탄성률 비교 연구)

  • Seoung, Donghoon;Kim, Hyeonsu;Kim, Pyosang;Lee, Yongmoon
    • Korean Journal of Mineralogy and Petrology
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    • v.34 no.3
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    • pp.169-176
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    • 2021
  • This study aimed to fundamentally understand structural changes of zeolite under pressure and in the presence of different pressure-transmitting media (PTM) for application studies such as immobilization of heavy metal cation or CO2 storage using pressure. High-pressure X-ray powder diffraction study was conducted on the zeolite-W (K6.4Al6.5Si25.8O64× 15.3H2O, K-MER) to understand linear compressibility and the bulk moduli in different PTM conditions. Zeolite-w is a synthetic material having the same framework as natural zeolite merlinoite ((K, Ca0.5, Ba0.5, Na)10 Al10Si22O64× 22H2O). The space group of the sample was identified as I4/mmm belonging to the tetragonal crystal system. Water, carbon dioxide, and silicone-oil were used as pressure-transmitting media. The mixture of sample and each PTM was mounted in a diamond anvil cell (DAC) and then pressurized up to 3 GPa with an increment of ca. 0.5 GPa. Pressure-induced changes of powder diffraction patterns were measured using a synchrotron X-ray light source. Lattice constants, and bulk moduli were calculated using the Le-Bail method and the Birch-Murnaghan equation. In all PTM conditions, linear compressibility of c-axis (𝛽c) was 0.006(1) GPa-1 or 0.007(1) GPa-1. On the other hand, the linear compressibility of a(b)-axis (𝛽a) was 0.013(1) GPa-1 in silicone-oil run, which is twice more compressible than the a(b)-axis in water and carbon dioxide runs, 𝛽a = 0.006(1) GPa-1. The bulk moduli were measured as 50(3) GPa, 52(3) GPa, and 29(2) GPa in water, carbon dioxide, and silicone-oil run, respectively. The orthorhombicities of ac-plane in the water, and carbon dioxide runs were comparatively constant, near 0.350~0.353, whereas the value decreased abruptly in the silicone-oil run following formula, y = -0.005(1)x + 0.351(1) by non-penetrating pressure fluid condition.

Anisotropic Compression Behavior and Phase Transition of Sepiolite Under Moderate Pressure Conditions (천부지권 압력 하 해포석의 비등방적 압축 특성 및 상전이 연구)

  • Seohee, Yun;Yongjae, Lee
    • Korean Journal of Mineralogy and Petrology
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    • v.35 no.4
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    • pp.423-430
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    • 2022
  • Pressure-dependent elastic behavior and chemical reaction of natural sepiolite (Mg8Si12O30(OH)4·12H2O) was studied under two different pressure-transmitting medium (PTM) conditions using synchrotron X-ray powder diffraction. Under non pore-penetrating silicone oil PTM, we observed that the b-axis length increases up to ca. 3.6 GPa, marking an anisotropic compression region with negative linear compressibility of βb= -0.0012 GPa-1, which then decreases at 7.7 GPa. Under pore-penetrating water PTM, the anisotropic compression behavior is enhanced with doubled negative linear compressibility of βb= -0.0025 GPa-1 up to 3.2 GPa, where transformation into stevensite is observed upon ex-situ temperature treatment at 280 ℃ as confirmed via XRD and SEM. Derived bulk moduli (K0) and linear compressibilities (β) were compared to other structurally and chemically related minerals.

Comparison of dental porcelain baking methods by base-alloy and bonding strength by thermocycling (Base-Alloy에 따른 치과 도재의 소성방법과 열순환에 따른 결합강도 비교)

  • Kim, Im-Sun;Min, Kyung-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.2
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    • pp.772-779
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    • 2010
  • This study measured the bonding strength of various porcelain prosthesis materials before and after thermocycling to select prosthesis materials that can maximize beauty and tolerance. To measure bonding strength, various porcelain materials were baked on with-Beryllium metals, non-Beryllium metals 8group and Zirconia 1 group among commercially available base alloys, and measured the bonding strength was measured before and after thermocycling. The findings of this study are as follows: 1) PTM(press-to-metal) porcelain non-Beryllium metal showed the, highteat bonding strength each 73.2MPa, 59.2MPa before and after thermocycling. 2) The porcelain materials baked on non-Beryllium metal showed higher bonding strength before and after thermocycling than those baked on with-Beryllium metal. 3) Zirconia products showed the lowest 38.7MPa bonding strength before and after thermocycling.

A COMPARATIVE STUDY OF CRANIOFACIAL MORPHOLOGY OF PARENTS WITH AND WITHOUT CLEFT LIP AND/OR PALATE CHILDREN (순열ㆍ구개열 환자 부모와 정상 성인의 두개안면 형태에 관한 비교 연구)

  • Lim Sug-Young;Koh Kwang-Joon
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.23 no.1
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    • pp.103-114
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    • 1993
  • The purpose of this study was to determine whether any difference existed in craniofacial morphology between parents of children with cleft lip and/or palate and parents of children without cleft lip and/or palate as well as the characteristics of craniofacial morphology in parents of children with cleft lip and/or palate. Thirty three measurements of the various regions of cranium and face were obtained from lateral cephalometric radiograms in parents of 28 children with cleft lip and palate, 18 children with cleft lip, and 22 children with cleft palate. There were 28 couples and 40 single parents in this sample. There were 92 individuals including 41 males and 51 females. The measurements were compared with those in control subjects, including 40 adult males and 40 adult females, who had no history of craniofacial abnormalities. The total sample was compared for the sex independently. The obtained results were as follows. 1. In the cranium, both parents of cleft children had significantly shorter posterior cranial base length(S-Ba). 2. In the upper face, a significantly shorter anteroposterior length of maxilla(A'-Ptm'), particularly in the anterior region (A'-K), anterior facial depth(A-SBaL), posterior facia! height(Ptm'-SNL) and relation of subnasale to the cranial base (∠BaN'Sn) were noted in fathers of cleft children. But, all measurements were not found to be significantly different between experimental group and control group in all mothers. 3. In the lower face, both parents of cleft children showed a significantly greater Y axis angle(∠NSGn) and ramal plane angle(∠SNL-RP) in fathers of cleft children. Thus both patents showed a posteriorly rotation of mandible. The thickness of the lower lip(B-B') was significantly thicker in fathers of cleft children. 4. In the facial profile, a significantly shorter posterior facial height(S-Go) and greater angle of soft tissue facial convexity (∠BaN'Pog') were noted in the fathers of cleft children. But, all measurements were not found to be significantly different between experimental group and control group in all mothers.

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Malignancy after Pediatric Kidney Transplantation: The 30-Year Experience of a Single Center

  • Jung, Jiwon;Park, Young Seo;Han, Duck Jong
    • Childhood Kidney Diseases
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    • v.24 no.2
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    • pp.75-82
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    • 2020
  • Objectives: We aimed to investigate the incidence, manifestations, and outcomes of malignancy after pediatric kidney transplantation (KT) at our center over 30 years. Methods: We retrospectively reviewed the medical records of 155 patients under 18 years of age who underwent KT between January 1990 and February 2020 at Asan Medical Center. Results: Twelve patients (7.7%) were diagnosed with a malignancy after KT. Malignancy was diagnosed after a mean period of 6.4±5.9 years (median 4.6, range 0.5-20.6 years) after KT. Nine (75.0%) of the 12 cancer patients were diagnosed with post-transplant lymphoproliferative disease (PTLD), and the other three had papillary thyroid cancer, mucoepidermoid cancer of the hard palate, and T-cell acute lymphoblastic leukemia, respectively. PTLD was diagnosed within a mean of 3.7±3.4 years (median 3.7, range 0.5-9.8 years) after KT. Five patients diagnosed with PTLD were cured without recurrence. Three patients with PTLD died from the disease, and one patient with mucoepidermoid cancer from a non-PTLD malignancy died after progression, despite surgical resection and chemotherapy. Three (33.3%) of the nine survivors progressed to end-stage renal disease (ESRD) after completing cancer treatment. No patient with post-transplant malignancy (PTM) experienced critical renal deterioration during cancer treatment. Conclusion: PTLD was the most common PTM, occurring at 5.8% of the pediatric KT patients after KT in our center. Careful follow up is needed particularly considering the risk of PTLD after KT in children.

Low Power Reliable Asynchronous Digital Circuit Design for Sensor System (센서 시스템을 위한 저전력 고신뢰의 비동기 디지털 회로 설계)

  • Ahn, Jihyuk;Kim, Kyung Ki
    • Journal of Sensor Science and Technology
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    • v.26 no.3
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    • pp.209-213
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    • 2017
  • The delay-insensitive Null Convention Logic (NCL) asynchronous design as one of innovative asynchronous logic design methodologies has many advantages of inherent robustness, power consumption, and easy design reuses. However, transistor-level structures of conventional NCL gate cells have weakness of high area overhead and high power consumption. This paper proposes a new NCL gate based on power gating structure. The proposed $4{\times}4$ NCL multiplier based on power gating structure is compared to the conventional NCL $4{\times}4$ multiplier and MTNCL(Multi-Threshold NCL) $4{\times}4$ multiplier in terms of speed, power consumption, energy and size using PTM 45 nm technology.

Replacement of Hexachlorocyclohexane to Environmentally Friendly Biosurfactant as Precursor for the Production of Biosurfactant from Pseudomonas

  • Anu Appaiah, K.A.;Parvathy, A.;Mathew, Mariam;Karanth, N.G.K.
    • Journal of Microbiology and Biotechnology
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    • v.21 no.8
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    • pp.858-860
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    • 2011
  • Production of biosurfactant can be substantially increased by the addition of precursors like vegetable oils, petroleum products, and other water-insoluble substances. Pseudomonas Ptm+ strain produces biosurfactant in the presence of hexachlorocyclohexane (HCH), which specifically emulsifies HCH, a recalcitrant organochlorine pesticide. Addition of previously produced crude biosurfactant by the same organism as a precursor instead of HCH increased production of biosurfactants with a decrease in the total fermentation time from 32 to 24 h. The main objective of this paper was to find alternatives for HCH as an inducer.

The Effect of Typhoons on Red Tide (태풍이 적조에 미치는 영향)

  • Hong, Chul-Hoon
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.50 no.2
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    • pp.222-226
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    • 2017
  • It is well known that typhoons strongly influence marine ecosystems. For example, red tides nearly disappear after the passage of typhoons, although the physical or biological mechanism underlying this has not been elucidated. Here, a particle tracking model is executed in a three-dimensional primitive equation model to understand the process of red tide extinction after the passage of a typhoon. Red tide organisms may be regarded as tracers because they have limited mobility and thus their behavior is governed entirely by currents. Initially, tracers are randomly scattered within a limited area, and their spatial and temporal behavior is tracked during and after the passage of a typhoon. This model suggests that the extinction of red tides is significantly influenced by momentum disturbances caused by the typhoon.