• Journal of Korean Society for Quality Management
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• v.41 no.3
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• pp.487-494
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• 2013

Purpose: In this study, we propose the precision guided munitions verification methodology using the statistical analysis method has been proposed. and it can be applied to the precision guided munitions quality assurance work. Methods: This modeling is based on Failure Mode and Effects Analysis, Statistical Process Control, Defense Quality Managerment System, Production Readiness Review, Manufacturing Readiness Assesment and so on. Results: The Process Control Modeling that has the following procedures ; searching the critical to quality, statistical analysis by process, verify process. Moreover, the effectiveness of the methodology is verified by applying to the precision guided munitions. Conclusion: To achieve a analysis methods of statistical process control and verify process for precision guided munitions.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.11a
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• pp.531-532
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• 2009

위치기반 라우팅 기법들은 소스에서 목적지노드로 데이터 패킷을 전송하기 위한 목적으로 널리 사용된다. 오리지널 그리디 포워딩 기법은 실제 무선링크의 신뢰성을 고려하지 않아 수많은 데이터 패킷 재전송이 발생한다. 이러한 문제를 해결하기 위해 PRR ${\times}$ Distance 기법이 제안되었지만 실제 무선링크의 비대칭성을 고려하지 않아 여전히 많은 재전송이 발생한다. 제안기법은 포워딩할 데이터 패킷을 가진 현재 노드의 전송 반경 내에서 전송 가능한 1-hop과 2-hop 라우팅 경로를 찾는다. 이들 라우팅 경로들 중 기대전송비용이 최소가 되는 경로를 선택하여 데이터와 ACK 패킷을 전송한다. 시뮬레이션을 결과를 통해 제안기법이 기존 기법들보다 높은 신뢰성과 에너지 효율을 가짐을 보인다.

• Biomolecules & Therapeutics
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• v.31 no.4
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• pp.395-401
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• 2023

Innate immunity is a first line defence system in the body which is for sensing signals of danger such as pathogenic microbes or host-derived signals of cellular stress. Pattern recognition receptors (PRR's), which present in the cell memebrane, are suspect the infection through pathogen-associated molecular patterns (PAMP), and activate innate immunity with response to promote inflammation via inflammatory cells such as macrophages and neutrophils, and cytokines. Inflammasome are protein complexes which are part of innate immunity in inflammation to remove pathogens and repair damaged tissues. What is the important role of inflammation in disease? In this review, we are focused on the action mechanism of NLRP3 inflammasome in inflammatory diseases such as asthma, atopic dermatitis, and sepsis.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.68 no.3
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• pp.134-146
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• 2023

Phytophthora root rot (PRR) is a major soybean disease caused by an oomycete, Phytophthora sojae. PRR can be severe in poorly drained fields or wet soils. The disease management primarily relies on resistance genes called Rps (resistance to P. sojae). This study aimed to identify resistance loci associated with resistance to P. sojae isolate 40468 in Daepung × CheonAl recombinant inbred line (RIL) population. CheonAl is resistant to the isolate, while Daepung is generally susceptible. We genotyped the parents and RIL population via high-throughput single nucleotide polymorphism genotyping and constructed a set of genetic maps. The presence or absence of resistance to P. sojae was evaluated via hypocotyl inoculation technique, and phenotypic distribution fit to a ratio of 1:1 (R:S) (χ² = 0.57, p = 0.75), indicating single gene mediated inheritance. Single-marker association and the linkage analysis identified a highly significant genomic region of 55.9~56.4 megabase pairs on chromosome 18 that explained ~98% of phenotypic variance. Many previous studies have reported several Rps genes in this region, and also it contains nine genes that are annotated to code leucine-rich repeat or serine/threonine kinase within the approximate 500 kilobase pairs interval based on the reference genome database. CheonAl is the first domestic soybean genotype characterized for resistance against P. sojae isolate 40468. Therefore, CheonAl could be a valuable genetic source for breeding resistance to P. sojae.

• Journal of the korean academy of Pediatric Dentistry
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• v.36 no.1
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• pp.53-61
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• 2009

The property of pit and fissure sealant has been improved and many studies on the bond strength, penetration, microleakage have been published. But there are few studies on the using status and perception of pit and fissure sealant within the country. Therefore, this study made a survey on it. Pedodontists and non-pedodontists were surveyed by interview. The Results were as follows; 1. On caries prevention effect, 96.7% of the pedodontists replied that sealants were effective on both permanent teeth and primary teeth. On the other hand, 13.5% of the non-pedodontists replied that sealants weren't effective on both. 2. All of the pedodontists and 27% of the non-pedodontists used rubber dams. 83.3% of the pedodontists and 40.5% of the non-pedodontists used bonding agents. 3. Non-pedodontists used enameloplasty more frequently than Pedodontists but the pattern was not significantly different. 4. The causes of sealant failures included salivary contamination, caries under sealant, low strength, low flowability, overfilling. 5. In the pedodontists, 90% replied that PRR application was desirable and PRR applications were more frequent than sealant application.

• Korean Journal of Clinical Pharmacy
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• v.24 no.1
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• pp.39-44
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• 2014

Purpose: To investigate adverse drug reactions (ADR) and causative drugs in the elderly 65 years of age or older, using Korean spontaneous reporting adverse events reporting database from June 2009 to December 2010. Methods: We estimated the association between ADRs and implicated medications by calculating a proportional reporting ratio (PRR), reporting odds ratio (ROR), and information component (IC). We reexamined the most frequently implicated medications and ADRs, and the seriousness of ADRs. Then, we assessed reports and concordant rate of ADRs due to medications designated as "high-risk" in elderly by 2012 healthcare effectiveness data and information set (HEDIS) or "potentially inappropriate" by 2012 American Geriatrics Society updated Beers criteria for potentially inappropriate medications (PIMs). Results: Among 15,484 elderly reports, data-mining analysis by PRR, ROR and IC showed that 421 drug-ADR pairs were detected as signals (3,189). The most frequently reported ADR and causative drug were urticaria (470) and contrast media agents (647), respectively. One hundred eighty nine ADR cases were graded as serious. Twenty-two kinds of high-risk medications were shown to be implicated in only 0.9% of ADRs. Only thirty-nine cases were consistent with 2012 Beers criteria or HEDIS. Conclusion: These results suggest that management of the other medications including contrast media agents as well as close monitoring of PIMs are necessary for reducing ADRs in the elderly.

• International Journal of Oral Biology
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• v.33 no.4
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• pp.163-177
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• 2008

Periodontal disease, a form of chronic inflammatory bacterial infectious disease, is known to be a risk factor for cardiovascular disease (CVD). Porphyromonas gingivalis has been implicated in periodontal disease and widely studied for its role in the pathogenesis of CVD. A previous study demonstrating that periodontopathic P. gingivalis is involved in CVD showed that invasion of endothelial cells by the bacterium is accompanied by an increase in cytokine production, which may result in vascular atherosclerotic changes. The present study was performed in order to further elucidate the role of P. gingivalis in the process of atherosclerosis and CVD. For this purpose, invasion of human aortic smooth muscle cells (HASMC) by P. gingivalis 381 and its isogenic mutants of KDP150 ($fimA^-$), CW120 ($ppk^-$) and KS7 ($relA^-$) was assessed using a metronidazole protection assay. Wild type P. gingivalis invaded HASMCs with an efficiency of 0.12%. In contrast, KDP150 failed to demonstrate any invasive ability. CW120 and KS7 showed relatively higher invasion efficiencies, but results for these variants were still negligible when compared to the wild type invasiveness. These results suggest that fimbriae are required for invasion and that energy metabolism in association with regulatory genes involved in stress and stringent response may also be important for this process. ELISA assays revealed that the invasive P. gingivalis 381 increased production of the proinflammatory cytokine interleukin (IL)-$1{\beta}$ and the chemotactic cytokines (chemokine) IL (interleukin)-8 and monocyte chemotactic (MCP) protein-1 during the 30-90 min incubation periods (P<0.05). Expression of RANTES (regulation upon activation, normal T cell expressed and secreted) and Toll-like receptor (TLR)-4, a pattern recognition receptor (PRR), was increased in HASMCs infected with P. gingivalis 381 by RT-PCR analysis. P. gingivalis infection did not alter interferon-$\gamma$-inducible protein-10 expression in HASMCs. HASMC nonspecific necrosis and apoptotic cell death were measured by lactate dehydrogenase (LDH) and caspase activity assays, respectively. LDH release from HASMCs and HAMC caspase activity were significantly higher after a 90 min incubation with P. gingivalis 381. Taken together, P. gingivalis invasion of HASMCs induces inflammatory cytokine production, apoptotic cell death, and expression of TLR-4, a PRR which may react with the bacterial molecules and induce the expression of the chemokines IL-8, MCP-1 and RANTES. Overall, these results suggest that invasive P. gingivalis may participate in the pathogenesis of atherosclerosis, leading to CVD.

• The KIPS Transactions:PartB
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• v.13B no.3 s.106
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• pp.295-300
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• 2006

The integral imaging system is an auto-stereoscopic display that allows users to see 3D images without wearing special glasses. In the integral imaging system, the 3D object information is taken from several view points and stored as elemental images. Then, users can see a 3D reconstructed image by the elemental images displayed through a lens array. The elemental images can be created by computer graphics, which is referred to the computer-generated integral imaging. The process of creating the elemental images is called image mapping. There are some image mapping methods proposed in the past, such as PRR(Point Retracing Rendering), MVR(Multi-Viewpoint Rendering) and PGR(Parallel Group Rendering). However, they have problems with heavy rendering computations or performance barrier as the number of elemental lenses in the lens array increases. Thus, it is difficult to use them in real-time graphics applications, such as virtual reality or real-time, interactive games. In this paper, we propose a new image mapping method named VVR(Viewpoint Vector Rendering) that improves real-time rendering performance. This paper describes the concept of VVR first and the performance comparison of image mapping process with previous methods. Then, it discusses possible directions for the future improvements.

• Journal of the Korea Society of Computer and Information
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• v.15 no.4
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• pp.83-90
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• 2010

In wireless sensor networks, the data transmitted from the sensor nodes are susceptible to corruption by errors which caused of noisy channels and other factors. In view of the severe energy constraint in Sensor Networks, it is important to use the error control scheme of the energy efficiently. In this paper, we presented RS (Reed-Solomon) codes in terms of their BER performance and power consumption. RS codes work by adding extra redundancy to the data. The encoded data can be stored or transmitted. It could have errors introduced, when the encoded data is recovered. The added redundancy allows a decoder to detect which parts of the received data is corrupted, and corrects them. The number of errors which are able to be corrected by RS code can determine by added redundancy. The results of experiment validate the performance of proposed method to provide high degree of reliability in low-power communication. We could predict the lifetime of RS codes which transmitted at 32 byte a 1 minutes. RS(15, 13), RS(31, 27), RS(63, 57), RS(127,115), and RS(255,239) can keep the days of 173.7, 169.1, 163.9, 150.7, and 149.7 respectively. The evaluation based on packet reception ratio (PRR) indicates that the RS(255,239) extends a sensor node's communication range by up about 3 miters.

• Journal of Navigation and Port Research
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• v.43 no.4
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• pp.231-236
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• 2019

As ships become bigger, faster, and diverse, transportation has increased the usage of marine vehicles. However, ship accidents are increasing. Ship accidents cause loss of life and property as well as environmental disasters. The occurrence of ship accidents causes enormous economic and environmental impacts. Notably, in the case of passenger ships, methods for preventing ship accidents are being discussed to avoid losing numerous human lives. The purpose of this study is to provide essential data for evacuation before reaching the dangerous time by predicting the time to reach the risk of capsizing based on the heeling angle of the passenger ship. Based on sinking accidents between 2012 and 2016, we set up specific scenarios and simulated the PRR1 data using commercial software MOSES V20. In the case of the linear equation, the simulation results showed a low error rate because the simulation data showed the linear graph. In the case of the quadratic equation, the error rate was low at the beginning but showed a high error rate at the subsequent angle.